PC1TS - Overview: Purkinje Cell Cytoplasmic Antibody Type 1 (PCA-1) Titer, Serum

Identifying female patients whose subacute cerebellar degeneration or peripheral neuropathy is due to a remote (autoimmune) effect of gynecologic or breast carcinoma Reporting an end titer result from serum specimens

PIPU - Overview: Pipecolic Acid, Random, Urine

Differentiating between disorders of peroxisomal biogenesis (eg, Zellweger syndrome) and disorders with loss of a single peroxisomal function Detecting abnormal elevations of pipecolic acid in urine

RBPG - Overview: Rubella Antibodies, IgG, Serum

Determining immune status to the rubella virus

T821Q - Overview: RUNX1-RUNX1T1 Translocation (8;21), Minimal Residual Disease Monitoring, Quantitative, Varies

Detection of RUNX1-RUNX1T1 gene fusion in acute myeloid leukemia patients at the time of diagnosis Minimal residual disease monitoring during the clinical and therapeutic course of these patients

RNAP - Overview: RNA Polymerase III Antibodies, IgG, Serum

Evaluating patients suspected of having systemic sclerosis as part of systemic sclerosis criteria antibody tests Providing diagnostic and prognostic information in patients with systemic sclerosis

RISA - Overview: Risankizumab, Serum

Assessing the response to risankizumab therapy Assessing the need for dose escalation Evaluating potential changes or discontinuation of therapy Monitoring patients who need to be above a certain risankizumab concentration to improve the...

SALMC - Overview: Salmonella Culture, Feces

Determining whether Salmonella species may be the cause of diarrhea Reflexive testing for Salmonella species from nucleic acid amplification test-positive feces This test is generally not useful for patients hospitalized more than 3...

DHTS - Overview: Dihydrotestosterone, Serum

Monitoring patients receiving 5-alpha reductase inhibitor therapy or chemotherapy Evaluating patients with possible 5-alpha reductase deficiency

EDN - Overview: Eosinophil Derived Neurotoxin, Serum

Evaluating patients suspected to have a condition associated with eosinophilia or hypereosinophilia Evaluating patients with elevated peripheral blood eosinophil counts Managing patients with elevated eosinophil-derived neurotoxin in the...

DASM5 - Overview: Drugs of Abuse Screen, Meconium 5

Identifying amphetamines (and methamphetamines), opiates, phencyclidine, as well as metabolites of cocaine and marijuana in meconium specimens

EAEBV - Overview: Epstein-Barr Virus Early Antigen, IgG, Serum

Diagnosis of Epstein Barr virus (EBV) infectious mononucleosis in cases when heterophile antibody test results are negative and EBV-specific serologic testing is inconclusive Aiding in the diagnosis of type 2 or type 3 nasopharyngeal...

CVRNA - Overview: Candida Vaginitis, Nucleic Acid Amplification RNA, Vaginal

Aiding in the diagnosis of Candida vaginitis This test is not intended for use in medico-legal applications.

CJDEI - Overview: Creutzfeldt-Jakob Disease Evaluation Interpretation, Spinal Fluid

Interpretation of the Creutzfeldt-Jakob Disease Evaluation

CAVP - Overview: California Virus (La Crosse) IgG and IgM, Serum

Aiding the diagnosis of California (La Crosse) encephalitis using serum specimens

CHLG - Overview: Chlamydia IgG, Immunofluorescence, Serum

Assessing IgG antibody levels to aid in the clinical diagnosis of Chlamydia pneumoniae or Chlamydia psittaci infections

CEE52 - Overview: CD52 Cell Expression Evaluation, Varies

Detecting cell-surface antigens on malignant cells that are potential therapeutic antibody targets, specifically CD52 Determining the eligibility of patients for monoclonal antibody therapies Monitoring response to the therapeutic...

CTXP - Overview: Cerebrotendinous Xanthomatosis, Plasma

Evaluating patients with a clinical suspicion of cerebrotendinous xanthomatosis (CTX) using plasma specimens Monitoring of individuals with CTX on chenodeoxycholic acid (CDCA) therapy This test is not useful for the identification of...

FFRWB - Overview: Friedreich Ataxia, Frataxin, Quantitative, Blood

Diagnosing individuals with Friedreich ataxia in whole blood specimens Monitoring frataxin levels in patients with Friedreich ataxia This test is not useful for carrier detection.

PRKAF - Overview: Fibrolamellar Carcinoma, 19p13.1 (PRKACA) Rearrangement, FISH, Tissue

Aid in the diagnosis of identifying PRKACA gene rearrangements of patients with fibrolamellar carcinoma

MMGEN - Overview: Mycoplasma genitalium, Transcription-Mediated Amplification, Post-Prostatic Massage Fluid/Urine or Peritoneal Fluids

Detecting Mycoplasma genitalium in cases of suspected infection in peritoneal fluid or prostatic secretion (VBIII) fluid/urine This test is not intended for use in medico-legal applications.

MTBXS - Overview: Mycobacterium tuberculosis Complex, Molecular Detection and Rifampin Resistance, PCR, Sputum

Rapid detection of Mycobacterium tuberculosis DNA from respiratory specimens for the diagnosis of pulmonary tuberculosis Presumptive detection of rifampin resistance based on the presence of resistance-associated mutations

MPS3W - Overview: Mucopolysaccharidosis III, Four-Enzyme Panel, Leukocytes

Supporting the biochemical diagnosis of mucopolysaccharidoses types IIIA, IIIB, IIIC, IIID This test is not useful for carrier detection.

LAPYP - Overview: Lactate Pyruvate Panel, Plasma

Diagnosing and monitoring patients with lactic acidosis Monitoring lactate-to-pyruvate ratios

LAGU - Overview: Legionella Antigen, Random, Urine

An adjunct to culture for the detection of past or current Legionnaires disease (Legionella pneumophila serogroup 1)

LRBA - Overview: Lipopolysaccharide-Responsive Beige-Like Anchor Protein (LRBA) Deficiency, Blood

Aiding in the diagnosis of lipopolysaccharide-responsive beige-like anchor protein (LRBA) deficiency This test is not useful for identifying a carrier status for LRBA deficiency.

ROM - Overview: Measles (Rubeola) Antibodies, IgM, Serum

Determining acute-phase infection with rubeola (measles) virus using IgM antibody testing Aiding in the identification of nonimmune individuals through IgM antibody testing

UPGC - Overview: Uroporphyrinogen III Synthase (Co-Synthase), Erythrocytes

Diagnosis of congenital erythropoietic porphyria This test is not useful for diagnosis of acute intermittent porphyria (AIP).

UPGD - Overview: Uroporphyrinogen Decarboxylase, Whole Blood

Preferred test for the confirmation of a diagnosis of porphyria cutanea tarda type II and hepatoerythropoietic porphyria

TOXB - Overview: Toxoplasma gondii, Molecular Detection, PCR, Blood

Supporting the diagnosis of active toxoplasmosis, particularly in immunocompromised individuals

SUAC - Overview: Succinylacetone, Blood Spot

Second-tier newborn screen for tyrosinemia type 1 (HT-1) when primary screen showed nonspecific elevations of tyrosine Diagnosing HT-1 when used in conjunction with testing for urine organic acids, liver function, alpha-fetoprotein, and...

TCGRV - Overview: T-Cell Receptor Gene Rearrangement, PCR, Varies

Determining whether a T-cell population is polyclonal or monoclonal using body fluid or tissue specimens

TCGBM - Overview: T-Cell Receptor Gene Rearrangement, PCR, Bone Marrow

Determining whether a T-cell population is polyclonal or monoclonal

VWFMP - Overview: von Willebrand Factor Multimer Analysis, Plasma

As a reflex component of several coagulation consultation unit codes, when indicated When results of complementary laboratory tests are abnormally low or discordant (eg, F8A / Coagulation Factor VIII Activity Assay, Plasma; VWACT / von...

MAMMX - Overview: 6-Monoacetylmorphine (6-MAM) Confirmation, Chain of Custody, Meconium

Detecting in utero heroin exposure up to 5 months before birth Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen...

WNMS - Overview: West Nile Virus Antibody, IgM, Serum

Detection of IgM antibodies in West Nile virus infections

AFP - Overview: Alpha-Fetoprotein (AFP) Tumor Marker, Serum

Follow-up management of patients undergoing cancer therapy, especially for testicular and ovarian tumors and for hepatocellular carcinoma Often used in conjunction with human chorionic gonadotropin.(2) This test is not recommended as a...

PKU - Overview: Phenylalanine and Tyrosine, Plasma

Monitoring effectiveness of dietary therapy in patients with hyperphenylalaninemia

TQ10 - Overview: Coenzyme Q10, Total, Plasma

Diagnosis of primary coenzyme Q10 (CoQ10) deficiencies in some patients who are not supplemented with CoQ10 Monitoring patients receiving statin therapy Monitoring CoQ10 status during treatment of various degenerative conditions,...

AAUCD - Overview: Amino Acids, Urea Cycle Disorders Panel, Plasma

Follow-up of patients with urea cycle disorders

AIAES - Overview: Axonal Neuropathy, Autoimmune/Paraneoplastic Evaluation, Serum

Evaluation of patients who present with a subacute neurological disorder of undetermined etiology, especially those with known risk factors for cancer Directing a focused search for cancer Investigating neurological symptoms that appear...

IPFGP - Overview: Idiopathic Pulmonary Fibrosis Gene Panel, Varies

Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of familial idiopathic pulmonary fibrosis Establishing a diagnosis of familial idiopathic pulmonary fibrosis associated with known...

GIP - Overview: Gastrointestinal Pathogen Panel, PCR, Feces

Rapid detection of gastrointestinal infections caused by: -Campylobacter species (Campylobacter jejuni/Campylobacter coli/Campylobacter upsaliensis) -Clostridioides difficile toxin A/B -Plesiomonas shigelloides -Salmonella species -Vibrio...

NF1Z - Overview: Neurofibromatosis Type 1, NF1, Full Gene Analysis, Varies

Evaluating patients with a personal or family history suggestive of neurofibromatosis type 1 (NF1) Establishing a diagnosis of a NF1 allowing for targeted cancer surveillance based on associated risks Identifying genetic variants...

WESDX - Overview: Whole Exome Sequencing for Hereditary Disorders, Varies

Serving as a first-tier test to identify a molecular diagnosis in patients with suspected genetic disorders, which can allow for: -Better understanding of the natural history/prognosis -Targeted management (anticipatory guidance, management...

HLHGP - Overview: Primary Hemophagocytic Lymphohistiocytosis Gene Panel, Varies

Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of familial hemophagocytic lymphohistiocytosis (F-HLH) Establishing a diagnosis of F-HLH, allowing for appropriate management and...

MITOP - Overview: Mitochondrial Full Genome Analysis, Next-Generation Sequencing (NGS), Varies

Diagnosis of the subset of mitochondrial diseases that result from variants in the mitochondrial genome A second-tier test for patients in whom previous targeted gene variant analyses for specific mitochondrial disease-related genes were...

BABPB - Overview: Babesia species, Molecular Detection, PCR, Blood

Initial screening or confirmatory testing for suspected babesiosis during the acute febrile stage of infection in patients from endemic areas, especially when Giemsa-stained peripheral blood smears do not reveal any organisms, or the...

LADV - Overview: Adenovirus, Molecular Detection, PCR, Varies

Aiding in the diagnosis of adenovirus infections

WBSQR - Overview: Beta-Globin Gene Sequencing, Blood

Evaluating for the following in an algorithmic process for the HAEV1 / Hemolytic Anemia Evaluation, Blood; HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood; MEV1 / Methemoglobinemia Evaluation, Blood; REVE2 / Erythrocytosis Evaluation,...

PBKQN - Overview: BK Virus DNA Detection and Quantification, Plasma

Detection and serial monitoring of BK virus-associated nephropathy in kidney transplant recipients using plasma specimens Detection and serial monitoring of BK virus-associated hemorrhagic cystitis in organ transplant recipients