MPSBS - Overview: Mucopolysaccharidosis, Blood Spot

Supporting the biochemical diagnosis of mucopolysaccharidoses types I, II, III, IV, or VI Quantification of heparan sulfate, dermatan sulfate, and keratan sulfate in dried blood spot specimens

PNEFC - Overview: Neuroimmunology Antibody Follow-up, Spinal Fluid

Monitoring patients who have previously tested positive for 1 or more antibodies within the past 5 years in a Mayo Clinic Neuroimmunology Laboratory spinal fluid evaluation

EOSU1 - Overview: Eosinophils, Random, Urine

Investigation of possible acute interstitial nephritis

FBIOT - Overview: Vitamin B7, H (Biotin)

Vitamin B7, H (Biotin)

DIA - Overview: Diazepam and Nordiazepam, Serum

Assessing compliance Monitoring for appropriate therapeutic level Assessing diazepam toxicity

LEU - Overview: Fecal Leukocytes, Feces

Suggesting the presence of pathogens such as Salmonella, Shigella, and amebiasis

23FBG - Overview: Fibroblast Growth Factor-23 (FGF23), In Situ Hybridization

Assessing fibroblast growth factor-23 (FGF23) expression

CDP - Overview: Chlordiazepoxide and Metabolite, Serum

Monitoring chlordiazepoxide therapy Assessing toxicity

CAFF - Overview: Caffeine, Serum

Monitoring caffeine therapy in neonates Assessing caffeine toxicity in neonates

CZPS - Overview: Clonazepam and 7-Aminoclonazepam, Serum

Assessing patient compliance Monitoring for appropriate therapeutic level Assessing clonazepam toxicity

ETGL - Overview: Ethylene Glycol, Serum

Confirming and monitoring ethylene glycol toxicity

MURA - Overview: Lysozyme (Muramidase), Plasma

As a screening test for ocular sarcoidosis Confirming marked increases in the granulocyte or monocyte pools as in granulocytic or monocytic leukemias, myeloproliferative disorders, and malignant histiocytosis Following the course of...

PBOU - Overview: Lead Occupational Exposure, Random, Urine

Detecting clinically significant lead exposure due to occupational exposure in random urine specimens This test is not a substitute for blood lead screening.

UNHB - Overview: Hemoglobin Stability, Blood

Work-up of congenital hemolytic anemias

MPLR - Overview: MPL Exon 10 Mutation Detection, Reflex, Varies

Aiding in the distinction between a reactive cytosis and a chronic myeloproliferative disorder Evaluates for mutations in MPL in an algorithmic process for the MPNR / Myeloproliferative Neoplasm, JAK2 V617F with Reflex to CALR and MPL,...

MPNML - Overview: MPL Exon 10 Sequencing, Reflex, Varies

Aiding in the distinction between a reactive cytosis and a myeloproliferative neoplasm when JAK2 V617F testing result is negative Evaluates for variants in MPL in an algorithmic process for MPNCM / Myeloproliferative Neoplasm, CALR with...

QUIN - Overview: Quinidine, Serum

Assessing and adjusting quinidine dosage for optimal therapeutic level Assessing quinidine toxicity

TPI1 - Overview: Triosephosphate Isomerase Enzyme Activity, Blood

Evaluating individuals with chronic nonspherocytic hemolytic anemia Evaluating individuals with early onset neurologic impairment Genetic counseling for families with triosephosphate isomerase deficiency

RUFI - Overview: Rufinamide, Serum

Monitoring serum rufinamide concentrations, assessing compliance, and adjusting dosage in patients receiving other drugs that interact pharmacokinetically with rufinamide (ie, drugs that induce liver CYP3A4 enzymes) and may be helpful in...

WGSDX - Overview: Whole Genome Sequencing for Hereditary Disorders, Varies

Serving as a first-tier test to identify a molecular diagnosis in patients with suspected genetic disorders, which can allow for: -Better understanding of the natural history/prognosis -Targeted management (anticipatory guidance, management...

DOGPF - Overview: Dog Dander, IgE, with Reflex to Dog Dander Components, IgE, Serum

Evaluating patients with suspected dog dander allergy

LPMGF - Overview: Lymphocyte Proliferation to Mitogens, Blood

Assessing T-cell function in patients on immunosuppressive therapy, including solid-organ transplant patients Evaluating patients suspected of having impairment in cellular immunity Evaluation of T-cell function in patients with primary...

LPAGF - Overview: Lymphocyte Proliferation to Antigens, Blood

Assessing T-cell function in patients on immunosuppressive therapy, including solid-organ transplant patients Evaluating patients suspected of having impairment in cellular immunity Evaluation of T-cell function in patients with primary...

QNKS - Overview: Natural Killer (NK)/Natural Killer T-Cell Subsets, Quantitative, Blood

Quantitation of the major natural killer (NK)-cell subsets relative to total NK cells (NK cell subsets) or total lymphocytes (NK T cells) Assessment in the following clinical contexts: HIV, primary immune deficiencies with NK cell...

RPDE - Overview: Rapidly Progressive Dementia Evaluation, Spinal Fluid

Evaluation of individuals presenting with rapidly progressive dementia of uncertain disease etiology and a differential diagnosis of Creutzfeldt-Jakob disease and rapidly progressive Alzheimer disease

TRECS - Overview: T-Cell Receptor Excision Circles Analysis, Blood

Measuring T-cell output or reconstitution (thymopoiesis) following hematopoietic cell transplantation or highly active antiretroviral therapy Evaluating thymic function in patients with cellular or combined inborn errors of immunity...

TCP - Overview: T-Cell Subsets, Naive, Memory, and Activated, Blood

Determining the presence of naive, memory, and activated T cells in various clinical contexts including autoimmune diseases, immunodeficiency states, T-cell recovery post-hematopoietic stem cell transplant, DiGeorge syndrome, and as a...

TIKLB - Overview: Tick-Borne Panel, Molecular Detection, PCR, Blood

Evaluating patients with suspected human monocytic ehrlichiosis, human granulocytic anaplasmosis, babesiosis, or Borrelia miyamotoi infection Evaluating patients with a history of, or suspected, tick exposure who are presenting with...

AVWPR - Overview: von Willebrand Disease Profile, Plasma

Detection of deficiency or abnormality of von Willebrand factor (VWF) and related deficiency of factor VIII coagulant activity Subtyping von Willebrand disease (VWD) as type 1 (most common), type 2 variants (less common), or type 3...

BARTB - Overview: Bartonella, Molecular Detection, PCR, Blood

Aiding in the diagnosis of Bartonella infection when Bartonella DNA would be expected to be present in blood, especially endocarditis

ALKLC - Overview: Anaplastic Lymphoma Kinase for Lung Cancer, Immunohistochemistry

Identification of anaplastic lymphoma kinase overexpression Diagnosis of inflammatory myofibroblastic tumor, anaplastic large-cell lymphoma, and for targeted therapy of lung adenocarcinoma

AMS - Overview: Amylase, Total, Serum

Diagnosis and management of pancreatitis Evaluation of pancreatic function

BRIVA - Overview: Brivaracetam, Plasma

Assessing compliance and toxicity for brivaracetam

CRTFR - Overview: Creatinine, Random, Urine

Normalizing urinary analytes to account for the variation in urinary concentrations between individuals when using random urine collections

DIPGS - Overview: Diphtheria Toxoid IgG Antibody, Serum

Determining a patient's immunological response to diphtheria toxoid vaccination Aiding in the evaluation of immunodeficiency

CULAF - Overview: Culture for Genetic Testing, Amniotic Fluid

Producing amniocyte cultures that can be used for genetic analysis

CK - Overview: Creatine Kinase (CK), Serum

Diagnosing and monitoring myopathies or other trauma, toxin, or drug-induced muscle injury

CEASF - Overview: Carcinoembryonic Antigen (CEA), Spinal Fluid

Detecting meningeal carcinomatosis and intradural or extradural infiltration Differentiating brain parenchymal metastasis from adenocarcinoma or squamous-cell carcinoma

FELBA - Overview: Felbamate (Felbatol), Serum

Determining whether a poor therapeutic response is attributable to noncompliance or lack of drug effectiveness Monitoring changes in serum concentrations resulting from interactions with coadministered drugs such as barbiturates and...

CEA - Overview: Carcinoembryonic Antigen (CEA), Serum

Monitoring colorectal cancer and selected other cancers such as medullary thyroid carcinoma May be useful in assessing the effectiveness of chemotherapy or radiation treatment This test is not useful for screening the general population...

DXPIN - Overview: Doxepin and Nordoxepin, Serum

Monitoring doxepin therapy Evaluating potential doxepin toxicity Evaluating patient compliance

DESPR - Overview: Desipramine, Serum

Monitoring serum concentration of desipramine during therapy Evaluating potential desipramine toxicity May aid in evaluating patient compliance

AFOLR - Overview: Folate Receptor Alpha (FOLR1), Semi-Quantitative Immunohistochemistry, Manual

Diagnosis of epithelial ovarian cancer that may be eligible for treatment with an anti-folate receptor 1 protein antibody

CRETR - Overview: Creatinine, Random, Urine

Normalization of urinary analytes to account for the variation in urinary concentrations between individuals when using random urine collections

CLOBZ - Overview: Clobazam and Metabolite, Serum

Monitoring clobazam therapy

BRUTA - Overview: Brucella Total Antibody Confirmation, Agglutination, Serum

Diagnosis of brucellosis

CRT2F - Overview: Creatinine, 24 Hour, Urine

Normalizing urinary analytes to account for the variation in urinary concentration

CRE2 - Overview: Creatinine, Urine

Normalization of urinary analytes to account for the variation in urinary concentrations between individuals when using random urine collections

F8IS - Overview: Coagulation Factor VIII Inhibitor Screen, Plasma

Detecting the presence of a specific factor inhibitor directed against coagulation factor VIII

EVROL - Overview: Everolimus, Blood

Managing everolimus immunosuppression in solid organ transplant