KM55 - Overview: Galactose Deficient IgA1 (KM55) Immunostain, Technical Component Only
Identification of Galactose deficient IgA1 by KM55, useful in the diagnosis of IgA nephropathy
EMAI - Overview: Epithelial Membrane Antigen (EMA) Immunostain, Technical Component Only
Recognizing epithelial derivation of poorly differentiated malignant tumors Subtyping intraductal papillary mucinous neoplasms when used in conjunction with mucin (MUC) 2, MUC5AC and MUC6
ECADB - Overview: E-Cadherin Immunostain, Bone Marrow, Technical Component Only
Differentiation between lobular and ductal neoplasms of the breast
EBV - Overview: Epstein-Barr Virus (EBV) In Situ Hybridization, Technical Component Only
Detection of Epstein-Barr virus (EBV)-encoded RNA in the diagnosis of EBV-associated conditions
ETGSR - Overview: Ethyl Glucuronide Screen with Reflex, Random, Urine
Screening for drug abuse involving alcohol
LEPDT - Overview: Leptospira, IgM, Serum
Aiding in the diagnosis of leptospirosis This test is not useful for establishing cure or response to therapy.
ICOSI - Overview: ICOS (CD278), Immunostain, Technical Component Only
Classification of T-cell lymphomas
IGGI - Overview: IgG Immunostain, Technical Component Only
Classification of lymphomas and multiple myeloma
IGDI - Overview: IgD Immunostain, Technical Component Only
Aids in the classification of lymphomas and multiple myeloma
IGG4I - Overview: IgG4 Immunostain, Technical Component Only
Identification of IgG4-positive plasma cells in the tissue of patients with systemic autoimmune or allergic manifestations
KKBRP - Overview: Kingella kingae, Molecular Detection, PCR, Blood
Aiding in the diagnosis of Kingella kingae infection using whole blood specimens
INSUL - Overview: Insulin Immunostain, Technical Component Only
Identification of normal pancreatic islet beta cells and insulin secreting islet cell tumors
MMAU - Overview: Methylmalonic Acid, Quantitative, Urine
Evaluating children with signs and symptoms of methylmalonic acidemia using urine specimens Evaluating individuals with signs and symptoms associated with a variety of causes of vitamin B12 (cobalamin) deficiency
MMAS - Overview: Methylmalonic Acid, Quantitative, Serum
Evaluating children with signs and symptoms of methylmalonic acidemia using serum specimens Evaluating individuals with signs and symptoms associated with a variety of causes of vitamin B12 (cobalamin) deficiency
ABCRS - Overview: Alpha/Beta Crystallin IHC, Technical Component Only
Characterization of neuroectodermal tumors
ABTIR - Overview: Antibody Titer, Blood and Serum
Monitoring antibody levels during pregnancy to help assess the risk of hemolytic disease of the newborn This test is not useful for monitoring the efficacy of Rh-immune globulin administration.
CARBG - Overview: Carbamazepine-10,11-Epoxide, Serum
Monitoring patients exhibiting symptoms of carbamazepine toxicity whose total serum carbamazepine concentration is within the therapeutic range, but who may be producing significant levels of the active metabolite epoxide, which can...
CALRC - Overview: Calreticulin ex9mut Immunostain, Technical Component Only
Identifying the presence of CALR exon 9 frameshift alterations in myeloproliferative neoplasms
CD56 - Overview: CD56 Immunostain, Technical Component Only
Aiding in the identification of tumors with neuroendocrine differentiation Aiding in the identification of natural killer cell lineage in a subset of lymphomas
CD71 - Overview: CD71 Immunostain, Technical Component Only
Assessment of erythroid lineage
CD38 - Overview: CD38 Immunostain, Technical Component Only
Classification of lymphoproliferative and plasma cell proliferative disorders
CD25 - Overview: CD25 Immunostain, Technical Component Only
Classification of lymphomas
CD34I - Overview: CD34 Immunostain, Technical Component Only
A marker of immaturity in the setting of acute myeloid leukemia or B-cell lymphoblastic leukemia Diagnosis of gastrointestinal stromal tumors, solitary fibrous tumors, and angiosarcomas
MNS - Overview: Manganese, Serum
Monitoring manganese exposure using serum specimens Nutritional monitoring
NUT - Overview: NUT Immunostain, Technical Component Only
Aiding in the diagnosis of nuclear protein in testis midline carcinoma
PRMB - Overview: Primidone and Phenobarbital, Serum
Assessing compliance Monitoring for appropriate therapeutic levels of primidone and phenobarbital Assessing toxicity
S100 - Overview: S-100 Immunostain, Technical Component Only
Aids in the identification of various neoplasms
MNRCU - Overview: Manganese/Creatinine Ratio, Random, Urine
Monitoring manganese exposure using random urine specimens Nutritional monitoring Clinical trials
MCRPL - Overview: Macroprolactin, Serum
Determining biologically active levels of prolactin, in asymptomatic patients with elevated prolactin levels Ruling out the presence of macroprolactin
MTBS - Overview: Microsporidia Stain, Varies
Diagnosis of extra-intestinal microsporidiosis involving the lung, skin, and other organs, particularly in immunocompromised hosts Diagnosis of ocular microsporidiosis
MOC31 - Overview: MOC-31 Immunostain, Technical Component Only
Marker of epithelial cells
MYGLU - Overview: Myoglobin, Random, Urine
Confirming the presence of a myopathy
NEUN - Overview: Neu-N Immunostain, Technical Component Only
Identification of neuronal nuclei
SATB2 - Overview: SATB2 Immunostain, Technical Component Only
Identification of colorectal carcinoma and rectal neuroendocrine tumors
SSTR2 - Overview: Somatostatin Receptor 2 (SSTR2), Immunostain, Technical Component Only
Aids in the identification of neuroendocrine tumors
SMAD4 - Overview: SMAD4 Immunostain, Technical Component Only
Identification of loss of SMAD4 (mothers against decapentaplegic homolog 4 drosophila) expression within pancreatic ductal adenocarcinoma
CARNU - Overview: Carnitine, Random, Urine
Evaluation of patients with a clinical suspicion of a wide range of conditions including organic acidemias and fatty acid oxidation disorders Monitoring carnitine treatment
CO4D - Overview: Complement 4d Immunostain, Technical Component Only
Identification of antibody-mediated transplant rejection
FXCH - Overview: Coagulation Factor X Chromogenic Activity Assay, Plasma
Monitoring warfarin anticoagulant therapy, especially in patients whose plasma contains lupus anticoagulants that interfere with baseline prothrombin time/international normalized ratio and in patients receiving the drug Argatroban who are...
CYC1 - Overview: Cyclin D1 Immunostain, Technical Component Only
Classification of low-grade B-cell lymphomas
CD123 - Overview: CD123 Immunostain, Technical Component Only
Marker of plasmacytoid monocytes, mast cells, and megakaryocytes
CMET - Overview: cMET Immunostain, Technical Component Only
Identification of normal and neoplastic c-Met expressing cells
PDSUX - Overview: Drug Screen, Prescription/Over the Counter, Chain of Custody, Random, Urine
Qualitative detection and identification of prescription or over-the-counter drugs frequently found in drug overdose or used with a suicidal intent Providing, when possible, the identification of all drugs in the specimen This test is...
CERS - Overview: Ceruloplasmin, Serum
Investigation of patients with possible Wilson disease
MCEA - Overview: Carcinoembryonic Antigen, Monoclonal Immunostain, Technical Component Only
Marker of epithelial cells
CD99 - Overview: CD99 (MIC-2) Immunostain, Technical Component Only
Identification of Ewing sarcoma and primitive neuroectodermal tumors
CRPCR - Overview: Carbapenem Resistance Genes, Molecular Detection, PCR, Rectal Swab
Detecting and differentiating the blaKPC, blaNDM, blaVIM, blaOXA-48, and blaIMP gene sequences associated with carbapenem intermediate or resistant results Aiding in infection control in the detection of gastrointestinal colonization of...
CALD - Overview: Caldesmon Immunostain, Technical Component Only
As a marker of smooth muscle differentiation
CD10 - Overview: CD10 Immunostain, Technical Component Only
Phenotyping leukemias and lymphomas
HSCRP - Overview: C-Reactive Protein, High Sensitivity, Serum
Assessment of risk of developing myocardial infarction in patients presenting with acute coronary syndromes Assessment of risk of developing cardiovascular disease or ischemic events in individuals who do not manifest disease at present
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Detection of (1→3)-𝝱-D-glucan as a Marker of Invasive Fungal Disease - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....