GCLIP - Overview: Phospholipid (Cardiolipin) Antibodies, IgG, Serum

The following clinical situations, when used in conjunction with other criterial antiphospholipid antibody tests: -Unexplained arterial or venous thrombosis -A history of pregnancy morbidity defined as 1 or more unexplained deaths of a...

SERWB - Overview: Serotonin, Blood

In conjunction with, or as an alternative to, first-order tests in the differential diagnosis of isolated symptoms suggestive of carcinoid syndrome, in particular flushing (5-hydroxyindoleacetic acid or serum chromogranin A measurements are...

RAVMP - Overview: Ravulizumab Monitoring Panel, Serum

Monitoring of complement blockage by ravulizumab Assessing the response to ravulizumab therapy Assessing the need for dose escalation Evaluating the potential for dose deescalation or discontinuation of therapy in remission...

PBC2 - Overview: SP100 and GP210 Antibodies, IgG, Serum

Evaluating the risk of primary biliary cholangitis in anti-mitochondrial antibody (AMA)-negative patients by identification of Sp100 and gp210 antibodies Estimating risk in AMA-positive patients with incomplete feature of disease

MCMRU - Overview: Mast Cell Mediators, Random, Urine

Evaluating patients at risk for mast cell activation syndrome (eg, systemic mastocytosis) using random urine collections

AHUGP - Overview: Atypical Hemolytic Uremic Syndrome (aHUS)/Thrombotic Microangiopathy (TMA) /Complement 3 Glomerulopathy (C3G) Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of atypical hemolytic uremic syndrome (aHUS), thrombotic microangiopathy (TMA), or complement 3 glomerulopathy (C3G) Establishing a diagnosis of...

GNF7 - Overview: Factor VII Deficiency, F7 Gene, Next-Generation Sequencing, Varies

Evaluating factor VII deficiency (FVIID) in patients with a personal or family history suggestive of FVIID Confirming an FVIID diagnosis with the identification of known or suspected disease-causing alterations in the F7 gene...

F_9 - Overview: Coagulation Factor IX Activity Assay, Plasma

Diagnosing deficiencies, particularly hemophilia B (Christmas disease) Assessing the impact of liver disease on hemostasis Investigation of a prolonged activated partial thromboplastin time

ETGS - Overview: Ethyl Glucuronide Screen, Random, Urine

Screening for drug abuse involving alcohol

DIG - Overview: Digoxin, Serum

Monitoring digoxin therapy

CURCU - Overview: Copper/Creatinine Ratio, Random, Urine

Investigation of Wilson disease and obstructive liver disease using a random urine specimen

F_7 - Overview: Coagulation Factor VII Activity Assay, Plasma

Diagnosing congenital deficiency of coagulation factor VII Evaluating acquired deficiencies associated with liver disease, oral anticoagulant therapy, and vitamin K deficiency Determining degree of anticoagulation with warfarin to...

HEPTP - Overview: Heparin Anti-Xa, Plasma

Measuring heparin concentration: -In patients treated with low-molecular-weight heparin preparations -In the presence of prolonged baseline activated partial thromboplastin time (APTT) (eg, lupus anticoagulant, "contact factor" deficiency,...

IGGS4 - Overview: IgG4, Immunoglobulin Subclasses, Serum

Supporting the diagnosis of IgG4-related disease

GATOL - Overview: Galactitol, Quantitative, Urine

Monitoring effectiveness of treatment in patients with galactosemia Establishing a baseline level prior to initiating treatment for galactosemia

CLFIB - Overview: Fibrinogen, Clauss, Plasma

Detecting increased or decreased fibrinogen (factor 1) concentration of acquired or congenital origin Monitoring severity and treatment of disseminated intravascular coagulation and fibrinolysis

MUM1B - Overview: MUM-1/IRF4 Immunostain, Bone Marrow, Technical Component Only

Aiding in the identification of hematolymphoid neoplasms and melanomas

NITU - Overview: Nitrogen, Total, 24 Hour, Urine

Assessing nutritional status (protein malnutrition) Assessment of protein nutrition and nitrogen balance in hospitalized patients Evaluating protein catabolism Determining nitrogen balance, when used in conjunction with 24-hour fecal...

SP142 - Overview: Programmed Death-Ligand 1 (PD-L1) (SP142), Semi-Quantitative Immunohistochemistry, Manual

Identification of neoplasms expressing programmed cell death 1-ligand 1 (clone SP142)

22C3 - Overview: Programmed Death-Ligand 1 (PD-L1) (22C3), Semi-Quantitative Immunohistochemistry, Manual

Identification of neoplasms expressing programmed cell death 1-ligand 1 (clone 22C3)

PFK1 - Overview: Phosphofructokinase Enzyme Activity, Blood

Evaluation of individuals with Coombs-negative nonspherocytic hemolytic anemia Evaluation of individuals with exercise intolerance or myopathy Genetic studies in families with phosphofructokinase deficiency

PFKC - Overview: Phosphofructokinase Enzyme Activity, Blood

Evaluation of individuals with Coombs-negative nonspherocytic hemolytic anemia Evaluation of individuals with exercise intolerance or myopathy Genetic studies in families with phosphofructokinase deficiency

SP263 - Overview: Programmed Death-Ligand 1 (PD-L1) (SP263), Semi-Quantitative Immunohistochemistry, Manual

Identification of neoplasms expressing programmed cell death 1-ligand 1 (clone SP263)

TGII - Overview: Thyroglobulin, Interference Interpretation

Interpretation for the evaluation of suspected interference from heterophile antibodies causing a falsely elevated thyroglobulin result

TLU - Overview: Thallium, 24 Hour, Urine

Detecting toxic thallium exposure in 24-hour urine collections

CYTH1 - Overview: T-Helper Cell Type 1 Cytokine Panel, Plasma

Assessment of plasma cytokine levels to understand the etiology of autoimmune and proinflammatory conditions when used in conjunction with clinical information and other laboratory testing

SCERG - Overview: Saccharomyces cerevisiae Antibody, IgG, Serum

Measuring IgG anti-Saccharomyces cerevisiae antibodies as a part of a profile to aid in distinguishing between ulcerative colitis and Crohn disease in patients for whom the specific diagnosis is unclear based on endoscopic, pathologic, and...

TICU - Overview: Titanium/Creatinine Ratio, Urine

Measurement of titanium concentration as part of a profile to assess exposure and elimination of titanium

CMET - Overview: cMET Immunostain, Technical Component Only

Identification of normal and neoplastic c-Met expressing cells

ZNCU - Overview: Zinc/Creatinine Ratio, Urine

Measurement of zinc concentration as a part of identifying the cause of abnormal serum zinc concentrations using a random urine specimen

ZNUCR - Overview: Zinc/Creatinine Ratio, Random, Urine

Identifying the cause of abnormal serum zinc concentrations using a random urine specimen

VLTS - Overview: Volatile Screen, Serum

Detection and quantitation of acetone, methanol, isopropanol, and ethanol in serum Quantification of the concentration of ethanol in serum correlates with degree of intoxication Evaluation of toxicity to the measured volatile substances

CALCI - Overview: Calcitonin (CALCI) Immunostain, Technical Component Only

Aids in the identification of C cells of thyroid, medullary thyroid carcinomas, many atypical laryngeal carcinoids, and other neuroendocrine tumors

LACTO - Overview: Lactotransferrin Immunostain, Technical Component Only

Identifying the presence of lactotransferrin in amyloid deposits An adjunct to amyloid-subtyping analysis by mass spectrometry

MUM1 - Overview: MUM-1/IRF4 Immunostain, Technical Component Only

Aids in the identification of hematolymphoid neoplasms and melanomas

P40 - Overview: p40 Immunostain, Technical Component Only

Diagnosis and classification of carcinomas and lymphomas

SV40 - Overview: SV40 Immunostain, Technical Component Only

Identifying BK or JC polyomavirus

PFAPE - Overview: Fatty Acid Profile, Essential, Plasma

Evaluating the nutritional intake and intestinal absorption of essential fatty acids using plasma specimens Identifying deficiency of essential and other nutritionally beneficial fatty acids Monitoring treatment of patients with essential...

BHCG - Overview: Beta-Human Chorionic Gonadotropin, Quantitative, Serum

Monitoring patients for retained products of conception Aiding in the diagnosis of gestational trophoblastic disease (GTD), testicular tumors, ovarian germ cell tumors, teratomas, and, rarely, other human chorionic gonadotropin...

B2GMG - Overview: Beta-2 Glycoprotein 1 Antibodies, IgG and IgM, Serum

Evaluating patients with suspected antiphospholipid syndrome by identification of beta-2 glycoprotein 1 IgM and IgG antibodies First-line test when antiphospholipid syndrome is strongly suspected in conjunction with cardiolipin antibodies...

FAPEP - Overview: Fatty Acid Profile, Essential, Serum

Evaluating the nutritional intake and intestinal absorption of essential fatty acids using serum specimens Identifying deficiency of essential and other nutritionally beneficial fatty acids Monitoring treatment of patients with essential...

G6PDC - Overview: Glucose 6 Phosphate Dehydrogenase Enzyme Activity, Blood

Evaluation of individuals with episodic or chronic Coombs-negative nonspherocytic hemolytic anemia Rapid testing to assess glucose-6-phosphate dehydrogenase (G6PD) enzyme capacity prior to rasburicase or other therapies that may cause...

GCT - Overview: Galactosemia Reflex, Blood

Preferred test for diagnosis, carrier detection, and determination of genotype of galactose-1-phosphate uridyltransferase deficiency, the most common cause of galactosemia Differentiating Duarte variant galactosemia from classic...

META3 - Overview: Metanephrines with 3-Methoxytyramine, 24 Hour, Urine

A first- and second-tier screening test for the presumptive diagnosis of catecholamine-secreting pheochromocytomas and paragangliomas

CLPMG - Overview: Phospholipid (Cardiolipin) Antibodies, IgG and IgM, Serum

The following clinical situations: -Unexplained arterial or venous thrombosis -A history of pregnancy morbidity defined as 1 or more unexplained deaths of a morphologically normal fetus beyond the 10th week of gestation, 1 or more premature...

SYPH1 - Overview: Syphilis IgG with Reflex, Enzyme Immunoassay, Serum

Aid for the diagnosis of infection with Treponema pallidum using an algorithmic approach Routine prenatal screening This test is not offered as a screening or confirmatory test for blood donor specimens. This test is not useful for...

SERU - Overview: Serotonin, 24 Hour, Urine

Diagnosis of a small subgroup of carcinoid tumors that produce predominately 5-hydroxytryptophan (5-HTP) but very little serotonin and chromogranin A Follow-up for patients with known or treated carcinoid tumors that produce predominately...

DPYDQ - Overview: Dihydropyrimidine Dehydrogenase Genotype, Varies

Identifying individuals with genetic variants in DPYD who are at increased risk of toxicity when prescribed 5-fluorouracil (5-FU) or capecitabine chemotherapy treatment

NMS1 - Overview: Necrotizing Myopathy Evaluation, Serum

Evaluating patients with suspected necrotizing autoimmune myopathy

MCM24 - Overview: Mast Cell Mediators, 24 Hour, Urine

Evaluating patients at risk for mast cell activation syndrome (eg, systemic mastocytosis) using 24-hour urine collections