HPS12 - Overview: HIV-1/HIV-2 RNA Detection Prenatal, Serum

Diagnosis of HIV-1 and/or HIV-2 infection in pregnant individuals with indeterminate or inconclusive HIV serologic test results Diagnosis of HIV-1 and/or HIV-2 infection in pregnant individuals in the acute or early phase of HIV-1 and/or...

HBIM - Overview: Hepatitis B Virus Core IgM Antibody, Serum

Diagnosis of acute hepatitis B virus (HBV) infection Identifying acute HBV infection in the serologic window period when HBV surface antigen and HBV surface antibody results are negative Differentiation between acute, chronic, or past...

HVA - Overview: Homovanillic Acid, 24 Hour, Urine

Screening children for catecholamine-secreting tumors using a 24-hour urine collection when requesting homovanillic acid only Monitoring neuroblastoma treatment Screening patients with possible inborn errors of catecholamine metabolism

MMPGM - Overview: Mumps Virus Antibody, IgM and IgG, Serum

Diagnosis of mumps virus infection Determination of postimmunization immune response of individuals to the mumps vaccine Documentation of previous infection with mumps virus in an individual with no previous record of immunization to...

NTRK - Overview: NTRK Gene Fusion Panel, Tumor

Identifying solid tumors that may respond to targeted therapies by simultaneously assessing for fusions involving targeted regions of the NTRK1, NTRK2, and NTRK3 genes resulting in fusion transcripts. This test is not useful for...

NSESF - Overview: Neuron-Specific Enolase (NSE), Spinal Fluid

An auxiliary test in the diagnosis of Creutzfeldt-Jakob disease An auxiliary test in the diagnosis of small cell lung carcinoma metastasis to central nervous system or leptomeninges

NMHR - Overview: N-Methylhistamine, Random, Urine

Screening for and monitoring of mastocytosis and disorders of systemic mast-cell activation, such as anaphylaxis and other forms of severe systemic allergic reactions using random urine specimens Monitoring therapeutic progress in...

OAPNS - Overview: Ova and Parasite, Microscopy, Varies

Detecting and identifying parasitic protozoa and eggs and larvae of parasitic helminths

ANIDE - Overview: Organism Referred for Identification, Anaerobic Bacteria

Identifying anaerobic bacteria involved in human infections

PYRC - Overview: Pyruvate, Spinal Fluid

Investigating possible disorders of mitochondrial metabolism, when used in conjunction with cerebrospinal fluid lactate, collected at the same time, to determine the lactate-to-pyruvate (L:P) ratio Evaluating patients with neurologic...

PMND1 - Overview: Primary Membranous Nephropathy Diagnostic Cascade, Serum

Distinguishing primary from secondary membranous nephropathy using an algorithmic approach Monitoring patients with membranous nephropathy at very low antibody titers Screening for anti-phospholipase A2 receptor antibodies

MTDNX - Overview: Methadone Confirmation, Chain of Custody, Random, Urine

Monitoring for compliance of methadone treatment for analgesia or drug rehabilitation Assessing compliance with rehabilitation programs Chain of custody is required whenever the results of testing could be used in a court of law. Its...

PSAU - Overview: Prostate-Specific Antigen (PSA) Ultrasensitive, Serum

As an aid in the detection of prostate cancer when used in conjunction with a digital rectal exam in men ages 50 years and older To aid in the prognosis and management of individuals diagnosed with prostate cancer Monitoring disease after...

PAI1 - Overview: Plasminogen Activator Inhibitor Antigen, Plasma

Identification of heredity elevation or deficiency of plasminogen activator inhibitor type 1 Determination of risk for veno-occlusive disease associated with bone marrow transplantation Differential diagnosis of impaired fibrinolysis...

PYR - Overview: Pyruvic Acid, Blood

Screening for possible disorders of mitochondrial metabolism, when used in conjunction with blood lactate collected at the same time, to determine the lactate-to-pyruvate ratio

PR3 - Overview: Proteinase 3 Antibodies, IgG, Serum

Evaluating patients with clinical features of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, specifically granulomatosis with polyangiitis (GPA), microscopic polyangiitis, and eosinophilic granulomatosis with...

PTTP - Overview: Prothrombin Time, Plasma

Screening assay to detect deficiencies of one or more coagulation factors (factors I, II, V, VII, X) Screening assay to detect coagulation inhibition Monitoring intensity of oral anticoagulant therapy when combined with INR reporting

PTHFN - Overview: Parathyroid Hormone, Fine-Needle Aspiration Biopsy (FNAB)-Needle Wash

Discriminating thyroid tissue from enlarged parathyroid glands Facilitating parathyroid localization prior to surgery An adjunct to cytology examination of fine-needle aspiration specimens to confirm or exclude presence of parathyroid...

PDBS - Overview: Pompe Disease, Blood Spot

Evaluating patients with a clinical presentation suggestive of Pompe disease (muscle hypotonia, weakness, or cardiomyopathy) outside of the newborn screening setting

TFEBF - Overview: Renal Cell Carcinoma, 6p21.1 (TFEB) Rearrangement, FISH, Tissue

Identifying TFEB gene rearrangements in patients with renal cell carcinoma (RCC)

MAL - Overview: Rapid Malaria/Babesia Smear, Varies

Rapid and accurate detection and species identification of Plasmodium Detection of Babesia, trypanosomes, and some species of microfilariae

RIB - Overview: Ribosome P Antibodies, IgG, Serum

As an adjunct in the diagnostic evaluation of patients with systemic lupus erythematosus (SLE) May be useful in the phenotypic stratification of SLE patients at risk for neuropsychiatric SLE, lupus nephritis and/or hepatitis

PRA - Overview: Renin Activity, Plasma

Investigation of primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter...

POWVU - Overview: Powassan Virus, RNA, Molecular Detection, PCR, Random, Urine

Rapid testing for Powassan virus RNA (lineage 1 and lineage 2) using random urine specimens An adjunctive test to serology for detection of early Powassan virus infection (ie, first few days after symptom onset). This assay should not...

POWVC - Overview: Powassan Virus, RNA, Molecular Detection, PCR, Spinal Fluid

Rapid testing for Powassan virus RNA (lineage 1 and lineage 2) using cerebrospinal fluid specimens An adjunctive test to serology for detection of early Powassan virus infection (ie, first few days after symptom onset) This assay should...

PKUSC - Overview: Phenylalanine and Tyrosine, Self-Collect, Blood Spot

Monitoring effectiveness of therapy in patients with hyperphenylalaninemia in a patient-collected specimen This test is not sufficient for follow-up for abnormal newborn screening results or for establishing a diagnosis of a specific...

POWVB - Overview: Powassan Virus, RNA, Molecular Detection, PCR, Blood

Rapid testing for Powassan virus RNA (lineage 1 and lineage 2) using whole blood specimens An adjunctive test to serology for detection of early Powassan virus infection (ie, first few days after symptom onset) This assay should not be...

PBALP - Overview: Porphobilinogen and Aminolevulinic Acid, Plasma

An equivalent option to urine for first-line test for evaluation of a suspected acute porphyria Monitoring patients undergoing treatment for an acute intermittent porphyria or other acute porphyria

PPFWE - Overview: Protoporphyrins, Fractionation, Washed Erythrocytes

Preferred test for analysis of erythrocyte protoporphyrin fractions Preferred test for evaluating patients with possible diagnoses of erythropoietic protoporphyria and X-linked dominant protoporphyria Establishing a biochemical...

PBGDW - Overview: Porphobilinogen Deaminase, Washed Erythrocytes

Confirmation of a diagnosis of acute intermittent porphyria using washed erythrocyte specimens

PREGN - Overview: Pregnenolone, Serum

An ancillary test for congenital adrenal hyperplasia, particularly in situations in which a diagnosis of both 21- and 11-hydroxylase deficiency have been ruled out Confirming a diagnosis of 3-beta-hydroxy dehydrogenase deficiency

PARVO - Overview: Parvovirus B19, Molecular Detection, PCR, Varies

Diagnosing parvovirus B19 infection

RO52 - Overview: Ro52 Antibody, IgG, Serum

Evaluating patients at risk for connective tissue disease with or without interstitial lung disease Differentiating single vs double positivity for Ro52 and Ro60 antibodies in combination with anti-Ro60

RO60 - Overview: Ro60 Antibody, IgG, Serum

Evaluating patients at risk for connective tissue disease with or without interstitial lung disease Differentiating single vs double positivity for Ro52 and Ro60 antibodies in combination with anti-Ro60

ROPAN - Overview: Ro52 and Ro60 Antibodies, IgG, Serum

Evaluating patients at risk for connective tissue disease with or without interstitial lung disease Differentiation of antibodies to Ro52 and Ro60 in patients known to be positive for anti-SS-A (Ro) antibodies

RISAP - Overview: Risankizumab Quantitation with Antibodies, Serum

Evaluation of patients with limited primary (initial) response to or secondary loss of response to risankizumab

DBS1 - Overview: Diabetes Mellitus Type 1 Evaluation, Serum

Distinguishing type 1 from type 2 diabetes mellitus Identifying individuals at risk of type 1 diabetes (including high-risk relatives of patients with diabetes) Predicting future insulin requirement treatment in patients with adult-onset...

CRITH - Overview: DNA Double-Stranded (dsDNA) Antibodies by Crithidia luciliae IFA, IgG, Serum

Confirmation testing for dsDNA IgG antibodies in patients with clinical features of systemic lupus erythematosus or at-risk for disease This test should not be used independently for monitoring treatment response or establishing...

DENGC - Overview: Dengue Virus, Molecular Detection, PCR, Spinal Fluid

Aiding in the diagnosis of central nervous system infection caused by dengue virus

DENGS - Overview: Dengue Virus, Molecular Detection, PCR, Serum

Aiding in the diagnosis of acute infection caused by dengue virus

DSM5X - Overview: Drugs of Abuse Screen 5, Chain of Custody, Meconium

Identifying amphetamines (and methamphetamines), opiates, and phencyclidine, as well as metabolites of cocaine and marijuana in meconium specimens Chain of custody is required whenever the results of testing could be used in a court of...

DSM4X - Overview: Drugs of Abuse Screen 4, Chain of Custody, Meconium

Identifying amphetamines (and methamphetamines) and opiates, as well as metabolites of cocaine and marijuana in meconium specimen Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is...

DDITT - Overview: D-Dimer, Plasma

Excluding the diagnosis of acute pulmonary embolism or deep vein thrombosis, particularly when results of a sensitive D-dimer assay are combined with clinical information, including pretest disease probability(1-4) Diagnosis of...

E157C - Overview: Escherichia coli O157:H7 Culture, Feces

Determining whether Escherichia coli O157:H7 may be the cause of diarrhea Reflexive testing for Shiga toxin and/or E coli O157:H7 nucleic acid amplification test-positive feces This test is generally not useful for patients hospitalized...

C341Q - Overview: Complement C3 and C4 with Anti-C1q Antibodies, Serum

Evaluating patients with suspected anti-C1q vasculitis Predicting renal involvement in patients with systemic lupus erythematosus

CRANR - Overview: Cortisol, Free, Random, Urine

Investigating suspected hypercortisolism when a 24-hour collection is prohibitive (ie, pediatric patients)

CHLAP - Overview: Chlamydia IgM and IgG Panel, Immunofluorescence, Serum

Aiding in the clinical diagnosis of Chlamydia pneumoniae or Chlamydia psittaci infection

CMVQN - Overview: Cytomegalovirus (CMV) DNA Detection and Quantification by Real-Time PCR, Plasma

Detection and quantification of cytomegalovirus (CMV) viremia Monitoring CMV disease progression and response to antiviral therapy

CHF8 - Overview: Chromogenic Factor VIII Activity Assay, Plasma

Monitoring coagulation factor replacement therapy of selected extended half-life coagulation factor replacements Aiding in the diagnosis of hemophilia A using a 2-stage assay, especially when the 1-stage assay result was normal

CTXBS - Overview: Cerebrotendinous Xanthomatosis, Blood Spot

Evaluating patients with a clinical suspicion of cerebrotendinous xanthomatosis (CTX) using dried blood spot specimens Monitoring individuals with CTX on chenodeoxycholic acid (CDCA) therapy This test is not useful for the...