CLAUD - Overview: Claudin-1 Immunostain, Technical Component Only

Identification of a number of different soft tissue and epithelial neoplasms

DOG1 - Overview: DOG-1 Immunostain, Technical Component Only

Identification of gastrointestinal stromal tumors

HBZ - Overview: Human T-cell Lymphotropic Virus Type 1 (HTLV-1) bZIP Factor (HBZ), In Situ Hybridization, Technical Component Only

Diagnosing adult T-cell leukemia/lymphoma

LKM - Overview: Liver/Kidney Microsome Type 1 Antibodies, Serum

Evaluation of patients with liver disease of unknown etiology Evaluation of patients with suspected autoimmune hepatitis

MUM1 - Overview: MUM-1/IRF4 Immunostain, Technical Component Only

Aids in the identification of hematolymphoid neoplasms and melanomas

CD279 - Overview: CD279 (PD-1) Immunostain, Technical Component Only

Identification of follicular T helper cells Phenotyping of angioimmunoblastic T-cell lymphoma

GALTP - Overview: Galactose-1-Phosphate Uridyltransferase Biochemical Phenotyping, Erythrocytes

Determining the biochemical phenotype for galactosemia when enzymatic and molecular results are incongruent

WT1I - Overview: Wilms Tumor (WT-1) Immunostain, Technical Component Only

Aiding in the identification of Wilms tumor

KI67 - Overview: Ki-67 (MIB-1) Immunostain, Technical Component Only

A marker of proliferation in neoplasms

KIPM - Overview: Ki-67(MIB-1), Pulmonary, Quantitative Immunohistochemistry, Manual

Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with carcinoid or atypical carcinoid of the lung including metastases, using a manual method

KI67P - Overview: Ki-67(MIB-1), Pulmonary, Quantitative Immunohistochemistry, Automated

Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with carcinoid or atypical carcinoid of the lung including metastases

KI67B - Overview: Ki-67(MIB-1), Breast, Quantitative Immunohistochemistry, Automated

Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with breast carcinoma

HBME - Overview: Mesothelial Cell (HBME-1) Immunostain, Technical Component Only

Classification of thyroid carcinomas

THSD7 - Overview: Thrombospondin Type-1 Domain-Containing 7A Antibodies, Serum

Distinguishing primary from secondary membranous nephropathy cases with antibodies against THSD7A

MELAN - Overview: Melan A (MART-1) Immunostain, Technical Component Only

Aids in the identification of melanoma

CYTH1 - Overview: T-Helper Cell Type 1 Cytokine Panel, Plasma

Assessment of plasma cytokine levels to understand the etiology of autoimmune and proinflammatory conditions when used in conjunction with clinical information and other laboratory testing

IGFMS - Overview: Insulin-Like Growth Factor-1, Mass Spectrometry, Serum

Evaluation of growth disorders Evaluation of growth hormone deficiency or excess in children and adults Monitoring of recombinant human growth hormone treatment Follow-up of individuals with acromegaly and gigantism

TRPS1 - Overview: Trichorhinophalangeal syndrome type 1 (TRPS1) Immunostain, Technical Component Only

Identification of breast carcinoma including triple negative breast cancer

TTF8G - Overview: Thyroid Transcription Factor (8G7G3/1) Immunostain, Technical Component Only

Identification of thyroid or lung cells as the primary tumor site in carcinomas of unknown origin

MYOD1 - Overview: Myogenic Differentiation Antigen 1 (MYOD1) Immunostain, Technical Component Only

Marker of skeletal muscle differentiation

FFMSS - Overview: Maternal Serum Screening, Integrated, Specimen #1, PAPP-A, NT

Helpful to identify pregnancies at increased risk of having a child with Down Syndrome (DS), open neural tube defects (ONTD) and trisomy 18 (T18). This test is not diagnostic.

FGFRC - Overview: Fibroblast Growth Factor Receptor 1, Immunostain, Technical Component Only

Classification of a subset of lung squamous cell carcinoma

KIBM - Overview: Ki-67(MIB-1), Breast, Semi-Quantitative Immunohistochemistry, Manual

Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with breast carcinoma

INSM1 - Overview: Insulinoma-Associated Protein 1 (INSM1), Immunostain, Technical Component Only

Identification of neuroendocrine tumors

INI1 - Overview: Integrase Interactor 1 (INI1/BAF47) Immunostain, Technical Component Only

Part of a panel of immunostains where loss of staining can be used as a marker of various neoplasms

MUM1B - Overview: MUM-1/IRF4 Immunostain, Bone Marrow, Technical Component Only

Aiding in the identification of hematolymphoid neoplasms and melanomas

DSGAB - Overview: Desmoglein 1 (DSG1) and Desmoglein 3 (DSG3), IgG Antibodies, Serum

Preferred screening test for patients suspected to have an autoimmune blistering disorder of the skin or mucous membranes (pemphigus) Aiding in the diagnosis of pemphigus

GAB1 - Overview: GRB2-Associated Binding Protein 1 (GAB1) Immunostain, Technical Component Only

Identification and differentiation of medulloblastomas

LEF1 - Overview: Lymphoid Enhancer-Binding Factor 1(LEF1) Immunostain, Technical Component Only

Differentiating cancers of B-cell origin

CAMTA - Overview: Calmodulin-Binding Transcription Activator 1 (CAMTA1), Immunostain, Technical Component Only

Aids in the diagnosis of epithelioid hemangioendotheliomas

TYRBS - Overview: Tyrosinemia Follow Up Panel, Blood Spot

Monitoring of individuals with tyrosinemia type 1 (HT-1) Diagnosis of HT-1 when used in conjunction with testing for urine organic acids, liver function, alpha-fetoprotein, and molecular genetic analysis of the fumarylacetoacetate...

F8INP - Overview: Hemophilia A F8 Gene, Intron 1 and 22 Inversion Mutation Analysis, Prenatal

Prenatal testing for hemophilia A when a variant has not been identified in the family

GCET - Overview: Germinal Center B-cell Expressed Transcript 1 Immunostain, Technical Component Only

Classification of lymphomas

KINET - Overview: Ki-67(MIB-1), Gastrointestinal/Pancreatic Neuroendocrine Tumors, Quantitative Immunohistochemistry, Automated

Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with neuroendocrine tumors of the pancreas or gastrointestinal tract including metastases

KINM - Overview: Ki-67(MIB-1), Gastrointestinal/Pancreatic Neuroendocrine Tumors, Quantitative Immunohistochemistry, Manual

Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with neuroendocrine tumors of the pancreas or gastrointestinal tract including metastases

LMP1I - Overview: Epstein Barr Virus Latency Membrane Protein 1 Immunostain, Technical Component Only

Identification of Epstein Barr virus infection in normal, inflammatory, and neoplastic tissues

KRASW - Overview: KRAS Somatic Mutation Analysis, Peritoneal Fluid

Staging of the pancreatic ductal adenocarcinoma(1)

SUAC - Overview: Succinylacetone, Blood Spot

Second-tier newborn screen for tyrosinemia type 1 (HT-1) when primary screen showed nonspecific elevations of tyrosine Diagnosing HT-1 when used in conjunction with testing for urine organic acids, liver function, alpha-fetoprotein, and...

SCARA - Overview: Spinocerebellar Ataxia Type 1, 2, 3, 6, or 7, Repeat Expansion Analysis, Varies

Diagnostic or predictive testing when clinical symptoms or a family history are specific to only one type of spinocerebellar ataxia

F8INV - Overview: Hemophilia A F8 Gene, Intron 1 and 22 Inversion Mutation Analysis, Whole Blood

First-tier molecular testing for male patients affected with severe hemophilia A when a variant has not been identified in the family Determining hemophilia A carrier status for at-risk female patients, ie, individuals with a family...

PRKSG - Overview: PRKAR1A Full Gene Sequencing with Deletion/Duplication, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of Carney Complex (CNC) or acrodysostosis-1 with hormone resistance Establishing a diagnosis of CNC or acrodysostosis-1 with hormone resistance

TTFK5 - Overview: Thyroid Transcription Factor 1 (TTF1) (SPT24) and Keratin 5 (KRT5) Immunostain, Technical Component Only

Thyroid transcription factor 1aids in the classification of carcinomas of unknown origin Keratin 5 aids in the identification of squamous cell carcinoma

DDITT - Overview: D-Dimer, Plasma

Excluding the diagnosis of acute pulmonary embolism or deep vein thrombosis, particularly when results of a sensitive D-dimer assay are combined with clinical information, including pretest disease probability(1-4) Diagnosis of...

BRAZX - Overview: Brazil Nut Component, IgE, Serum

Evaluation of patients with suspected Brazil nut allergy to component Ber e 1

IA2 - Overview: Islet Antigen 2 (IA-2) Antibody, Serum

Clinical distinction of type 1 from type 2 diabetes mellitus Identification of individuals at risk of type 1 diabetes (including high-risk relatives of patients with diabetes) Prediction of future need for insulin treatment in...

CERAM - Overview: MI-Heart Ceramides, Plasma

Evaluating the risk of major adverse cardiovascular events within the next 1 to 5 years

RPR1 - Overview: Respiratory Profile, Region 1, North Atlantic (CT, MA, ME, NJ, NH, NY, PA, RI, VT), Serum

Assessing sensitization to various inhalant allergens commonly found in the North Atlantic region including Connecticut, Maryland, Maine, New Hampshire, New Jersey, New York, Pennsylvania, Rhode Island, and Vermont Defining the allergen...

FFTRP - Overview: Trofile Co-Receptor Tropism Assay

Detect HIV-1 coreceptor tropism; determine eligibility for CCR5 antagonist therapy such as maraviroc (Selzentry)

LAGU - Overview: Legionella Antigen, Random, Urine

An adjunct to culture for the detection of past or current Legionnaires disease (Legionella pneumophila serogroup 1)

GCLIP - Overview: Phospholipid (Cardiolipin) Antibodies, IgG, Serum

The following clinical situations, when used in conjunction with other criterial antiphospholipid antibody tests: -Unexplained arterial or venous thrombosis -A history of pregnancy morbidity defined as 1 or more unexplained deaths of a...