RETZZ - Overview: Multiple Endocrine Neoplasia Type 2 Syndrome, RET, Full Gene Analysis, Varies
Evaluating patients with a personal or family history suggestive of a multiple endocrine neoplasia type 2 (MEN2) or Hirschsprung disease (HSCR) Establishing a diagnosis of MEN2 or HSCR allowing for targeted cancer surveillance based on...
CATPF - Overview: Cat Epithelium, IgE, with Reflex to Cat Epithelium Components, IgE, Serum
Evaluating patients with suspected cat allergy
CRTS1 - Overview: Creatinine with Estimated Glomerular Filtration Rate (eGFR), Serum
Diagnosing and monitoring treatment of acute and chronic kidney diseases Adjusting dosage of renally excreted medications Monitoring kidney transplant recipients Estimating glomerular filtration rate for people with chronic kidney...
SMNDX - Overview: Spinal Muscular Atrophy Diagnostic Assay, Deletion/Duplication Analysis, Varies
First-tier newborn screening for spinal muscular atrophy (SMA) Prenatal testing for SMA Diagnostic testing to confirm a suspected diagnosis of SMA
CDKZ - Overview: CDKN1C Gene, Full Gene Analysis, Varies
Confirming a clinical diagnosis of Beckwith-Wiedemann syndrome following a normal result on methylation analysis Confirming a clinical diagnosis of IMAGe (intrauterine growth restriction, metaphyseal dysplasia, adrenal hypoplasia...
JIP - Overview: Joint Infection Panel, PCR, Synovial Fluid
Rapid detection of synovial fluid infections caused by the following: Anaerococcus prevotii/vaginalis Finegoldia magna Streptococcus species Clostridium perfringens Parvimonas micra Streptococcus agalactiae Cutibacterium...
PARVO - Overview: Parvovirus B19, Molecular Detection, PCR, Varies
Diagnosing parvovirus B19 infection
TRYPT - Overview: Tryptase, Serum
Evaluation of individuals with suspected mast cell activation, which may occur as a result of anaphylaxis or allergen challenge Evaluation of patients with suspected mast cell activation syndrome Evaluation of patients with suspected...
HMGCR - Overview: 3-Hydroxy-3-Methylglutaryl Coenzyme-A (HMG-CoA) Reductase, Serum
Evaluating patients with suspected necrotizing autoimmune myopathy Measuring 3-hydroxy-3-methylglutaryl-CoA reductase antibodies
TYRSC - Overview: Tyrosinemia Follow-Up Panel, Self-Collect, Blood Spot
Monitoring of individuals with tyrosinemia type I (hepatorenal tyrosinemia) using a patient-collected specimen
HSVPB - Overview: Herpes Simplex Virus (HSV), Molecular Detection, PCR, Blood
Aiding in the rapid diagnosis of disseminated disease due to herpes simplex virus (HSV) Qualitative detection of HSV DNA This test should not be used to screen asymptomatic patients.
FACT - Overview: Filamentous-Actin (F-actin) Antibody, IgG, Serum
Evaluation of patients with hepatitis of unknown origin associated with hypergammaglobulinemia and/or abnormal liver enzymes This test may also be useful for confirming positivity for smooth muscle antibodies.
FFRBS - Overview: Friedreich Ataxia, Frataxin, Quantitative, Blood Spot
Diagnosing individuals with Friedreich ataxia in blood spot specimens Monitoring frataxin levels in patients with Friedreich ataxia This test is not useful for carrier detection.
LKM - Overview: Liver/Kidney Microsome Type 1 Antibodies, Serum
Evaluation of patients with liver disease of unknown etiology Evaluation of patients with suspected autoimmune hepatitis
LDBF - Overview: Lactate Dehydrogenase (LDH), Body Fluid
Identification of exudative pleural effusions Lactate dehydrogenase in pericardial fluids is not diagnostically useful.
JAK2B - Overview: JAK2 V617F Mutation Detection, Blood
Aiding in the distinction between a reactive blood cytosis and a chronic myeloproliferative disorder using peripheral blood specimens
Detecting Mycoplasma genitalium in cases of suspected infection in peritoneal fluid or prostatic secretion (VBIII) fluid/urine This test is not intended for use in medico-legal applications.
MPS3W - Overview: Mucopolysaccharidosis III, Four-Enzyme Panel, Leukocytes
Supporting the biochemical diagnosis of mucopolysaccharidoses types IIIA, IIIB, IIIC, IIID This test is not useful for carrier detection.
ALLOI - Overview: Allo-isoleucine, Blood Spot
Evaluation of newborn screening specimens that test positive for branched-chain amino acids elevations Follow-up of patients with maple syrup urine disease
BA48F - Overview: Bile Acids, Bowel Dysfunction, 48 Hour, Feces
Aids in evaluation of patients suspected of having irritable bowel syndrome-diarrhea symptoms due to bile acid malabsorption
BETV2 - Overview: BET v2 (Profilin), IgE, Serum
Evaluation of patients suspected birch pollen allergy Evaluation of patients with suspected peanut allergy Evaluation of patients with oral allergy syndrome to other pollens or plant-based foods Testing for IgE antibodies is not useful...
CAMPC - Overview: Campylobacter Culture, Feces
Determining whether Campylobacter species may be the cause of diarrhea Reflexive testing for Campylobacter species from nucleic acid amplification test-positive feces This test is generally not useful for patients hospitalized more than...
Q10 - Overview: Coenzyme Q10, Reduced and Total, Plasma
Diagnosis of primary coenzyme Q10 (CoQ10) deficiencies in some patients who are not supplemented with CoQ10 Diagnosis of CoQ10 deficiency in mitochondrial disorders Monitoring CoQ10 status during treatment of various degenerative...
Confirming the presence or absence of minimal residual disease in patients with known chronic lymphocytic leukemia who are either post-chemo/immunotherapy or post-bone marrow transplant
RO52 - Overview: Ro52 Antibody, IgG, Serum
Evaluating patients at risk for connective tissue disease with or without interstitial lung disease Differentiating single vs double positivity for Ro52 and Ro60 antibodies in combination with anti-Ro60
MPO - Overview: Myeloperoxidase Antibodies, IgG, Serum
Evaluating patients with clinical features anti-neutrophil cytoplasmic antibody associated vasculitis, specifically granulomatosis with polyangiitis, microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis...
RO60 - Overview: Ro60 Antibody, IgG, Serum
Evaluating patients at risk for connective tissue disease with or without interstitial lung disease Differentiating single vs double positivity for Ro52 and Ro60 antibodies in combination with anti-Ro60
SM - Overview: Smith (Sm) Antibodies, IgG, Serum
Evaluating patients with clinical features suggestive of antinuclear antibody associated connective tissue disease and the confirmation of a diagnosis of systemic lupus erythematosus. Testing for Smith antibodies is not useful in patients...
CHRTI - Overview: Chromosome Analysis, Skin Biopsy
Diagnosis of mosaic congenital chromosome abnormalities, including mosaic aneuploidy and mosaic structural abnormalities Subsequent chromosome analysis when results from peripheral blood are inconclusive
CH9 - Overview: Chromogenic Factor IX Activity Assay, Plasma
Monitoring coagulation factor replacement therapy of selected extended half-life coagulation factor replacements Aiding in the diagnosis of hemophilia B using a 2-stage assay, especially when a 1-stage assay was normal
CYPAN - Overview: Cytokine Panel, Plasma
Understanding the etiology of infectious or chronic inflammatory diseases, when used in conjunction with clinical information and other laboratory testing Research studies in which an assessment of cytokine responses is needed
CJDEI - Overview: Creutzfeldt-Jakob Disease Evaluation Interpretation, Spinal Fluid
Interpretation of the Creutzfeldt-Jakob Disease Evaluation
C341Q - Overview: Complement C3 and C4 with Anti-C1q Antibodies, Serum
Evaluating patients with suspected anti-C1q vasculitis Predicting renal involvement in patients with systemic lupus erythematosus
C1INF - Overview: C1 Esterase Inhibitor, Functional, Serum
Diagnosing hereditary angioedema Monitoring response to C1 esterase inhibitor replacement therapy
SFIG - Overview: Cerebrospinal Fluid IgG Index Profile, Serum and Spinal Fluid
Aiding in the diagnosis of multiple sclerosis and other central nervous system inflammatory conditions
DNSAG - Overview: Dengue Virus NS1 Antigen, Serum
Aiding in the diagnosis of dengue virus infection
CRITH - Overview: DNA Double-Stranded (dsDNA) Antibodies by Crithidia luciliae IFA, IgG, Serum
Confirmation testing for dsDNA IgG antibodies in patients with clinical features of systemic lupus erythematosus or at-risk for disease This test should not be used independently for monitoring treatment response or establishing...
VWAG - Overview: von Willebrand Factor Antigen, Plasma
Diagnosis of von Willebrand disease (VWD) and differentiation of VWD subtype (in conjunction with von Willebrand factor ristocetin cofactor activity and factor VIII coagulant activity) Differentiation of VWD from hemophilia A (in...
JAK2M - Overview: JAK2 V617F Mutation Detection, Bone Marrow
Aiding in the distinction between a reactive blood cytosis and a chronic myeloproliferative disorder using bone marrow specimens
LALBS - Overview: Lysosomal Acid Lipase, Blood Spot
Evaluation of patients with a clinical presentation suggestive of lysosomal acid lipase deficiency using blood spot specimens This test is not useful to determine carrier status for cholesteryl ester storage disease or Wolman disease.
ZW186 - Overview: Miscellaneous University of Chicago Genetics Sernices
Miscellaneous University of Chicago Genetics Sernices
FPLAC - Overview: PROMETHEUS LactoTYPE
PROMETHEUS LactoTYPE
FDLS - Overview: Donath Landsteiner
Donath Landsteiner
RPB - Overview: Respiratory Panel, PCR, Varies
Rapid detection of respiratory infections caused by the following: -Adenovirus -Coronavirus serotypes HKU1, NL63, 229E, OC43 -SARS-CoV-2 -Human metapneumovirus -Human rhinovirus/enterovirus -Influenza A subtypes H1, H1-2009, H3, influenza A...
HMDB - Overview: Heavy Metals Screen with Demographics, Blood
Detecting exposure to arsenic, lead, cadmium, and mercury
COMCP - Overview: Hereditary Common Cancer Panel, Varies
Evaluating hereditary cancer for patients with a personal or family history suggestive of a hereditary cancer syndrome using a panel of 36 genes Establishing a diagnosis of a hereditary cancer syndrome allowing for targeted cancer...
MSUDP - Overview: Maple Syrup Urine Disease Gene Panel, Varies
Follow up for abnormal biochemical results suggestive of maple syrup urine disease (MSUD) Establishing a molecular diagnosis for patients with MSUD Identifying variants within genes known to be associated with MSUD, allowing for...
DHR - Overview: Dihydrorhodamine Flow Cytometric Test, Blood
Evaluation of chronic granulomatous disease (CGD), X-linked and autosomal recessive forms, Rac2 deficiency, complete myeloperoxidase deficiency Monitoring chimerism and nicotinamide adenine dinucleotide phosphate oxidase (NOX) function...
PMND1 - Overview: Primary Membranous Nephropathy Diagnostic Cascade, Serum
Distinguishing primary from secondary membranous nephropathy using an algorithmic approach Monitoring patients with membranous nephropathy at very low antibody titers Screening for anti-phospholipase A2 receptor antibodies
TOXGP - Overview: Toxoplasma gondii Antibody, IgG, Serum
Determining whether a patient has had previous exposure to or recent infection with Toxoplasma gondii This test is not useful for diagnosing infection in infants younger than 6 months of age. In that age group, IgG antibodies usually are...
Learn how our cystatin C testing provides an index of glomerular filtration rate, which is the best indicator of overall kidney health and function....
Hepatitis C Virus Genotypic Antiviral Drug Resistance [Test in Focus] - Insights
Joseph Yao, M.D., gives an overview of this new test available through Mayo Clinic Laboratories. He discusses when this testing should be ordered, how this testing improves upon other testing approaches, and what clinical action can be...
testing_algorithm_for_the_screening_and_diagnosis_of_hepatitis_c.pdf
Education and Research (MFMER). All rights reserved. 02/2022 Hepatitis C: Testing Algorithm for Screening and Diagnosis HCVQN / Hepatitis C Virus (HCV) RNA Detection and Quantification by Real-Time Reverse...
https://news.mayocliniclabs.com/mc2775-782/
FO U R RE AL -W O RL D C O LL AB O RA TI VE E XA M PL ES to Mayo Clinic diagnostics C O N N E C T I N G Pharma and biotech TABLE OF CONTENTS What makes a good testing partner? Case study 1 Gastrointestinal...
Algorithms - Mayo Clinic Laboratories
Algorithms A B C D E F G H I J