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Detection of high-risk (HR) genotypes associated with the development of cervical cancer An aid in triaging women with abnormal Pap smear test results Individual genotyping of human papillomavirus (HPV)-16 and/or HPV-18, if present...

ALPGP - Overview: Alport Syndrome Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of Alport syndrome Establishing a diagnosis of Alport syndrome

SCOF3 - Overview: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) and Influenza Virus Type A and Type B RNA, Molecular Detection, PCR, Varies

Simultaneous detection and differentiation of SARS-CoV-2 (cause of COVID-19), influenza A virus, and influenza B virus in upper or lower respiratory tract specimens from individuals with flu-like illnesses

MCLBP - Overview: MayoComplete Liquid Biopsy Panel, Next-Generation Sequencing, Cell-Free DNA

As an alternative to invasive tissue biopsies to assist in tumor profiling for diagnosis, predicting prognosis, and identifying targeted therapies for the treatment and management of patients with solid tumors As an alternative to invasive...

DGGL - Overview: Gliadin (Deamidated) Antibody, IgG, Serum

Assessment of deaminated gliadin IgG antibodies for evaluating patients suspected of having celiac disease, including patients with compatible clinical symptoms, patients with atypical symptoms, and individuals at increased risk (family...

COGBL - Overview: Chromosome Analysis, Hematologic Disorders, Children's Oncology Group Enrollment Testing, Blood

Evaluation of pediatric blood specimens for chromosomal abnormalities associated with hematologic malignancies for diagnostic and prognostic purposes in patients being considered for enrollment in Children's Oncology Group clinical trials...

HPCUT - Overview: Hematopathology Consultation, Client Embed

Obtaining a rapid, expert opinion for diagnosis of hematologic and nonhematologic diseases using bone marrow biopsy specimens referred by the primary pathologist Obtaining special studies that are not available locally

G6PD1 - Overview: Glucose 6-Phosphate Dehydrogenase Enzyme Activity, Blood

Evaluation of individuals with episodic or chronic Coombs-negative nonspherocytic hemolytic anemia Rapid testing to assess glucose 6-phosphate dehydrogenase (G6PD) enzyme capacity prior to rasburicase or other therapies that may cause...

PFN - Overview: Propafenone, Serum

Monitoring propafenone therapy Assessing potential propafenone toxicity

HK1 - Overview: Hexokinase Enzyme Activity, Blood

The evaluation of individuals with Coombs-negative chronic hemolysis

MURA - Overview: Lysozyme (Muramidase), Plasma

As a screening test for ocular sarcoidosis Confirming marked increases in the granulocyte or monocyte pools as in granulocytic or monocytic leukemias, myeloproliferative disorders, and malignant histiocytosis Following the course of...

IOD - Overview: Iodine, Serum

Determining iodine overload using serum specimens Monitoring iodine levels in individuals taking iodine-containing drugs

ABOMR - Overview: ABO/Rh, Blood

Determining blood group ABO and Rh only

OXYMU - Overview: Oxymorphone Confirmation, Random, Urine

Detection and quantification of oxymorphone and noroxymorphone in urine

TOBTA - Overview: Tobramycin, Trough, Serum

Monitoring adequate clearance of tobramycin near the end of a dosing cycle

TOBPA - Overview: Tobramycin, Peak, Serum

Monitoring adequacy of serum concentration during tobramycin therapy

CATTR - Overview: Cold Agglutinin Titer, Serum

Detection of cold agglutinins in patients with suspected cold agglutinin disease This test is not recommended to diagnose Mycoplasma pneumoniae infections.

CZPS - Overview: Clonazepam and 7-Aminoclonazepam, Serum

Assessing patient compliance Monitoring for appropriate therapeutic level Assessing clonazepam toxicity

SP7CC - Overview: Septin-7 Antibody, Cell-Binding Assay, Spinal Fluid

Detecting septin-7 IgG by cell-binding assay using cerebrospinal fluid specimens

MDNS - Overview: Methadone and Metabolites, Serum

Compliance monitoring of methadone Assessment of methadone toxicity

RPHOC - Overview: Phosphorus, Random, Urine

Evaluation of hypo- or hyperphosphatemic states Evaluation of patients with nephrolithiasis

GNSPD - Overview: Platelet Storage Pool Deficiency Gene Panel, Next-Generation Sequencing, Varies

Evaluating hereditary platelet storage pool deficiencies in patients with a personal or family history suggestive of a hereditary platelet storage pool deficiency Diagnosing hereditary platelet storage pool deficiencies for patients in...

WNMS - Overview: West Nile Virus Antibody, IgM, Serum

Detection of IgM antibodies in West Nile virus infections

BCGR - Overview: Immunoglobulin Gene Rearrangement, Blood

Determining whether a B-cell or plasma cell population is polyclonal or monoclonal using whole blood specimens Identifying neoplastic cells as having B-cell or plasma cell differentiation Monitoring for a persistent neoplasm by...

TCGBM - Overview: T-Cell Receptor Gene Rearrangement, PCR, Bone Marrow

Determining whether a T-cell population is polyclonal or monoclonal

TCGR - Overview: T-Cell Receptor Gene Rearrangement, PCR, Blood

Determining whether a T-cell population is polyclonal or monoclonal using blood specimens

CUS1 - Overview: Copper, Serum

Diagnosis of: -Wilson disease -Primary biliary cholangitis -Primary sclerosing cholangitis

HK27M - Overview: Histone H3 K27M Mutant (H3 K27M) Immunostain, Technical Component Only

Identifying the presence of altered H3 K27M protein

GDS - Overview: Gadolinium, Serum

Aiding in documenting previous exposure to gadolinium-based contrast agents using serum specimens

GDUCR - Overview: Gadolinium/Creatinine Ratio, Random, Urine

Assessing chronic exposure and monitoring effectiveness of dialysis in a random urine collection

HPFH - Overview: Hemoglobin F Distribution, Blood

Distinguishing large deletional hereditary persistence of fetal hemoglobin from other conditions with increased percentage of fetal hemoglobin (Hb F) Determining the distribution of Hb F within red blood cells

BCGBM - Overview: Immunoglobulin Gene Rearrangement, PCR, Bone Marrow

Determining whether a B-cell or plasma cell population is polyclonal or monoclonal using bone marrow specimens Identifying neoplastic cells as having B-cell or plasma cell differentiation Monitoring for a persistent neoplasm by...

LRBA - Overview: Lipopolysaccharide-Responsive Beige-Like Anchor Protein (LRBA) Deficiency, Blood

Aiding in the diagnosis of lipopolysaccharide-responsive beige-like anchor protein (LRBA) deficiency This test is not useful for identifying a carrier status for LRBA deficiency.

AERMC - Overview: Aeromonas Culture, Feces

Determining whether Aeromonas species may be the cause of diarrhea This test is generally not useful for patients hospitalized more than 3 days because the yield from specimens from these patients is very low, as is the likelihood of...

SPAS - Overview: Arsenic Speciation, Random, Urine

Diagnosing arsenic intoxication using random urine specimens

AMPHX - Overview: Amphetamines Confirmation, Chain of Custody, Random, Urine

Confirming drug exposure involving amphetamines such as amphetamine and methamphetamine, phentermine, pseudoephedrine/ephedrine, methylenedioxymethamphetamine, and methylenedioxyamphetamine. Providing chain-of-custody for when the results...

BMIYC - Overview: Borrelia miyamotoi Detection PCR, Spinal Fluid

Aids in the diagnosis of Borrelia miyamotoi infection in conjunction with clinical findings This test is not useful for detecting the Borrelia species that cause Lyme disease.

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Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights

Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....

NELL-1 [Test in Focus] - Insights

D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...

Looking Back on Clinical Chemistry 1 - Insights

in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....

Detection of (1→3)-𝝱-D-glucan as a Marker of Invasive Fungal Disease - Insights

In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections....

Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights

test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....

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