Test Catalog

Test Id : EOSU1

Eosinophils, Random, Urine

Useful For
Suggests clinical disorders or settings where the test may be helpful

Investigation of possible acute interstitial nephritis

Method Name
A short description of the method used to perform the test

Hansel Stain

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

Eosinophils, U

Lists additional common names for a test, as an aid in searching


Specimen Type
Describes the specimen type validated for testing


Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Container/Tube: Unstained cytospin slide

Specimen Volume: 1 slide

Collection Instructions:

1. Collect a random urine specimen.

2. Centrifuge 10 mL of a random urine collection.

3. Pour off supernatant. Assess urine sediment for presence of white blood cells (WBC). If no WBC are seen, the eosinophil test cannot be performed. If WBC are present, prepare slides using the centrifuged sediment.

4. The unstained slide should be prepared within 2 hours of collection. Only an unstained slide will be accepted. Any other specimen, including the raw urine specimen, will be rejected.

5. Centrifuge urine in cytospin centrifuge at speed of 750 rpm for 5 minutes.

6. Slides need to be labeled with 2 full patient identifiers.

7. Guidelines for slide preparation. Use the sediment to prepare slides as follows:

a. 150 mcL of sample for 1 to 3 WBC/high power field (hpf)

b. 100 mcL of sample for moderate to normal sediment (<50 cell/hpf)

c. 50 mcL of sample for heavier sediment (>50 cells/hpf)

d. 25 mcL for packed fields of sediment


If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.

Specimen Minimum Volume
Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

See Specimen Required

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

Stained slides

Urine aliquots

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
Urine Ambient (preferred) 14 days SLIDE
Frozen 14 days SLIDE
Refrigerated 14 days SLIDE

Useful For
Suggests clinical disorders or settings where the test may be helpful

Investigation of possible acute interstitial nephritis

Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Eosinophils are white blood cells that normally do not appear in urine. The presence of eosinophils in the urine is seen in acute interstitial nephritis, which is caused by an allergic reaction, typically to drugs.

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.


Provides information to assist in interpretation of the test results

Results of greater than 5% eosinophils are indicative of acute interstitial nephritis; results between 1% and 5% eosinophils are indeterminant.

Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

No significant cautionary statements

Clinical Reference
Recommendations for in-depth reading of a clinical nature

1.Hansel FK: In: Clinical Allergy. CV Mosby Company; 1953

2. Brunzel NA: Microscopic examination of urine sediment. In: Fundamentals of Urine and Body Fluid Analysis. 4th ed. Saunders; 2017:141

3. Muriithi AK, Leung N, Valeri AM, et al:. Biopsy-proven acute interstitial nephritis, 1993-2011: a case series. Am J Kidney Dis. 2014 Oct;64(4):558-566. doi: 10.1053/j.ajkd.2014.04.027

Method Description
Describes how the test is performed and provides a method-specific reference

Hansel stain.(Brunzel NA, ed: Microscopic examination of urine sediment. In: Fundamentals of Urine and Body Fluids Analysis. 3rd ed. Elsevier; 2012:171-172)

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information


Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Sunday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

Same day/1 day

Specimen Retention Time
Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

Urine: 2 days; Slide: 7 days

Performing Laboratory Location
Indicates the location of the laboratory that performs the test


Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their Regional Manager. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.


LOINC® Information
Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.

Test Id Test Order Name Order LOINC Value
EOSU1 Eosinophils, U 32014-3
Result Id Test Result Name Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
EOSU1 Eosinophils, U 32014-3

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports

Test Update Resources

Change Type Effective Date
Test Changes - Specimen Information 2022-08-16