CLD18 - Overview: Claudin 18 (CLDN18) (43-14A), Semi-Quantitative Immunohistochemistry, Manual
Identification of tumor cells expressing claudin 18 As an aid in screening patients who may be eligible for VYLOY (zolbetuximab) treatment
BFCC - Overview: Cell Count and Differential, Body Fluid
Aiding in the diagnosis of joint disease, systemic disease, inflammation, malignancy, infection, and trauma
C3 - Overview: Complement C3, Serum
Assessing disease activity in systemic lupus erythematosus Investigating an undetectable total complement level
C4 - Overview: Complement C4, Serum
Investigating an undetectable total complement Confirming hereditary angioedema (with low C1 inhibitor) Assessing disease activity in systemic lupus erythematosus, proliferative glomerulonephritis, rheumatoid arthritis, and autoimmune...
PLA2M - Overview: Phospholipase A2 Receptor, Monitoring, Enzyme-Linked Immunosorbent Assay, Serum
Distinguishing primary from secondary membranous nephropathy Monitoring patients with membranous nephropathy, over time, for trends in anti-phospholipase A2 receptor antibody levels
MSTC - Overview: Strict Criteria Sperm Morphology for Infertility Diagnosis and Treatment, Semen
Diagnosing male infertility Selecting the most cost-effective therapy for treating male-factor infertility Quantifying the number of germinal and white blood cells per mL of semen
SPNC - Overview: Streptococcus pneumoniae Antigen, Spinal Fluid
Rapid diagnosis of pneumococcal meningitis
CD2B - Overview: CD2 Immunostain, Bone Marrow, Technical Component Only
Determining T-cell lineage
C19BM - Overview: CD19 Immunostain, Bone Marrow, Technical Component Only
Identification of normal and neoplastic B cells
CXC13 - Overview: CXCL13 Immunostain, Technical Component Only
Assessment of CXCL13 (CXC motif chemokine ligand 13) expression
CHOL - Overview: Cholesterol, Total, Serum
Evaluation of cardiovascular risk
CDX2 - Overview: CDX2 Immunostain, Technical Component Only
Identification of carcinoma of intestinal origin
DSAC - Overview: Disaccharidase Activity Panel, Tissue
Evaluation of patients who present with signs or symptoms suggestive of disaccharidase disorders This test is not intended for carrier detection.
CBSRP - Overview: Coxiella burnetii (Q Fever), Molecular Detection, PCR, Serum
Aiding in the diagnosis of Coxiella burnetii infection (ie, Q fever) using serum specimens
CD15 - Overview: CD15 Immunostain, Technical Component Only
Phenotyping leukemias and lymphomas
CLDL1 - Overview: Cholesterol, Low-Density Lipoprotein (LDL), Calculated, Serum
Calculation of low-density lipoprotein cholesterol using total cholesterol, non-high-density lipoprotein (HDL) cholesterol, HDL cholesterol, and triglyceride concentrations Managing atherosclerotic cardiovascular disease risk
EVROL - Overview: Everolimus, Blood
Managing everolimus immunosuppression in solid organ transplant
F9_IS - Overview: Factor IX Inhibitor Screen, Plasma
Detecting the presence of a specific factor inhibitor directed against coagulation factor IX
F_7 - Overview: Coagulation Factor VII Activity Assay, Plasma
Diagnosing congenital deficiency of coagulation factor VII Evaluating acquired deficiencies associated with liver disease, oral anticoagulant therapy, and vitamin K deficiency Determining degree of anticoagulation with warfarin to...
WNVSI - Overview: West Nile Serum Interpretation
Interpretation of testing for a laboratory diagnosis of infection with West Nile virus
WNVCI - Overview: West Nile CSF Interpretation
Interpretation of testing for a laboratory diagnosis of infection with West Nile virus using spinal fluid specimens Aids in diagnosis of central nervous system infection with West Nile virus
EEPC - Overview: Eastern Equine Encephalitis Antibody Panel, IgG and IgM, Spinal Fluid
Aiding in the diagnosis of Eastern equine encephalitis using spinal fluid specimens
KRTOS - Overview: Keratin (OSCAR) Immunostain, Technical Component Only
Aids in determining primary site in carcinomas of unknown origin
PRCON - Overview: Protein, Total, Random, Urine
Measurement of total protein for the assessment of orthostatic proteinuria
FVAG - Overview: Fungal Culture, Vaginal
Monitoring therapy for vulvovaginitis Managing chronic recurring disease Determining the etiology of infectious vaginitis when other tests have been uninformative
MET - Overview: Methemoglobin and Sulfhemoglobin, Blood
Diagnosing methemoglobinemia and sulfhemoglobinemia Identifying cyanosis due to other causes, such as congenital heart disease
ZW298 - Overview: Miscellaneous IntrinsicDx
Miscellaneous IntrinsicDx
FSFM - Overview: Soluble Fibrin Monomer
Soluble Fibrin Monomer
ZW143 - Overview: Miscellaneous IMMCO Diagnostics
Miscellaneous IMMCO Diagnostics
PTP - Overview: Porphyrins, Total, Plasma
Monitoring treatment of patients with porphyria cutanea tarda
HBCRQ - Overview: Hepatitis B Virus Core-Related Antigen, Quantitative, Serum
Monitoring of response to antiviral therapy in individuals with chronic hepatitis B who are negative for hepatitis B e antigen (HBeAg), positive for hepatitis B e antibody, and undetectable or low hepatitis B virus DNA levels (eg, <500...
GALCW - Overview: Galactocerebrosidase, Leukocytes
Diagnosis of Krabbe disease Follow-up testing for evaluation of an abnormal newborn screening result for Krabbe disease This test is not intended for carrier detection.
MRSAP - Overview: Methicillin Resistant Staphylococcus aureus, PCR, Nasal
Rapid screening test for Staphylococcus aureus nasal carriage that, if positive, indicates whether the S aureus is methicillin susceptible or resistant This test should not be used to guide or monitor treatment for methicillin-resistant S...
NSE - Overview: Neuron-Specific Enolase, Serum
A follow-up marker in patients with neuron-specific enolase-secreting tumors of any type An auxiliary test in the diagnosis of small cell lung carcinoma An auxiliary test in the diagnosis of carcinoids, islet cell tumors, and...
Detecting Chlamydia trachomatis and Neisseria gonorrhoeae using a throat swab collected by the patient in a healthcare setting This test is not intended for use in medico-legal applications. This test is not useful for the detection of...
Detecting Chlamydia trachomatis and Neisseria gonorrhoeae using self-collected vaginal swabs collected by the patient in a healthcare setting This test is not intended for use in medico-legal applications. This test is not useful for the...
CHRHB - Overview: Chromosome Analysis, Hematologic Disorders, Blood
Assisting in the classification and follow-up of certain malignant hematological disorders when bone marrow is not available This test is not useful for congenital disorders.
EPO - Overview: Erythropoietin, Serum
An aid in distinguishing between primary and secondary polycythemia Differentiating between appropriate secondary polycythemia (eg, high-altitude living, pulmonary disease, tobacco use) and inappropriate secondary polycythemia (eg,...
P53CA - Overview: Hematologic Neoplasms, TP53 Somatic Mutation, DNA Sequencing Exons 4-9, Varies
Evaluating chronic lymphocytic leukemia patients at diagnosis or during disease course for the presence of TP53 gene variants indicating high risk of disease progression and adverse outcomes This test is not intended for the evaluation of...
Detecting Chlamydia trachomatis and Neisseria gonorrhoeae using rectal swabs collected by the patient in a healthcare setting This test is not intended for use in medico-legal applications. This test is not useful for the detection of...
CRCGP - Overview: Hereditary Gastrointestinal Cancer Panel, Varies
Evaluating patients with a personal or family history suggestive of a hereditary gastrointestinal cancer or hereditary polyposis syndrome Establishing a diagnosis of a hereditary gastrointestinal cancer syndrome or hereditary polyposis...
HCVDR - Overview: Hepatitis C Virus Genotypic Antiviral Drug Resistance, Serum
Detecting and identifying codon substitutions in the hepatitis C virus (HCV) NS3, NS5A, and NS5B genomic regions that confer resistance to current direct-acting antiviral drugs used for treatment of chronic hepatitis C infection due to HCV...
THYRP - Overview: Hereditary Thyroid Cancer Panel, Varies
Evaluating patients with a personal or family history suggestive of a hereditary thyroid cancer syndrome Establishing a diagnosis of a hereditary thyroid cancer syndrome, allowing for targeted surveillance based on associated...
BRTP - Overview: Rapid Hereditary Breast Cancer Treatment Decision Panel, Varies
Establishing a diagnosis of a hereditary breast cancer syndrome allowing for surgical and management decision making Determining therapeutic eligibility with poly (adenosine diphosphate-ribose) polymerase inhibitors based on certain gene...
GIP - Overview: Gastrointestinal Pathogen Panel, PCR, Feces
Rapid detection of gastrointestinal infections caused by: -Campylobacter species (Campylobacter jejuni/Campylobacter coli/Campylobacter upsaliensis) -Clostridioides difficile toxin A/B -Plesiomonas shigelloides -Salmonella species -Vibrio...
CMITO - Overview: Combined Mitochondrial Full Genome and Nuclear Gene Panel, Varies
Diagnosing mitochondrial disease that results from variants in either nuclear-encoded genes or the mitochondrial genome A second-tier test for patients in whom previous targeted gene variant analyses for specific mitochondrial...
RENCP - Overview: Hereditary Renal Cancer Panel, Varies
Evaluating patients with a personal or family history suggestive of a hereditary renal cancer syndrome Establishing a diagnosis of a hereditary renal cancer syndrome allowing for targeted cancer surveillance based on associated risks...
HEMP - Overview: Hereditary Erythrocytosis Mutations, Whole Blood
Definitive evaluation of an individual with JAK2-negative erythrocytosis associated with lifelong sustained increased red blood cell (RBC) mass, elevated RBC count, hemoglobin, or hematocrit This test is not intended for prenatal...
LQTSG - Overview: Long QT Syndrome Gene Panel, Varies
Providing a genetic evaluation for patients with a personal or family history suggestive of long QT syndrome (LQTS) Establishing a diagnosis of LQTS
Evaluation of pediatric bone marrow specimens for chromosomal abnormalities associated with hematologic malignancies for diagnostic and prognostic purposes in patients being considered for enrollment in Children's Oncology Group clinical...
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Detection of (1→3)-𝝱-D-glucan as a Marker of Invasive Fungal Disease - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....