FACYS - Overview: Acyclovir, Plasma
Acyclovir, Plasma
FMELA - Overview: Melatonin, Plasma
Melatonin, Plasma
FNAD - Overview: Nadolol, Serum/Plasma
Nadolol, Serum/Plasma
PNZN - Overview: Perphenazine, Serum or Plasma
Perphenazine, Serum or Plasma
OIBFG - Overview: Osteogenesis Imperfecta and Bone Fragility Gene Panel, Varies
Providing a genetic evaluation for patients with a personal or family history suggestive osteogenesis imperfecta and other hereditary conditions associated with bone fragility
VIRID - Overview: Viral Susceptibility, Defects in Intrinsic and Innate Immunity, Gene Panel, Varies
Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of an inborn error of immunity causing a hereditary form of severe viral susceptibility Establishing a diagnosis of hereditary form of...
UCDP - Overview: Urea Cycle Disorders Gene Panel, Varies
Follow up for abnormal biochemical results suggestive of a urea cycle disorder (UCD) Establishing a molecular diagnosis for patients with a UCD Identifying variants within genes known to be associated with UCD, allowing for predictive...
GSDGP - Overview: Glycogen Storage Disease Gene Panel, Varies
Follow up of abnormal biochemical results consistent with glycogen storage disease (GSD) Establishing a molecular diagnosis for patients with GSD Identifying variants within genes known to be associated with GSD allowing for predictive...
MSUDP - Overview: Maple Syrup Urine Disease Gene Panel, Varies
Follow up for abnormal biochemical results suggestive of maple syrup urine disease (MSUD) Establishing a molecular diagnosis for patients with MSUD Identifying variants within genes known to be associated with MSUD, allowing for...
HIAAP - Overview: 5-Hydroxyindoleacetic Acid, Plasma
Biochemical diagnosis and monitoring of intestinal carcinoid syndrome using a plasma specimen
THYR - Overview: Thyroglobulin Immunostain, Technical Component Only
Classification of thyroid carcinoma
6MAMU - Overview: 6-Monoacetylmorphine Confirmation, Random, Urine
Determination of heroin use
VANPA - Overview: Vancomycin, Peak, Serum
Monitoring peak levels in selected patients receiving vancomycin therapy
PCAB - Overview: Parietal Cell Antibodies, IgG, Serum
Evaluating patients suspected of having pernicious anemia or autoimmune-mediated deficiency of vitamin B12 with or without megaloblastic anemia
CYCPK - Overview: Cyclosporine, Peak, Blood
Monitoring whole blood peak cyclosporine concentration during therapy, particularly in individuals coadministered cytochrome P450 (CYP) 3A4 substrates, inhibitors, or inducers Adjusting dose to optimize immunosuppression while minimizing...
TOPI - Overview: Topiramate, Serum
Monitoring serum concentrations of topiramate Assessing compliance Assessing potential toxicity
INS - Overview: Insulin, Serum
Diagnosing insulinoma, when used in conjunction with proinsulin and C-peptide measurements Management of diabetes mellitus
AMPHU - Overview: Amphetamines Confirmation, Random, Urine
Confirming drug exposure involving amphetamines such as amphetamine and methamphetamine, phentermine, pseudoephedrine/ephedrine, methylenedioxyamphetamine (MDA), and methylenedioxymethamphetamine (MDMA)
AMS - Overview: Amylase, Total, Serum
Diagnosis and management of pancreatitis Evaluation of pancreatic function
BRUTA - Overview: Brucella Total Antibody Confirmation, Agglutination, Serum
Diagnosis of brucellosis
CYSR - Overview: Cystinuria Profile, Quantitative, Random, Urine
Biochemical diagnosis of cystinuria using random urine specimens
CYSPR - Overview: Cyclosporine, Blood
Monitoring whole blood cyclosporine concentration during therapy, particularly in individuals coadministered cytochrome P450 (CYP) 3A4 substrates, inhibitors, or inducers Adjusting dose to optimize immunosuppression while minimizing...
PLA2I - Overview: Phospholipase A2 Receptor, Immunofluorescence, Serum
Distinguishing primary from secondary membranous nephropathy in patients with low levels of anti-phospholipase A2 receptor (PLA2R) antibodies Screening for anti-PLA2R antibodies Monitoring patients with membranous nephropathy at very...
SEMA3 - Overview: Semaphorin 3B (SEMA3B) Immunostain, Technical Component Only
Aiding in the diagnosis of semaphorin 3B-associated membranous nephropathy
MSTC1 - Overview: Strict Criteria Sperm Morphology for Infertility Diagnosis and Treatment, Semen
Diagnosing male infertility Selecting the most cost-effective therapy for treating male-factor infertility Quantifying the number of germinal and WBCs per mL of semen
TRYPP - Overview: Tryptophan, Plasma
Investigating inadequate tryptophan intake and monitoring dietary treatment
CLOBZ - Overview: Clobazam and Metabolite, Serum
Monitoring clobazam therapy
THCU - Overview: Delta-8 and Delta-9-Carboxy-Tetrahydrocannabinol (THC) Confirmation, Random, Urine
Detection and confirmation of drug use of cannabis/marijuana and to specifically identify and quantify delta-8-carboxy tetrahydrocannabinol (THC-COOH) and delta-9-THC-COOH
MMPM - Overview: Mumps Virus Antibody, IgM, Serum
Laboratory diagnosis of mumps virus infection
VANTA - Overview: Vancomycin, Trough, Serum
Preferred test for monitoring vancomycin therapy Monitoring trough concentrations drawn at steady-state in selected patients receiving vancomycin therapy
VANRA - Overview: Vancomycin, Random, Serum
Monitoring adequacy of drug concentration during vancomycin therapy whenever a specimen is submitted or collected without collection timing information
SCCA - Overview: Squamous Cell Carcinoma Antigen, Serum
Aiding in the evaluation and monitoring of squamous cell carcinoma of the head and neck, lung, and cervix This test should not be used to screen for carcinoma or other disorders including those of the liver, lung, or skin.
SOD1Z - Overview: SOD1 Gene, Full Gene Analysis, Varies
Establishing a molecular diagnosis for patients with amyotrophic lateral sclerosis (ALS) Identifying variants within SOD1 known to be associated with ALS, allowing for predictive testing of at-risk family members
CHIMU - Overview: Chimerism Transplant No Cell Sort, Varies
Determining the relative amounts of donor and recipient cells in a specimen An indicator of bone marrow transplant success
MCLNR - Overview: MayoComplete Lung Rearrangements, Rapid Test, Tumor
Identifying lung tumors that may respond to targeted therapies by simultaneously assessing multiple genes involved in rearrangements resulting in fusion transcripts Diagnosing and managing patients with lung cancer
SEP9Z - Overview: SEPTIN9 Gene, Full Gene Analysis, Varies
Establishing a molecular diagnosis for patients with hereditary neuralgic amyotrophy Identifying variants within SEPTIN9 known to be associated with hereditary neuralgic amyotrophy, allowing for predictive testing of at-risk family members
Screening for infection with high-risk human papillomavirus (HPV) associated with the development of cervical cancer Individual genotyping of HPV-16 and/or HPV-18 if present This testing is intended for use in clinical monitoring and...
HEXAZ - Overview: Tay-Sachs Disease, HEXA Gene, Full Gene Analysis, Varies
Second-tier test for confirming a biochemical diagnosis of Tay-Sachs disease (TSD) Carrier testing of individuals with a family history of TSD but an affected individual is not available for testing or disease-causing mutations have not...
WNMC - Overview: West Nile Virus Antibody, IgM, Spinal Fluid
Aids in diagnosing central nervous system West Nile virus infections during the acute phase
ETGX - Overview: Ethyl Glucuronide Confirmation, Chain of Custody, Random, Urine
Monitoring abstinence in clinical and justice system settings using ethyl glucuronide and ethyl sulfate as direct biomarkers or metabolites of ethanol This chain-of-custody test is intended to be used in a setting where the test results...
AHDV - Overview: Hepatitis D Virus Total Antibodies, Serum
Detection of hepatitis D virus (HDV)-specific total antibodies (combined IgG and IgM) in human serum Diagnosis of concurrent HDV infection in patients with fulminant acute hepatitis B virus (HBV) infection (acute coinfection), chronic HBV...
RISA - Overview: Risankizumab, Serum
Assessing the response to risankizumab therapy Assessing the need for dose escalation Evaluating potential changes or discontinuation of therapy Monitoring patients who need to be above a certain risankizumab concentration to improve the...
ROXUR - Overview: Oxalate, Random, Urine
Monitoring therapy for kidney stones using random urine specimens Identifying increased urinary oxalate as a risk factor for stone formation Diagnosis of primary or secondary hyperoxaluria
HEVML - Overview: Hepatitis E Virus IgM Antibody Confirmation, Serum
Confirmation of reactive hepatitis E virus IgM antibody screening test results for the diagnosis of acute or recent (<6 months) hepatitis E infection
UHBAG - Overview: Histoplasma and Blastomyces Antigen, Enzyme Immunoassay, Urine
Diagnosing Histoplasma capsulatum or Blastomyces dermatitidis infection without differentiation between the organisms Monitor antigen levels following initiation of antifungal treatment
TULM - Overview: Francisella tularensis Antibody, IgM, ELISA, Serum
Evaluating the presence of IgM antibodies in patients with suspected tularemia caused by Francisella tularensis This test should not be used as a test of cure as it is not quantitative. Patients may remain seropositive for months to years...
TULG - Overview: Francisella tularensis Antibody, IgG, ELISA, Serum
Evaluating the presence of IgG antibodies in patients with suspected tularemia caused by Francisella tularensis This test should not be used as a test of cure as it is not quantitative. Patients may remain seropositive for months to years...
BILI3 - Overview: Bilirubin, Serum
Assessing liver function Evaluating a wide range of diseases affecting the production, uptake, storage, metabolism, or excretion of bilirubin Monitoring the efficacy of neonatal phototherapy
MRDMM - Overview: Multiple Myeloma Minimal Residual Disease, Flow Cytometry, Bone Marrow
Detecting low level (minimal residual disease) myeloma cells after therapy.
SLO - Overview: Smith-Lemli-Opitz Screen, Plasma
Diagnosing Smith-Lemli-Opitz syndrome (7-dehydrocholesterol reductase deficiency)
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Detection of (1→3)-𝝱-D-glucan as a Marker of Invasive Fungal Disease - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....