INTAD - Overview: Adalimumab Panel, Interpretation

Interpretation of therapeutic drug monitoring of adalimumab concentration and antibody levels

MCFRC - Overview: MayoComplete Renal Cell Carcinoma with Fibromyomatous Stroma Panel, Next-Generation Sequencing, Tumor

Identifying specific mutations within the ELOC (TCEB1), TSC1, TSC2, and VHL genes to assist in tumor diagnosis/classification Assisting in the clinical management of patients with renal cell carcinoma

SCOF3 - Overview: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) and Influenza Virus Type A and Type B RNA, Molecular Detection, PCR, Varies

Simultaneous detection and differentiation of SARS-CoV-2 (cause of COVID-19), influenza A virus, and influenza B virus in upper or lower respiratory tract specimens from individuals with flu-like illnesses

ACARP - Overview: Acanthamoeba species Molecular Detection, PCR, Ocular

Aids in the diagnosis of amebic keratitis in conjunction with clinical findings

MCLBP - Overview: MayoComplete Liquid Biopsy Panel, Next-Generation Sequencing, Cell-Free DNA

As an alternative to invasive tissue biopsies to assist in tumor profiling for diagnosis, predicting prognosis, and identifying targeted therapies for the treatment and management of patients with solid tumors As an alternative to invasive...

MCGST - Overview: MayoComplete Gastrointestinal Stromal Tumor (GIST) Panel, Next-Generation Sequencing, Tumor

Establishing diagnosis and identifying targeted therapies for patients with gastrointestinal stromal tumors Assessing microsatellite instability

MULT - Overview: Zygosity Testing (Multiple Births), Varies

Determining genetic risk for an individual whose twin or triplet is affected with a genetic disorder for which a specific genetic test is not available (or such testing is uninformative) Assessment of risks prenatally when one fetus of...

C9ORF - Overview: C9orf72 Hexanucleotide Repeat, Molecular Analysis, Varies

Molecular confirmation of clinically suspected cases of c9FTD/ALS, frontotemporal dementia (FTD), or amyotrophic lateral sclerosis (ALS) Presymptomatic testing for individuals with a family history of c9FTD/ALS and a documented expansion...

CRDPU - Overview: Creatine Disorders Panel, Random, Urine

Evaluating patients with a clinical suspicion of arginine:glycine amidinotransferase deficiency, guanidinoacetate methyltransferase deficiency, and creatine transporter deficiency

NGHIS - Overview: MayoComplete Histiocytic Neoplasms, Next-Generation Sequencing, Varies

Aiding in establishing diagnosis, refining prognosis, and potentially identifying targeted therapies for the optimal management of patients with histiocytic neoplasms

GIP - Overview: Gastrointestinal Pathogen Panel, PCR, Feces

Rapid detection of gastrointestinal infections caused by: -Campylobacter species (Campylobacter jejuni/Campylobacter coli/Campylobacter upsaliensis) -Clostridioides difficile toxin A/B -Plesiomonas shigelloides -Salmonella species -Vibrio...

GNBLC - Overview: Bleeding Disorders, Comprehensive Gene Panel, Next-Generation Sequencing, Varies

Evaluating hereditary bleeding in patients with a personal or family history suggestive of a hereditary bleeding disorder Confirming a hereditary bleeding disorder diagnosis with the identification of a known or suspected disease-causing...

TLBLF - Overview: T-Lymphoblastic Leukemia/Lymphoma, FISH, Tissue

Detecting recurrent common chromosome abnormalities associated with T-cell acute lymphoblastic leukemia/lymphoma (T-ALL) using client specified probes Identifying and tracking known chromosome abnormalities in patients with T-ALL and...

LSDGP - Overview: Lysosomal Storage Disease Gene Panel, Varies

Follow up for abnormal biochemical results and confirmation of suspected lysosomal storage disease (LSD) Establishing a molecular diagnosis for patients with LSD Identifying variants within genes known to be associated with LSD, allowing...

CAORG - Overview: Comprehensive Marfan, Loeys-Dietz, Ehlers-Danlos, and Aortopathy Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of hereditary aortic disease Establishing a diagnosis for a variety of hereditary conditions involving aortic disease or overlapping clinical...

GNTHR - Overview: Thrombosis Disorders, Comprehensive Gene Panel, Next-Generation Sequencing, Varies

Evaluating hereditary thrombosis in patients with a personal or family history suggestive of a hereditary thrombosis disorder Confirming a hereditary thrombosis disorder diagnosis with the identification of a known or suspected pathogenic...

THEV1 - Overview: Thalassemia and Hemoglobinopathy Evaluation, Blood and Serum

Evaluation of microcytosis Extensive and economical diagnosis and classification of hemoglobinopathies or thalassemia, including complex disorders Diagnosis of hereditary persistence of hemoglobin

SNS - Overview: Supplemental Newborn Screen, Blood Spot

Presymptomatic identification of disorders to allow for early initiation of treatment and consequent improvement in the long-term prognosis of affected patients The conditions identifiable by amino acid and acylcarnitine analysis are...

PSGN - Overview: Plasminogen Activity, Plasma

Evaluating patients with ligneous conjunctivitis (strong association with homozygous plasminogen deficiency) Evaluating fibrinolysis, in combination with other components of the fibrinolytic system (fibrinogen, tissue...

PIT1 - Overview: PIT-1 Immunostain, Technical Component Only

Classification of pituitary adenomas

PHTDP - Overview: Phosphorylated TDP43 Immunostain, Technical Component Only

Identification of pathological forms of TDP-43 in neurodegenerative diseases

POU2F - Overview: POU2F3 Immunostain, Technical Component Only

Diagnosis of a variant of small cell lung carcinoma

PINS - Overview: Proinsulin, Plasma

As part of the diagnostic workup of suspected insulinoma As part of the diagnostic workup of patients with suspected prohormone convertase 1/3 deficiency As part of the diagnostic workup of patients with suspected proinsulin variations

P62 - Overview: p62 Immunostain, Technical Component Only

Aids in diagnosing argyrophilic grain disease

TRAP - Overview: Tartrate-Resistant Acid Phosphatase (TRAP) Immunostain, Technical Component Only

Classification of leukemias and lymphomas

TYROS - Overview: Tyrosinase (TYROS) Immunostain, Technical Component Only

Aiding in the identification of normal melanocytes and malignant melanoma

VITB3 - Overview: Vitamin B3 and Metabolites, Plasma

Assisting in the diagnosis of suspected vitamin B3 deficiency or toxicity May be useful in determining response to therapy

VZV - Overview: Varicella Zoster Virus (VZV) Immunostain, Technical Component Only

Aids in the identification of varicella zoster virus infection

IDH1 - Overview: IDH1 Mutation (R132H) Immunostain, Technical Component Only

Classification of gliomas

ORTHP - Overview: Orthostatic Proteinuria, Random, Urine

Diagnosis of orthostatic proteinuria

GAL2 - Overview: Probability of Hepatocellular Carcinoma, Serum

Calculation of the risk for patients with chronic liver disease to develop hepatocellular carcinoma

PROG - Overview: Progesterone Receptor (PR) Immunostain, Technical Component Only

Qualitative detection of progesterone receptor protein in a diagnostic setting

RB1 - Overview: Retinoblastoma Protein (Rb) Immunostain, Tech Only

Aids in the identification of high-grade neuroendocrine carcinomas and small cell carcinomas

P57I - Overview: p57 (KIP2/CDKN1C) Immunostain, Technical Component Only

Aids in the identification of cytotrophoblasts, intermediate trophoblasts, and villous stromal cells

P16 - Overview: p16 (INK4a/CDKN2A) Immunostain, Technical Component Only

Aids in the identification of human papilloma virus infection

RSVAB - Overview: Respiratory Syncytial Virus (RSV) In Situ Hybridization, Technical Component Only

Aids in the identification of respiratory syncytial viral infection

CD13 - Overview: CD13 Immunostain, Technical Component Only

Marker of myeloid lineage

PALD - Overview: Aldosterone, Plasma

Investigation of primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter...

CD2 - Overview: CD2 Immunostain, Technical Component Only

Determining T-cell lineage

P63 - Overview: p63 Immunostain, Technical Component Only

Aiding in identifying squamous, urothelial, or myoepithelial differentiation in tumors

SOX11 - Overview: SOX11 Immunostain, Technical Component Only

Identification of mantle cell lymphomas

TBET - Overview: T-Box Expressed in T Cells (TBET) Immunostain, Technical Component Only

Classification of lymphomas

ASYN - Overview: Alpha-Synuclein Immunostain, Technical Component Only

Identification of alpha-synuclein in neurogenerative disorders

ZN_S - Overview: Zinc, Serum

Detecting zinc deficiency

HRPSV - Overview: Herpes Simplex Virus, I and II (HSV I and II) Immunostain, Technical Component Only

Identification of herpes simplex virus I and II infection

HNF1B - Overview: Hepatocyte Nuclear Factor 1Beta Immunostain, Technical Component Only

Diagnosis of ovarian clear cell carcinoma and endometrial clear cell carcinoma

HEMMF - Overview: Hematologic Specified FISH, Varies

The detection of specific chromosomal abnormalities in hematologic malignancies

2DIS - Overview: Human Leukocyte Antigens (HLA)-DR-DQ Disease Association Typing Low Resolution, Blood

Determining class II human leukocyte antigens (HLA) to identify potential disease associations or markers for drug hypersensitivity

HER2I - Overview: HER2 Immunostain, Technical Component Only

Qualitative detection of HER2 protein overexpression in a diagnostic setting in formalin-fixed paraffin-embedded tissue sections

HYPOG - Overview: Hypoglycemic Agent Screen, Serum

Evaluation of suspected insulinoma characterized by hypoglycemia and increased serum insulin concentration Detecting drugs that stimulate insulin secretion Drugs detected by this procedure are: -The first-generation sulfonylureas:...