CFX - Overview: Protein C Activity, Plasma
As an initial test for evaluating patients suspected of having congenital protein C deficiency, including those with personal or family histories of thrombotic events Detecting and confirming congenital type I and type II protein C...
BRCMG - Overview: Brucella Antibody Screen, IgM and IgG, ELISA, Serum
Evaluating patients with suspected brucellosis
ML1HM - Overview: MLH1 Hypermethylation Analysis, Tumor
An adjunct to TMSI / Microsatellite Instability, Tumor and IHC / Mismatch Repair (MMR) Protein Immunohistochemistry Only, Tumor when colon or endometrial tumor demonstrates microsatellite instability (MSI-H) and loss of MLH1 protein...
STSH - Overview: Thyroid-Stimulating Hormone-Sensitive (s-TSH), Serum
Screening for thyroid dysfunction and detecting mild (subclinical), as well as overt, primary hypo- or hyperthyroidism in ambulatory patients Monitoring patients on thyroid replacement therapy Confirmation of thyrotropin (TSH, formerly...
GPSYP - Overview: Glucopsychosine, Plasma
Second-tier test when newborn screening results with reduced beta-glucosidase (GBA) activity are identified Diagnosis and monitoring of patients with Gaucher disease using plasma specimens Supporting a biochemical diagnosis of Gaucher...
OPATU - Overview: Opiates Confirmation, Random, Urine
Detection and quantification of codeine, hydrocodone, oxycodone, morphine, hydromorphone, oxymorphone, noroxycodone, noroxymorphone, norhydrocodone, dihydrocodeine, and naloxone in urine
TOXB - Overview: Toxoplasma gondii, Molecular Detection, PCR, Blood
Supporting the diagnosis of active toxoplasmosis, particularly in immunocompromised individuals
MANN - Overview: Alpha-Mannosidase, Leukocytes
Diagnosis of alpha-mannosidosis This test is not useful for establishing carrier status for alpha-mannosidosis.
VRERP - Overview: Vancomycin-Resistant Enterococcus, Molecular Detection, PCR, Varies
Identifying carriers of vancomycin-resistant enterococci
VIBC - Overview: Vibrio Culture, Feces
Determining whether Vibrio species may be the cause of diarrhea This test is generally not useful for patients that have been hospitalized for more than 3 days because the yield from these patients' specimens is very low, as is the...
CARFT - Overview: Carbamazepine, Free and Total, Serum
Monitoring carbamazepine (free and total) therapy in patients who are uremic
TIWB - Overview: Titanium, Blood
Detecting and monitoring titanium exposure and potential implant status in patients with orthopedic implants
HRTVS - Overview: Heartland Virus, RNA, Molecular Detection, PCR, Serum
Aiding in the diagnosis of central nervous system infection caused by Heartland virus using serum specimens
HEVM - Overview: Hepatitis E Virus IgM Antibody Screen with Reflex to Confirmation, Serum
Diagnosis of acute or recent (<6 months) hepatitis E infection
LALB - Overview: Lysosomal Acid Lipase, Blood
Evaluation of patients with a clinical presentation suggestive of lysosomal acid lipase deficiency using blood specimens This test is not useful to determine carrier status for cholesteryl ester storage disease or Wolman disease.
KKRP - Overview: Kingella kingae, Molecular Detection, PCR, Varies
Aiding in the diagnosis of Kingella kingae infection using tissue or synovial fluid specimens
KIDST - Overview: Kidney Stone Analysis
Managing patients with recurrent renal calculi (kidney stones)
MRDMR - Overview: Multiple Myeloma Minimal Residual Disease by Flow Cytometry, Bone Marrow
Detecting low level (minimal residual disease) myeloma cells after therapy to confirm remission has been achieved
FUCW - Overview: Alpha-Fucosidase, Leukocytes
Detection of fucosidosis This test is not useful for establishing carrier status for fucosidosis.
APIXA - Overview: Apixaban, Anti-Xa, Plasma
Measuring apixaban concentration in selected clinical situations (eg, renal insufficiency, assessment of compliance, periprocedural measurement of drug concentration, suspected overdose, advanced age, and extremes of body weight)
ALBR - Overview: Albumin, Random, Urine
Assessing the potential for early onset of nephropathy in diabetic patients using random urine specimens
C2729 - Overview: Breast Carcinoma-Associated Antigen, Serum
Aiding in the management of breast cancer in patients with metastatic disease by monitoring the progression or regression of disease in response to treatment Serial testing in women with prior stage II or III breast cancer who are...
Diagnostic workup of patients with a high probability of BCR-ABL1-positive hematopoietic neoplasms, particularly chronic myeloid leukemia and Ph+ acute lymphoblastic leukemia (B-lymphoblastic leukemia), to provide a pretreatment...
CCMVU - Overview: Congenital Cytomegalovirus (cCMV), Molecular Detection, PCR, Urine
Aiding in the rapid diagnosis of cytomegalovirus infections in neonates 21 days of age or younger using urine specimens
SALCT - Overview: Cortisol, Saliva
Screening for Cushing syndrome Diagnosis of Cushing syndrome in patients presenting with symptoms or signs suggestive of the disease
NBILI - Overview: Neonatal Bilirubin, Serum
Assessing liver function Evaluating a wide range of diseases affecting the production, uptake, storage, metabolism, or excretion of bilirubin Monitoring the efficacy of neonatal phototherapy
MAGRU - Overview: Magnesium/Creatinine Ratio, Random, Urine
Assessing the cause of abnormal serum magnesium concentrations Determining whether nutritional magnesium loads are adequate Calculating urinary calcium oxalate and calcium phosphate supersaturation and assessing kidney stone risk.
TPO - Overview: Thyroperoxidase Antibodies, Serum
Aiding in the diagnosis of thyroid autoimmune disorders Differentiating thyroid autoimmune disorders from nonautoimmune goiter or hypothyroidism As a diagnostic tool in deciding whether to treat a patient who has subclinical...
SCCTT - Overview: Chlamydia trachomatis, Self-Collect, Nucleic Acid Amplification, Throat
Detecting Chlamydia trachomatis using throat swabs collected by the patient in a healthcare setting This test is not intended for use in medico-legal applications. This test is not useful for the detection of other Chlamydia species.
SCCTV - Overview: Chlamydia trachomatis, Self-Collect, Amplified RNA, Vaginal
Detecting Chlamydia trachomatis using vaginal swabs collected by the patient in a healthcare setting This test is not intended for use in medico-legal applications. This test is not useful for the detection of other Chlamydia species.
CMVM - Overview: Cytomegalovirus (CMV) Antibodies, IgM, Serum
Aiding in the diagnosis of acute infection with cytomegalovirus This test should not be used for screening blood or plasma donors.
FCDSU - Overview: Comprehensive Drug Screen, Umbilical Cord Tissue
Comprehensive Drug Screen, Umbilical Cord Tissue
EAEBV - Overview: Epstein-Barr Virus Early Antigen, IgG, Serum
Diagnosis of Epstein Barr virus (EBV) infectious mononucleosis in cases when heterophile antibody test results are negative and EBV-specific serologic testing is inconclusive Aiding in the diagnosis of type 2 or type 3 nasopharyngeal...
PRCAL - Overview: Procalcitonin, Serum
Monitoring antibiotic therapy and all-cause mortality for patients diagnosed with severe sepsis or septic shock in the Intensive Care Unit (ICU) or when obtained in the emergency department or other medical wards prior to ICU admission
C1QFX - Overview: C1q Complement, Functional, Serum
Diagnosis of C1 deficiency Investigation of a patient with an absent total complement level
Detecting in utero drug exposure to marijuana (tetrahydrocannabinol) up to 5 months before birth Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the...
SCCTR - Overview: Chlamydia trachomatis, Self-Collect, Nucleic Acid Amplification, Rectal
Detecting Chlamydia trachomatis using rectal swabs collected by the patient in a healthcare setting This test is not intended for use in medico-legal applications. This test is not useful for the detection of other Chlamydia species.
POSA - Overview: Posaconazole, Serum
Monitoring posaconazole therapy
VORI - Overview: Voriconazole, Serum
Monitoring trough levels of voriconazole is suggested for: -Individuals with reduced liver function -Individuals with cytochrome P450 (CYP) 2C19 alterations associated with poor metabolic function -Patients taking other medications that...
B2MU - Overview: Beta-2 Microglobulin, Random, Urine
Evaluation of renal tubular damage Monitoring exposure to cadmium and mercury
CD21 - Overview: CD21 Immunostain, Technical Component Only
Identification of follicular dendritic cells and a subset of mantle zone lymphocytes
D240 - Overview: Podoplanin (D2-D40) Immunostain, Technical Component Only
Aids in the identification of reactive follicular dendritic cells
UPII - Overview: Uroplakin II Immunostain, Technical Component Only
Characterization of urothelial carcinoma
HPL - Overview: Human Placental Lactogen Immunostain, Technical Component Only
Aids in the identification of placenta-related tumors
LY27B - Overview: HLA-B27, Blood
Assisting in the diagnostic process of ankylosing spondylitis, juvenile rheumatoid arthritis, and reactive arthritis
HIBSG - Overview: Haemophilus influenzae Type B Antibody, IgG, Serum
Assessing a patient's immunological (IgG) response to Haemophilus influenzae type B (HIB) vaccine Assessing immunity against HIB Aiding in the evaluation of immunodeficiency when the patient is tested pre- and post-vaccination
FUSI - Overview: FUS Immunostain, Technical Component Only
Identification of frontotemporal lobar dementia
GD65C - Overview: Glutamic Acid Decarboxylase (GAD65) Antibody Assay, Spinal Fluid
Possible use in evaluating patients with autoimmune encephalitis, stiff-person syndrome, autoimmune ataxia, autoimmune epilepsy, and other acquired central nervous system disorders affecting gabaminergic neurotransmission
MSFGN - Overview: Fibrillary Glomerulonephritis Confirmation, Mass Spectrometry, Paraffin Tissue
Diagnosing fibrillary glomerulonephritis
GABA - Overview: Gabapentin, Serum
Monitoring serum gabapentin concentrations Assessing compliance Adjusting dosage in patients
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Detection of (1→3)-𝝱-D-glucan as a Marker of Invasive Fungal Disease - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....