ZNU - Overview: Zinc, 24 Hour, Urine
Identifying the cause of abnormal serum zinc concentrations using 24-hour urine specimens
VEGF - Overview: Vascular Endothelial Growth Factor, Plasma
Evaluation of patients with suspected POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome, particularly in differentiating from other forms of polyneuropathy and/or monoclonal plasma cell...
VITB3 - Overview: Vitamin B3 and Metabolites, Plasma
Assisting in the diagnosis of suspected vitamin B3 deficiency or toxicity May be useful in determining response to therapy
APHTC - Overview: Amphiphysin Antibody Titer Assay, Spinal Fluid
Evaluating patients with recent onset of a subacute neurological disorder for which a paraneoplastic basis might be suspected, particularly if the patient has a previous history, risk factors, or family history of cancer, especially lung or...
GRAS3 - Overview: Grass Panel # 3, Serum
Establishing a diagnosis of an allergy to cultivated rye, rye, sweet vernal, timothy, and velvet leaf Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or...
RHUT - Overview: Rheumatoid Factor, Serum
Diagnosis and prognosis of rheumatoid arthritis
CSPCF - Overview: Plasma Cell Proliferative Disorder, Pre-Analysis Cell Sorting, Bone Marrow
Aiding in the diagnosis of new cases of multiple myeloma or other plasma cell proliferative disorders Sorting plasma cells for fluorescence in situ hybridization analysis
PRAME - Overview: PRAME Immunostain, Technical Component Only
Differentiation between melanoma and benign nevi.
CIFA - Overview: Cutaneous Immunofluorescence Antibodies, IgA, Serum
Confirming the presence of IgA antibodies to diagnose pemphigoid, pemphigus, epidermolysis bullosa acquisita, or bullous lupus erythematosus
MHPRP - Overview: Metamycoplasma hominis, Molecular Detection, PCR, Plasma
Rapid, sensitive, and specific identification of Metamycoplasma hominis from plasma This test is not intended for medicolegal use.
THCG - Overview: Human Chorionic Gonadotropin (hCG), Quantitative, Pregnancy, Serum
Early detection of pregnancy Investigation of suspected ectopic pregnancy or other pregnancy-related complications Monitoring in vitro fertilization patients This test is not useful for detecting or monitoring tumors or gestational...
HMGA - Overview: High Mobility Group A2 (HMGA2) Immunostain, Technical Component Only
Identification of abnormal expression of the high mobility group protein, HMGA2
HE4 - Overview: Human Epididymis Protein 4, Serum
Aiding in monitoring patients with treated epithelial ovarian cancer for recurrence or progression This test should not be used as a screening test for ovarian cancer.
HER2I - Overview: HER2 Immunostain, Technical Component Only
Qualitative detection of HER2 protein overexpression in a diagnostic setting in formalin-fixed paraffin-embedded tissue sections
LGBWB - Overview: Globotriaosylsphingosine, Blood
Screening of patients with Fabry disease when a serum specimen is not available This test should not be used for newborn screening followup.
HCQ - Overview: Hydroxychloroquine, Serum
Monitoring serum hydroxychloroquine concentrations, assessing compliance, and adjusting dosage in patients
GRAS2 - Overview: Grass Panel # 2, Serum
Establishing a diagnosis of an allergy to Bahia, Bermuda, Johnson, June/Kentucky blue, rye, and timothy Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or...
FOOD6 - Overview: Food Panel, Serum
Establishing a diagnosis of an allergy to codfish, cow's milk, egg white, peanut, soybean, and wheat Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or...
FOOD7 - Overview: Food-Seafood Panel, Serum
Establishing a diagnosis of an allergy to mussel, codfish, salmon, shrimp, and tuna Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic...
FOOD4 - Overview: Food-Grain Panel, Serum
Establishing a diagnosis of an allergy to barley, rice, rye, and wheat Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm...
FOOD2 - Overview: Food-Fruit Panel, Serum
Establishing a diagnosis of an allergy to apple, banana, peach, and pear Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To...
FOOD1 - Overview: Food-Nut Panel # 2, Serum
Establishing a diagnosis of an allergy to cashew, pecan, pistachio, and walnut Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To...
FENR - Overview: Fentanyl Screen with Reflex, Random, Urine
Screening for drug abuse or use involving fentanyl and confirmation of fentanyl if present in the screen
FETH2 - Overview: Feather Panel # 2, Serum
Establishing a diagnosis of an allergy to chicken, duck, goose, and turkey Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To...
UE3 - Overview: Estriol, Unconjugated, Serum
As an adjunct biomarker in the prenatal diagnosis of disorders of fetal steroid metabolism, including Smith-Lemli-Opitz syndrome (1,2) and X-linked ichthyosis (placental sulfatase deficiency disorders) Evaluating primary or secondary fetal...
FDP1 - Overview: Food Panel #2, Serum
Establishing a diagnosis of an allergy to cabbage, paprika, spinach, and tomato Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To...
KRT34 - Overview: Keratin (34BE12) Immunostain, Technical Component Only
Identification of cells expressing high-molecular-weight cytokeratin
ASYNC - Overview: Alpha-Synuclein Protein Aggregates, Spinal Fluid
Detection of pathogenic alpha-synuclein (alpha-synuclein aggregates) in adult patients being assessed for clinically uncertain cognitive decline or clinically uncertain parkinsonian syndromes
ALCU - Overview: Aluminum/Creatinine Ratio, Urine
Measurement of aluminum concentration as a part of assessing for aluminum exposure
ASO - Overview: Antistrep-O Titer, Serum
Demonstration of acute or recent streptococcal infection
MSUSC - Overview: Branched-Chain Amino Acids, Self-Collect, Blood Spot
Monitoring patients with maple syrup urine disease using specimens collected at home
CD200 - Overview: CD200 (OX2) Immunostain, Technical Component Only
Identifying the presence of CD200 (OX2) protein within chronic lymphocytic leukemia, small lymphocytic lymphoma, hairy cell leukemia, and primary mediastinal large B-cell lymphoma
MT - Overview: Metallothionein Immunostain, Technical Component Only
Supporting the diagnosis of Wilson disease
PNYA - Overview: Phenytoin, Total, Serum
Monitoring for appropriate therapeutic concentration Assessing compliance or toxicity
MEF2B - Overview: Myocyte Enhancer Factor 2 (MEF2B) Immunostain, Technical Component Only
Lymphoma classification
SABP - Overview: Streptococcal Antibodies Profile, Serum
Demonstration of acute or recent streptococcal infection using both antistreptolysin O and anti-DNase B titers
PIK3B - Overview: Cell-Free DNA PIK3CA Test, Blood
Identification of hormone receptor positive and human epidermal growth factor receptor 2 negative (HR+/HER2-) advanced breast cancer tumors that may be eligible for treatment with targeted kinase inhibitor therapy (eg, alpelisib).
ULFA - Overview: Cryptococcus Antigen Screen, Lateral Flow Assay, Random, Urine
Aiding in the diagnosis of infection with Cryptococcus neoformans or Cryptococcus gattii This test should not be used as a test of cure. This test should not be used as a screening procedure for the general population.
LDPU - Overview: Limited Drug Profile, 3 Drug Classes, Immunoassay, Random, Urine
Detecting drug use involving barbiturates, cocaine, and carboxy-tetrahydrocannabinol This test is not intended for use in employment-related testing.
C1ES - Overview: C1 Esterase Inhibitor Antigen, Serum
Diagnosis of hereditary angioedema Monitoring levels of C1 esterase inhibitor in response to therapy
SGSU - Overview: Synthetic Glucocorticoid Screen, Random, Urine
Confirming the presence of the listed synthetic glucocorticoids Confirming the cause of secondary adrenal insufficiency
APHTS - Overview: Amphiphysin Antibody Titer Assay, Serum
Evaluating patients with recent onset of a subacute neurological disorder for which a paraneoplastic basis might be suspected, particularly if the patient has a previous history, risk factors, or family history of cancer, especially lung or...
MYCOG - Overview: Mycoplasma pneumoniae Antibodies, IgG, Serum
Screening for IgG antibodies in the indication of recent or past exposure to Mycoplasma pneumoniae
EIACD - Overview: Clostridioides difficile Toxin, EIA, Feces
Diagnosing the presence of toxigenic Clostridioides difficile
FRAG - Overview: Osmotic Fragility, Erythrocytes
Evaluating suspected hereditary spherocytosis-associated hemolytic anemia Confirming or detecting mild spherocytosis
FCDU3 - Overview: Acetyl Fentanyl, Umbilical Cord Tissue
Acetyl Fentanyl, Umbilical Cord Tissue
SCIDP - Overview: Severe Combined Immunodeficiency (SCID) Gene Panel, Varies
Establishing a diagnosis of a severe combined immunodeficiency (SCID) associated with known causal genes Identifying variants within genes known to be associated with SCID, allowing for predictive testing of at-risk family members and/or...
PQNU - Overview: Porphyrins, Quantitative, 24 Hour, Urine
Preferred screening test for congenital erythropoietic porphyria and porphyria cutanea tarda and during symptomatic periods for acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria when specimen transport will be...
HMUOE - Overview: Heavy Metal Occupational Exposure, with Reflex, Random, Urine
Preferred screening test for detection of arsenic, cadmium, mercury, and lead due to occupational exposure using random urine specimens
HMUCR - Overview: Heavy Metal/Creatinine Ratio, with Reflex, Random, Urine
Preferred screening test for detection of arsenic, cadmium, mercury, and lead in random urine specimens
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....
Week in Review: November 1 - Insights
Top highlights include: Facebook launches into the digital space of healthcare, medical breakthrough for Ebola, and how the brain makes memories.