Interpretation for the detection of the presence and titer of a specific factor inhibitor directed against coagulation factor VIII
Only orderable as a reflex. For more information see 8INHE / Factor VIII Inhibitor Evaluation, Plasma
Medical Interpretation
Factor 8 Inhibitor Profile
Plasma Na Cit
Only orderable as a reflex. For more information see 8INHE / Factor VIII Inhibitor Evaluation, Plasma.
Only orderable as a reflex. For more information see 8INHE / Factor VIII Inhibitor Evaluation, Plasma.
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Plasma Na Cit | Frozen | 14 days |
Interpretation for the detection of the presence and titer of a specific factor inhibitor directed against coagulation factor VIII
Factor VIII (FVIII) inhibitors are IgG antibodies directed against coagulation FVIII that typically result in development of potentially life-threatening hemorrhage. These antibodies may develop in 1 of 4 different patient populations:
-Patients with congenital FVIII deficiency (hemophilia A) in response to therapeutic infusions of factor VIII concentrate
-Elderly non-hemophiliac patients (not previously factor VIII deficient)
-Women in postpartum period
-Patients with other autoimmune illnesses
Only orderable as a reflex. For more information see 8INHE / Factor VIII Inhibitor Evaluation, Plasma.
An interpretive report will be provided.
An interpretive report will be provided when testing is complete.
No significant cautionary statements
1. Kasper CK: Treatment of factor VIII inhibitors. Prog Hemost Thromb 1989;9:57-86
2. Peerschke EI, Castellone DD, Ledford-Kraemer M, et al: Laboratory assessment of FVIII inhibitor titer. Am J Clin Pathol 2009;131(4):552-558
3. Pruthi RK, Nichols WL: Autoimmune factor VIII inhibitors. Curr Opin Hematol 1999;6(5):314-322
4. Laboratory Hematology Practice. Edited by K Kottke-Marchant. Wiley Blackwell Publishing, 2012
A coagulation expert (clinician or hematopathologist) reviews the laboratory data and an interpretive report is issued.
Monday through Friday
Not Applicable
85390-26
Test Id | Test Order Name | Order LOINC Value |
---|---|---|
8AINH | FVIII Inhib Profile Prof Interp | 69049-5 |
Result Id | Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
---|---|---|
607486 | Reviewed by | 18771-6 |
607442 | FVIII Inhib Profile Prof Interp | 69049-5 |