3A5Q - Overview: Cytochrome P450 3A5 Genotype, Varies

Aids in optimizing treatment with tacrolimus and other drugs metabolized by cytochrome P450 3A5

CATU - Overview: Catecholamine Fractionation, Free, 24 Hour, Urine

An auxiliary test to fractionated plasma and urine metanephrine measurements in the diagnosis of pheochromocytoma and paraganglioma An auxiliary test to urine vanillylmandelic acid and homovanillic acid determination in the diagnosis and...

I2SWB - Overview: Iduronate-2-Sulfatase, Leukocytes

Supporting the biochemical diagnosis of mucopolysaccharidosis II (MPS II; Hunter syndrome) in whole blood specimens This test is not useful for carrier detection for MPS II.

OPTMX - Overview: Opiate Confirmation, Chain of Custody, Meconium

Detecting maternal prenatal opiate/opioid use up to 5 months before birth Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the...

GSH - Overview: Glutathione, Blood

Evaluation of neonatal hyperbilirubinemia, favism or chronic or episodic hemolysis or jaundice Evaluation for gamma-glutamylcysteine synthetase deficiency Evaluation for glutathione synthetase deficiency causing hemolytic anemia...

FERR1 - Overview: Ferritin, Serum

Aiding in the diagnosis of iron deficiency and iron overload conditions Differentiating iron deficiency anemia and anemia of chronic disease

SM - Overview: Smith (Sm) Antibodies, IgG, Serum

Evaluating patients with clinical features suggestive of antinuclear antibody associated connective tissue disease and the confirmation of a diagnosis of systemic lupus erythematosus. Testing for Smith antibodies is not useful in patients...

TABSU - Overview: Targeted Benzodiazepine Screen, Random, Urine

Qualitatively (present vs not detected) identifying 27 benzodiazepine compounds (parent drug and metabolites) in urine to help determine compliance or identify illicit benzodiazepine drug use This test is not intended for...

TBSU - Overview: Targeted Benzodiazepine Screen, Random, Urine

Determining compliance or identifying illicit benzodiazepine drug use This test is not intended for employment-related testing.

HL58R - Overview: HLA-B*5801 Genotype, Allopurinol Hypersensitivity, Varies

Identifying individuals with an increased risk of severe cutaneous adverse reactions to allopurinol based on the presence of the human leukocyte antigen HLA-B*58:01 allele

FCYTP - Overview: Cytokine Panel 13, Serum

Cytokine Panel 13, Serum

FPNAP - Overview: Pneumococcal Antibody Panel (12 Serotype)

Pneumococcal Antibody Panel (12 Serotype)

NMOFS - Overview: Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay, Serum

Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD) Diagnosis of autoimmune AQP4 channelopathy Diagnosis of neuromyelitis optica (NMO) Distinguishing NMOSD from multiple sclerosis early in the course of disease

PD2T - Overview: Pompe Disease Second-Tier Newborn Screening, Blood Spot

Second-tier testing of newborns with an abnormal primary screening result for Pompe disease (decreased acid alpha-glucosidase enzyme activity) Follow-up testing for evaluation of an abnormal newborn screening result for Pompe disease

SCAP - Overview: Spinocerebellar Ataxia Repeat Expansion Panel, Varies

Molecular confirmation of clinically suspected spinocerebellar ataxia when a specific subtype isn't suspected

FRBP - Overview: Retinol Binding Protein

Retinol Binding Protein

HBEL1 - Overview: Hemoglobin Electrophoresis Evaluation, Blood

Diagnosis and classification of hemoglobin disorders, including thalassemias and hemoglobin variants

SUP24 - Overview: Supersaturation Profile, 24 Hour, Urine

Diagnosis and management of patients with renal lithiasis: -Predicting the likely composition of the stone, in patients who have a radiopaque stone, for whom stone analysis is not available -May aid in designing a treatment program...

SSH24 - Overview: Supersaturation Profile, Self-Collect, 24 Hour, Urine

Diagnosis and management of patients with renal lithiasis: -Predicting the likely composition of the stone, in patients who have a radiopaque stone, for whom stone analysis is not available -May aid in designing a treatment program Aiding...

B2MU - Overview: Beta-2 Microglobulin, Random, Urine

Evaluation of renal tubular damage Monitoring exposure to cadmium and mercury

MSUSC - Overview: Branched-Chain Amino Acids, Self-Collect, Blood Spot

Monitoring patients with maple syrup urine disease using specimens collected at home

AK1 - Overview: Adenylate Kinase Enzyme Activity, Blood

Evaluation of chronic nonspherocytic hemolytic anemia

CRCRU - Overview: Chromium/Creatinine Ratio, Random, Urine

Detecting chromium exposure

HGU - Overview: Mercury, 24 Hour, Urine

Detecting mercury toxicity using 24-hour urine specimens

NIUC - Overview: Nickel/Creatinine Ratio, Random, Urine

Measurement of nickel concentration for biomonitoring nickel exposure

MOLPS - Overview: Molybdenum, Serum

Monitoring of parenteral nutrition Monitoring metallic prosthetic implant wear As an indicator of molybdenum cofactor deficiency

KRT5 - Overview: Keratin 5 (KRT5) Immunostain, Technical Component Only

Differentiation of mesothelioma and squamous cell carcinoma versus adenocarcinoma

MYOD1 - Overview: Myogenic Differentiation Antigen 1 (MYOD1) Immunostain, Technical Component Only

Marker of skeletal muscle differentiation

SPNEU - Overview: Streptococcus pneumoniae Antigen, Random, Urine

Rapid diagnosis of pneumococcal pneumonia

ZONI - Overview: Zonisamide, Serum

Monitoring zonisamide therapy; recommended for all patients to ensure appropriate dosing Assessing medication compliance

AMLPF - Overview: Acute Myeloid Leukemia (AML), FISH, Pediatric, Varies

This test should not be used to screen for residual acute myeloid leukemia (AML). Useful at diagnosis for detecting recurrent common chromosome abnormalities in pediatric patients with AML An adjunct to chromosome studies in patients with...

MMRV - Overview: Measles, Mumps, Rubella, and Varicella (MMRV) Immune Status Profile, Serum

Determining immune status of individuals to measles, mumps, rubella, and varicella-zoster viruses (VZV) Documentation of previous infection with measles, mumps, rubella, or VZV in an individual without a previous record of immunization to...

CVHBG - Overview: Comprehensive Cerebrovascular Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of a monogenic condition in which there is an increased risk for a cerebrovascular accident Establishing a diagnosis of a monogenic condition in which...

FIXCF - Overview: Immunofixation, CSF

Immunofixation, CSF

FFTFT - Overview: Testosterone, Free (Dialysis) and Total, MS

Helpful in assessing testicular function in prepubescent hypogonadal males and in managing hirsutism and virilization in females

GAAW - Overview: Acid Alpha-Glucosidase, Leukocytes

Diagnosis of Pompe disease

CARU - Overview: Cyclic Adenosine Monophosphate (cAMP), Urinary Excretion, Serum and Urine

Differential diagnosis of hypercalcemia As an adjunct to serum parathyroid hormone measurements, especially in the diagnosis of parathyroid hormone resistance states, such as pseudohypoparathyroidism

PRA - Overview: Renin Activity, Plasma

Investigation of primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter...

LKM - Overview: Liver/Kidney Microsome Type 1 Antibodies, Serum

Evaluation of patients with liver disease of unknown etiology Evaluation of patients with suspected autoimmune hepatitis

T4 - Overview: T4 (Thyroxine), Total Only, Serum

Monitoring treatment with synthetic hormones (synthetic T3 [triiodothyronine] will cause a low total T4 [thyroxine]) Monitoring treatment of hyperthyroidism with thiouracil and other anti-thyroid drugs Index of thyroid function when the...

BNZU - Overview: Benzodiazepines Confirmation, Random, Urine

Detecting drug use involving benzodiazepines such as alprazolam, chlordiazepoxide, clonazepam, diazepam, midazolam, oxazepam, temazepam, clobazam, flunitrazepam, flurazepam, lorazepam, prazepam, triazolam, and zolpidem

AACSF - Overview: Amino Acids, Quantitative, Spinal Fluid

Evaluating patients with possible inborn errors of amino acid metabolism, particularly nonketotic hyperglycinemia (glycine encephalopathy) and serine biosynthesis defects, especially when used in conjunction with concomitantly collected...

H2MT - Overview: HER2 Amplification, Miscellaneous Tumor, FISH, Tissue

Guiding cancer therapy, as patients with HER2 amplification may be candidates for therapies that target the human epidermal growth factor receptor 2 (HER2) protein (eg, trastuzumab [Herceptin], pertuzumab) Confirming the presence of HER2...

OXYBS - Overview: Oxysterols, Blood Spot

Investigating a possible diagnosis of Niemann-Pick disease types A, B, or C using blood spot specimens Monitoring of individuals with Niemann-Pick disease type C This test is not useful for the identification of carriers.

MCLIP - Overview: Phospholipid (Cardiolipin) Antibodies, IgM, Serum

The following clinical situations, when used in conjunction with other criterial antiphospholipid antibody tests: -Unexplained arterial or venous thrombosis -A history of pregnancy morbidity defined as 1 or more unexplained deaths of a...

EFPO - Overview: Electrolyte and Osmolality Panel, Feces

Workup of cases of chronic diarrhea Diagnosis of factitious diarrhea (where patient adds water to stool to simulate diarrhea)

MPS4B - Overview: Mucopolysaccharidosis IV Enzyme Panel, Blood Spot

Supporting the biochemical diagnosis of mucopolysaccharidosis type IVA and IVB This test is not useful for carrier detection.

PNTO - Overview: Streptococcus pneumoniae IgG Antibodies, Total, Serum

Assessing the IgG antibody response to active immunization with nonconjugated 23-valent pneumococcal vaccines Assessing the IgG antibody response to active immunization with conjugated 13-valent, 15-valent and 20-valent pneumococcal...

ACRN - Overview: Acylcarnitines, Quantitative, Plasma

Diagnosis of fatty acid oxidation disorders and several organic acidurias using plasma specimens Evaluating treatment during follow-up of patients with fatty acid beta-oxidation disorders and several organic acidurias

JIP - Overview: Joint Infection Panel, PCR, Synovial Fluid

Rapid detection of synovial fluid infections caused by the following: Anaerococcus prevotii/vaginalis Finegoldia magna Streptococcus species Clostridium perfringens Parvimonas micra Streptococcus agalactiae Cutibacterium...