ALPGP - Overview: Alport Syndrome Gene Panel, Varies
Providing a genetic evaluation for patients with a personal or family history suggestive of Alport syndrome Establishing a diagnosis of Alport syndrome
Diagnostic workup of patients with high probability of BCR::ABL1-positive hematopoietic neoplasms, predominantly chronic myeloid/myelogenous leukemia and acute lymphoblastic leukemia
CHIMS - Overview: Chimerism Transplant Sorted Cells, Varies
Determining the relative amounts of donor and recipient cells in a specimen in sorted cell fractions An indicator of bone marrow transplant success
CHIMU - Overview: Chimerism Transplant No Cell Sort, Varies
Determining the relative amounts of donor and recipient cells in a specimen An indicator of bone marrow transplant success
GNVWD - Overview: von Willebrand Disease, VWF and GP1BA Genes, Next-Generation Sequencing, Varies
Evaluating von Willebrand disease and platelet-type von Willebrand disease in patients with a personal or family history suggestive of von Willebrand disease Confirming von Willebrand disease or platelet-type von Willebrand disease...
SCIDP - Overview: Severe Combined Immunodeficiency (SCID) Gene Panel, Varies
Establishing a diagnosis of a severe combined immunodeficiency (SCID) associated with known causal genes Identifying variants within genes known to be associated with SCID, allowing for predictive testing of at-risk family members and/or...
PHI11 - Overview: Prostate Health Index Reflex, Serum
As an aid in distinguishing prostate cancer from benign prostatic conditions in men aged 50 years and older with total PSA between 4.0 and 10.0 ng/mL and digital rectal examination findings that are not suspicious for cancer
MFBNG - Overview: FBN1 Full Gene Sequencing with Deletion/Duplication, Varies
Providing a genetic evaluation for patients with a personal or family history suggestive of Marfan syndrome and other FBN1-related conditions Establishing a diagnosis for Marfan syndrome and other FBN1-related conditions
Providing a genetic evaluation for patients with a personal or family history suggestive of a hereditary form of dilated cardiomyopathy or left ventricular noncompaction Establishing a diagnosis of a hereditary form dilated cardiomyopathy...
CDKZ - Overview: CDKN1C Gene, Full Gene Analysis, Varies
Confirming a clinical diagnosis of Beckwith-Wiedemann syndrome following a normal result on methylation analysis Confirming a clinical diagnosis of IMAGe (intrauterine growth restriction, metaphyseal dysplasia, adrenal hypoplasia...
Providing a genetic evaluation for patients with a personal or family history of steroid resistant nephrotic syndrome (SRNS) Establishing a diagnosis of hereditary SRNS Guiding treatment decisions in individuals with nephrotic syndrome
HPVE6 - Overview: Human Papillomavirus (HPV) High-Risk E6/E7, RNA In Situ Hybridization
Stratification of oropharyngeal squamous cell carcinoma
ALS - Overview: Aldolase, Serum
Detection of muscle disease
SOLFM - Overview: Soluble Fibrin Monomer, Plasma
Assisting in the diagnosis of arterial or venous prethrombotic states in various pathological and clinical situations including disseminated intravascular coagulation/intravascular coagulation and fibrinolysis and postoperative monitoring...
DOXA1 - Overview: Oxalate Analysis, Hemodialysate
Determining the amount of oxalate removed during a dialysis session Individualizing the dialysis prescription of hyperoxaluric patients
OSMOF - Overview: Osmolality, Feces
Measurement of osmolality for the workup of cases of chronic diarrhea Diagnosis of factitious diarrhea (where patient adds fluid to stool to simulate diarrhea)
EPPAN - Overview: Comprehensive Epilepsy With or Without Encephalopathy Gene Panel, Varies
Establishing a diagnosis of an epilepsy or seizure disorder associated with known causal genes Identifying disease-causing variants within genes known to be associated with inherited epilepsy or seizure disorders, allowing for predictive...
NEPHP - Overview: Comprehensive Nephrology Gene Panel, Varies
Providing a genetic evaluation for patients with a personal or family history suggestive of hereditary kidney disease Establishing a diagnosis for a variety of hereditary kidney conditions including focal segmental glomerulosclerosis,...
PLSD - Overview: Lysosomal and Peroxisomal Disorders Screen, Blood Spot
Evaluation of patients with a clinical presentation suggestive of a lysosomal disorder, specifically Gaucher, infantile neurovisceral or chronic visceral acid sphingomyelinase deficiency,, Pompe, Krabbe, or Fabry disease, or...
PRL - Overview: Prolactin, Serum
Aiding in evaluation of pituitary tumors, amenorrhea, galactorrhea, infertility, and hypogonadism Monitoring therapy of prolactin-producing tumors
PC1TC - Overview: Purkinje Cell Cytoplasmic Antibody Type 1 (PCA-1) Titer, Spinal Fluid
Identifying female patients whose subacute cerebellar degeneration or peripheral neuropathy is due to a remote (autoimmune) effect of gynecologic or breast carcinoma Reporting an end titer result from spinal fluid specimens
PC2TS - Overview: Purkinje Cell Cytoplasmic Antibody Type 2 (PCA-2) Titer, Serum
Evaluating patients who present with a subacute neurological disorder of undetermined etiology and have risk factors for lung cancer Reporting an end titer result from serum specimens
PIPU - Overview: Pipecolic Acid, Random, Urine
Differentiating between disorders of peroxisomal biogenesis (eg, Zellweger syndrome) and disorders with loss of a single peroxisomal function Detecting abnormal elevations of pipecolic acid in urine
SMAS - Overview: Smooth Muscle Antibody Screen, Serum
Evaluation of patients with hepatitis of unknown origin associated with hypergammaglobulinemia and/or abnormal liver enzymes
PCTTC - Overview: Purkinje Cell Cytoplasmic Antibody, Type Tr (PCA-Tr) Titer, Spinal Fluid
Serological testing for Purkinje cell cytoplasmic antibody-Tr for patients with acquired cerebellar ataxia of undetermined etiology, particularly if the patient has a history of Hodgkin lymphoma Reporting an end titer result from spinal...
PIPA - Overview: Pipecolic Acid, Serum
Differentiating between disorders of peroxisomal biogenesis (eg, Zellweger syndrome) and disorders with loss of a single peroxisomal function Detecting abnormal elevations of pipecolic acid in serum
RISA - Overview: Risankizumab, Serum
Assessing the response to risankizumab therapy Assessing the need for dose escalation Evaluating potential changes or discontinuation of therapy Monitoring patients who need to be above a certain risankizumab concentration to improve the...
UHBAG - Overview: Histoplasma and Blastomyces Antigen, Enzyme Immunoassay, Urine
Diagnosing Histoplasma capsulatum or Blastomyces dermatitidis infection without differentiation between the organisms Monitor antigen levels following initiation of antifungal treatment
GIAR - Overview: Giardia Antigen, Feces
Sensitive screening for the detection of Giardia antigens present in fecal specimens
FERR1 - Overview: Ferritin, Serum
Aiding in the diagnosis of iron deficiency and iron overload conditions Differentiating iron deficiency anemia and anemia of chronic disease
ESTS - Overview: Estradiol, Rapid, Immunoassay, Serum
Rapid assessment of ovarian status, including follicle development, for assisted reproduction protocols (eg, in vitro fertilization) Establishing time of ovulation and optimal time for conception
FBL - Overview: Fungal Culture, Blood
Diagnosis and treatment of the etiologic agents of fungemia
AN3TC - Overview: Antineuronal Nuclear Antibody Type 3 (ANNA-3) Titer, Spinal Fluid
Evaluating patients who present with a subacute neurological disorder of undetermined etiology and have risk factors for primary lung carcinoma Reporting an end titer result from cerebrospinal fluid specimens
GAPCR - Overview: Streptococcus Group A, Molecular Detection, PCR, Throat
Detecting group A streptococcal infections in patients with signs and symptoms of pharyngitis using a throat swab specimen The test is not intended for monitoring treatment for group A Streptococcus infections.
CTBBL - Overview: Mycobacterial Culture, Blood
Diagnosing mycobacteremia
SSA - Overview: SS-A/Ro Antibodies, IgG, Serum
Evaluating patients at-risk for connective tissue disease with or without interstitial lung disease Detection of both anti-SS-A 52 (Ro52) and SS-A 60 (Ro60) antibodies in serum
SUAC - Overview: Succinylacetone, Blood Spot
Second-tier newborn screen for tyrosinemia type 1 (HT-1) when primary screen showed nonspecific elevations of tyrosine Diagnosing HT-1 when used in conjunction with testing for urine organic acids, liver function, alpha-fetoprotein, and...
Evaluation of Rac2 deficiency and RAC2 gain of function
PFCEA - Overview: Carcinoembryonic Antigen (CEA), Pleural Fluid
An adjuvant to cytology and imaging studies to differentiate between nonmalignant and malignant causes of pleural effusions
CCOC - Overview: Coccidioides Antibody, Complement Fixation and Immunodiffusion, Spinal Fluid
Diagnosing coccidioidomycosis using spinal fluid specimens
FCDSU - Overview: Comprehensive Drug Screen, Umbilical Cord Tissue
Comprehensive Drug Screen, Umbilical Cord Tissue
AN3TS - Overview: Antineuronal Nuclear Antibody Type 3 (ANNA-3) Titer, Serum
Evaluating patients who present with a subacute neurological disorder of undetermined etiology and have risk factors for primary lung carcinoma Reporting an end titer result from serum specimens
PCTTS - Overview: Purkinje Cell Cytoplasmic Antibody Type Tr (PCA-Tr) Titer, Serum
Serological testing for Purkinje cell cytoplasmic antibody-Tr for patients with acquired cerebellar ataxia of undetermined etiology, particularly if the patient has a history of Hodgkin lymphoma Reporting an end titer result from serum...
DASM5 - Overview: Drugs of Abuse Screen, Meconium 5
Identifying amphetamines (and methamphetamines), opiates, phencyclidine, as well as metabolites of cocaine and marijuana in meconium specimens
EEEP - Overview: Eastern Equine Encephalitis Antibody, IgG and IgM, Serum
Aiding in the diagnosis of Eastern equine encephalitis using serum specimens
GLP - Overview: Glucagon, Plasma
Diagnosis and follow-up of glucagonomas and other glucagon-producing tumors Assessing diabetic patients with problematic hyper- or hypoglycemic episodes (extremely limited utility)
DASM4 - Overview: Drugs of Abuse Screen, Meconium 4
Identifying amphetamines (and methamphetamines), opiates, as well as metabolites of cocaine and marijuana in meconium specimens
PLINK - Overview: Paroxysmal Nocturnal Hemoglobinuria, PI-Linked Antigen, Blood
Screening for and confirming the diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) Monitoring patients with PNH
PNBX - Overview: Peripheral Nerve Pathology Consultation
Evaluating diseases of the nerve and disorders that affect nerve function
XHIM - Overview: X-Linked Hyper IgM Syndrome, Blood
Screening for X-linked hyper-IgM (XL-HIGM) or CD40L deficiency, primarily in male patients younger than 10 years Ascertaining XL-HIGM carrier status in women of child-bearing age (younger than 45 years)
Since the pandemic hit, she's spent a great deal of time vetting antibody tests and has set up a COVID-19 testing program at Mayo Clinic....
Staffing to Workload in Phlebotomy Areas: Off-Site Operational Needs - Insights
discusses staffing to workload in phlebotomy areas with a focus on off-site operational needs, including paid time off and unpaid time off....
practices from the program, Mayo Medical Laboratories collaborated with National Decision Support Company (NDSC) to combine Mayo’s clinical knowledge with NDSC’s industry-leading expertise in electronic...
Laboratory and pathology research roundup: August 30 - Insights
This week's research roundup features: Kidney biopsy chronicity grading in antineutrophil cytoplasmic antibody-associated vasculitis...
Visit Mayo Clinic Laboratories at the APA Annual Meeting - Insights
Visit Mayo Clinic Laboratories at booth #2047 to learn about our comprehensive therapeutics test offerings. Developed by board-certified experts in clinical chemistry, molecular, and toxicology testing...