ARSBB - Overview: Arylsulfatase B, Blood Spot

Supporting the biochemical diagnosis of mucopolysaccharidosis type VI (MPS VI, Maroteaux-Lamy syndrome) This test is not useful for carrier detection for MPS VI

HSMBS - Overview: Hepatosplenomegaly Panel, Blood Spot

As a component of the initial evaluation of a patient presenting with hepatosplenomegaly, using dried blood spot specimens This test is not useful for the identification of carriers. This test should not be used as a monitoring tool for...

MSH6 - Overview: MSH6 Immunostain, Technical Component Only

Identifying patients at high risk for having hereditary nonpolyposis colorectal cancer, also known as Lynch syndrome, in an immunopanel including MSH6 and other mismatch repair markers Evaluation of tumor tissue to identify patients at...

MSH2 - Overview: MSH2 Immunostain, Technical Component Only

Identifying patients at high risk for having hereditary nonpolyposis colorectal cancer, also known as Lynch syndrome, in an immunopanel including MSH2 and other mismatch repair markers Evaluation of tumor tissue to identify patients at...

TLPMF - Overview: T-Cell Lymphoma, Specified FISH, Varies

Detecting, at diagnosis, common chromosome abnormalities associated with specific T-cell lymphoma subtypes using client specified probes

BIWB - Overview: Bismuth, Blood

Determining bismuth toxicity

HGCU - Overview: Mercury/Creatinine Ratio, Random, Urine

Detecting mercury toxicity using random urine specimens

UPHB - Overview: pH, Body Fluid

Indicating the presence of infections or fistulas Verifying the effectiveness of treatment to reduce stomach pH Diagnosing disease states characterized by abnormal stomach acidity This test is not appropriate for measurement of...

FLEC - Overview: Flecainide, Serum

Optimizing flecainide dosage Assessing flecainide toxicity Monitoring compliance

FIBAG - Overview: Fibrinogen Antigen, Plasma

Evaluation of fibrinogen deficiency Measuring fibrinogen in patients with elevated plasma levels of fibrin degradation products, patients receiving heparin, and in patients with antibodies to thrombin (following surgical use of topical...

GD65C - Overview: Glutamic Acid Decarboxylase (GAD65) Antibody Assay, Spinal Fluid

Possible use in evaluating patients with autoimmune encephalitis, stiff-person syndrome, autoimmune ataxia, autoimmune epilepsy, and other acquired central nervous system disorders affecting gabaminergic neurotransmission

MEX - Overview: Mexiletine, Serum

Assessing achievement of optimal therapeutic mexiletine concentrations Assessing potential mexiletine toxicity

PENTS - Overview: Pentobarbital, Serum

Monitoring of pentobarbital therapy treatment

PQNRU - Overview: Porphyrins, Quantitative, Random, Urine

Preferred test to begin assessment for congenital erythropoietic porphyria and porphyria cutanea tarda and during symptomatic periods for acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria when specimen...

TLPDF - Overview: T-Cell Lymphoma, Diagnostic FISH, Varies

Detecting, at diagnosis, common chromosome abnormalities associated with specific T-cell lymphoma subtypes using a laboratory-designated probe set algorithm

SHBG1 - Overview: Sex Hormone-Binding Globulin, Serum

Diagnosis and follow-up of women with signs or symptoms of androgen excess (eg, polycystic ovarian syndrome and idiopathic hirsutism) An adjunct in monitoring sex-steroid and antiandrogen therapy An adjunct in the diagnosis of disorders...

ADMA - Overview: Asymmetric Dimethylarginine, Plasma

Assessing the likelihood of future coronary events in patients with coronary heart disease, type II diabetes mellitus, or kidney disease Prompting intervention and assessing improvements among subjects with elevated ADMA and...

CURCU - Overview: Copper/Creatinine Ratio, Random, Urine

Investigation of Wilson disease and obstructive liver disease using a random urine specimen

GRH - Overview: Growth Hormone Immunostain, Technical Component Only

Aids in the identification of growth hormone adenomas

HGU - Overview: Mercury, 24 Hour, Urine

Detecting mercury toxicity using 24-hour urine specimens

P62 - Overview: p62 Immunostain, Technical Component Only

Aids in diagnosing argyrophilic grain disease

LAMO - Overview: Lamotrigine, Serum

Monitoring serum concentration of lamotrigine Assessing compliance Adjusting lamotrigine dose in patients receiving other anticonvulsant drugs that interact pharmacokinetically with lamotrigine

HGUOE - Overview: Mercury Occupational Exposure, Random, Urine

Detecting mercury toxicity due to occupational exposure

MUSK - Overview: Muscle-Specific Kinase (MuSK) Autoantibody, Serum

Diagnosis of autoimmune muscle-specific kinase (MuSK) myasthenia gravis Second-order test to aid in the diagnosis of autoimmune myasthenia gravis when first-line serologic tests are negative Establishing a quantitative baseline value...

SOMAT - Overview: Somatostatin Immunostain, Technical Component Only

Aids in the characterization of pancreatic islet cell tumors or other neuroendocrine tumors

TRPS - Overview: Troponin T, 5th Generation, Plasma

Aiding in the exclusion of the diagnosis of acute coronary syndrome in a single plasma specimen Aiding in the diagnosis of acute coronary syndrome Monitoring acute coronary syndromes and estimating prognosis Possible utility in...

AMPHU - Overview: Amphetamines Confirmation, Random, Urine

Confirming drug exposure involving amphetamines such as amphetamine and methamphetamine, phentermine, pseudoephedrine/ephedrine, methylenedioxyamphetamine (MDA), and methylenedioxymethamphetamine (MDMA)

AMIO - Overview: Amiodarone, Serum

Monitoring amiodarone therapy, especially when amiodarone is coadministered with other drugs that may interact Evaluating possible amiodarone toxicity Assessing patient compliance

INTAD - Overview: Adalimumab Panel, Interpretation

Interpretation of therapeutic drug monitoring of adalimumab concentration and antibody levels

PMSBB - Overview: Postmortem Screening, Bile and Blood Spot

Postmortem evaluation of individuals at any age who died suddenly or unexpectedly; testing is particularly recommended under the following circumstances (risk factors): -Family history of sudden infant death syndrome or other sudden...

PQNU - Overview: Porphyrins, Quantitative, 24 Hour, Urine

Preferred screening test for congenital erythropoietic porphyria and porphyria cutanea tarda and during symptomatic periods for acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria when specimen transport will be...

G6PDC - Overview: Glucose 6 Phosphate Dehydrogenase Enzyme Activity, Blood

Evaluation of individuals with episodic or chronic Coombs-negative nonspherocytic hemolytic anemia Rapid testing to assess glucose-6-phosphate dehydrogenase (G6PD) enzyme capacity prior to rasburicase or other therapies that may cause...

B2M - Overview: Beta-2-Microglobulin, Serum

Prognosis assessment of multiple myeloma Evaluation of renal tubular disorders

COBRU - Overview: Cobalt/Creatinine Ratio, Random, Urine

Detecting cobalt exposure in a random urine collection Monitoring metallic prosthetic implant wear This test is not useful for assessment of vitamin B12 activity.

COU - Overview: Cobalt, 24 Hour, Urine

Detecting cobalt exposure Monitoring metallic prosthetic implant wear This test is not useful to assess vitamin B12 activity.

GD65S - Overview: Glutamic Acid Decarboxylase (GAD65) Antibody Assay, Serum

Assessing susceptibility to autoimmune (type 1, insulin-dependent) diabetes mellitus and related endocrine disorders (eg, thyroiditis and pernicious anemia) Distinguishing between patients with type 1 and type 2 diabetes Confirming a...

HVAR - Overview: Homovanillic Acid, Random, Urine

Screening children for catecholamine-secreting tumors using a random urine collection when requesting homovanillic acid only Monitoring neuroblastoma treatment Screening patients with possible inborn errors of catecholamine metabolism

CCPQ - Overview: P/Q-Type Calcium Channel Antibody, Serum

Confirming a diagnosis of Lambert-Eaton syndrome Implicating autoimmunity as a disease-causing mechanism in patients with complex neurologic presentations, particularly in those with a history of cancer Implicating autoimmunity as the...

CUT - Overview: Copper, Liver Tissue

Diagnosing Wilson disease and primary biliary cirrhosis using liver tissue specimens

CARFT - Overview: Carbamazepine, Free and Total, Serum

Monitoring carbamazepine (free and total) therapy in patients who are uremic

CARF - Overview: Carbamazepine, Free, Serum

Monitoring unbound or free carbamazepine levels in patients where the total carbamazepine result is within the therapeutic range, but the patient is experiencing side effects Monitoring carbamazepine (free) therapy in patients who are...

SGSS - Overview: Synthetic Glucocorticoid Screen, Serum

Confirming the presence of listed synthetic glucocorticoids (see Interpretation) Confirming the cause of secondary adrenal insufficiency This test is not useful for detection of fluticasone propionate.

SGSU - Overview: Synthetic Glucocorticoid Screen, Random, Urine

Confirming the presence of the listed synthetic glucocorticoids Confirming the cause of secondary adrenal insufficiency

VMAR - Overview: Vanillylmandelic Acid, Random, Urine

Screening children for catecholamine-secreting tumors using a random urine collection when requesting vanillylmandelic acid only Supporting a diagnosis of neuroblastoma Monitoring patients with a treated neuroblastoma

OROT - Overview: Orotic Acid, Random, Urine

Evaluation of the differential diagnosis of hyperammonemia and hereditary orotic aciduria Sensitive indicator of ornithine transcarbamylase (OTC) activity after administration of allopurinol or a protein load to identify OTC carriers

ABADL - Overview: Adalimumab Antibody, Serum

Therapeutic drug monitoring of adalimumab antibody levels

QNADL - Overview: Adalimumab Quantitative, Serum

Therapeutic drug monitoring of adalimumab concentration

ADALX - Overview: Adalimumab Quantitative with Reflex to Antibody, Serum

Therapeutic drug monitoring of adalimumab concentration and antibody levels, if appropriate

HVPPS - Overview: HIV-1 and HIV-2 Antibody Confirmation and Differentiation Prenatal, Serum

Confirmation and differentiation of HIV-1 and HIV-2 antibodies in serum specimens from prenatal patients who show reactive results with 3rd- (HIV-1/-2 antibody only) and 4th-generation (HIV antigen and antibody) HIV serologic assays This...

IGFB3 - Overview: Insulin-Like Growth Factor-Binding Protein 3, Serum

Diagnosing growth disorders Diagnosing adult growth hormone deficiency Monitoring of recombinant human growth hormone treatment As a possible adjunct to insulin-like growth factor 1 and growth hormone in the diagnosis and follow-up of...