PLSD - Overview: Lysosomal and Peroxisomal Disorders Screen, Blood Spot
Evaluation of patients with a clinical presentation suggestive of a lysosomal disorder, specifically Gaucher, infantile neurovisceral or chronic visceral acid sphingomyelinase deficiency,, Pompe, Krabbe, or Fabry disease, or...
Risk stratification of patients with treated multiple myeloma, which can assist in determining treatment and management decisions Risk stratification of patients with newly diagnosed multiple myeloma
IDTRT - Overview: IDH1, IDH2, and TERT Mutation Analysis, Next-Generation Sequencing, Tumor
Identifying specific mutations within the IDH1 and IDH2 genes and the TERT promoter to assist in tumor diagnosis/classification
Second-tier testing of newborns with an abnormal primary screening result for mucopolysaccharidosis type I (MPS I, decreased alpha-L-iduronidase activity) where quantitation of the glycosaminoglycans dermatan and heparan sulfate is desired...
MYEFL - Overview: Myelodysplastic Syndrome by Flow Cytometry, Bone Marrow
Detecting increased blasts Characterizing blast phenotypes Identifying abnormal patterns of myeloid maturation as seen in myelodysplastic syndromes and other clonal myeloid neoplasms Providing additional adjunct diagnostic information in...
MESOF - Overview: Mesothelioma, CDKN2A FISH, Tissue
Supporting the diagnosis of mesothelioma when used in conjunction with an anatomic pathology consultation
Risk stratification of patients with treated multiple myeloma, which can assist in determining treatment and management decisions Risk stratification of patients with newly diagnosed multiple myeloma
TTRX - Overview: Amyloidosis, Transthyretin-Associated Familial, Reflex, Blood
Diagnosis of adult individuals suspected of having transthyretin-associated familial amyloidosis
BRCAT - Overview: BRCA1/2 Mutation Analysis, Next-Generation Sequencing, Tumor
Identifying specific mutations within the BRCA1 and BRCA2 genes known to be associated with response to PARP inhibitors and sensitivity to platinum-based therapy This test is not intended for the evaluation of patients suspected of having...
MB2GP - Overview: Beta-2 Glycoprotein 1 Antibodies, IgM, Serum
Evaluating patients with suspected antiphospholipid syndrome by identification of beta-2 glycoprotein 1 IgM antibodies First-line test when antiphospholipid syndrome is strongly suspected in conjunction with cardiolipin antibodies (IgG...
GB2GP - Overview: Beta-2 Glycoprotein 1 Antibodies, IgG, Serum
Evaluating patients with suspected antiphospholipid syndrome by identification of beta-2 glycoprotein 1 IgG antibodies First-line test when antiphospholipid syndrome is strongly suspected, in conjunction with cardiolipin antibodies (IgG...
BRFKT - Overview: BRAF and KIT Mutation Analysis, Next-Generation Sequencing, Tumor
Identifying specific mutations within the BRAF and KIT genes that predict response to therapy
BRAZR - Overview: Brazil Nut, IgE with Reflex to Brazil Nut Component, IgE, Serum
Evaluation of patients with suspected Brazil nut allergy
CLLMF - Overview: Chronic Lymphocytic Leukemia, Specified FISH, Varies
Detecting recurrent common chromosome abnormalities in patients with chronic lymphocytic leukemia (CLL) Distinguishing patients with 11;14 translocations who have the leukemic phase of mantle cell lymphoma from patients who have CLL...
Venison IgE
FDILT - Overview: Diltiazem (Cardizem, Dilacor)
Diltiazem (Cardizem, Dilacor)
AD2AR - Overview: PrecivityAD2, Reflex to Apolipoprotein E, Plasma
Assisting in the evaluation of adult patients, aged 55 years and older, with signs or symptoms of mild cognitive impairment or dementia who are being assessed for Alzheimer disease and other causes of cognitive decline Determining APOE E4...
STHPV - Overview: ThinPrep Screen with Human Papillomavirus (HPV) Reflex, Varies
Managing and triaging of patients, aged 21 years or older, with abnormal Pap results Screening for detection of high-risk (HR) human papillomavirus (HPV) genotypes associated with the development of cervical cancer Aids in triaging...
DTHPV - Overview: ThinPrep Diagnostic with Human Papillomavirus (HPV) Reflex, Varies
Management and triage of patients aged 21 years or older with abnormal Papanicolaou (Pap) results Diagnostic test for detection of human papillomavirus (HPV) high-risk genotypes associated with the development of cervical cancer Results...
Establishing a molecular diagnosis for patients with frontotemporal dementia (FTD) and/or amyotrophic lateral sclerosis (ALS) Identifying variants within genes known to be associated with FTD and/or ALS, allowing for predictive testing of...
PINP - Overview: Procollagen I Intact N-Terminal, Serum
Aiding in monitoring antiresorptive and anabolic therapy in patients with osteoporosis An adjunct in the assessment of conditions associated with increased bone turnover, such as Paget disease This test should not be used as a screening...
OCT4 - Overview: OCT3/4 Immunostain, Technical Component Only
Identification of germ cell tumors
POU2F - Overview: POU2F3 Immunostain, Technical Component Only
Diagnosis of a variant of small cell lung carcinoma
PAS8 - Overview: Pediatric Allergy Screen >8 Years, Serum
Establishing a diagnosis of an allergy to pediatric allergy screen Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm...
Identification of neoplasms expressing programmed cell death 1-ligand 1 (clone SP142)
B6PA - Overview: Pyridoxic Acid, Plasma
Determining the concentration of pyridoxic acid in the assessment of vitamin B6 status
TRAP - Overview: Tartrate-Resistant Acid Phosphatase (TRAP) Immunostain, Technical Component Only
Classification of leukemias and lymphomas
WNGC - Overview: West Nile Virus Antibody, IgG, Spinal Fluid
Aids in diagnosing recent or past central nervous system West Nile virus infection
WNGS - Overview: West Nile Virus Antibody, IgG, Serum
Detection of IgG antibodies in West Nile virus infections
ZNU - Overview: Zinc, 24 Hour, Urine
Identifying the cause of abnormal serum zinc concentrations using 24-hour urine specimens
VEGF - Overview: Vascular Endothelial Growth Factor, Plasma
Evaluation of patients with suspected POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome, particularly in differentiating from other forms of polyneuropathy and/or monoclonal plasma cell...
IDH1 - Overview: IDH1 Mutation (R132H) Immunostain, Technical Component Only
Classification of gliomas
IL5P - Overview: Interleukin 5, Plasma
Evaluation of patients with disorders known to be associated with hypereosinophilia
ORTHP - Overview: Orthostatic Proteinuria, Random, Urine
Diagnosis of orthostatic proteinuria
GAL2 - Overview: Probability of Hepatocellular Carcinoma, Serum
Calculation of the risk for patients with chronic liver disease to develop hepatocellular carcinoma
CSPCF - Overview: Plasma Cell Proliferative Disorder, Pre-Analysis Cell Sorting, Bone Marrow
Aiding in the diagnosis of new cases of multiple myeloma or other plasma cell proliferative disorders Sorting plasma cells for fluorescence in situ hybridization analysis
PTH - Overview: Parathyroid Hormone (PTH) Immunostain, Technical Component Only
Identification of parathyroid glands
RB1 - Overview: Retinoblastoma Protein (Rb) Immunostain, Tech Only
Aids in the identification of high-grade neuroendocrine carcinomas and small cell carcinomas
SORD - Overview: Sorbitol and Xylitol, Quantitative, Random, Urine
Screening for sorbitol dehydrogenase deficiency-related neuropathy
TSH - Overview: Thyroid-Stimulating Hormone (TSH), Beta Immunostain, Technical Component Only
Part of a panel of immunostains used in the classification of pituitary adenomas
SES - Overview: Selenium, Serum
Monitoring selenium replacement therapy
HPYL - Overview: Helicobacter pylori (H pylori) Immunostain, Technical Component Only
Aiding in the identification of Helicobacter pylori infection
SMAT - Overview: Smooth Muscle Antibody Titer, Serum
Antibody titer testing as a part of the evaluation of patients with hepatitis of unknown origin associated with hypergammaglobulinemia and/or abnormal liver enzymes
HEMMF - Overview: Hematologic Specified FISH, Varies
The detection of specific chromosomal abnormalities in hematologic malignancies
Determining class II human leukocyte antigens (HLA) to identify potential disease associations or markers for drug hypersensitivity
IMIPR - Overview: Imipramine and Desipramine, Serum
Monitoring imipramine and desipramine concentrations during therapy Evaluating potential imipramine and desipramine toxicity May aid in evaluating patient compliance
GAL1 - Overview: GALAD Score, Serum
Calculation of the GALAD (gender, age, alpha-fetoprotein L3% [AFP-L3], AFP, des-gamma-carboxy prothrombin) model score for hepatocellular carcinoma development in patients with chronic liver disease
LGBWB - Overview: Globotriaosylsphingosine, Blood
Screening of patients with Fabry disease when a serum specimen is not available This test should not be used for newborn screening followup.
GRAS1 - Overview: Grass Panel # 1, Serum
Establishing a diagnosis of an allergy to June/Kentucky blue, meadow fescue, orchard, rye, and timothy Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or...
GRAS2 - Overview: Grass Panel # 2, Serum
Establishing a diagnosis of an allergy to Bahia, Bermuda, Johnson, June/Kentucky blue, rye, and timothy Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or...
Week in Review: February 3 - Insights
Include: President Biden to End Covid-19 Emergencies On May 11, and Children’s Minnesota Received $3 Million Grant To Address Pediatric Health Disparities....
Leveraging the Laboratory Archives - Page 3 of 3 - Insights
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Detection of (1→3)-𝝱-D-glucan as a Marker of Invasive Fungal Disease - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections....
Phlebotomy Modules: Module 3 | Insights
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Week in Review: March 3 - Insights
Today's Highlights Include: COVID-19 deaths remain low compared to previous winters, FDA authorizing first at-home combo flu/Covid test, and Rochester public schools evaluating mental health needs and services throughout the district.