PFCEA - Overview: Carcinoembryonic Antigen (CEA), Pleural Fluid
An adjuvant to cytology and imaging studies to differentiate between nonmalignant and malignant causes of pleural effusions
CCOC - Overview: Coccidioides Antibody, Complement Fixation and Immunodiffusion, Spinal Fluid
Diagnosing coccidioidomycosis using spinal fluid specimens
BRAFB - Overview: Cell-Free DNA BRAF V600, Blood
An alternative to invasive tissue biopsies for the determination of BRAF V600E and V600K alterations Identification of patients with cancer who are most likely to benefit from targeted therapies This test is not intended for serial...
COSY - Overview: Cobalt, Synovial Fluid
Monitoring metallic prosthetic implant wear and local tissue destruction in failed hip arthroplasty constructs This test is not useful for assessment of nutritional status or potential cobalt toxicity.
T790M - Overview: Cell-Free DNA EGFR T790M Mutation Analysis, Blood
Determination of EGFR T790M mutation status in blood specimens as an alternative to invasive tissue biopsies Identification of patients with non-small cell lung cancer who harbor a T790M mutation and may benefit from specific EGFR-targeted...
EMAIG - Overview: Endomysial Antibodies, IgG, Serum
Analysis of IgG-endomysial antibodies for the diagnosis of dermatitis herpetiformis and celiac disease Monitoring adherence to gluten-free diet in patients with dermatitis herpetiformis and celiac disease
CHAGL - Overview: Trypanosoma cruzi IgG, Lateral Flow Assay, Serum
Diagnosis of chronic Trypanosoma cruzi infection (Chagas disease)
FB12 - Overview: Vitamin B12 and Folate, Serum
Investigation of macrocytic anemia Workup of deficiencies seen in megaloblastic anemias Investigation of suspected folate deficiency
RAVU - Overview: Ravulizumab, Serum
Assessing the response to ravulizumab therapy Assessing the need for dose escalation Evaluating the potential for dose deescalation or discontinuation of therapy in remission states Monitoring patients who need to be above a certain...
Aiding in the diagnosis of Helicobacter pylori infection and prediction of clarithromycin resistance or susceptibility directly from gastric biopsies
FETCE - Overview: Mitochondrial Respiratory Chain Enzyme Analysis (ETC) - Skin Fibroblasts
Mitochondrial Respiratory Chain Enzyme Analysis (ETC) - Skin Fibroblasts
FFTAC - Overview: Thrombin-Antithrombin Complex
Thrombin-Antithrombin Complex
8AINH - Overview: Factor VIII Inhibitor Profile, Professional Interpretation
Interpretation for the detection of the presence and titer of a specific factor inhibitor directed against coagulation factor VIII
FIFLC - Overview: Immunofixation with Free Light Chains, Quantitative, Urine
Immunofixation with Free Light Chains, Quantitative, Urine
FBAC - Overview: Bile Acids, Urine
Bile Acids, Urine
FMMM - Overview: Mephedrone, MDPV and Methylone, Urine
Mephedrone, MDPV and Methylone, Urine
FCPEU - Overview: C-Peptide, 24-Hour Urine
Urine C-peptide is measured when a continuous assessment of B-cell function is desired or frequent blood sampling is not practical (eg, in children). C-peptide excretion in urine has been used to access pancreatic function in gestational...
FSULU - Overview: Thiosulfate, Urine
Thiosulfate, Urine
PATHC - Overview: Pathology Consultation
A subspecialty second opinion for a specific pathology question referred by a primary pathologist Note: A consultative opinion is not a full rendering of a primary diagnostic report (eg, multiple parts, margin status, CAP...
PLPMA - Overview: Prolactin, Pituitary Macroadenoma, Serum
Quantifying prolactin in serum specimens where the high-dose hook effect is suspected (eg, presence of pituitary tumor with symptoms of prolactinoma, and lower than expected serum prolactin concentration)
PBALP - Overview: Porphobilinogen and Aminolevulinic Acid, Plasma
An equivalent option to urine for first-line test for evaluation of a suspected acute porphyria Monitoring patients undergoing treatment for an acute intermittent porphyria or other acute porphyria
VITAE - Overview: Vitamin A and Vitamin E, Serum
Diagnosing vitamin A deficiency and toxicity Evaluating persons with intestinal malabsorption of lipids Monitoring of Vitamin E supplementation/treatment
MTBT - Overview: Mycobacterium tuberculosis Complex, Molecular Detection, PCR, Paraffin, Tissue
Preferred method for rapid detection of Mycobacterium tuberculosis complex DNA in formalin-fixed, paraffin-embedded tissue specimens Detecting M tuberculosis complex This test is not intended for the detection of latent tuberculosis and...
IBDP2 - Overview: Inflammatory Bowel Disease Serology Panel, Serum
Distinguishing between ulcerative colitis and Crohn disease in patients for whom the specific diagnosis is unclear based on endoscopic, pathologic, and imaging evaluations This test is not useful for determining the extent of disease in...
ASOU - Overview: Arsenic Occupational Exposure, Random, Urine
Screening test for detection of occupational exposure to arsenic in random urine specimens
CRCOF - Overview: Chromium and Cobalt, Synovial Fluid
Monitoring metallic prosthetic implant wear and local tissue destruction in failed hip arthroplasty constructs This test is not useful for assessment of vitamin B12 activity.
ASCU - Overview: Arsenic/Creatinine Ratio, Urine
Screening for arsenic exposure using random urine specimens
FIERA - Overview: IgE Receptor Antibody
The test detects functional autoantibodies to the Fc-epsilon receptor (high affinity IgE receptor) or to IgE and is useful in the evaluation of chronic urticaria.
ABONR - Overview: ABO/Rh Newborn, Blood
Selecting compatible blood products for transfusion therapy Determining the need for Rh immune globulin in mother of baby
MITAN - Overview: Mitotane, Plasma
Assessing compliance or making dosage adjustments for mitotane
FCZAC - Overview: Certolizumab and Anti-Certolizumab Antibody, DoseASSURE CTZ
Provides certolizumab drug concentration and anti-certolizumab antibodies in order to optimize treatment and facilitate clinical decision-making. This assay may be helpful in any patient on certolizumab therapy for Crohn's disease,...
APRI - Overview: Prolonged Clot Time Profile Interpretation
Interpretation of testing performed as part of a profile to determine the cause of prolongation of prothrombin time or activated partial thromboplastin time Interpretation of testing performed as part of a profile for screening for...
Detecting lead exposure using nail specimens
Identification of breast and urinary cancer, among others
LAGGT - Overview: Granulocyte Antibodies, Serum
Work-up of individuals having febrile, nonhemolytic transfusion reactions Detection of individuals with autoimmune neutropenia This test is not useful for the diagnosis of neutropenia caused by marrow suppression by drugs or tumors.
MSFNG - Overview: Fibronectin Glomerulopathy Confirmation, Mass Spectrometry
Aiding in the diagnosis of fibronectin glomerulopathy
8INHT - Overview: Factor VIII Inhibitor Profile, Technical Interpretation
Technical interpretation of inhibitor to factor VIII testing This test is not useful for the detection of a lupus-like circulating anticoagulant inhibitor, a nonspecific circulating anticoagulant, or other inhibitors that are not specific...
HGOU - Overview: Mercury Occupational Exposure, Random, Urine
Detecting mercury toxicity due to occupational exposure in random urine specimens
CRSBF - Overview: Crystal Identification, Body Fluid
Identifying the presence and type of crystals in body fluid
FDA1S - Overview: Drugs of Abuse (10 panel) and Alcohol Screen, Serum
Drugs of Abuse (10 panel) and Alcohol Screen, Serum
FIBDD - Overview: PROMETHEUS IBD sgi Diagnostic
PROMETHEUS IBD sgi Diagnostic
SLYME - Overview: Lyme Antibody Modified 2-Tier with Reflex, Serum
Diagnosis of Lyme disease This test should not be used as a screening procedure for the general population.
RT3 - Overview: T3 (Triiodothyronine), Reverse, Serum
Aiding in the diagnosis of the sick euthyroid syndrome
HKC - Overview: Hexokinase Enzyme Activity, Blood
The evaluation of individuals with Coombs-negative chronic hemolysis
LEU - Overview: Fecal Leukocytes, Feces
Suggesting the presence of pathogens such as Salmonella, Shigella, and amebiasis
PBOU - Overview: Lead Occupational Exposure, Random, Urine
Detecting clinically significant lead exposure due to occupational exposure in random urine specimens This test is not a substitute for blood lead screening.
SEWB - Overview: Selenium, Blood
Assessment of tissue stores of selenium
FSCPR - Overview: Scleroderma Comprehensive Profile
Scleroderma Comprehensive Profile
DCTR - Overview: Direct Antiglobulin Test (Polyspecific), Blood
Demonstrating in vivo coating of red blood cells with IgG or the complement component C3d in the following settings: -Autoimmune hemolytic anemia -Hemolytic transfusion reactions -Drug-induced hemolytic anemia
CDP - Overview: Chlordiazepoxide and Metabolite, Serum
Monitoring chlordiazepoxide therapy Assessing toxicity
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Detection of (1→3)-𝝱-D-glucan as a Marker of Invasive Fungal Disease - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....