RBR - Overview: Retinol-Binding Protein, Random, Urine

Assessing renal tubular injury or dysfunction using random urine collections Screening for other tubular abnormalities Detecting chronic asymptomatic renal tubular dysfunction.(2)

GAL2 - Overview: Probability of Hepatocellular Carcinoma, Serum

Calculation of the risk for patients with chronic liver disease to develop hepatocellular carcinoma

CDKP1 - Overview: CD68 (KP1) Immunostain, Tissue, Technical Component Only

Aiding in the identification of histocytic and myeloid lineage cells

P63 - Overview: p63 Immunostain, Technical Component Only

Aiding in identifying squamous, urothelial, or myoepithelial differentiation in tumors

SORD - Overview: Sorbitol and Xylitol, Quantitative, Random, Urine

Screening for sorbitol dehydrogenase deficiency-related neuropathy

WEEPC - Overview: Western Equine Encephalitis Antibody Panel, IgG and IgM, Spinal Fluid

Aiding in the diagnosis of Western equine encephalitis using spinal fluid specimens

SMAT - Overview: Smooth Muscle Antibody Titer, Serum

Antibody titer testing as a part of the evaluation of patients with hepatitis of unknown origin associated with hypergammaglobulinemia and/or abnormal liver enzymes

HEMMF - Overview: Hematologic Specified FISH, Varies

The detection of specific chromosomal abnormalities in hematologic malignancies

HEVG - Overview: Hepatitis E Virus IgG Antibody, Serum

Diagnosis of past exposure to hepatitis E virus

HEG1 - Overview: HEG1 Immunostain, Technical Component Only

Diagnosis of epithelioid mesothelioma versus non-small cell carcinoma

GBM - Overview: Glomerular Basement Membrane Antibodies, IgG, Serum

Evaluating patients with clinical features of anti-glomerular basement disease, including rapidly progressive glomerulonephritis or pulmonary hemorrhage

GASTN - Overview: Gastrin Immunostain, Technical Component Only

Characterization of islet cell tumors and endocrine tumors of the gastrointestinal tract

FASC - Overview: Fascin Immunostain, Technical Component Only

Classification of lymphomas

BFOS - Overview: FosB, Immunostain, Technical Component Only

Diagnosing pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma and epithelioid hemangiomas

3FBLN - Overview: Fibulin 3 Immunostain, Technical Component Only

Identification and classification of amyloid types in tissue

EMICZ - Overview: Emicizumab, Modified One Stage Assay Factor VIII, Plasma

Monitoring compliance or potential development of an antidrug antibody This assay is not indicated for monitoring factor VIII infusions or for making a diagnosis of hemophilia.

LFABP - Overview: Liver Fatty Acid-Binding Protein (L-FABP) Immunostain, Technical Component Only

Classification of hepatic adenomas

ACHE_ - Overview: Acetylcholinesterase, Amniotic Fluid

Diagnosing open neural tube defects and, to a lesser degree, ventral wall defects

ALKOT - Overview: Anaplastic Lymphoma Kinase (ALK [OTI1A4]) Immunostain, Technical Component Only

Identification of anaplastic lymphoma kinase overexpression Diagnosis of inflammatory myofibroblastic tumor and anaplastic large cell lymphoma

B2MC - Overview: Beta-2-Microglobulin (Beta-2-M), Spinal Fluid

Evaluation of central nervous system inflammation and B-cell proliferative diseases

BILIT - Overview: Bilirubin, Total, Serum

Assessing liver function Evaluating a wide range of diseases affecting the production, uptake, storage, metabolism, or excretion of bilirubin Monitoring the efficacy of neonatal phototherapy

C4U - Overview: C4 Acylcarnitine, Quantitative, Random, Urine

Evaluation of patients with abnormal newborn screens showing elevations of iso-/butyrylcarnitine to aid in the differential diagnosis of short-chain acyl-CoA dehydrogenase and isobutyryl-CoA dehydrogenase deficiencies

C9FX - Overview: C9 Complement, Functional, Serum

Diagnosis of C9 deficiency Investigation of a patient with a low total (hemolytic) complement level

MUSK - Overview: Muscle-Specific Kinase (MuSK) Autoantibody, Serum

Diagnosis of autoimmune muscle-specific kinase (MuSK) myasthenia gravis Second-order test to aid in the diagnosis of autoimmune myasthenia gravis when first-line serologic tests are negative Establishing a quantitative baseline value...

SOMAT - Overview: Somatostatin Immunostain, Technical Component Only

Aids in the characterization of pancreatic islet cell tumors or other neuroendocrine tumors

TACPK - Overview: Tacrolimus, Peak, Blood

Assessment of postdosing (peak) blood tacrolimus concentrations

CAVPC - Overview: California Virus (La Crosse) Encephalitis Antibody Panel, IgG and IgM, Spinal Fluid

Aiding in the diagnosis of California (La Crosse) encephalitis using spinal fluid specimens

CARF - Overview: Carbamazepine, Free, Serum

Monitoring unbound or free carbamazepine levels in patients where the total carbamazepine result is within the therapeutic range, but the patient is experiencing side effects Monitoring carbamazepine (free) therapy in patients who are...

DEXT - Overview: Dermatopathology Consultation, Wet Tissue

Histologic diagnosis and differential diagnosis of cutaneous diseases

DIG - Overview: Digoxin, Serum

Monitoring digoxin therapy

DNJB9 - Overview: DNAJB9 Immunostain, Technical Component Only

Diagnosis of fibrillary glomerulonephritis

PD2T - Overview: Pompe Disease Second-Tier Newborn Screening, Blood Spot

Second-tier testing of newborns with an abnormal primary screening result for Pompe disease (decreased acid alpha-glucosidase enzyme activity) Follow-up testing for evaluation of an abnormal newborn screening result for Pompe disease

TLPDF - Overview: T-Cell Lymphoma, Diagnostic FISH, Varies

Detecting, at diagnosis, common chromosome abnormalities associated with specific T-cell lymphoma subtypes using a laboratory-designated probe set algorithm

MPS1R - Overview: Endogenous Mucopolysaccharidosis Type I (IDUA [Alpha-L-Iduronidase]) Biomarker Reflex, Blood Spot

Second-tier testing of newborns with an abnormal primary screening result for mucopolysaccharidosis type I (MPS I, decreased alpha-L-iduronidase activity) where quantitation of the glycosaminoglycans dermatan and heparan sulfate is desired...

MPS2R - Overview: Endogenous Mucopolysaccharidosis Type II (I2S [Iduronate-2-Sulfatase]) Biomarker Reflex, Blood Spot

Second-tier testing of newborns with an abnormal primary screening result for mucopolysaccharidosis type II (MPS II, decreased iduronate-2-sulfatase) where quantitation of the glycosaminoglycans dermatan and heparan sulfate is desired in...

BAMRP - Overview: Bile Acids Malabsorption Panel, Serum and Feces

Aiding in the evaluation of patients suspected of having chronic diarrhea symptoms due to bile acid malabsorption

GNHMA - Overview: Hemophilia A, F8 Gene, Next-Generation Sequencing, Varies

Confirming a clinical diagnosis of hemophilia A in affected male patients with the identification of a disease-causing variant in the F8 gene Determining the disease-causing alteration within the F8 gene to delineate the underlying...

FLUC - Overview: 5-Flucytosine, Serum

Monitoring serum concentration during therapy Evaluating potential toxicity May aid in evaluating patient compliance

ROC - Overview: Rubeola (Measles) Antibodies, IgG and IgM, Spinal Fluid

Diagnosing central nervous system rubeola (measles) virus infection and/or subacute sclerosing panencephalitis

NEFA - Overview: Free Fatty Acids, Total, Serum

Evaluation of metabolic status of patients with endocrinopathies Monitoring of control of diabetes mellitus Monitoring the effects of therapeutic diet/exercise lifestyle changes

METR1 - Overview: Cytochrome b5 Reductase Enzyme Activity, Blood

Evaluation of patients with cyanosis Confirming cases of suspected cytochrome b5 reductase (methemoglobin reductase) deficiency Functional studies in families with cytochrome b5 reductase deficiency

MEPHS - Overview: Mephobarbital and Phenobarbital, Serum

Monitoring of mephobarbital and phenobarbital therapy

GNHTC - Overview: Hereditary Thrombocytopenia Gene Panel, Next-Generation Sequencing, Varies

Evaluating hereditary thrombocytopenia disorders in patients with a personal or family history suggestive of a hereditary thrombocytopenia disorder Diagnosing hereditary thrombocytopenia disorders for patients in whom phenotypic testing is...

C2AD2 - Overview: PrecivityAD2, Plasma

Assisting in the evaluation of adult patients, aged 55 years and older, with signs or symptoms of mild cognitive impairment or dementia who are being assessed for Alzheimer disease and other causes of cognitive decline This is not intended...

STK1Z - Overview: Peutz-Jeghers Syndrome, STK11, Full Gene Analysis, Varies

Evaluating patients with a personal or family history suggestive of Peutz-Jeghers syndrome (PJS) Establishing a diagnosis of PJS allowing for targeted cancer surveillance based on associated risks Identifying variants within genes known...

QFT4 - Overview: QuantiFERON-TB Gold Plus, Blood

Indirect test for Mycobacterium tuberculosis infection, to be used in conjunction with risk assessment, radiography, and other medical and diagnostic evaluations This test is not recommended for use for diagnosis of active tuberculosis...

LRCCZ - Overview: Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome, FH, Full Gene Analysis, Varies

Evaluating patients with a personal or family history suggestive of hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome or fumarate hydratase deficiency (FHD) Establishing a diagnosis of HLRCC or FHD allowing for targeted...

HBABY - Overview: Hepatitis B Virus Perinatal Exposure Follow-up Panel, Serum

Determining hepatitis B virus infection and immunity status (with or without perinatal prophylaxis) in infants born to mothers with chronic hepatitis B

CMPRE - Overview: Family Member Comparator Specimen for Exome Sequencing, Varies

Submitting a biological family member's specimen to be used as a comparator for affected patients (probands) undergoing whole exome sequencing

BAP1Z - Overview: BAP1-Tumor Predisposition Syndrome, BAP1 Full Gene Analysis, Varies

Evaluating patients with a personal or family history suggestive of BAP1-tumor predisposition syndrome (BAP1-TPDS) Establishing a diagnosis of BAP1-TPDS allowing for targeted cancer surveillance based on associated risks Identifying...