TAMIK - Overview: Amikacin, Trough, Serum
Monitoring adequate clearance of amikacin near the end of a dosing cycle
PBR - Overview: Phenobarbital, Serum
Monitoring for appropriate therapeutic concentration of phenobarbital Assessing compliance or toxicity
DOGPF - Overview: Dog Dander, IgE, with Reflex to Dog Dander Components, IgE, Serum
Evaluating patients with suspected dog dander allergy
SAT - Overview: Percent Saturation
Calculation of percent saturation
HGCU - Overview: Mercury/Creatinine Ratio, Random, Urine
Detecting mercury toxicity using random urine specimens
TPIC - Overview: Triosephosphate Isomerase Enzyme Activity, Blood
Evaluating individuals with chronic nonspherocytic hemolytic anemia Evaluating individuals with early onset neurologic impairment Genetic counseling for families with triosephosphate isomerase deficiency
BWRS - Overview: Beckwith-Wiedemann Syndrome/Russell-Silver Syndrome, Molecular Analysis, Varies
Confirming a clinical diagnosis of Beckwith-Wiedemann syndrome (BWS) or Russell-Silver syndrome (RSS) Prenatal diagnosis if there is a high suspicion of BWS/RSS based on ultrasound findings or in families at risk for BWS/RSS This assay...
APOA1 - Overview: Apolipoprotein A1, Serum
Evaluating risk for atherosclerotic cardiovascular disease Aiding in the detection of Tangier disease
MTHX - Overview: Methotrexate, Serum
Determining whether methotrexate is being cleared appropriately and verifying that a nontoxic concentration has been attained following therapy
QUAD1 - Overview: Quad Screen (Second Trimester) Maternal, Serum
Prenatal screening for open neural tube defect (alpha-fetoprotein only), trisomy 21 (alpha-fetoprotein, human chorionic gonadotropin, estriol, and inhibin A) and trisomy 18 (alpha-fetoprotein, human chorionic gonadotropin, and estriol)
NITF - Overview: Nitrogen, Total, Feces
Determining nitrogen balance, when used in conjunction with 24-hour urine nitrogen measurement Assessing nutritional status (protein malnutrition) Evaluating protein catabolism
Aiding in the evaluation of iron deficiency and iron overload diseases in combination with total iron binding capacity and percent saturation Assessment of acute iron poisoning
A2PI - Overview: Alpha-2 Plasmin Inhibitor, Plasma
Diagnosing congenital alpha-2 plasmin inhibitor deficiencies (rare) Providing a complete assessment of disseminated intravascular coagulation, intravascular coagulation and fibrinolysis, or hyperfibrinolysis (primary fibrinolysis), when...
CARU - Overview: Cyclic Adenosine Monophosphate (cAMP), Urinary Excretion, Serum and Urine
Differential diagnosis of hypercalcemia As an adjunct to serum parathyroid hormone measurements, especially in the diagnosis of parathyroid hormone resistance states, such as pseudohypoparathyroidism
CA - Overview: Calcium, Total, Serum
Diagnosis and monitoring of a wide range of disorders including diseases of bone, kidney, parathyroid gland, or gastrointestinal tract
F_9 - Overview: Coagulation Factor IX Activity Assay, Plasma
Diagnosing deficiencies, particularly hemophilia B (Christmas disease) Assessing the impact of liver disease on hemostasis Investigation of a prolonged activated partial thromboplastin time
NAU - Overview: Sodium, 24 Hour, Urine
Assessing acid-base balance, water balance, water intoxication, and dehydration
SULFU - Overview: Sulfate, 24 Hour, Urine
Assessing the nutrition intake of animal protein The calculation of urinary supersaturation of various crystals or stones
KETGP - Overview: Ketone Disorders Gene Panel, Varies
Follow up for abnormal biochemical results suggestive of a ketone disorder Establishing a molecular diagnosis for patients with ketone disorders Identifying variants within genes known to be associated with ketone disorders, allowing for...
URCU - Overview: Uric Acid, 24 Hour, Urine
Assessment and management of patients with kidney stones, particularly uric acid stones
MA2EC - Overview: Ma2 Antibody, ELISA, Spinal Fluid
Evaluating patients with suspected paraneoplastic encephalitides using spinal fluid specimens
GQ1ES - Overview: Ganglioside GQ1b Antibody, IgG, ELISA, Serum
Evaluating patients with an underlying demyelinating neuropathy Supporting the diagnosis of a ganglioside GQ1b IgG-related disorder
IGGS4 - Overview: IgG4, Immunoglobulin Subclasses, Serum
Supporting the diagnosis of IgG4-related disease
CLOM - Overview: Clomipramine, Serum
Determining whether a poor therapeutic response is attributable to noncompliance Monitoring serum concentration of clomipramine and norclomipramine to assist in optimizing the administered dose
PACP - Overview: Prostatic Acid Phosphatase, Serum
Aiding in predicting recurrence after radical prostatectomy for clinically localized prostate cancer Following response to androgen ablation therapy, when used in conjunction with prostate-specific antigen
MA2ES - Overview: Ma2 Antibody by ELISA, Serum
Evaluating patients with suspected paraneoplastic encephalitides using serum specimens
UPH24 - Overview: pH, 24 Hour, Urine
Assessment of patients with metabolic acidosis, crystalluria, as well as monitoring the effectiveness of alkalinization or acidification of urine for certain medical conditions (eg, treatment of uric acid nephrolithiasis) using a 24-hour...
MPHNU - Overview: Methylphenidate and Metabolite, Random, Urine
Monitoring urine methylphenidate and ritalinic acid concentrations to assess compliance in patients
CH8B - Overview: Chromogenic Factor VIII Inhibitor Bethesda Titer, Plasma
Detecting the presence and titer of a specific factor inhibitor directed against coagulation factor VIII This test is not useful for detecting the presence of inhibitors directed against other clotting factors and will not detect the...
CALC5 - Overview: Calcium, Random, Urine
Measurement of calcium for the evaluation of calcium oxalate and calcium phosphate kidney stone risk, and calculation of urinary supersaturations Evaluation of bone diseases, including osteoporosis and osteomalacia
VALPF - Overview: Valproic Acid, Free, Serum
Monitoring free valproic acid in therapy Assessing compliance Evaluating potential toxicity
NARC - Overview: Narcolepsy-Associated Antigen, HLA-DQB1 Typing, Blood
Ruling out a diagnosis of narcolepsy
SPIRO - Overview: Spirochete Immunostain, Technical Component Only
This test will identify spirochete organisms in cases of intestinal spirochetosis, as well as cases of syphilis caused by infection with the spirochete Treponema pallidum.
FER - Overview: Semen Analysis, Semen
Determining male fertility status
HDCH - Overview: Cholesterol, High-Density Lipoprotein (HDL), Serum
Measurement of serum high-density lipoprotein concentrations for managing atherosclerotic cardiovascular disease risk
CPAPS - Overview: Conventional Smear-Screen, Varies
Screening for cervical carcinoma and a number of infections of the female genital tract including human papillomavirus, herpes, Candida, and Trichomonas
K818 - Overview: Keratin 8 and 18 (KRT8/18), Technical Component only
Aiding in the diagnosis of carcinomas
F_10 - Overview: Coagulation Factor X Activity Assay, Plasma
Diagnosing deficiency of coagulation factor X, congenital or acquired Evaluating hemostatic function in liver disease Investigation of prolonged prothrombin time or activated partial thromboplastin time
PTU - Overview: Protein, Total, 24 Hour, Urine
Evaluation of kidney disease using a 24-hour urine collection Screening for monoclonal gammopathy
TLU - Overview: Thallium, 24 Hour, Urine
Detecting toxic thallium exposure in 24-hour urine collections
CPAPD - Overview: Conventional Smear-Diagnostic, Varies
Screening for cervical carcinoma and a number of infections of the female genital tract including human papillomavirus, herpes, Candida, and Trichomonas
HGUOE - Overview: Mercury Occupational Exposure, Random, Urine
Detecting mercury toxicity due to occupational exposure
PTSC - Overview: Prothrombin Time (PT), Plasma
Screening to identify a deficiency of one or more of the clotting factors of the extrinsic coagulation system (I, II, V, VII, X) due to hereditary deficiency or acquired conditions such as liver disease, vitamin K deficiency, or a specific...
KUR - Overview: Potassium, 24 Hour, Urine
Determining the cause for hyper- or hypokalemia
AC1Q - Overview: Anti-C1q Antibodies, IgG, Serum
Evaluating patients with suspected anti-C1q vasculitis Predicting renal involvement in patients with systemic lupus erythematosus Detection of anti-C1q antibodies in serum
A2M - Overview: Alpha-2-Macroglobulin, Serum
Evaluating patients with nephrotic syndrome and pancreatitis
GAAWR - Overview: Acid Alpha-Glucosidase Reflex, Leukocytes
Diagnosis of Pompe disease as a confirmatory reflex of the 6-enzyme panel
ACE - Overview: Angiotensin Converting Enzyme, Serum
Evaluation of patients with suspected sarcoidosis
BIOTN - Overview: Biotin, Serum
Measurement of biotin in serum Assessment of biotin concentrations in individuals taking biotin supplements Investigation of unexpected results from immunoassays that utilize biotin-streptavidin detection methods This test is not useful...
CLU - Overview: Chloride, 24 Hour, Urine
Indication of fluid balance and acid-base homeostasis using a 24-hour urine collection
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Detection of (1→3)-𝝱-D-glucan as a Marker of Invasive Fungal Disease - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....