LMO2 - Overview: LIM Domain Only 2 (LMO2) Immunostain, Technical Component Only
Classification of lymphomas
C5B9 - Overview: SC5b-9 Level Terminal Complement Complex, Plasma
Detecting increased complement activation
TCGBM - Overview: T-Cell Receptor Gene Rearrangement, PCR, Bone Marrow
Determining whether a T-cell population is polyclonal or monoclonal
TCGR - Overview: T-Cell Receptor Gene Rearrangement, PCR, Blood
Determining whether a T-cell population is polyclonal or monoclonal using blood specimens
LALB - Overview: Lysosomal Acid Lipase, Blood
Evaluation of patients with a clinical presentation suggestive of lysosomal acid lipase deficiency using blood specimens This test is not useful to determine carrier status for cholesteryl ester storage disease or Wolman disease.
Investigation of suspected folate deficiency
IFBA - Overview: Intrinsic Factor Blocking Antibody, Serum
Confirming the diagnosis of pernicious anemia
TCGRV - Overview: T-Cell Receptor Gene Rearrangement, PCR, Varies
Determining whether a T-cell population is polyclonal or monoclonal using body fluid or tissue specimens
C341Q - Overview: Complement C3 and C4 with Anti-C1q Antibodies, Serum
Evaluating patients with suspected anti-C1q vasculitis Predicting renal involvement in patients with systemic lupus erythematosus
BCGRV - Overview: Immunoglobulin Gene Rearrangement, PCR, Varies
Determining whether a B-cell or plasma cell population is polyclonal or monoclonal in specimens other than blood or bone marrow Identifying neoplastic cells as having B-cell or plasma cell differentiation Monitoring for a persistent...
LALBS - Overview: Lysosomal Acid Lipase, Blood Spot
Evaluation of patients with a clinical presentation suggestive of lysosomal acid lipase deficiency using blood spot specimens This test is not useful to determine carrier status for cholesteryl ester storage disease or Wolman disease.
Second-tier testing of newborns with an abnormal primary screening result for mucopolysaccharidosis type I (MPS I) (decreased alpha-L-iduronidase activity) Follow-up testing for evaluation of an abnormal newborn screening result for MPS...
LCAF - Overview: Lung Cancer, ALK (2p23) Rearrangement, FISH, Tissue
Identifying patients with non-small cell lung carcinoma who may benefit from treatment with directed tyrosine kinase inhibitors
F8INV - Overview: Hemophilia A F8 Gene, Intron 1 and 22 Inversion Mutation Analysis, Whole Blood
First-tier molecular testing for male patients affected with severe hemophilia A when a variant has not been identified in the family Determining hemophilia A carrier status for at-risk female patients, ie, individuals with a family...
Aiding in the diagnosis of new cases of multiple myeloma or other plasma cell proliferative disorders using a fixed cell pellet derived from bone marrow Identifying prognostic markers based on the abnormalities found This test should...
F822P - Overview: Hemophilia A F8 Gene, Intron 22 Inversion Mutation Analysis, Prenatal
Prenatal testing for hemophilia A when a F8 intron 22 inversion has been identified in a family member
F822B - Overview: Hemophilia A F8 Gene, Intron 22 Inversion Known Mutation, Whole Blood
First-tier molecular testing for male patients affected with severe hemophilia A, when a familial intron 22 inversion has been previously identified Determining hemophilia A carrier status for at-risk female patients, ie, individuals with...
Aiding in the diagnosis of new cases of multiple myeloma or other plasma cell proliferative disorders using bone marrow specimens Identifying prognostic markers based on the abnormalities found This test should not be used to track the...
MPCDS - Overview: mSMART, Plasma Cell Proliferative Disorder, FISH, Bone Marrow
Aiding in the diagnosis of new cases of multiple myeloma or other plasma cell proliferative disorders as a part of a profile Identifying prognostic markers based on the anomalies found
SQTSG - Overview: Short QT Syndrome Gene Panel, Varies
Providing a genetic evaluation for patients with a personal or family history suggestive of short QT syndrome Establishing a diagnosis of short QT syndrome
F8INP - Overview: Hemophilia A F8 Gene, Intron 1 and 22 Inversion Mutation Analysis, Prenatal
Prenatal testing for hemophilia A when a variant has not been identified in the family
MDYSP - Overview: Inherited Muscular Dystrophy Gene Panel, Varies
Establishing a molecular diagnosis for patients with muscular dystrophy Identifying variants within genes known to be associated with muscular dystrophy, allowing for predictive testing of at-risk family members
RETB - Overview: Reticulocyte Profile, Blood
Assessing erythropoietic bone marrow activity in anemia and other hematologic conditions Assessment of acute iron deficiency Monitoring early response to iron therapy or erythropoiesis-stimulating agents Early monitoring of therapy for...
CBC - Overview: Complete Blood Cell Count (CBC) with Differential, Blood
Screening tool to confirm a hematologic disorder, to establish or rule out a diagnosis, to detect an unsuspected hematologic disorder, or to monitor effects of radiation or chemotherapy
HCYSS - Overview: Homocysteine, Total, Serum
An aid for screening patients suspected of having an inherited disorder of methionine metabolism including: -Cystathionine beta-synthase deficiency (homocystinuria) -Methylenetetrahydrofolate reductase deficiency and its thermolabile...
HCYSP - Overview: Homocysteine, Total, Plasma
An aid for screening patients suspected of having an inherited disorder of methionine metabolism including: -Cystathionine beta-synthase deficiency (homocystinuria) -Methylenetetrahydrofolate reductase deficiency and its thermolabile...
HAEV1 - Overview: Hemolytic Anemia Evaluation, Blood
Evaluation of lifelong or inherited hemolytic anemias, including red blood cell membrane disorders, unstable or abnormal hemoglobin variants, and red blood cell enzyme disorders This evaluation is not suitable for acquired causes of...
CRDPP - Overview: Creatine Disorders Panel, Plasma
Evaluating patients with a clinical suspicion of arginine:glycine amidinotransferase deficiency, guanidinoacetate methyltransferase deficiency, and creatine transporter deficiency using plasma specimens
CRDPS - Overview: Creatine Disorders Panel, Serum
Evaluating patients with a clinical suspicion of arginine:glycine amidinotransferase deficiency,guanidinoacetate methyltransferase deficiency, and creatine transporter deficiency using serum specimens
AACSF - Overview: Amino Acids, Quantitative, Spinal Fluid
Evaluating patients with possible inborn errors of amino acid metabolism, particularly nonketotic hyperglycinemia (glycine encephalopathy) and serine biosynthesis defects, especially when used in conjunction with concomitantly collected...
LIVPR - Overview: Liver Profile, Serum
Screening for liver damage, especially if someone has a condition or is taking a drug that may affect the liver
FCLNE - Overview: Anti-Phosphatidylcholine Ab
Anti-Phosphatidylcholine Ab
FPHET - Overview: Anti-Phosphatidylethanolamine Panel
Anti-Phosphatidylethanolamine Panel
FCYTP - Overview: Cytokine Panel 13, Serum
Cytokine Panel 13, Serum
CLLDF - Overview: Chronic Lymphocytic Leukemia, Diagnostic FISH, Varies
Detecting recurrent common chromosome abnormalities in patients with chronic lymphocytic leukemia (CLL) Distinguishing patients with 11;14 translocations who have the leukemic phase of mantle cell lymphoma from patients who have...
LH - Overview: Luteinizing Hormone (LH), Serum
An adjunct in the evaluation of menstrual irregularities Evaluating patients with suspected hypogonadism Predicting ovulation Evaluating infertility Diagnosing pituitary disorders
LFRI - Overview: Progentec aiSLE DX Lupus Flare Risk Index, Plasma
Aiding in the assessment of risk of flare in lupus patients when used in conjunction with standard clinical assessment
PLHBB - Overview: Plasma Free Hemoglobin, Plasma
Determining whether hemolysis is occurring such as from: -Transfusion reaction -Mechanical fragmentation of red blood cells -Relative comparison to baseline levels in extracorporeal membrane oxygenation and centrifugal ventricular assist...
FFRFT - Overview: Anti-Synthetase Profile
Anti-Synthetase Profile
FSH - Overview: Follicle-Stimulating Hormone (FSH), Serum
An adjunct in the evaluation of menstrual irregularities Evaluating patients with suspected hypogonadism Predicting ovulation Evaluating infertility Diagnosing pituitary disorders
PGSN - Overview: Progesterone, Serum
Ascertaining whether ovulation occurred in a menstrual cycle Assessment of infertility Evaluation of abnormal uterine bleeding Evaluation of placental health in high-risk pregnancy Determining the effectiveness of progesterone...
CMMPS - Overview: Cobalamin, Methionine, and Methylmalonic Acid Pathways, Serum
Screening and monitoring patients suspected of or confirmed with an inherited disorder of methionine, cobalamin, or propionate metabolism using serum specimens Evaluating individuals with suspected deficiency of vitamin B12
CMMPP - Overview: Cobalamin, Methionine, and Methylmalonic Acid Pathways, Plasma
Screening and monitoring patients suspected of or confirmed with an inherited disorder of methionine, cobalamin, or propionate metabolism using plasma specimens Evaluating individuals with suspected deficiency of vitamin B12
URIC - Overview: Uric Acid, Serum
Diagnosis and treatment of renal failure Monitoring patients receiving cytotoxic drugs and a variety of other disorders, including gout, leukemia, psoriasis, starvation and other wasting conditions
GENRA - Overview: Gentamicin, Random, Serum
Monitoring adequacy of serum concentration during gentamicin therapy in specimens for which no collection timing information is provided
SFIG - Overview: Cerebrospinal Fluid IgG Index Profile, Serum and Spinal Fluid
Aiding in the diagnosis of multiple sclerosis and other central nervous system inflammatory conditions
FIGF1 - Overview: IGF-1, LC/MS
IGF-1, LC/MS
UBT - Overview: Helicobacter pylori Breath Test
Diagnostic testing for Helicobacter pylori infection in patients suspected to have active H pylori infection Monitoring response to therapy This test is not appropriate for asymptomatic people.
NPM1Q - Overview: Nucleophosmin (NPM1) Mutation Analysis, Varies
As a prognostic indicator in patients with newly diagnosed acute myelogenous leukemia with normal karyotype and no FLT3 variant and as a leukemia-specific marker of minimal residual disease
ACRNS - Overview: Acylcarnitines, Quantitative, Serum
Diagnosis of fatty acid oxidation disorders and several organic acidurias using serum specimens Evaluating treatment during follow-up of patients with fatty acid beta-oxidation disorders and several organic acidurias
Information: Interpreting Laboratory Tests to Determine New vs. Residual Use of Marijuana - Insights
In this month's "Hot Topic," Paul Jannetto, Ph.D., identifies how to determine new vs. residual use of marijuana in a patient, and teaches how to calculate the carboxy-tetrahydrocannabinol (carboxy-THC)...
Laboratory and Pathology Research Roundup: March 12 - Insights
known. We performed laser microdissection (LCM) of glomeruli followed by mass spectrometry (MS) in 12 cases each of DDD, C3GN, and pretransplant kidney control biopsies....
COVID-19: At-home sample collection vs. at-home testing - Insights
The concept of at-home testing for COVID-19 sounds straightforward. But there's nuance to it that's important to understand. Right now, an at-home test for COVID-19 is not available, although there may be one coming soon. But in some areas,...
Clinic Laboratory and Pathology Research Roundup: Nov. 12 - Insights
This week’s Research Roundup highlights a mechanism for preventing asymmetric histone segregation onto replicating DNA strands.
Transfusion Toons: A1 vs. A2 - Insights
Justin Kreuter, M.D., Clinical Pathologist and Medical Director of the Mayo Clinic Blood Donor Center in Rochester, Minnesota, and Theresa Malin, an Education Specialist in Transfusion Medicine at Mayo Clinic, have launched “Transfusion...