SHRI - Overview: Shrimp, IgE, Serum
Establishing a diagnosis of an allergy to shrimp Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm sensitization prior to...
EM - Overview: Electron Microscopy, Varies
Providing information to aid in the diagnosis of medical disorders such as storage diseases, CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy), and primary ciliary dyskinesia
ORTHP - Overview: Orthostatic Proteinuria, Random, Urine
Diagnosis of orthostatic proteinuria
PARVI - Overview: Parvovirus Immunostain, Technical Component Only
Identification of parvovirus infection
PTH - Overview: Parathyroid Hormone (PTH) Immunostain, Technical Component Only
Identification of parathyroid glands
P40 - Overview: p40 Immunostain, Technical Component Only
Diagnosis and classification of carcinomas and lymphomas
P16 - Overview: p16 (INK4a/CDKN2A) Immunostain, Technical Component Only
Aids in the identification of human papilloma virus infection
RSVAB - Overview: Respiratory Syncytial Virus (RSV) In Situ Hybridization, Technical Component Only
Aids in the identification of respiratory syncytial viral infection
CD103 - Overview: CD103 Immunostain, Technical Component Only
Aids in the diagnosis of hairy cell leukemia and marginal zone lymphomas
CTSK - Overview: Cathepsin K Immunostain, Technical Component Only
Evaluation for perivascular epithelioid cell neoplasms (PEComas), alveolar soft part sarcoma, and translocation-associated renal cell carcinomas
TBET - Overview: T-Box Expressed in T Cells (TBET) Immunostain, Technical Component Only
Classification of lymphomas
HPYL - Overview: Helicobacter pylori (H pylori) Immunostain, Technical Component Only
Aiding in the identification of Helicobacter pylori infection
HAD - Overview: Huntington Disease, Molecular Analysis, Varies
Molecular confirmation of clinically suspected cases of Huntington disease (HD) Presymptomatic testing for individuals with a family history of HD and a documented expansion in the HTT gene
HMB45 - Overview: HMB45 Immunostain, Technical Component Only
Identification of activated and neoplastic melanocytes
HEPBS - Overview: Hepatitis B Surface (HBs) Antigen Immunostain, Technical Component Only
Aiding in the identification of hepatitis B infection (carrier state)
GLYCC - Overview: Glycine Receptor Alpha1 IgG, Cell Binding Assay, Spinal Fluid
Evaluating patients with suspected autoimmune stiff-person spectrum disorders (stiff-person syndrome, stiff-limb, stiff trunk, or progressive encephalomyelitis with rigidity and myoclonus [PERM]) using spinal fluids specimens
GRANB - Overview: Granzyme B Immunostain, Technical Component Only
Classification of lymphomas
GLYCF - Overview: Glycophorin A (CD235a) Immunostain, Technical Component Only
Aiding in the identification of erythroid precursors in bone marrow
GAL1 - Overview: GALAD Score, Serum
Calculation of the GALAD (gender, age, alpha-fetoprotein L3% [AFP-L3], AFP, des-gamma-carboxy prothrombin) model score for hepatocellular carcinoma development in patients with chronic liver disease
GCDF - Overview: GCDFP-15 Immunostain, Technical Component Only
Aiding in the identification of extramammary Paget disease, carcinomas of the salivary glands, sweat glands, and prostate
H1083 - Overview: HIK1083 Immunostain, Technical Component Only
Diagnosis of gastric-type endocervical adenocarcinoma
KM55 - Overview: Galactose Deficient IgA1 (KM55) Immunostain, Technical Component Only
Identification of Galactose deficient IgA1 by KM55, useful in the diagnosis of IgA nephropathy
GLYCS - Overview: Glycine Receptor Alpha1 IgG, Cell Binding Assay, Serum
Evaluating patients with suspected autoimmune stiff-person spectrum disorders (stiff-person syndrome, stiff-limb, stiff trunk or progressive encephalomyelitis with rigidity and myoclonus [PERM]) using serum specimens
EMAI - Overview: Epithelial Membrane Antigen (EMA) Immunostain, Technical Component Only
Recognizing epithelial derivation of poorly differentiated malignant tumors Subtyping intraductal papillary mucinous neoplasms when used in conjunction with mucin (MUC) 2, MUC5AC and MUC6
ECADB - Overview: E-Cadherin Immunostain, Bone Marrow, Technical Component Only
Differentiation between lobular and ductal neoplasms of the breast
EBV - Overview: Epstein-Barr Virus (EBV) In Situ Hybridization, Technical Component Only
Detection of Epstein-Barr virus (EBV)-encoded RNA in the diagnosis of EBV-associated conditions
ETGSR - Overview: Ethyl Glucuronide Screen with Reflex, Random, Urine
Screening for drug abuse involving alcohol
LEPDT - Overview: Leptospira, IgM, Serum
Aiding in the diagnosis of leptospirosis This test is not useful for establishing cure or response to therapy.
ICOSI - Overview: ICOS (CD278), Immunostain, Technical Component Only
Classification of T-cell lymphomas
IGGI - Overview: IgG Immunostain, Technical Component Only
Classification of lymphomas and multiple myeloma
IGDI - Overview: IgD Immunostain, Technical Component Only
Aids in the classification of lymphomas and multiple myeloma
IGG4I - Overview: IgG4 Immunostain, Technical Component Only
Identification of IgG4-positive plasma cells in the tissue of patients with systemic autoimmune or allergic manifestations
KKBRP - Overview: Kingella kingae, Molecular Detection, PCR, Blood
Aiding in the diagnosis of Kingella kingae infection using whole blood specimens
INSUL - Overview: Insulin Immunostain, Technical Component Only
Identification of normal pancreatic islet beta cells and insulin secreting islet cell tumors
MMAP - Overview: Methylmalonic Acid, Quantitative, Plasma
Evaluating children with signs and symptoms of methylmalonic acidemia using plasma specimens Evaluating individuals with signs and symptoms associated with a variety of causes of vitamin B12 (cobalamin) deficiency
MMAU - Overview: Methylmalonic Acid, Quantitative, Urine
Evaluating children with signs and symptoms of methylmalonic acidemia using urine specimens Evaluating individuals with signs and symptoms associated with a variety of causes of vitamin B12 (cobalamin) deficiency
MMAS - Overview: Methylmalonic Acid, Quantitative, Serum
Evaluating children with signs and symptoms of methylmalonic acidemia using serum specimens Evaluating individuals with signs and symptoms associated with a variety of causes of vitamin B12 (cobalamin) deficiency
AIVC - Overview: Aldosterone, Inferior Vena Cava, Serum
Investigation using inferior vena cava specimen for: -Primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) -Secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure...
APRAV - Overview: Aldosterone, Right Adrenal Vein, Plasma
Investigation using right adrenal vein plasma specimen for: -Primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) -Secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac...
APLAV - Overview: Aldosterone, Left Adrenal Vein, Plasma
Investigation using left adrenal vein plasma specimen for: -Primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) -Secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac...
ABCRS - Overview: Alpha/Beta Crystallin IHC, Technical Component Only
Characterization of neuroectodermal tumors
ARAV - Overview: Aldosterone, Right Adrenal Vein, Serum
Investigation using right adrenal vein specimen for: -Primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) -Secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure...
ALAV - Overview: Aldosterone, Left Adrenal Vein, Serum
Investigation using left adrenal vein specimen for: -Primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) -Secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure...
ABTIR - Overview: Antibody Titer, Blood and Serum
Monitoring antibody levels during pregnancy to help assess the risk of hemolytic disease of the newborn This test is not useful for monitoring the efficacy of Rh-immune globulin administration.
BXMPL - Overview: Box Elder/Maple, IgE, Serum
Establishing a diagnosis of an allergy to box elder/maple Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm sensitization...
CARBG - Overview: Carbamazepine-10,11-Epoxide, Serum
Monitoring patients exhibiting symptoms of carbamazepine toxicity whose total serum carbamazepine concentration is within the therapeutic range, but who may be producing significant levels of the active metabolite epoxide, which can...
FACTV - Overview: Coagulation Factor V Activity Assay, Plasma
Diagnosing congenital deficiencies (rare) of coagulation factor V Evaluating acquired deficiencies associated with liver disease, factor V inhibitors, myeloproliferative disorders, and intravascular coagulation and fibrinolysis...
CALRC - Overview: Calreticulin ex9mut Immunostain, Technical Component Only
Identifying the presence of CALR exon 9 frameshift alterations in myeloproliferative neoplasms
CD56 - Overview: CD56 Immunostain, Technical Component Only
Aiding in the identification of tumors with neuroendocrine differentiation Aiding in the identification of natural killer cell lineage in a subset of lymphomas
CD71 - Overview: CD71 Immunostain, Technical Component Only
Assessment of erythroid lineage
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....
Week in Review: November 1 - Insights
Top highlights include: Facebook launches into the digital space of healthcare, medical breakthrough for Ebola, and how the brain makes memories.