AMPHM - Overview: Amphetamine-Type Stimulants Confirmation, Meconium

Detecting in utero exposure to amphetamine-type stimulants up to 5 months before birth

WNVCI - Overview: West Nile CSF Interpretation

Interpretation of testing for a laboratory diagnosis of infection with West Nile virus using spinal fluid specimens Aids in diagnosis of central nervous system infection with West Nile virus

WNVSI - Overview: West Nile Serum Interpretation

Interpretation of testing for a laboratory diagnosis of infection with West Nile virus

INHIB - Overview: Inhibin Immunostain, Technical Component Only

Identifying sex cord-stromal tumors

AMIO - Overview: Amiodarone, Serum

Monitoring amiodarone therapy, especially when amiodarone is coadministered with other drugs that may interact Evaluating possible amiodarone toxicity Assessing patient compliance

ZNU - Overview: Zinc, 24 Hour, Urine

Identifying the cause of abnormal serum zinc concentrations using 24-hour urine specimens

ZONI - Overview: Zonisamide, Serum

Monitoring zonisamide therapy; recommended for all patients to ensure appropriate dosing Assessing medication compliance

IFXED - Overview: Immunofixation Heavy Chain Type Delta and Epsilon, Serum

Identification and isotyping of IgD or IgE monoclonal gammopathy Documentation of complete response to therapy with established monoclonal gammopathy consisting of an IgD or IgE heavy chain

CLOBZ - Overview: Clobazam and Metabolite, Serum

Monitoring clobazam therapy

FENTS - Overview: Fentanyl, Serum

Monitoring fentanyl therapy

AACYL - Overview: Aminoacylase-1 Deficiency, Urine

Follow-up quantitation of abnormal organic acid elevations of N-acetylated amino acids, in particular N-acetylalanine, N-acetylglycine, N-acetylmethionine, and N-acetylglutamic acid Diagnosis of individuals with aminoacylase-1...

OSM24 - Overview: Osmolality, 24 Hour, Urine

Assessing the concentrating and diluting ability of the kidney using a 24-hour urine collection

LGBWB - Overview: Globotriaosylsphingosine, Blood

Screening of patients with Fabry disease when a serum specimen is not available This test should not be used for newborn screening followup.

EPS2 - Overview: Epilepsy, Autoimmune/Paraneoplastic Evaluation, Serum

Investigating new onset cryptogenic epilepsy with incomplete seizure control and duration of less than 2 years, using serum specimens Investigating new onset cryptogenic epilepsy plus 1 or more of the following accompaniments: -Psychiatric...

AHLP - Overview: AudioloGene Hearing Loss Panel, Varies

Establishing a diagnosis of a syndromic or nonsyndromic hereditary hearing loss disorder Identifying variants within genes known to be associated with hereditary hearing loss, allowing for predictive testing of at-risk family members

NMITO - Overview: Nuclear Mitochondrial Gene Panel, Next-Generation Sequencing, Varies

Diagnosing the subset of mitochondrial disease that results from variants in the nuclear-encoded genes A second-tier test for patients in whom previous targeted gene variant analyses for specific mitochondrial disease-related genes were...

GNSPD - Overview: Platelet Storage Pool Deficiency Gene Panel, Next-Generation Sequencing, Varies

Evaluating hereditary platelet storage pool deficiencies in patients with a personal or family history suggestive of a hereditary platelet storage pool deficiency Diagnosing hereditary platelet storage pool deficiencies for patients in...

GNPFD - Overview: Platelet Function Defect Gene Panel, Next-Generation Sequencing, Varies

Diagnosing hereditary platelet function defect disorders for patients who have a distinct platelet function defect pattern, such as Bernard-Soulier syndrome, revealed by laboratory phenotypic testing Confirming a hereditary platelet...

WESR - Overview: Whole Exome Sequencing Reanalysis, Varies

Identifying a diagnosis or additional variants associated with the phenotype in patients who previously have had a negative or inconclusive whole exome sequencing test Reanalyzing whole exome sequencing data when a patient (proband)...

PLSD - Overview: Lysosomal and Peroxisomal Disorders Screen, Blood Spot

Evaluation of patients with a clinical presentation suggestive of a lysosomal disorder, specifically Gaucher, infantile neurovisceral or chronic visceral acid sphingomyelinase deficiency, Pompe, Krabbe, or Fabry disease, or...

SQTSG - Overview: Short QT Syndrome Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of short QT syndrome Establishing a diagnosis of short QT syndrome

PAVAL - Overview: Paraneoplastic, Autoantibody Evaluation, Serum

Serological evaluation of patients who present with a subacute neurological disorder of undetermined etiology, especially those with known risk factors for cancer Directing a focused search for cancer Investigating neurological symptoms...

EPPAN - Overview: Comprehensive Epilepsy With or Without Encephalopathy Gene Panel, Varies

Establishing a diagnosis of an epilepsy or seizure disorder associated with known causal genes Identifying disease-causing variants within genes known to be associated with inherited epilepsy or seizure disorders, allowing for predictive...

HYPBG - Overview: Hypobetalipoproteinemia Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of familial hypobetalipoproteinemia

ALDU - Overview: Aldosterone, 24 Hour, Urine

Investigating primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter...

B190R - Overview: BCR/ABL1, p190, mRNA Detection, Reverse Transcription-PCR (RT-PCR), Quantitative, Reflex, Varies

Diagnostic workup of patients with a high probability of BCR-ABL1-positive hematopoietic neoplasms, particularly acute lymphoblastic leukemia (B-lymphoblastic leukemia), to provide a pretreatment quantitative level of BCR-ABL1 mRNA...

BVRNA - Overview: Bacterial Vaginosis, Nucleic Acid Amplification, Vaginal

Aid for diagnosis of bacterial vaginosis This test is not intended for use in medico-legal applications.

BILAO - Overview: Biliary Tract Malignancy, FISH, Varies

Assessing bile duct brushing or hepatobiliary brushing specimens for biliary tract malignancy

BUPMX - Overview: Buprenorphine and Norbuprenorphine, Chain of Custody, Random, Urine

Monitoring of compliance of buprenorphine therapy Detection and confirmation of the illicit use of buprenorphine Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the...

BRG1 - Overview: BRG1 (SMARCA4) Immunostain, Technical Component Only

Diagnosing ovarian small cell carcinoma of hypercalcemic type (SCCOHT)

BIVAL - Overview: Bivalirudin, Ecarin, Plasma

Monitoring of bivalirudin therapy for patients with prolonged baseline activated partial thromboplastin time

BART - Overview: Bartonella Antibody Panel, IgG and IgM, Serum

Diagnosis of Bartonella infection, especially in the context of a cat scratch

APIXA - Overview: Apixaban, Anti-Xa, Plasma

Measuring apixaban concentration in selected clinical situations (eg, renal insufficiency, assessment of compliance, periprocedural measurement of drug concentration, suspected overdose, advanced age, and extremes of body weight)

AMBF - Overview: Amylase, Body Fluid

Evaluation of patients with a pathological accumulation of fluid to determine whether pancreatic inflammation, pancreatic fistula, or esophageal rupture may be contributing Aiding in the diagnosis of pancreatitis

AFPPT - Overview: Alpha-Fetoprotein (AFP), Peritoneal Fluid

An adjunct to cytology to differentiate between malignancy-related ascites and benign causes of ascites formation

FUCW - Overview: Alpha-Fucosidase, Leukocytes

Detection of fucosidosis This test is not useful for establishing carrier status for fucosidosis.

WASQR - Overview: Alpha-Globin Gene Sequencing, Blood

Testing for nondeletional alpha thalassemia in a symptomatic individual Follow-up testing to an abnormal hemoglobin electrophoresis that identified an alpha-globin chain variant Evaluating for nondeletional alpha thalassemias in an...

ACTH - Overview: Adrenocorticotropic Hormone, Plasma

Determining the cause of hypercortisolism and hypocortisolism

AMISO - Overview: Amylase, Isoenzymes, Serum

Ruling out salivary amylase as the cause of elevated serum amylase

APOLB - Overview: Apolipoprotein B, Serum

Assessment of cardiovascular risk Follow-up studies in individuals with basic lipid measures inconsistent with risk factors or clinical presentation Definitive studies of cardiac risk factors in individuals with significant family...

C4U - Overview: C4 Acylcarnitine, Quantitative, Random, Urine

Evaluation of patients with abnormal newborn screens showing elevations of iso-/butyrylcarnitine to aid in the differential diagnosis of short-chain acyl-CoA dehydrogenase and isobutyryl-CoA dehydrogenase deficiencies

C9FX - Overview: C9 Complement, Functional, Serum

Diagnosis of C9 deficiency Investigation of a patient with a low total (hemolytic) complement level

HMHA - Overview: Heavy Metals, Hair

Detection of nonacute arsenic, mercury, and lead exposure using hair specimens

AHDV - Overview: Hepatitis D Virus Total Antibodies, Serum

Detection of hepatitis D virus (HDV)-specific total antibodies (combined IgG and IgM) in human serum Diagnosis of concurrent HDV infection in patients with fulminant acute hepatitis B virus (HBV) infection (acute coinfection), chronic HBV...

UIOD - Overview: Iodine, 24 Hour, Urine

Assessing iodine toxicity or recent exposure in a 24-hour urine collection Monitoring iodine excretion rate as index of replacement therapy

IL5P - Overview: Interleukin 5, Plasma

Evaluation of patients with disorders known to be associated with hypereosinophilia

CAURS - Overview: Candida auris Surveillance, Molecular Detection, PCR, Varies

Detecting Candida auris from surveillance swabs This test should not be used to determine cure or to monitor response to therapy.

CD34I - Overview: CD34 Immunostain, Technical Component Only

A marker of immaturity in the setting of acute myeloid leukemia or B-cell lymphoblastic leukemia Diagnosis of gastrointestinal stromal tumors, solitary fibrous tumors, and angiosarcomas

COU - Overview: Cobalt, 24 Hour, Urine

Detecting cobalt exposure Monitoring metallic prosthetic implant wear This test is not useful to assess vitamin B12 activity.

CARNU - Overview: Carnitine, Random, Urine

Evaluation of patients with a clinical suspicion of a wide range of conditions including organic acidemias and fatty acid oxidation disorders Monitoring carnitine treatment