SHBG1 - Overview: Sex Hormone-Binding Globulin, Serum
Diagnosis and follow-up of women with signs or symptoms of androgen excess (eg, polycystic ovarian syndrome and idiopathic hirsutism) An adjunct in monitoring sex-steroid and antiandrogen therapy An adjunct in the diagnosis of disorders...
SS18F - Overview: Synovial Sarcoma (SS), 18q11.2 (SS18 or SYT) Rearrangement, FISH, Tissue
Supporting the diagnosis of synovial sarcoma when used in conjunction with an anatomic pathology consultation
EFPO - Overview: Electrolyte and Osmolality Panel, Feces
Workup of cases of chronic diarrhea Diagnosis of factitious diarrhea (where patient adds water to stool to simulate diarrhea)
OPE - Overview: Ova and Parasite, Travel History or Immunocompromised, Feces
Detecting and identifying parasitic protozoa and eggs and larvae of parasitic helminths in stool specimens
TPBF - Overview: Protein, Total, Body Fluid
Identification of exudative pleural effusions Differentiating hepatic from other causes of ascites that have elevated serum ascites albumin gradient using peritoneal fluid
T4 - Overview: T4 (Thyroxine), Total Only, Serum
Monitoring treatment with synthetic hormones (synthetic T3 [triiodothyronine] will cause a low total T4 [thyroxine]) Monitoring treatment of hyperthyroidism with thiouracil and other anti-thyroid drugs Index of thyroid function when the...
WEEP - Overview: Western Equine Encephalitis Antibody, IgG and IgM, Serum
Aiding the diagnosis of Western equine encephalitis using serum specimens
VMA - Overview: Vanillylmandelic Acid, 24 Hour, Urine
Screening children for catecholamine-secreting tumors using a 24-hour urine collection when requesting testing for vanillylmandelic acid only Supporting a diagnosis of neuroblastoma Monitoring patients with a treated neuroblastoma
ASMW - Overview: Acid Sphingomyelinase, Leukocytes
Investigation of possible diagnosis of Niemann-Pick disease types A and B This test is not recommended for carrier detection because of the wide range of enzymatic activities observed in carriers and noncarriers.
RIB - Overview: Ribosome P Antibodies, IgG, Serum
As an adjunct in the diagnostic evaluation of patients with systemic lupus erythematosus (SLE) May be useful in the phenotypic stratification of SLE patients at risk for neuropsychiatric SLE, lupus nephritis and/or hepatitis
RNP - Overview: RNP Antibodies, IgG, Serum
Evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive Testing for ribonucleoprotein particle antibodies is not useful in patients without demonstrable...
FRDIG - Overview: Digoxin, Free, Serum
Evaluating recrudescent (breakthrough) digoxin toxicity in renal-failure patients Assessing the need for more antidigoxin Fab to be administered Deciding when to reintroduce digoxin therapy Monitoring patients with possible...
SSB - Overview: SS-B/La Antibodies, IgG, Serum
Evaluating patients with clinical features or at-risk for connective tissue disease, especially Sjögren syndrome.
WNCSF - Overview: West Nile Virus, RNA, PCR, Molecular Detection, Spinal Fluid
Rapid testing for West Nile virus (WNV) RNA (lineage 1 and lineage 2) using cerebrospinal fluid specimens An adjunctive test to serology for detection of early WNV infection (ie, first few days after symptom onset) This assay should not...
T4BPE - Overview: Thyroxine-Binding Protein Electrophoresis, Serum
Explaining unusual thyroxine (T4), free T4, and thyroxine-binding globulin test results that do not correlate with the patient's clinical presentation Detecting the presence of aberrant thyroxine-binding proteins, such as abnormal forms...
INHA - Overview: Inhibin A, Tumor Marker, Serum
Aiding in the diagnosis of patients with granulosa cell tumors of the ovary when used in combination with inhibin B Monitoring of patients with granulosa cell tumors and epithelial mucinous-type tumors of the ovary known to secrete inhibin...
IL6DX - Overview: Interleukin-6, Serum
Evaluating patients with suspected chronic inflammatory disorders, such as rheumatoid arthritis, systemic lupus erythematosus, ankylosing spondylitis, or inflammatory bowel disease Evaluating patients with Castleman disease Evaluating...
LKM - Overview: Liver/Kidney Microsome Type 1 Antibodies, Serum
Evaluation of patients with liver disease of unknown etiology Evaluation of patients with suspected autoimmune hepatitis
LDBF - Overview: Lactate Dehydrogenase (LDH), Body Fluid
Identification of exudative pleural effusions Lactate dehydrogenase in pericardial fluids is not diagnostically useful.
IBDP2 - Overview: Inflammatory Bowel Disease Serology Panel, Serum
Distinguishing between ulcerative colitis and Crohn disease in patients for whom the specific diagnosis is unclear based on endoscopic, pathologic, and imaging evaluations This test is not useful for determining the extent of disease in...
KRASP - Overview: KRAS Somatic Mutation Analysis, Tumor
Detecting molecular markers associated with response or resistance to specific cancer
SFEC - Overview: Iron and Total Iron-Binding Capacity, Serum
Screening for chronic iron overload diseases, particularly hereditary hemochromatosis Screening for iron deficiency as the cause of anemia Monitoring treatment for iron deficiency anemia This test should not be used as the primary test...
JAK2B - Overview: JAK2 V617F Mutation Detection, Blood
Aiding in the distinction between a reactive blood cytosis and a chronic myeloproliferative disorder using peripheral blood specimens
JO1 - Overview: Jo 1 Antibodies, IgG, Serum
Evaluating patients with clinical features of idiopathic inflammatory myositis, especially those with clinical features suggestive of anti-synthetase syndrome or interstitial lung disease
Detecting Mycoplasma genitalium in cases of suspected infection in peritoneal fluid or prostatic secretion (VBIII) fluid/urine This test is not intended for use in medico-legal applications.
Distinguishing between hepatocellular carcinoma and chronic liver disease Monitoring individuals with hepatic cirrhosis from any etiology for progression to hepatocellular carcinoma Surveillance for development of hepatocellular...
AN1TS - Overview: Antineuronal Nuclear Antibody-Type 1 (ANNA-1) Titer, Serum
Diagnosis of paraneoplastic autoimmune neuropathies, encephalomyeloradiculopathies, related neurologic disorders, and intestinal pseudo-obstruction/dysmotility associated with small-cell lung carcinoma Reporting an end titer result from...
Confirming the presence or absence of minimal residual disease in patients with known chronic lymphocytic leukemia who are either post-chemo/immunotherapy or post-bone marrow transplant
PMET - Overview: Metanephrines, Fractionated, Free, Plasma
Screening test for presumptive diagnosis of catecholamine-secreting pheochromocytomas or paragangliomas
CALPR - Overview: Calprotectin, Feces
Evaluating patients suspected of having a gastrointestinal inflammatory process Distinguishing inflammatory bowel disease from irritable bowel syndrome, when used in conjunction with other diagnostic modalities, including endoscopy,...
SLFAT - Overview: Cryptococcus Antigen Titer, Lateral Flow Assay, Serum
Monitoring Cryptococcus antigen titers in serum Aiding in the diagnosis of cryptococcosis This test should not be used as a test of cure or to guide treatment decisions.
CMVP - Overview: Cytomegalovirus (CMV) Antibodies, IgM and IgG, Serum
Aiding in the diagnosis of acute or past infection with cytomegalovirus (CMV) Determining prior exposure to CMV This test should not be used for screening blood or plasma donors.
COWB - Overview: Cobalt, Blood
Monitoring exposure to cobalt using whole blood specimens Monitoring metallic prosthetic implant wear This test is not useful for assessment of vitamin B12 activity.
DHTS - Overview: Dihydrotestosterone, Serum
Monitoring patients receiving 5-alpha reductase inhibitor therapy or chemotherapy Evaluating patients with possible 5-alpha reductase deficiency
DBS1 - Overview: Diabetes Mellitus Type 1 Evaluation, Serum
Distinguishing type 1 from type 2 diabetes mellitus Identifying individuals at risk of type 1 diabetes (including high-risk relatives of patients with diabetes) Predicting future insulin requirement treatment in patients with adult-onset...
PBGDW - Overview: Porphobilinogen Deaminase, Washed Erythrocytes
Confirmation of a diagnosis of acute intermittent porphyria using washed erythrocyte specimens
CIVC - Overview: Cortisol, Inferior Vena Cava, Serum
Testing cortisol levels in the inferior vena cava Second-order testing wen cortisol measurement by immunoassay gives results that are not consistent with clinical symptoms, or if patients are known to, or suspected of, taking exogenous...
JAK2M - Overview: JAK2 V617F Mutation Detection, Bone Marrow
Aiding in the distinction between a reactive blood cytosis and a chronic myeloproliferative disorder using bone marrow specimens
Identification of neoplasms expressing programmed cell death 1-ligand 1 (clone SP263)
PEAR - Overview: Pear, IgE, Serum
Establishing a diagnosis of an allergy to pear Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm sensitization prior to...
PTU - Overview: Protein, Total, 24 Hour, Urine
Evaluation of kidney disease using a 24-hour urine collection Screening for monoclonal gammopathy
THYR - Overview: Thyroglobulin Immunostain, Technical Component Only
Classification of thyroid carcinoma
CAI - Overview: Calcium, Ionized, Serum
Assessing calcium states during liver transplantation surgery, cardiopulmonary bypass, or any procedure requiring rapid transfusion of whole blood in neonates and critically ill patients Second-order test in the evaluation of patients with...
NITF - Overview: Nitrogen, Total, Feces
Determining nitrogen balance, when used in conjunction with 24-hour urine nitrogen measurement Assessing nutritional status (protein malnutrition) Evaluating protein catabolism
UPH24 - Overview: pH, 24 Hour, Urine
Assessment of patients with metabolic acidosis, crystalluria, as well as monitoring the effectiveness of alkalinization or acidification of urine for certain medical conditions (eg, treatment of uric acid nephrolithiasis) using a 24-hour...
POPSD - Overview: Poppy Seed, IgE, Serum
Establishing the diagnosis of an allergy to poppy seed Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm sensitization...
D240 - Overview: Podoplanin (D2-D40) Immunostain, Technical Component Only
Aids in the identification of reactive follicular dendritic cells
CYCPK - Overview: Cyclosporine, Peak, Blood
Monitoring whole blood peak cyclosporine concentration during therapy, particularly in individuals coadministered cytochrome P450 (CYP) 3A4 substrates, inhibitors, or inducers Adjusting dose to optimize immunosuppression while minimizing...
Detecting tripartite motif-containing protein 46 (TRIM46)-IgG by cell-binding assay using cerebrospinal fluid specimens Evaluation of an autoimmune/paraneoplastic neurological syndrome among patients presenting with cerebellar ataxia,...
UPII - Overview: Uroplakin II Immunostain, Technical Component Only
Characterization of urothelial carcinoma
Week in Review: February 3 - Insights
Include: President Biden to End Covid-19 Emergencies On May 11, and Children’s Minnesota Received $3 Million Grant To Address Pediatric Health Disparities....
Leveraging the Laboratory Archives - Page 3 of 3 - Insights
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Detection of (1→3)-𝝱-D-glucan as a Marker of Invasive Fungal Disease - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections....
Phlebotomy Modules: Module 3 | Insights
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Week in Review: March 3 - Insights
Today's Highlights Include: COVID-19 deaths remain low compared to previous winters, FDA authorizing first at-home combo flu/Covid test, and Rochester public schools evaluating mental health needs and services throughout the district.