Test Catalog

Test Id : DEXT

Dermatopathology Consultation, Wet Tissue

Useful For
Suggests clinical disorders or settings where the test may be helpful

Histologic diagnosis and differential diagnosis of cutaneous diseases

Reflex Tests
Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test Id Reporting Name Available Separately Always Performed
LEV2P Level 2 Gross and microscopic No No
LEV3P Level 3 Gross and microscopic No No
LEV4P Level 4 Gross and microscopic No No

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, 1 of the 3 reflex tests will be performed and charged. Appropriate additional stains and other ancillary testing may be performed to determine a diagnosis. These stains and tests will be charged separately.

 

See Pathology Consultation Ordering Algorithm in Special Instructions.

Special Instructions
Library of PDFs including pertinent information and forms related to the test

Method Name
A short description of the method used to perform the test

Formalin-fixed tissues: Process/Embed

Serial sections: Hematoxylin and Eosin Stain/Light Microscopy

Special Stains, when indicated

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

Dermatopathology Consult

Aliases
Lists additional common names for a test, as an aid in searching

Biopsy

DEXT

Skin Biopsy

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, 1 of the 3 reflex tests will be performed and charged. Appropriate additional stains and other ancillary testing may be performed to determine a diagnosis. These stains and tests will be charged separately.

 

See Pathology Consultation Ordering Algorithm in Special Instructions.

Specimen Type
Describes the specimen type validated for testing

Tissue

Necessary Information

Biopsy site, physician's name, and clinical diagnosis are required.

Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Supplies: Dermatopathology Media (T101)

Sources: Skin or oral mucosa

Container/Tube: Regular serum vials with 10% formalin

Specimen Volume: Entire specimen

Collection Instructions: For scalp biopsies when the differential diagnosis includes a scarring alopecia, 2 separate 4-mm punch biopsies are recommended (1 for vertical and 1 for horizontal sections). If a single scalp biopsy is received with the clinical diagnosis of a scarring alopecia, the specimen will be processed with horizontal sections.

Special Instructions
Library of PDFs including pertinent information and forms related to the test

Specimen Minimum Volume
Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

Size needed depends on diagnosis and size of lesion.

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

No specimen should be rejected.

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
Tissue Ambient (preferred)

Useful For
Suggests clinical disorders or settings where the test may be helpful

Histologic diagnosis and differential diagnosis of cutaneous diseases

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, 1 of the 3 reflex tests will be performed and charged. Appropriate additional stains and other ancillary testing may be performed to determine a diagnosis. These stains and tests will be charged separately.

 

See Pathology Consultation Ordering Algorithm in Special Instructions.

Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Dermatopathology involves histologic examination of skin biopsy and oral mucosal specimens.

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Diagnosis and description of microscopic findings

Interpretation
Provides information to assist in interpretation of the test results

Histologic diagnosis is based primarily on interpretation of hematoxylin and eosin-stained sections. Special histochemical stains, such as alcian blue, Giemsa, or periodic acid-Schiff may be necessary in some cases.

 

Interpretation is based on evaluation of patterns including architectural and cytologic details, which are included in a microscopic description.

Cautions
Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Specific diagnosis may require correlation with clinical information.

Clinical Reference
Recommendations for in-depth reading of a clinical nature

1. Lever WF, Schaumburg-Lever G: Histopathology of the Skin. 7th ed. Philadelphia, JB Lippincott; 1990

2. Elder D, Elenitsas R, Rubin A, et al, eds: Atlas of Dermatopathology Synopsis and Atlas of Lever’s Histopathology of the Skin. 4th ed. Lippincott Williams and Wilkins; 2020

Special Instructions
Library of PDFs including pertinent information and forms related to the test

Method Description
Describes how the test is performed and provides a method-specific reference

Formalin-fixed, paraffin-embedded skin biopsy sections are stained and interpreted utilizing a bright-field microscope.(Elder D, Elenitsas R, Rosenbach, M, et al, eds: Histopathology of the Skin. 11th ed. Lippincott Williams and Wilkins; 2014)

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Friday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

2 to 5 days

Specimen Retention Time
Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

Permanently

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

Rochester

Fees
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their Regional Manager. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

Not Applicable

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.

88302 (if appropriate)

88304 (if appropriate)

88305 (if appropriate)

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports