Detection and differentiation between recent, past/resolved, or chronic hepatitis B Diagnosis of recent hepatitis B virus (HBV) infection during the "window period" when both hepatitis B surface (HBs) antigen and anti-HBs are negative...
HCVL - Overview: Hepatitis C Virus Antibody Confirmation, Serum
Confirming the presence of hepatitis C virus (HCV)-specific IgG antibodies in serum specimens that are reactive by HCV antibody screening tests Distinguishing between true- and false-reactive HCV antibody screening test results This test...
NAIFA - Overview: Antinuclear Antibodies, HEp-2 Substrate, IgG, Serum
Evaluation of patients suspected of having systemic autoimmune rheumatic disease (ANA-associated rheumatic diseases or connective tissue disease) or organ-specific autoimmune diseases such as autoimmune liver diseases
Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD) Diagnosis of autoimmune AQP4 channelopathy Distinguishing NMOSD from multiple sclerosis early in the course of disease
TPPA - Overview: Syphilis Antibody, Treponema pallidum Particle Agglutination, Serum
An aid to resolve discrepant results between screening treponemal and non-treponemal assays This test is not recommended for general screening purposes for syphilis. This test should not be used to evaluate response to therapy. This test...
CTBID - Overview: Culture Referred for Identification, Mycobacterium and Nocardia, Varies
Rapid identification to the species level for Mycobacterium species, Nocardia species, and other aerobic actinomycete genera and species from pure culture isolates
DPYDZ - Overview: Dihydropyrimidine Dehydrogenase, DPYD Full Gene Sequencing, Varies
Identifying individuals at increased risk of toxicity when considering 5-fluorouracil and capecitabine chemotherapy treatment Identifying common and rare variants associated with decreased or absent dihydropyrimidine dehydrogenase (DPD)...
EBVAB - Overview: Epstein-Barr Virus Antibody Profile, Serum
Diagnosis of Epstein-Barr virus (EBV) infectious mononucleosis or other EBV related infections Identification of prior EBV infection as part of pre-immunosuppression screening This assay is not intended for viral isolation or...
WESDX - Overview: Whole Exome Sequencing for Hereditary Disorders, Varies
Serving as a first-tier test to identify a molecular diagnosis in patients with suspected genetic disorders, which can allow for: -Better understanding of the natural history/prognosis -Targeted management (anticipatory guidance, management...
FPEPI - Overview: Pepsinogen I (PG I)
Pepsinogen I (PG I)
FWARP - Overview: Warfarin, Plasma
Warfarin, Plasma
FOVAS - Overview: Ovarian Antibody Screen with Reflex to Titer, IFA
Ovarian Antibody Screen with Reflex to Titer, IFA
FCARO - Overview: Carotene, Beta
Confirm the diagnosis of carotenoderma; detect fat malabsorption; depressed carotene levels may be found in cases of steatorrhea.
FMETN - Overview: Metformin, Plasma
Metformin, Plasma
PSYCF - Overview: Psychosine, Spinal Fluid
Aiding in the biochemical diagnosis of Krabbe disease using cerebrospinal fluid specimens Follow-up of individuals affected with Krabbe disease Follow-up testing after an abnormal newborn screening result for Krabbe disease Monitoring...
TRYPT - Overview: Tryptase, Serum
Evaluation of individuals with suspected mast cell activation, which may occur as a result of anaphylaxis or allergen challenge Evaluation of patients with suspected mast cell activation syndrome Evaluation of patients with suspected...
T4 - Overview: T4 (Thyroxine), Total Only, Serum
Monitoring treatment with synthetic hormones (synthetic T3 [triiodothyronine] will cause a low total T4 [thyroxine]) Monitoring treatment of hyperthyroidism with thiouracil and other anti-thyroid drugs Index of thyroid function when the...
DCORT - Overview: 11-Deoxycortisol, Serum
Diagnostic workup of patients with congenital adrenal hyperplasia Part of metyrapone testing in the workup of suspected secondary or tertiary adrenal insufficiency Part of metyrapone testing in the differential diagnostic workup of...
HMGCR - Overview: 3-Hydroxy-3-Methylglutaryl Coenzyme-A (HMG-CoA) Reductase, Serum
Evaluating patients with suspected necrotizing autoimmune myopathy Measuring 3-hydroxy-3-methylglutaryl-CoA reductase antibodies
ROMA - Overview: ROMA Score (Ovarian Malignancy Risk Algorithm), Serum
Risk assessment for finding an ovarian malignancy during surgery in women who present with an adnexal mass The test is not intended as a screening or stand-alone diagnostic assay for ovarian cancer.
T4BPE - Overview: Thyroxine-Binding Protein Electrophoresis, Serum
Explaining unusual thyroxine (T4), free T4, and thyroxine-binding globulin test results that do not correlate with the patient's clinical presentation Detecting the presence of aberrant thyroxine-binding proteins, such as abnormal forms...
HOLDC - Overview: Hematologic Disorders, Chromosome Hold, Varies
Holding the bone marrow or peripheral blood specimen in the laboratory but delaying chromosome analysis while preliminary morphologic assessment is in process
Screening for colonization of extended-spectrum beta-lactamase (ESBL)-producing organisms in stool Screening fecal microbiota transplant donor feces for ESBL-producing organisms. This test is not intended for medicolegal use.
FLCS - Overview: Immunoglobulin Free Light Chains, Serum
Monitoring serum from patients with monoclonal light chain diseases without a M-spike on protein electrophoresis May be useful as a diagnostic test in patients in whom there is a suspicion of primary systemic amyloidosis, light chain...
BRAFD - Overview: BRAF V600E/V600K Somatic Mutation Analysis, Tumor
Therapy selection for patients with cancer (eg, melanomas that may respond to BRAF inhibitors, colon cancers that may not respond to EGFR inhibitors) Aiding in the diagnosis/prognosis of certain cancers (eg, hairy cell leukemia, papillary...
Confirming the presence or absence of minimal residual disease in patients with known chronic lymphocytic leukemia who are either post-chemo/immunotherapy or post-bone marrow transplant
CMVP - Overview: Cytomegalovirus (CMV) Antibodies, IgM and IgG, Serum
Aiding in the diagnosis of acute or past infection with cytomegalovirus (CMV) Determining prior exposure to CMV This test should not be used for screening blood or plasma donors.
PREGN - Overview: Pregnenolone, Serum
An ancillary test for congenital adrenal hyperplasia, particularly in situations in which a diagnosis of both 21- and 11-hydroxylase deficiency have been ruled out Confirming a diagnosis of 3-beta-hydroxy dehydrogenase deficiency
RNAP - Overview: RNA Polymerase III Antibodies, IgG, Serum
Evaluating patients suspected of having systemic sclerosis as part of systemic sclerosis criteria antibody tests Providing diagnostic and prognostic information in patients with systemic sclerosis
CDPCR - Overview: Clostridioides difficile Toxin, PCR, Feces
Sensitive, specific, and rapid diagnosis of Clostridioides (Clostridium) difficile-associated diarrhea and pseudomembranous colitis The test is not recommended as a test of cure.
PINP - Overview: Procollagen I Intact N-Terminal, Serum
Aiding in monitoring antiresorptive and anabolic therapy in patients with osteoporosis An adjunct in the assessment of conditions associated with increased bone turnover, such as Paget disease This test should not be used as a screening...
PNP - Overview: Platelet Neutralization Procedure, Plasma
Aiding in the confirmation or exclusion of the presence of a lupus anticoagulant (LAC) inhibitor when used in conjunction with other appropriate coagulation tests. Aids in differentiating deficiencies or inhibitors of specific coagulation...
PAX2 - Overview: PAX2 Immunostain, Technical Component Only
Aiding in the diagnosis of endocervical adenocarcinoma and renal cell carcinoma
WNGC - Overview: West Nile Virus Antibody, IgG, Spinal Fluid
Aids in diagnosing recent or past central nervous system West Nile virus infection
VIM - Overview: Vimentin Immunostain, Technical Component Only
Identification of cells of mesenchymal origin in normal and neoplastic tissues
IDH1 - Overview: IDH1 Mutation (R132H) Immunostain, Technical Component Only
Classification of gliomas
IL5P - Overview: Interleukin 5, Plasma
Evaluation of patients with disorders known to be associated with hypereosinophilia
EM - Overview: Electron Microscopy, Varies
Providing information to aid in the diagnosis of medical disorders such as storage diseases, CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy), and primary ciliary dyskinesia
ORTHP - Overview: Orthostatic Proteinuria, Random, Urine
Diagnosis of orthostatic proteinuria
PARVI - Overview: Parvovirus Immunostain, Technical Component Only
Identification of parvovirus infection
PTH - Overview: Parathyroid Hormone (PTH) Immunostain, Technical Component Only
Identification of parathyroid glands
P40 - Overview: p40 Immunostain, Technical Component Only
Diagnosis and classification of carcinomas and lymphomas
P16 - Overview: p16 (INK4a/CDKN2A) Immunostain, Technical Component Only
Aids in the identification of human papilloma virus infection
RSVAB - Overview: Respiratory Syncytial Virus (RSV) In Situ Hybridization, Technical Component Only
Aids in the identification of respiratory syncytial viral infection
CD103 - Overview: CD103 Immunostain, Technical Component Only
Aids in the diagnosis of hairy cell leukemia and marginal zone lymphomas
CTSK - Overview: Cathepsin K Immunostain, Technical Component Only
Evaluation for perivascular epithelioid cell neoplasms (PEComas), alveolar soft part sarcoma, and translocation-associated renal cell carcinomas
TBET - Overview: T-Box Expressed in T Cells (TBET) Immunostain, Technical Component Only
Classification of lymphomas
HPYL - Overview: Helicobacter pylori (H pylori) Immunostain, Technical Component Only
Aiding in the identification of Helicobacter pylori infection
HAD - Overview: Huntington Disease, Molecular Analysis, Varies
Molecular confirmation of clinically suspected cases of Huntington disease (HD) Presymptomatic testing for individuals with a family history of HD and a documented expansion in the HTT gene
HMB45 - Overview: HMB45 Immunostain, Technical Component Only
Identification of activated and neoplastic melanocytes
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....
Week in Review: November 1 - Insights
Top highlights include: Facebook launches into the digital space of healthcare, medical breakthrough for Ebola, and how the brain makes memories.