CIMRP - Overview: Coccidioides immitis/posadasii, Molecular Detection, PCR, Varies

Rapid detection of Coccidioides DNA, preferred method An aid in diagnosing coccidioidomycosis

FACTV - Overview: Coagulation Factor V Activity Assay, Plasma

Diagnosing congenital deficiencies (rare) of coagulation factor V Evaluating acquired deficiencies associated with liver disease, factor V inhibitors, myeloproliferative disorders, and intravascular coagulation and fibrinolysis...

B2M - Overview: Beta-2-Microglobulin, Serum

Prognosis assessment of multiple myeloma Evaluation of renal tubular disorders

BILIT - Overview: Bilirubin, Total, Serum

Assessing liver function Evaluating a wide range of diseases affecting the production, uptake, storage, metabolism, or excretion of bilirubin Monitoring the efficacy of neonatal phototherapy

BAP - Overview: Bone Alkaline Phosphatase, Serum

Diagnosis and assessment of severity of metabolic bone disease including Paget disease, osteomalacia, and other states of high bone turnover Monitoring efficacy of antiresorptive therapies including postmenopausal osteoporosis treatment...

CEE20 - Overview: CD20 Cell Expression Evaluation, Varies

Detecting cell-surface antigens on malignant cells that are potential therapeutic antibody targets, specifically CD20 Determining the eligibility of patients for monoclonal antibody therapies Monitoring response to the therapeutic...

COXIS - Overview: Coccidioides Antibody Screen with Reflex, Serum

Detecting antibodies to Coccidioides immitis/posadasii This assay should not be used for monitoring response to therapy.

CLZ - Overview: Clozapine, Serum

Monitoring patient compliance of clozapine treatment An aid to achieving desired serum levels

CYSQN - Overview: Cystinuria Profile, Quantitative, 24 Hour, Urine

Diagnosis of cystinuria using 24-hour urine collections

CARNU - Overview: Carnitine, Random, Urine

Evaluation of patients with a clinical suspicion of a wide range of conditions including organic acidemias and fatty acid oxidation disorders Monitoring carnitine treatment

RSCOC - Overview: Coccidioides Antibody Reflex, Complement Fixation and Immunodiffusion, Serum

Detection of antibodies to Coccidioides species

C4FX - Overview: C4 Complement, Functional, Serum

Diagnosis of C4 deficiency Investigation of a patient with an undetectable total complement level

FCDSU - Overview: Comprehensive Drug Screen, Umbilical Cord Tissue

Comprehensive Drug Screen, Umbilical Cord Tissue

CALU - Overview: Calcium, 24 Hour, Urine

Evaluation of calcium oxalate and calcium phosphate kidney stone risk, and calculation of urinary supersaturation Evaluation of bone diseases, including osteoporosis and osteomalacia

CACR3 - Overview: Calcium/Creatinine Ratio, Random, Urine

Evaluation of calcium oxalate and calcium phosphate kidney stone risk Calculation of urinary supersaturation Evaluation of bone diseases, including osteoporosis and osteomalacia

CEE49 - Overview: CD49d Cell Expression Evaluation, Varies

Detecting cell-surface antigens on malignant cells that are potential therapeutic antibody targets, specifically CD49d Determining the eligibility of patients for monoclonal antibody therapies Monitoring response to the therapeutic...

CHLM - Overview: Chlamydia IgM, Immunofluorescence, Serum

Assessing IgM antibody levels to aid in the clinical diagnosis of Chlamydia pneumoniae or Chlamydia psittaci infections

EEEP - Overview: Eastern Equine Encephalitis Antibody, IgG and IgM, Serum

Aiding in the diagnosis of Eastern equine encephalitis using serum specimens

ECULI - Overview: Eculizumab, Serum

Assessing the response to eculizumab therapy Assessing the need for dose escalation Evaluating the potential for dose de-escalation or discontinuation of therapy in remission states Monitoring patients who need to be above a certain...

HERGN - Overview: HER2, Gastric/Esophageal, Semi-Quantitative Immunohistochemistry, Manual, No Reflex

Determining overexpression of HER2 protein of gastric and esophageal adenocarcinoma in formalin-fixed, paraffin-embedded tissue sections (no reflex to FISH testing)

HCQ - Overview: Hydroxychloroquine, Serum

Monitoring serum hydroxychloroquine concentrations, assessing compliance, and adjusting dosage in patients

HERDN - Overview: HER2, Breast, DCIS, Quantitative Immunohistochemistry, Manual No Reflex

Determining overexpression of HER2 protein on formalin-fixed, paraffin-embedded tissue sections in ductal carcinoma in situ or solid/intracystic papillary carcinoma breast tissue This FDA-approved test is most frequently used to evaluate...

HVAR - Overview: Homovanillic Acid, Random, Urine

Screening children for catecholamine-secreting tumors using a random urine collection when requesting homovanillic acid only Monitoring neuroblastoma treatment Screening patients with possible inborn errors of catecholamine metabolism

HISME - Overview: Histone H3 Trimethyl K27 Immunostain, Technical Component Only

Diagnosis of malignant peripheral nerve sheath tumors and diffuse midline gliomas H3 K27M-mutant

IL5P - Overview: Interleukin 5, Plasma

Evaluation of patients with disorders known to be associated with hypereosinophilia

UIOD - Overview: Iodine, 24 Hour, Urine

Assessing iodine toxicity or recent exposure in a 24-hour urine collection Monitoring iodine excretion rate as index of replacement therapy

HEMMF - Overview: Hematologic Specified FISH, Varies

The detection of specific chromosomal abnormalities in hematologic malignancies

KIDST - Overview: Kidney Stone Analysis

Managing patients with recurrent renal calculi (kidney stones)

MSMN - Overview: Membranous Nephropathy Target Antigen Identification, Mass Spectrometry, Tissue

Identification of antigen in membranous nephropathy

BFLA1 - Overview: Lipid Analysis, Body Fluid

Distinguishing between chylous and nonchylous effusions

LDLD - Overview: Low-Density Lipoprotein (LDL) Cholesterol, Beta-Quantification, Serum

Evaluation of cardiovascular risk Verification of estimated low-density lipoprotein cholesterol (LDL-C) in patients with hypertriglyceridemia or extremely low LDL-C Diagnosis of familial hypobetalipoproteinemia and abetalipoproteinemia

LEPDT - Overview: Leptospira, IgM, Serum

Aiding in the diagnosis of leptospirosis This test is not useful for establishing cure or response to therapy.

BCGBM - Overview: Immunoglobulin Gene Rearrangement, PCR, Bone Marrow

Determining whether a B-cell or plasma cell population is polyclonal or monoclonal using bone marrow specimens Identifying neoplastic cells as having B-cell or plasma cell differentiation Monitoring for a persistent neoplasm by...

IA2 - Overview: Islet Antigen 2 (IA-2) Antibody, Serum

Clinical distinction of type 1 from type 2 diabetes mellitus Identification of individuals at risk of type 1 diabetes (including high-risk relatives of patients with diabetes) Prediction of future need for insulin treatment in...

KI67 - Overview: Ki-67 (MIB-1) Immunostain, Technical Component Only

A marker of proliferation in neoplasms

PBU - Overview: Lead, 24 Hour, Urine

Detecting clinically significant lead exposure in 24-hour specimens This test is not a substitute for blood lead screening.

PBUCR - Overview: Lead/Creatinine Ratio, Random, Urine

Detecting clinically significant lead exposure, a toxic heavy metal, using random urine specimens

LALB - Overview: Lysosomal Acid Lipase, Blood

Evaluation of patients with a clinical presentation suggestive of lysosomal acid lipase deficiency using blood specimens This test is not useful to determine carrier status for cholesteryl ester storage disease or Wolman disease.

SLEG - Overview: Legionella pneumophila (Legionnaires Disease), Antibody, Serum

Evaluating possible legionellosis (Legionnaires disease, Pontiac fever, extrapulmonary legionella infection caused by Legionella pneumophila)

MTDNU - Overview: Methadone Confirmation, Random, Urine

Monitoring for compliance of methadone treatment for analgesia or drug rehabilitation Assessing compliance with rehabilitation programs by urine measurement of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine

HMHA - Overview: Heavy Metals, Hair

Detection of nonacute arsenic, mercury, and lead exposure using hair specimens

IODCU - Overview: Iodine/Creatinine Ratio, Random, Urine

Assessment of iodine toxicity or recent iodine exposure using a random urine collection Monitoring iodine excretion rate as index of replacement therapy

BCGR - Overview: Immunoglobulin Gene Rearrangement, Blood

Determining whether a B-cell or plasma cell population is polyclonal or monoclonal using whole blood specimens Identifying neoplastic cells as having B-cell or plasma cell differentiation Monitoring for a persistent neoplasm by...

AHDV - Overview: Hepatitis D Virus Total Antibodies, Serum

Detection of hepatitis D virus (HDV)-specific total antibodies (combined IgG and IgM) in human serum Diagnosis of concurrent HDV infection in patients with fulminant acute hepatitis B virus (HBV) infection (acute coinfection), chronic HBV...

IGE - Overview: Immunoglobulin E (IgE), Serum

Evaluating patients with suspected diseases associated with elevations in total immunoglobulin E (IgE), including allergic disease, primary immunodeficiencies, infections, malignancies, or other inflammatory diseases Diagnostic evaluation...

INSFT - Overview: Insulin, Free and Total, Serum

Assessing free (bioactive) insulin concentrations in patients with known or suspected anti-insulin antibodies

LH - Overview: Luteinizing Hormone (LH), Serum

An adjunct in the evaluation of menstrual irregularities Evaluating patients with suspected hypogonadism Predicting ovulation Evaluating infertility Diagnosing pituitary disorders

FATF - Overview: Fat, Feces

Diagnosing fat malabsorption due to pancreatic or intestinal disorders Monitoring effectiveness of enzyme supplementation in certain malabsorption disorders This test is not useful for differentiating among pancreatic diseases.

FIL - Overview: Filaria, Blood

Detecting microfilariae in peripheral blood

LGBBS - Overview: Globotriaosylsphingosine, Blood Spot

Screening of patients with Fabry disease using dried blood spots when a serum specimen is not available This test should not be used for newborn screening followup.