COGBM - Overview: Chromosome Analysis, Hematologic Disorders, Children's Oncology Group Enrollment Testing, Bone Marrow

Evaluation of pediatric bone marrow specimens for chromosomal abnormalities associated with hematologic malignancies for diagnostic and prognostic purposes in patients being considered for enrollment in Children's Oncology Group clinical...

DRV3 - Overview: Dilute Russell's Viper Venom Time (DRVVT) Confirmation, Plasma

Confirming the presence or absence of lupus anticoagulants (LA) Identifying LA that do not prolong the activated partial thromboplastin time (APTT) Evaluating unexplained prolongation of the APTT or prothrombin time clotting tests...

NMS1 - Overview: Necrotizing Myopathy Evaluation, Serum

Evaluating patients with suspected necrotizing autoimmune myopathy

MBX - Overview: Muscle Pathology Consultation

Obtaining a rapid, expert opinion on muscle biopsy specimens for diagnosis of acquired or inherited muscle diseases Guiding treatment and genetic testing, as well as investigating relevance of genetic variants of unknown significance

HPWET - Overview: Hematopathology Consultation, MCL Embed

Obtaining a rapid, expert opinion for diagnosis of hematologic and non-hematologic diseases using unprocessed bone marrow biopsy specimens referred by the primary pathologist Obtaining special studies that are not available locally

PATHC - Overview: Pathology Consultation

A subspecialty second opinion for a specific pathology question referred by a primary pathologist Note: A consultative opinion is not a full rendering of a primary diagnostic report (eg, multiple parts, margin status, CAP...

NENZ - Overview: Red Blood Cell Enzyme Disorders Gene Panel, Next-Generation Sequencing, Varies

Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of an underlying red blood cell enzymopathy Identifying variants within genes associated with phenotypic severity, allowing for...

FCDU6 - Overview: Cocaine and Metabolites, Umbilical Cord Tissue

Cocaine and Metabolites, Umbilical Cord Tissue

FC9K - Overview: Factor IX Known Mutation Sequencing

Factor IX Known Mutation Sequencing

GNFIB - Overview: Congenital Fibrinogen Disorders, FGA, FGB, and FGG Genes, Next-Generation Sequencing, Varies

Evaluating congenital fibrinogen disorders (CFD) in patients with a personal or family history suggestive of a fibrinogen disorder Confirming a CFD diagnosis with the identification of known or suspected disease-causing alterations in the...

GNSPD - Overview: Platelet Storage Pool Deficiency Gene Panel, Next-Generation Sequencing, Varies

Evaluating hereditary platelet storage pool deficiencies in patients with a personal or family history suggestive of a hereditary platelet storage pool deficiency Diagnosing hereditary platelet storage pool deficiencies for patients in...

PIK3T - Overview: PIK3CA Mutation Analysis, Tumor

Identification of hormone receptor positive and human epidermal growth factor receptor 2 negative (HR+/HER2-) advanced breast cancer tumors that may be eligible for treatment with targeted kinase inhibitor therapy (eg, alpelisib).

PBGU - Overview: Porphobilinogen, Quantitative, Random, Urine

First-order test for evaluating a suspected acute porphyria: acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria

PARVS - Overview: Parvovirus B19 Antibodies, IgG and IgM, Serum

Serologic detection of recent or past parvovirus B19 infection

TDP - Overview: Thiamine (Vitamin B1), Whole Blood

Assessment of thiamine deficiency Measuring thiamine levels in patients with behavioral changes, eye signs, gait disturbances, delirium, and encephalopathy; or in patients with questionable nutritional status, especially those who appear...

TREE3 - Overview: Tree Panel #3, Serum

Establishing a diagnosis of an allergy to tress in panel #3 Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm...

WEED2 - Overview: Weed Panel # 2, Serum

Establishing a diagnosis of an allergy to English plantain, lamb's quarters, mugwort, scale, and Western ragweed allergen Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic...

VIBC - Overview: Vibrio Culture, Feces

Determining whether Vibrio species may be the cause of diarrhea This test is generally not useful for patients that have been hospitalized for more than 3 days because the yield from these patients' specimens is very low, as is the...

TCGR - Overview: T-Cell Receptor Gene Rearrangement, PCR, Blood

Determining whether a T-cell population is polyclonal or monoclonal using blood specimens

CIMRP - Overview: Coccidioides immitis/posadasii, Molecular Detection, PCR, Varies

Rapid detection of Coccidioides DNA, preferred method An aid in diagnosing coccidioidomycosis

PBLI - Overview: Plasma Cell Assessment, Blood

Detecting peripheral blood involvement by plasma cell proliferative disorders Establishing the diagnosis of and determining prognosis for plasma cell proliferative disorders

PU1 - Overview: PU.1 Immunostain, Technical Component Only

Classification of lymphomas

RPRT1 - Overview: Rapid Plasma Reagin (RPR) Screen with Reflex to Titer, Serum

Determining the current disease status Monitoring response to therapy for syphilis Aid to diagnose congenital syphilis This test cannot be used for testing spinal fluid specimens. This test is not intended for medical-legal use.

RPRT3 - Overview: Rapid Plasma Reagin (RPR) with Reflex to Treponema pallidum Particle Agglutination, Serum

Diagnosing syphilis

RSBV - Overview: Rare Subepithelial Autoimmune Blistering Disease Variants, Serum

Aiding in the diagnosis of rare subepithelial autoimmune blistering diseases, including anti-laminin 332 pemphigoid, anti-p200 pemphigoid, epidermolysis bullosa acquisita, and systemic bullous lupus erythematosus

P53 - Overview: p53 Immunostain, Technical Component Only

Aiding in the identification of neoplastic cells

FFMSS - Overview: Maternal Serum Screening, Integrated, Specimen #1, PAPP-A, NT

Helpful to identify pregnancies at increased risk of having a child with Down Syndrome (DS), open neural tube defects (ONTD) and trisomy 18 (T18). This test is not diagnostic.

UPGC - Overview: Uroporphyrinogen III Synthase (Co-Synthase), Erythrocytes

Diagnosis of congenital erythropoietic porphyria This test is not useful for diagnosis of acute intermittent porphyria (AIP).

WEED1 - Overview: Weed Panel # 1, Serum

Establishing a diagnosis of an allergy to English plantain, lamb's quarters, mugwort, Russian thistle, and short ragweed allergen Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for...

ROXUR - Overview: Oxalate, Random, Urine

Monitoring therapy for kidney stones using random urine specimens Identifying increased urinary oxalate as a risk factor for stone formation Diagnosis of primary or secondary hyperoxaluria

HD1 - Overview: House Dust Panel, Serum

Establishing a diagnosis of an allergy to cockroach, Dermatophagoides farinea, Dermatophagoides pteronyssinus, and house dust/H-S lab Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible...

UHBAG - Overview: Histoplasma and Blastomyces Antigen, Enzyme Immunoassay, Urine

Diagnosing Histoplasma capsulatum or Blastomyces dermatitidis infection without differentiation between the organisms Monitor antigen levels following initiation of antifungal treatment

HERGM - Overview: HER2, Gastric/Esophageal, Semi-Quantitative Immunohistochemistry, Manual

Determining overexpression of HER2 protein of gastric and esophageal adenocarcinoma in formalin-fixed, paraffin-embedded tissue sections (with reflex to FISH testing)

HK27M - Overview: Histone H3 K27M Mutant (H3 K27M) Immunostain, Technical Component Only

Identifying the presence of altered H3 K27M protein

GDS - Overview: Gadolinium, Serum

Aiding in documenting previous exposure to gadolinium-based contrast agents using serum specimens

GIAR - Overview: Giardia Antigen, Feces

Sensitive screening for the detection of Giardia antigens present in fecal specimens

FFRWB - Overview: Friedreich Ataxia, Frataxin, Quantitative, Blood

Diagnosing individuals with Friedreich ataxia in whole blood specimens Monitoring frataxin levels in patients with Friedreich ataxia This test is not useful for carrier detection.

FLT - Overview: FLT3 Mutation Analysis, Varies

Prognostic indication for some patients with acute myeloid leukemia This test should not be used to monitor residual disease following treatment.

SLEG - Overview: Legionella pneumophila (Legionnaires Disease), Antibody, Serum

Evaluating possible legionellosis (Legionnaires disease, Pontiac fever, extrapulmonary legionella infection caused by Legionella pneumophila)

MUCN6 - Overview: Mucin 6, Immunostain, Technical Component Only

Aiding in subtyping intraductal papillary mucinous neoplasms as part of an immunopanel

KKRP - Overview: Kingella kingae, Molecular Detection, PCR, Varies

Aiding in the diagnosis of Kingella kingae infection using tissue or synovial fluid specimens

MINT - Overview: Molecular Interpretation

Interpretation of the hereditary erythrocytosis profile

MSMN - Overview: Membranous Nephropathy Target Antigen Identification, Mass Spectrometry, Tissue

Identification of antigen in membranous nephropathy

MMLNS - Overview: Antimicrobial Susceptibility, Nocardia species and other Aerobic Actinomycetes, Varies

Determining the resistance of species of Nocardia and other aerobic actinomycetes to antimicrobial agents. This test is not useful for determining resistance of aerobic actinomycetes species of the following genera: Actinoallomurus,...

AERMC - Overview: Aeromonas Culture, Feces

Determining whether Aeromonas species may be the cause of diarrhea This test is generally not useful for patients hospitalized more than 3 days because the yield from specimens from these patients is very low, as is the likelihood of...

ALBR - Overview: Albumin, Random, Urine

Assessing the potential for early onset of nephropathy in diabetic patients using random urine specimens

AN1TC - Overview: Antineuronal Nuclear Antibody-Type 1 (ANNA-1) Titer, Spinal Fluid

Diagnosis of paraneoplastic autoimmune neuropathies, encephalomyeloradiculopathies, related neurologic disorders, and intestinal pseudo-obstruction/dysmotility associated with small-cell lung carcinoma Reporting an end titer result from...

APOLB - Overview: Apolipoprotein B, Serum

Assessment of cardiovascular risk Follow-up studies in individuals with basic lipid measures inconsistent with risk factors or clinical presentation Definitive studies of cardiac risk factors in individuals with significant family...

C2729 - Overview: Breast Carcinoma-Associated Antigen, Serum

Aiding in the management of breast cancer in patients with metastatic disease by monitoring the progression or regression of disease in response to treatment Serial testing in women with prior stage II or III breast cancer who are...

B210R - Overview: BCR/ABL1, p210, mRNA Detection, Reverse Transcription-PCR (RT-PCR), Quantitative, Reflex, Varies

Diagnostic workup of patients with a high probability of BCR-ABL1-positive hematopoietic neoplasms, particularly chronic myeloid leukemia and Ph+ acute lymphoblastic leukemia (B-lymphoblastic leukemia), to provide a pretreatment...