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VLCZ - Overview: Very Long Chain Acyl-CoA Dehydrogenase Deficiency, Full Gene Analysis, Varies

Confirmation of a diagnosis of very long chain acyl-CoA dehydrogenase (VLCAD) deficiency Carrier screening in cases where there is a family history of VLCAD deficiency, but an affected individual is not available for testing or...

A1APP - Overview: Alpha-1-Antitrypsin Phenotype, Serum

Identification of homozygous and heterozygous phenotypes of the alpha-1-antitrypsin deficiency

AMBF - Overview: Amylase, Body Fluid

Evaluation of patients with a pathological accumulation of fluid to determine whether pancreatic inflammation, pancreatic fistula, or esophageal rupture may be contributing Aiding in the diagnosis of pancreatitis

ACMFS - Overview: Acetylcholine Receptor Modulating Antibody, Flow Cytometry Assay, Serum

Diagnosis for autoimmune myasthenia gravis (MG) in adults and children Distinguishing autoimmune from congenital MG in adults and children or other acquired forms of neuromuscular junction transmission disorders. This test is a...

AMPMX - Overview: Amphetamine-Type Stimulants Confirmation, Chain of Custody, Meconium

Detecting in utero drug exposure up to 5 months before birth Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen by...

GUSBW - Overview: Beta-Glucuronidase, Leukocytes

Supporting the biochemical diagnosis of mucopolysaccharidosis type VII (MPS VII, Sly syndrome) in whole blood This test is not useful for carrier detection.

DRPL - Overview: Dentatorubral-Pallidoluysian Atrophy (DRPLA) Gene Analysis, Varies

Confirming the diagnosis of dentatorubral-pallidoluysian atrophy (DRPLA) for symptomatic patients Predictive testing for individuals with a family history of DRPLA and a documented expansion in the ATN1 gene in an affected family member

F2ISO - Overview: F2-Isoprostanes, Random, Urine

Assessment of in vivo lipid peroxidation Considered to be an index of systemic oxidative stress over time

FMBNY - Overview: Fetomaternal Bleed, New York, Blood

Determining the volume of fetal-to-maternal hemorrhage for the purposes of recommending an increased dose of the Rh immune globulin This test is used only for specimens collected in New York state.

DIMER - Overview: D-Dimer, Plasma

Diagnosis of intravascular coagulation and fibrinolysis, also known as disseminated intravascular coagulation, especially when combined with clinical information and other laboratory test data (eg, platelet count, assays of clottable...

FMB - Overview: Fetomaternal Bleed, Flow Cytometry, Blood

Determining the volume of fetal-to-maternal hemorrhage for the purposes of recommending an increased dose of the Rh immune globulin

CARF - Overview: Carbamazepine, Free, Serum

Monitoring unbound or free carbamazepine levels in patients where the total carbamazepine result is within the therapeutic range, but the patient is experiencing side effects Monitoring carbamazepine (free) therapy in patients who are...

BIOTS - Overview: Biotinidase, Serum

Preferred test for the diagnosis of biotinidase deficiency Follow-up testing for certain organic acidurias

CIFS - Overview: Cutaneous Immunofluorescence Antibodies, IgG and IgG4, Serum

Confirming the presence of IgG and/or IgG4 antibodies to diagnose pemphigoid, pemphigus, epidermolysis bullosa acquisita, or bullous lupus erythematosus

B2M - Overview: Beta-2-Microglobulin, Serum

Prognosis assessment of multiple myeloma Evaluation of renal tubular disorders

ECULI - Overview: Eculizumab, Serum

Assessing the response to eculizumab therapy Assessing the need for dose escalation Evaluating the potential for dose de-escalation or discontinuation of therapy in remission states Monitoring patients who need to be above a certain...

SLEG - Overview: Legionella pneumophila (Legionnaires Disease), Antibody, Serum

Evaluating possible legionellosis (Legionnaires disease, Pontiac fever, extrapulmonary legionella infection caused by Legionella pneumophila)

HIBAG - Overview: Histoplasma and Blastomyces Antigen, Enzyme Immunoassay, Serum

Diagnosing Histoplasma capsulatum or Blastomyces dermatitidis infection, without differentiation between the organisms, using serum specimens Monitor antigen levels following initiation of antifungal treatment

INSFT - Overview: Insulin, Free and Total, Serum

Assessing free (bioactive) insulin concentrations in patients with known or suspected anti-insulin antibodies

GDS - Overview: Gadolinium, Serum

Aiding in documenting previous exposure to gadolinium-based contrast agents using serum specimens

QFEVR - Overview: Q Fever Antibody Screen with Titer Reflex, Serum

Screening for exposure to Coxiella burnetii, the causative agent of Q fever This test should not be used as a screening procedure for the general population.

FRAG - Overview: Osmotic Fragility, Erythrocytes

Evaluating suspected hereditary spherocytosis-associated hemolytic anemia Confirming or detecting mild spherocytosis

PK1 - Overview: Pyruvate Kinase Enzyme Activity, Blood

Evaluation of nonspherocytic hemolytic anemia Evaluation of neonatal anemia or jaundice Evaluation of unexplained noninfectious hepatic failure Evaluation of unexplained iron overload Evaluation of unusually severe hemoglobin S...

PKC - Overview: Pyruvate Kinase Enzyme Activity, Blood

Evaluation of nonspherocytic hemolytic anemia as a part of a profile Evaluation of neonatal anemia or jaundice Evaluation of unexplained noninfectious hepatic failure Evaluation of unexplained iron overload Evaluation of unusually...

PSGN - Overview: Plasminogen Activity, Plasma

Evaluating patients with ligneous conjunctivitis (strong association with homozygous plasminogen deficiency) Evaluating fibrinolysis, in combination with other components of the fibrinolytic system (fibrinogen, tissue...

PLHBB - Overview: Plasma Free Hemoglobin, Plasma

Determining whether hemolysis is occurring such as from: -Transfusion reaction -Mechanical fragmentation of red blood cells -Relative comparison to baseline levels in extracorporeal membrane oxygenation and centrifugal ventricular assist...

PNP - Overview: Platelet Neutralization Procedure, Plasma

Aiding in the confirmation or exclusion of the presence of a lupus anticoagulant (LAC) inhibitor when used in conjunction with other appropriate coagulation tests. Aids in differentiating deficiencies or inhibitors of specific coagulation...

TTSC - Overview: Thrombin Time (Bovine), Plasma

Detecting or excluding the presence of heparin or heparin-like anticoagulants (which act by enhancing antithrombin's inhibition of thrombin and other procoagulant enzymes) when used in conjunction with the reptilase time (RT) in evaluating...

TTIGS - Overview: Tetanus Toxoid IgG Antibody, Serum

Assessing antibody response to the tetanus toxoid vaccine, which should be performed at least 3 weeks after immunization Aiding in the evaluation of immunodeficiency This test should not be used to diagnose tetanus infection.

THCMX - Overview: 11-nor-Delta-9-Tetrahydrocannabinol-9-Carboxylic Acid (Carboxy-THC) Confirmation, Chain of Custody, Meconium

Detecting in utero drug exposure to marijuana (tetrahydrocannabinol) up to 5 months before birth Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the...

VIBC - Overview: Vibrio Culture, Feces

Determining whether Vibrio species may be the cause of diarrhea This test is generally not useful for patients that have been hospitalized for more than 3 days because the yield from these patients' specimens is very low, as is the...

APMSC - Overview: Activated Partial Thromboplastin Time (APTT) Mix 1:1, Plasma

Screening for certain coagulation factor deficiencies and abnormalities (eg, factor VIII, IX, XI, or XII). Detection of coagulation inhibitors such as lupus anticoagulant, antiphospholipid antibodies, specific factor inhibitors, and...

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Primary ciliary dyskinesia - Insights

Learn more about Mayo Clinic Laboratories’ robust approach to testing for primary ciliary dyskinesia, a rare genetic condition that can lead to chronic otosinopulmonary disease and infertility in men....

https://www.mayocliniclabs.com/it-mmfiles/cpt-code-changes.xlsx

note, CPT Code changes listed on this document are effective January 1st, 2025.*** ***Updates and other changes may occur, and be reflected on this document, leading up to 2025*** ***CPT Code Updates...

CPT Codes and LOINC Update: September 2019 - Insights

View a full list of new CPT codes, Test Classification Updates, LOINC Codes, and Z-Codes posted to mayocliniclabs.com during the month of September 2019....

MCL Primary Ciliary Dyskinesia Genetic Testing Patient Information MC1235297

MCL Primary Ciliary Dyskinesia Genetic Testing Patient Information Complete print Reset Form Primary Ciliary Dyskinesia Genetic Testing Patient Information Instructions Accurate interpretation reporting...

New communication process for CPT Code changes - Insights

Mayo Clinic Laboratories (MCL) is pleased to announce an essential update to our CPT code communication process and website layout. This change is designed to bring timely notifications for accurate billing...