PYRC - Overview: Pyruvate, Spinal Fluid

Investigating possible disorders of mitochondrial metabolism, when used in conjunction with cerebrospinal fluid lactate, collected at the same time, to determine the lactate-to-pyruvate (L:P) ratio Evaluating patients with neurologic...

PBALP - Overview: Porphobilinogen and Aminolevulinic Acid, Plasma

An equivalent option to urine for first-line test for evaluation of a suspected acute porphyria Monitoring patients undergoing treatment for an acute intermittent porphyria or other acute porphyria

TRYPT - Overview: Tryptase, Serum

Evaluation of individuals with suspected mast cell activation, which may occur as a result of anaphylaxis or allergen challenge Evaluation of patients with suspected mast cell activation syndrome Evaluation of patients with suspected...

VMA - Overview: Vanillylmandelic Acid, 24 Hour, Urine

Screening children for catecholamine-secreting tumors using a 24-hour urine collection when requesting testing for vanillylmandelic acid only Supporting a diagnosis of neuroblastoma Monitoring patients with a treated neuroblastoma

VWFMS - Overview: von Willebrand Factor Multimer Analysis, Plasma

Resolving discrepancies when results of complementary laboratory tests (eg, F8A / Coagulation Factor VIII Activity Assay, Plasma; VWACT / von Willebrand Factor Activity, Plasma; and VWAG / von Willebrand Factor Antigen, Plasma) are...

ASMW - Overview: Acid Sphingomyelinase, Leukocytes

Investigation of possible diagnosis of Niemann-Pick disease types A and B This test is not recommended for carrier detection because of the wide range of enzymatic activities observed in carriers and noncarriers.

EGWTP - Overview: Egg White Component Profile, Serum

Identifying egg white allergens: -Responsible for allergic disease and/or anaphylactic episode -To confirm sensitization prior to beginning immunotherapy This test is not useful for patients previously treated with immunotherapy to...

RNP - Overview: RNP Antibodies, IgG, Serum

Evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive Testing for ribonucleoprotein particle antibodies is not useful in patients without demonstrable...

FRDIG - Overview: Digoxin, Free, Serum

Evaluating recrudescent (breakthrough) digoxin toxicity in renal-failure patients Assessing the need for more antidigoxin Fab to be administered Deciding when to reintroduce digoxin therapy Monitoring patients with possible...

USTEK - Overview: Ustekinumab Quantitation with Antibodies, Serum

Evaluation of loss of response to therapy Quantification of ustekinumab in human serum Trough level quantitation for evaluation of patients treated with ustekinumab Detection of antibodies to ustekinumab in human serum

HL58R - Overview: HLA-B*5801 Genotype, Allopurinol Hypersensitivity, Varies

Identifying individuals with an increased risk of severe cutaneous adverse reactions to allopurinol based on the presence of the human leukocyte antigen HLA-B*58:01 allele

HBABT - Overview: Hepatitis B Virus Surface Antibody Monitor, Post-Transplant, Serum

Monitoring serum hepatitis B virus surface antibody levels during intravenous or intramuscular hepatitis B immune globulin therapy to prevent hepatitis B virus reinfection in liver transplant recipients with known previous chronic hepatitis...

IL6DX - Overview: Interleukin-6, Serum

Evaluating patients with suspected chronic inflammatory disorders, such as rheumatoid arthritis, systemic lupus erythematosus, ankylosing spondylitis, or inflammatory bowel disease Evaluating patients with Castleman disease Evaluating...

GMCSF - Overview: Granulocyte Monocyte-Colony Stimulating Factor, Plasma

Measuring the concentration of granulocyte macrophage-colony stimulating factor (GM-CSF) in plasma Understanding the etiology of chronic inflammatory diseases or infections, when used in conjunction with clinical information and other...

HAVTA - Overview: Hepatitis A Virus Total Antibodies, Serum

Detection of recent or previous exposure or immunity to hepatitis A. This test should not be used as a screening or confirmatory test for blood or solid or soft tissue donor specimens.

2INHE - Overview: Factor II Inhibitor Evaluation, Plasma

Detection and quantitation of inhibitor to factor II This test is not useful for the detection of a lupus-like circulating anticoagulant inhibitor, a nonspecific circulating anticoagulant, or other inhibitors that are not specific for...

5INHE - Overview: Factor V Inhibitor Evaluation, Plasma

Detection and quantitation of inhibitors against coagulation factor V This test is not useful for the detection of a lupus-like circulating anticoagulant inhibitor, a nonspecific circulating anticoagulant, or other inhibitors that are not...

FFRBS - Overview: Friedreich Ataxia, Frataxin, Quantitative, Blood Spot

Diagnosing individuals with Friedreich ataxia in blood spot specimens Monitoring frataxin levels in patients with Friedreich ataxia This test is not useful for carrier detection.

LPALD - Overview: Lipoprotein (a) and Low-Density Lipoprotein Cholesterol, Serum

Evaluation of the contribution of lipoprotein (a) (Lp[a])-cholesterol within measured low-density lipoprotein cholesterol Evaluation of increased risk for cardiovascular disease and events: -Most appropriately measured in individuals at...

JO1 - Overview: Jo 1 Antibodies, IgG, Serum

Evaluating patients with clinical features of idiopathic inflammatory myositis, especially those with clinical features suggestive of anti-synthetase syndrome or interstitial lung disease

GAAW - Overview: Acid Alpha-Glucosidase, Leukocytes

Diagnosis of Pompe disease

ADVQU - Overview: Adenovirus DNA Detection and Quantification, Plasma

Aiding in the diagnosis of disseminated adenovirus infections in at-risk individuals Measuring adenoviral load in plasma to monitor disease progression and antiviral response in individuals with disseminated infection

ALDNA - Overview: Aldosterone with Sodium, 24 Hour, Urine

Investigating primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (eg, renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter...

BA48F - Overview: Bile Acids, Bowel Dysfunction, 48 Hour, Feces

Aids in evaluation of patients suspected of having irritable bowel syndrome-diarrhea symptoms due to bile acid malabsorption

BALLM - Overview: B-Cell Lymphoblastic Leukemia Monitoring, Minimal Residual Disease Detection, Flow Cytometry, Varies

Aids in monitoring a previously confirmed diagnosis of B-cell acute lymphoblastic leukemia

LCMSP - Overview: Microsporidia species, Molecular Detection, PCR, Varies

Detecting Enterocytozoon bieneusi and Encephalitozoon species in fecal and urine specimens to support the clinical diagnosis of microsporidiosis

RO52 - Overview: Ro52 Antibody, IgG, Serum

Evaluating patients at risk for connective tissue disease with or without interstitial lung disease Differentiating single vs double positivity for Ro52 and Ro60 antibodies in combination with anti-Ro60

PMET - Overview: Metanephrines, Fractionated, Free, Plasma

Screening test for presumptive diagnosis of catecholamine-secreting pheochromocytomas or paragangliomas

TWRP - Overview: Tropheryma whipplei, Molecular Detection, PCR, Varies

Aiding in the diagnosis of Whipple disease, especially for identifying inconclusive or suspicious cases, using tissue or fluid specimens

RISAP - Overview: Risankizumab Quantitation with Antibodies, Serum

Evaluation of patients with limited primary (initial) response to or secondary loss of response to risankizumab

RO60 - Overview: Ro60 Antibody, IgG, Serum

Evaluating patients at risk for connective tissue disease with or without interstitial lung disease Differentiating single vs double positivity for Ro52 and Ro60 antibodies in combination with anti-Ro60

SM - Overview: Smith (Sm) Antibodies, IgG, Serum

Evaluating patients with clinical features suggestive of antinuclear antibody associated connective tissue disease and the confirmation of a diagnosis of systemic lupus erythematosus. Testing for Smith antibodies is not useful in patients...

TCGRV - Overview: T-Cell Receptor Gene Rearrangement, PCR, Varies

Determining whether a T-cell population is polyclonal or monoclonal using body fluid or tissue specimens

CORTU - Overview: Cortisol, Free, 24 Hour, Urine

Preferred screening test for Cushing syndrome Diagnosis of pseudo-hyperaldosteronism due to excessive licorice consumption Test may not be useful in the evaluation of adrenal insufficiency.

IN16Q - Overview: CBFB::MYH11 Inversion(16), Quantitative Detection and Minimal Disease Risk Monitoring, qRT-PCR, Varies

Detection of CBFB::MYH11 gene fusion in patients recently diagnosed with acute myeloid leukemia (AML) Minimal residual disease monitoring during the clinical and therapeutic course of patients with AML

CJDEI - Overview: Creutzfeldt-Jakob Disease Evaluation Interpretation, Spinal Fluid

Interpretation of the Creutzfeldt-Jakob Disease Evaluation

COWB - Overview: Cobalt, Blood

Monitoring exposure to cobalt using whole blood specimens Monitoring metallic prosthetic implant wear This test is not useful for assessment of vitamin B12 activity.

PF199 - Overview: Carbohydrate Antigen 19-9 (CA 19-9), Pleural Fluid

An adjuvant to cytology and imaging studies to differentiate between nonmalignant and malignant causes of pleural effusions

CARBI - Overview: Carbapenem Resistance Genes, Molecular Detection, PCR, Varies

Detecting and differentiating blaKPC, blaNDM, blaVIM, blaOXA-48, and blaIMP gene sequences associated with carbapenem intermediate or resistant results Aiding in infection control in the detection of gastrointestinal colonization of...

CRITH - Overview: DNA Double-Stranded (dsDNA) Antibodies by Crithidia luciliae IFA, IgG, Serum

Confirmation testing for dsDNA IgG antibodies in patients with clinical features of systemic lupus erythematosus or at-risk for disease This test should not be used independently for monitoring treatment response or establishing...

BCGRV - Overview: Immunoglobulin Gene Rearrangement, PCR, Varies

Determining whether a B-cell or plasma cell population is polyclonal or monoclonal in specimens other than blood or bone marrow Identifying neoplastic cells as having B-cell or plasma cell differentiation Monitoring for a persistent...

BPAB - Overview: Bullous Pemphigoid, BP180 and BP230, IgG Antibodies, Serum

Initial screening test in the diagnosis of bullous pemphigoid and its variants Complementing the standard serum test of indirect immunofluorescence utilizing primate esophagus substrate and primate salt-split skin substrate (CIFS /...

AATTA - Overview: Antithrombin Summary Interpretation

Diagnosis of antithrombin deficiency, acquired or congenital Monitoring treatment of antithrombin deficiency disorders, including infusion of antithrombin therapeutic concentrate

ANIDE - Overview: Organism Referred for Identification, Anaerobic Bacteria

Identifying anaerobic bacteria involved in human infections

KRASD - Overview: Cell-Free DNA KRAS 12, 13, 61,146, Blood

An alternative to invasive tissue biopsies for the determination of KRAS 12, 13, 61,146 (G12A, G12C, G12D, G12R, G12S, G12V, G13D, Q61K, Q61L, Q61R, Q61H, and A146T) mutation status Detecting molecular markers associated with response or...

SFGP - Overview: Spotted Fever Group Antibody, IgG and IgM, Serum

Aiding in the diagnosis of spotted fever group rickettsial infections

OAU - Overview: Organic Acids Screen, Random, Urine

Diagnosis of inborn errors of metabolism

RNAP - Overview: RNA Polymerase III Antibodies, IgG, Serum

Evaluating patients suspected of having systemic sclerosis as part of systemic sclerosis criteria antibody tests Providing diagnostic and prognostic information in patients with systemic sclerosis

11INE - Overview: Factor XI Inhibitor Evaluation, Plasma

Detection and quantitation of inhibitor to coagulation factor XI This test is not useful for the detection of a lupus-like circulating anticoagulant inhibitor, a nonspecific circulating anticoagulant, or other inhibitors that are not...

LALBS - Overview: Lysosomal Acid Lipase, Blood Spot

Evaluation of patients with a clinical presentation suggestive of lysosomal acid lipase deficiency using blood spot specimens This test is not useful to determine carrier status for cholesteryl ester storage disease or Wolman disease.