HOLDC - Overview: Hematologic Disorders, Chromosome Hold, Varies
Holding the bone marrow or peripheral blood specimen in the laboratory but delaying chromosome analysis while preliminary morphologic assessment is in process
PBALP - Overview: Porphobilinogen and Aminolevulinic Acid, Plasma
An equivalent option to urine for first-line test for evaluation of a suspected acute porphyria Monitoring patients undergoing treatment for an acute intermittent porphyria or other acute porphyria
PMLR - Overview: PML::RARA Quantitative, PCR, Varies
Diagnosis of acute promyelocytic leukemia (APL) Detection of residual or recurrent APL Monitoring the level of PML::RARA (promyelocytic leukemia/retinoic acid receptor alpha) in APL patients
USTEK - Overview: Ustekinumab Quantitation with Antibodies, Serum
Evaluation of loss of response to therapy Quantification of ustekinumab in human serum Trough level quantitation for evaluation of patients treated with ustekinumab Detection of antibodies to ustekinumab in human serum
CALR - Overview: CALR Mutation Analysis, Myeloproliferative Neoplasm (MPN), Varies
Rapid and sensitive detection of insertion and deletion-type mutations in exon 9 of CALR Aiding in distinguishing between reactive thrombocytosis and leukocytosis versus a myeloproliferative neoplasm (MPN), especially essential...
NGHIS - Overview: MayoComplete Histiocytic Neoplasms, Next-Generation Sequencing, Varies
Aiding in establishing diagnosis, refining prognosis, and potentially identifying targeted therapies for the optimal management of patients with histiocytic neoplasms
FGHSP - Overview: Gamma-Hydroxybutyric Acid (GHB), Serum/Plasma
Gamma-Hydroxybutyric Acid (GHB), Serum/Plasma
FKEMS - Overview: Ketamine and Metabolite Screen, Plasma
Ketamine and Metabolite Screen, Plasma
FMMM - Overview: Mephedrone, MDPV and Methylone, Urine
Mephedrone, MDPV and Methylone, Urine
ALKLC - Overview: Anaplastic Lymphoma Kinase for Lung Cancer, Immunohistochemistry
Identification of anaplastic lymphoma kinase overexpression Diagnosis of inflammatory myofibroblastic tumor, anaplastic large-cell lymphoma, and for targeted therapy of lung adenocarcinoma
KIBM - Overview: Ki-67(MIB-1), Breast, Semi-Quantitative Immunohistochemistry, Manual
Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with breast carcinoma
GNBLC - Overview: Bleeding Disorders, Comprehensive Gene Panel, Next-Generation Sequencing, Varies
Evaluating hereditary bleeding in patients with a personal or family history suggestive of a hereditary bleeding disorder Confirming a hereditary bleeding disorder diagnosis with the identification of a known or suspected disease-causing...
NHEM - Overview: Hereditary Erythrocytosis Focused Gene Panel, Next-Generation Sequencing, Varies
Focused evaluation of an individual with JAK2-V617F negative erythrocytosis associated with lifelong sustained increased red blood cell (RBC) mass, hemoglobin, or hematocrit Providing a focused genetic evaluation for patients with a...
THEV1 - Overview: Thalassemia and Hemoglobinopathy Evaluation, Blood and Serum
Evaluation of microcytosis Extensive and economical diagnosis and classification of hemoglobinopathies or thalassemia, including complex disorders Diagnosis of hereditary persistence of hemoglobin
Follow-up testing to identify variants in individuals with a clinical diagnosis of cystic fibrosis (CF) Identifying genetic variants in individuals with atypical presentations of CF (eg, congenital bilateral absence of the vas deferens or...
CLADP - Overview: Congenital Lactic Acidosis Panel, Varies
Follow up for abnormal biochemical results suggestive of congenital lactic acidosis Establishing a molecular diagnosis for patients with congenital lactic acidosis Identifying variants within genes known to be associated with congenital...
Detecting a neoplastic clone associated with Philadelphia chromosome-like acute lymphoblastic leukemia (ALL), particularly when a classic abnormality is not detected with the initial panel An adjunct to conventional chromosome studies in...
NMEM - Overview: Red Blood Cell Membrane Disorders Gene Panel, Next-Generation Sequencing, Varies
Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of a red blood cell (RBC) membrane disorder Second-tier testing for patients in whom previous targeted gene variant analyses were...
HCVQG - Overview: Hepatitis C Virus (HCV) RNA Quantification with Reflex to HCV Genotype, Serum
Detection of acute hepatitis C virus (HCV) infection before the appearance of HCV antibodies in serum (ie, <2 months from exposure) Detection and confirmation of chronic HCV infection and determining HCV genotype (1 to 5) to guide...
MSP3 - Overview: Multiple Sclerosis (MS) Cascade, Serum and Spinal Fluid
Diagnosing multiple sclerosis, especially helpful in patients with equivocal clinical or radiological findings
MPSER - Overview: Mucopolysaccharides Quantitative, Serum
Quantification of dermatan sulfate, heparan sulfate, and keratan sulfate in serum to support the biochemical diagnosis of mucopolysaccharidoses types I, II, III, IV, VI, or VII
CELI - Overview: Celiac Associated HLA-DQ Alpha 1 and DQ Beta 1 DNA Typing, Blood
Assessing risk of celiac disease
F8INV - Overview: Hemophilia A F8 Gene, Intron 1 and 22 Inversion Mutation Analysis, Whole Blood
First-tier molecular testing for male patients affected with severe hemophilia A when a variant has not been identified in the family Determining hemophilia A carrier status for at-risk female patients, ie, individuals with a family...
F81B - Overview: Hemophilia A F8 Gene, Intron 1 Inversion Known Mutation, Whole Blood
First-tier molecular testing for male patients affected with severe hemophilia A, when a familial intron 1 inversion has been previously identified Determining hemophilia A carrier status for at-risk female patients, ie, individuals with...
CHF8 - Overview: Chromogenic Factor VIII Activity Assay, Plasma
Monitoring coagulation factor replacement therapy of selected extended half-life coagulation factor replacements Aiding in the diagnosis of hemophilia A using a 2-stage assay, especially when the 1-stage assay result was normal
MGMT - Overview: MGMT Promoter Methylation, Tumor
Prognostication of newly diagnosed patients with glioblastoma, IDH-wildtype Identifying newly diagnosed glioblastoma, IDH-wildtype patients that may respond to alkylating chemotherapy (ie, temozolomide) Guiding therapy decision making for...
PUPYP - Overview: Purines and Pyrimidines Panel, Plasma
Evaluating patients with symptoms suspicious for disorders of purine and pyrimidine metabolism Monitoring patients with disorders of purine and pyrimidine metabolism Laboratory evaluation of primary and secondary hyperuricemias Assessing...
BAP1 - Overview: BAP1 Immunostain, Technical Component Only
As part of a panel of immunostains where loss of staining can be used as a marker of various neoplasms
BUPR - Overview: Buprenorphine Screen with Reflex, Random, Urine
Screening and confirmation for drug abuse or use of buprenorphine
ETGR - Overview: Ethyl Glucuronide Screen with Reflex, Random, Urine
Screening and confirmation for drug abuse involving alcohol
HG34W - Overview: Histone 3.3 G34W (H3F3A G34W) Immunostain, Technical Component Only
Aiding in the diagnosis of giant cell tumor of bone
MUCN6 - Overview: Mucin 6, Immunostain, Technical Component Only
Aiding in subtyping intraductal papillary mucinous neoplasms as part of an immunopanel
MUCN5 - Overview: Mucin 5AC, Immunostain, Technical Component Only
Aiding in subtyping intraductal papillary mucinous neoplasms
MSMN - Overview: Membranous Nephropathy Target Antigen Identification, Mass Spectrometry, Tissue
Identification of antigen in membranous nephropathy
PKU - Overview: Phenylalanine and Tyrosine, Plasma
Monitoring effectiveness of dietary therapy in patients with hyperphenylalaninemia
PAX8 - Overview: PAX8 Immunostain, Technical Component Only
Aids in the identification of renal cell carcinomas, as well as papillary thyroid carcinomas and tumors of Mullerian origin
P53 - Overview: p53 Immunostain, Technical Component Only
Aiding in the identification of neoplastic cells
A1APP - Overview: Alpha-1-Antitrypsin Phenotype, Serum
Identification of homozygous and heterozygous phenotypes of the alpha-1-antitrypsin deficiency
LAPYP - Overview: Lactate Pyruvate Panel, Plasma
Diagnosing and monitoring patients with lactic acidosis Monitoring lactate-to-pyruvate ratios
ANAP - Overview: Anaplasma phagocytophilum (Human Granulocytic Ehrlichiosis) Antibody, Serum
As an adjunct in the diagnosis of human granulocytic ehrlichiosis (anaplasmosis) Seroepidemiological surveys of the prevalence of the infection in certain populations
BABG - Overview: Babesia microti IgG Antibodies, Serum
An adjunct in the diagnosis of babesiosis Follow-up of documented babesiosis
BFCC - Overview: Cell Count and Differential, Body Fluid
Aiding in the diagnosis of joint disease, systemic disease, inflammation, malignancy, infection, and trauma
CYTNG - Overview: Cytology Non-Gynecologic, Varies
Detecting malignant and premalignant changes
CL_F - Overview: Chloride, Feces
Workup of cases of chronic diarrhea Evaluation of suspected chloridorrhea
HICSF - Overview: Histoplasma Antibody Complement Fixation and Immunodiffusion, Spinal Fluid
Aiding in the diagnosis of Histoplasma meningitis using spinal fluid specimens
EHRC - Overview: Ehrlichia chaffeensis (HME) Antibody, IgG, Serum
An adjunct in the diagnosis of ehrlichiosis Seroepidemiological surveys of the prevalence of the infection in certain populations
NF4FS - Overview: Neurofascin-155 IgG4, Flow Cytometry, Serum
Evaluating patients with an underlying demyelinating neuropathy Diagnosis of a neurofascin-155 IgG4 mediated neuropathy
PLA2I - Overview: Phospholipase A2 Receptor, Immunofluorescence, Serum
Distinguishing primary from secondary membranous nephropathy in patients with low levels of anti-phospholipase A2 receptor (PLA2R) antibodies Screening for anti-PLA2R antibodies Monitoring patients with membranous nephropathy at very...
Identification of neoplasms expressing programmed cell death 1-ligand 1 (clone SP263)
CPAPS - Overview: Conventional Smear-Screen, Varies
Screening for cervical carcinoma and a number of infections of the female genital tract including human papillomavirus, herpes, Candida, and Trichomonas
Since the pandemic hit, she's spent a great deal of time vetting antibody tests and has set up a COVID-19 testing program at Mayo Clinic....
Staffing to Workload in Phlebotomy Areas: Off-Site Operational Needs - Insights
discusses staffing to workload in phlebotomy areas with a focus on off-site operational needs, including paid time off and unpaid time off....
practices from the program, Mayo Medical Laboratories collaborated with National Decision Support Company (NDSC) to combine Mayo’s clinical knowledge with NDSC’s industry-leading expertise in electronic...
Laboratory and pathology research roundup: August 30 - Insights
This week's research roundup features: Kidney biopsy chronicity grading in antineutrophil cytoplasmic antibody-associated vasculitis...
Visit Mayo Clinic Laboratories at the APA Annual Meeting - Insights
Visit Mayo Clinic Laboratories at booth #2047 to learn about our comprehensive therapeutics test offerings. Developed by board-certified experts in clinical chemistry, molecular, and toxicology testing...