HGNA - Overview: Mercury, Nails

Detecting mercury exposure in nail specimens

APOL1 - Overview: APOL1 Genotype, Varies

Determining an individual's APOL1 genotype This test is not useful for clinical management of individuals with APOL1 risk genotypes. This test alone is not useful for determining eligibility for donation or receipt of kidney...

HIVDS - Overview: HIV-1 and HIV-2 Antigen and Antibody Diagnostic Evaluation, Serum

Detecting HIV-1 and HIV-2 infection in symptomatic patients older than 2 years Follow-up testing of symptomatic individuals with reactive rapid HIV test results This test should not be used as a screening or confirmatory test for blood...

THYRP - Overview: Hereditary Thyroid Cancer Panel, Varies

Evaluating patients with a personal or family history suggestive of a hereditary thyroid cancer syndrome Establishing a diagnosis of a hereditary thyroid cancer syndrome, allowing for targeted surveillance based on associated...

H2BR - Overview: HER2 Amplification Associated with Breast Cancer, FISH, Tissue

A predictive marker for patients with both node-positive or node-negative primary and metastatic breast cancer Patients with HER2 amplification that may be candidates for therapies targeting the human epidermal growth factor receptor 2...

HVCOP - Overview: HIV-1 and HIV-2 Antigen and Antibody Routine Screen, Plasma

Screening for HIV-1 and HIV-2 infection in nonsymptomatic, nonpregnant individuals older than 2 years This test should not be used as a screening or confirmatory test for blood donor specimens.

PHI11 - Overview: Prostate Health Index Reflex, Serum

As an aid in distinguishing prostate cancer from benign prostatic conditions in men aged 50 years and older with total PSA between 4.0 and 10.0 ng/mL and digital rectal examination findings that are not suspicious for cancer

NCYB - Overview: Recessive Congenital Methemoglobinemia, CYB5 and CYB5 Reductase Genetic Analysis, Next-Generation Sequencing, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of recessive congenital methemoglobinemia Genotype confirmation of borderline cytochrome b5 reductase (methemoglobin reductase: METR) enzyme activity...

DRV1 - Overview: Dilute Russell's Viper Venom Time (DRVVT), Plasma

Detecting and confirming or helping to exclude the presence of lupus anticoagulants (LA) Identifying LA that do not prolong the activated partial thromboplastin time (APTT) Evaluating unexplained prolongation of the APTT or prothrombin...

DRVI1 - Overview: Dilute Russell's Viper Venom Time (DRVVT), with Reflex, Plasma

Detecting and confirming or helping to exclude the presence of lupus anticoagulants (LA) Identifying LA that do not prolong the activated partial thromboplastin time (APTT) Evaluating unexplained prolongation of the APTT or prothrombin...

G6PD1 - Overview: Glucose 6-Phosphate Dehydrogenase Enzyme Activity, Blood

Evaluation of individuals with episodic or chronic Coombs-negative nonspherocytic hemolytic anemia Rapid testing to assess glucose 6-phosphate dehydrogenase (G6PD) enzyme capacity prior to rasburicase or other therapies that may cause...

LYNCP - Overview: Lynch Syndrome Panel, Varies

Establishing a diagnosis of Lynch syndrome or constitutional mismatch repair deficiency allowing for targeted cancer surveillance based on associated risks Identifying MLH1, MSH2, MSH6, PMS2, or EPCAM variants to allow for predictive...

MPSWB - Overview: Mucopolysaccharidosis, Blood

Supporting the biochemical diagnosis of mucopolysaccharidoses type I, II, III, IV, or VI Quantification of heparan sulfate, dermatan sulfate, and keratan sulfate in whole blood specimens

MPSBS - Overview: Mucopolysaccharidosis, Blood Spot

Supporting the biochemical diagnosis of mucopolysaccharidoses types I, II, III, IV, or VI Quantification of heparan sulfate, dermatan sulfate, and keratan sulfate in dried blood spot specimens

ASNA - Overview: Arsenic, Nails

Detection of nonacute arsenic exposure in nail specimens

HGHAR - Overview: Mercury, Hair

Detecting mercury exposure in hair specimens

PBNA - Overview: Lead, Nails

Detecting lead exposure using nail specimens

HGOU - Overview: Mercury Occupational Exposure, Random, Urine

Detecting mercury toxicity due to occupational exposure in random urine specimens

ASHA - Overview: Arsenic, Hair

Detection of nonacute arsenic exposure in hair specimens

IOD - Overview: Iodine, Serum

Determining iodine overload using serum specimens Monitoring iodine levels in individuals taking iodine-containing drugs

CZPS - Overview: Clonazepam and 7-Aminoclonazepam, Serum

Assessing patient compliance Monitoring for appropriate therapeutic level Assessing clonazepam toxicity

CDP - Overview: Chlordiazepoxide and Metabolite, Serum

Monitoring chlordiazepoxide therapy Assessing toxicity

CDOMB - Overview: Cadmium for Occupational Monitoring, Blood

Detecting exposure to cadmium, a toxic heavy metal, as a part of occupational monitoring

MDNS - Overview: Methadone and Metabolites, Serum

Compliance monitoring of methadone Assessment of methadone toxicity

QUIN - Overview: Quinidine, Serum

Assessing and adjusting quinidine dosage for optimal therapeutic level Assessing quinidine toxicity

PERAM - Overview: Perampanel, Serum

Monitoring serum concentration of perampanel, in specific clinical conditions (ie, severe kidney impairment, mild to moderate hepatic impairment, and end-stage kidney disease) Assessing compliance Assessing potential toxicity

SEWB - Overview: Selenium, Blood

Assessment of tissue stores of selenium

CDB - Overview: Cadmium, Blood

Detecting exposure to cadmium, a toxic heavy metal

DIA - Overview: Diazepam and Nordiazepam, Serum

Assessing compliance Monitoring for appropriate therapeutic level Assessing diazepam toxicity

PBHA - Overview: Lead, Hair

Detecting lead exposure using hair specimens

PBOU - Overview: Lead Occupational Exposure, Random, Urine

Detecting clinically significant lead exposure due to occupational exposure in random urine specimens This test is not a substitute for blood lead screening.

TRSF - Overview: Transferrin, Serum

Evaluation of iron overload diseases Evaluation of iron deficiency as a cause of anemia

ETGL - Overview: Ethylene Glycol, Serum

Confirming and monitoring ethylene glycol toxicity

HMDB - Overview: Heavy Metals Screen with Demographics, Blood

Detecting exposure to arsenic, lead, cadmium, and mercury

CFSMN - Overview: Cystic Fibrosis and Spinal Muscular Atrophy Carrier Screen Panel, Varies

Reproductive risk refinement via carrier screening for individuals in the general population for cystic fibrosis (CF) and spinal muscular atrophy (SMA). Reproductive risk refinement via carrier screening for individuals with a family...

BRTP - Overview: Rapid Hereditary Breast Cancer Treatment Decision Panel, Varies

Establishing a diagnosis of a hereditary breast cancer syndrome allowing for surgical and management decision making Determining therapeutic eligibility with poly (adenosine diphosphate-ribose) polymerase inhibitors based on certain gene...

MCSRC - Overview: MayoComplete Comprehensive Sarcoma Panel, Next-Generation Sequencing, Tumor

Primarily for identifying mutations that help in the diagnosis of specific soft tissue and bone tumors (sarcoma) Secondarily for identifying mutations that have therapeutic or prognostic significance Assessing microsatellite instability...

MPSQU - Overview: Mucopolysaccharides Quantitative, Random, Urine

Supporting the biochemical diagnosis of one of the mucopolysaccharidoses: types I, II, III, IV, VI, or VII

BIWB - Overview: Bismuth, Blood

Determining bismuth toxicity

BRUTA - Overview: Brucella Total Antibody Confirmation, Agglutination, Serum

Diagnosis of brucellosis

CLD18 - Overview: Claudin 18 (CLDN18) (43-14A), Semi-Quantitative Immunohistochemistry, Manual

Identification of tumor cells expressing claudin 18 As an aid in screening patients who may be eligible for VYLOY (zolbetuximab) treatment

HYDMU - Overview: Hydromorphone Confirmation, Random, Urine

Detection and quantification of hydromorphone in urine

HYDCU - Overview: Hydrocodone with Metabolite Confirmation, Random, Urine

Detection and quantification of hydrocodone, norhydrocodone, and hydromorphone in urine

ITCON - Overview: Itraconazole, Serum

Verifying systemic absorption of orally administered itraconazole Patients with life-threatening fungal infections Patients considered at risk for poor absorption or rapid clearance of itraconazole

GABA - Overview: Gabapentin, Serum

Monitoring serum gabapentin concentrations Assessing compliance Adjusting dosage in patients

NOTRP - Overview: Nortriptyline, Serum

Monitoring nortriptyline concentration during therapy Evaluating potential nortriptyline toxicity May aid in evaluating patient compliance

HGCU - Overview: Mercury/Creatinine Ratio, Random, Urine

Detecting mercury toxicity using random urine specimens

POSA - Overview: Posaconazole, Serum

Monitoring posaconazole therapy

PINW - Overview: Pinworm Exam, Perianal

Detection of the eggs of Enterobius vermicularis on the skin of the perianal folds

PFN - Overview: Propafenone, Serum

Monitoring propafenone therapy Assessing potential propafenone toxicity