AFPSF - Overview: Alpha-Fetoprotein (AFP), Spinal Fluid
An adjunct in the diagnosis of central nervous system (CNS) germinomas and meningeal carcinomatosis Evaluating the presence of germ-cell tumors in the CNS, in conjunction with cerebrospinal fluid (CSF) beta-human chorionic gonadotropin...
MCM24 - Overview: Mast Cell Mediators, 24 Hour, Urine
Evaluating patients at risk for mast cell activation syndrome (eg, systemic mastocytosis) using 24-hour urine collections
HEMP - Overview: Hereditary Erythrocytosis Mutations, Whole Blood
Definitive evaluation of an individual with JAK2-negative erythrocytosis associated with lifelong sustained increased red blood cell (RBC) mass, elevated RBC count, hemoglobin, or hematocrit This test is not intended for prenatal...
MP8BS - Overview: Mucopolysaccharidoses, Eight-Enzyme Panel, Blood Spot
Supporting the biochemical diagnosis of mucopolysaccharidoses types II, IIIA, IIIB, IIIC, IVA, IVB, VI, and VII, and of multiple sulfatase deficiency This test is not useful for carrier detection.
NFLP - Overview: Neurofilament Light Chain, Plasma
Assessing neuronal damage related to various neurodegenerative diseases
PTHFN - Overview: Parathyroid Hormone, Fine-Needle Aspiration Biopsy (FNAB)-Needle Wash
Discriminating thyroid tissue from enlarged parathyroid glands Facilitating parathyroid localization prior to surgery An adjunct to cytology examination of fine-needle aspiration specimens to confirm or exclude presence of parathyroid...
LAGU - Overview: Legionella Antigen, Random, Urine
An adjunct to culture for the detection of past or current Legionnaires disease (Legionella pneumophila serogroup 1)
ARSBW - Overview: Arylsulfatase B, Leukocytes
Supporting the biochemical diagnosis of mucopolysaccharidosis type VI (MPS VI, Maroteaux-Lamy syndrome) in whole blood specimens This test is not useful for carrier detection.
BA48F - Overview: Bile Acids, Bowel Dysfunction, 48 Hour, Feces
Aids in evaluation of patients suspected of having irritable bowel syndrome-diarrhea symptoms due to bile acid malabsorption
MNB - Overview: Manganese, Blood
Evaluation of central nervous system symptoms, similar to Parkinson disease, in manganese (Mn) miners and processors Characterization of liver cirrhosis Therapeutic monitoring in treatment of cirrhosis, parenteral nutrition-related Mn...
CRCOF - Overview: Chromium and Cobalt, Synovial Fluid
Monitoring metallic prosthetic implant wear and local tissue destruction in failed hip arthroplasty constructs This test is not useful for assessment of vitamin B12 activity.
CRMTC - Overview: Collapsin Response-Mediator Protein-5 (CRMP-5) Neuronal IgG Titer, Spinal Fluid
Evaluation of neuroautoimmunity, particularly small-cell lung carcinoma and thymoma, in conjunction with other antineuronal antibodies Reporting an end titer result from cerebrospinal fluid specimens
COWB - Overview: Cobalt, Blood
Monitoring exposure to cobalt using whole blood specimens Monitoring metallic prosthetic implant wear This test is not useful for assessment of vitamin B12 activity.
GLSF - Overview: Glucose, Spinal Fluid
Investigating possible central nervous system infection
HBA1C - Overview: Hemoglobin A1c, Blood
Evaluating the long-term control of blood glucose concentrations in patients with diabetes Diagnosing diabetes Identifying patients at increased risk for diabetes (prediabetes) This assay is not useful in determining day-to-day glucose...
WBGDR - Overview: Beta-Globin Gene Cluster Deletion/Duplication, Blood
Determining the etiology of hereditary persistence of fetal hemoglobin (HPFH), delta-beta thalassemia, or other large deletions involving the beta-globin gene cluster Diagnosing less common causes of beta-thalassemia; these large...
CAH2T - Overview: Congenital Adrenal Hyperplasia Newborn Screen, Blood Spot
Second-tier testing of newborns with abnormal screening result for congenital adrenal hyperplasia
DRVI4 - Overview: Dilute Russell's Viper Venom Time (DRVVT) Interpretation
Interpreting mixing and confirmation assays for lupus anticoagulants
RSMPU - Overview: Monoclonal Protein Screen, Random, Urine
Identifying monoclonal gammopathies using random urine specimens
UGTFZ - Overview: UDP-Glucuronosyltransferase 1A1 (UGT1A1), Full Gene Sequencing, Varies
Establishing a diagnosis of Crigler-Najjar syndrome type I or type II and the trait of Gilbert syndrome Establishing carrier status for Crigler-Najjar syndrome type I or type II Identifying individuals who are at risk of...
UOSMU - Overview: Osmolality, Random, Urine
Assessing the concentrating and diluting ability of the kidney
TPSF - Overview: Protein, Total, Spinal Fluid
Detecting disruptions of the blood-brain barrier or intrathecal synthesis of immunoglobulins
FPAN2 - Overview: Pancreastatin, Plasma
Pancreastatin, Plasma
SEWB - Overview: Selenium, Blood
Assessment of tissue stores of selenium
PMMIL - Overview: Phosphomannomutase and Phosphomannose Isomerase, Leukocytes
Diagnosing congenital disorders of glycosylation Ia (phosphomannomutase-2 deficiency: PMM2-CDG) and Ib (phosphomannose isomerase deficiency: MPI-CDG) as measured in leukocytes Follow-up testing for patients with an abnormal type I CDG...
Aiding in the prognosis and clinical management of lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia
MP9W - Overview: Mucopolysaccharidoses, Nine-Enzyme Panel, Leukocytes
Supporting the biochemical diagnosis of mucopolysaccharidoses types II, IIIA, IIIB, IIIC, IIID, IVA, IVB, VI, and VII, and of multiple sulfatase deficiency This test is not useful for carrier detection.
STER - Overview: Sterols, Plasma
Investigation of possible desmosterolosis (desmosterol reductase deficiency), cerebrotendinous xanthomatosis, lathosterolosis, sitosterolemia, sterol C4 methyl oxidase deficiency, MEND (male EBP disorder with neurologic defects) syndrome,...
CELI - Overview: Celiac Associated HLA-DQ Alpha 1 and DQ Beta 1 DNA Typing, Blood
Assessing risk of celiac disease
DRVI2 - Overview: Dilute Russell's Viper Venom Time (DRVVT) Mix Ratio, Plasma
Detecting the presence or helping to exclude the presence of lupus anticoagulants (LA) Identifying LA that do not prolong the activated partial thromboplastin time (APTT) Evaluating unexplained prolongation of the APTT or prothrombin...
HPP - Overview: Pancreatic Polypeptide, Plasma
Detecting pancreatic endocrine tumors Assessing vagal nerve function after meal or sham feeding
GD65C - Overview: Glutamic Acid Decarboxylase (GAD65) Antibody Assay, Spinal Fluid
Possible use in evaluating patients with autoimmune encephalitis, stiff-person syndrome, autoimmune ataxia, autoimmune epilepsy, and other acquired central nervous system disorders affecting gabaminergic neurotransmission
OSM24 - Overview: Osmolality, 24 Hour, Urine
Assessing the concentrating and diluting ability of the kidney using a 24-hour urine collection
ETGS - Overview: Ethyl Glucuronide Screen, Random, Urine
Screening for drug abuse involving alcohol
TFNAB - Overview: Thyroglobulin, Tumor Marker, Fine-Needle Aspiration Biopsy Needle Wash
Confirming or excluding metastases in enlarged or ultrasonographically suspicious lymph nodes from athyrotic individuals treated for differentiated thyroid cancer in conjunction with cytologic analysis Confirming or excluding the presence...
DRVI3 - Overview: Dilute Russell's Viper Venom Time (DRVVT) Confirmation Ratio, Plasma
Confirming the presence or helping to exclude the presence of lupus anticoagulants (LA) Identifying LA that do not prolong the activated partial thromboplastin time (APTT) Evaluating unexplained prolongation of the APTT or prothrombin...
CDGGP - Overview: Congenital Disorders of Glycosylation Gene Panel, Varies
Establishing a molecular diagnosis for patients with congenital disorders of glycosylation Identifying variants within genes known to be associated with congenital disorders of glycosylation, allowing for predictive testing of at-risk...
APHTC - Overview: Amphiphysin Antibody Titer Assay, Spinal Fluid
Evaluating patients with recent onset of a subacute neurological disorder for which a paraneoplastic basis might be suspected, particularly if the patient has a previous history, risk factors, or family history of cancer, especially lung or...
PALD - Overview: Aldosterone, Plasma
Investigation of primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter...
AMYPI - Overview: Amyloid P (SAP) Immunostain, Technical Component Only
Identification of amyloid deposits in tissue
GLYCC - Overview: Glycine Receptor Alpha1 IgG, Cell Binding Assay, Spinal Fluid
Evaluating patients with suspected autoimmune stiff-person spectrum disorders (stiff-person syndrome, stiff-limb, stiff trunk, or progressive encephalomyelitis with rigidity and myoclonus [PERM]) using spinal fluids specimens
FENTU - Overview: Fentanyl with Metabolite Confirmation, Random, Urine
Detection and confirmation of illicit drug use involving fentanyl
ETGSR - Overview: Ethyl Glucuronide Screen with Reflex, Random, Urine
Screening for drug abuse involving alcohol
AFPPT - Overview: Alpha-Fetoprotein (AFP), Peritoneal Fluid
An adjunct to cytology to differentiate between malignancy-related ascites and benign causes of ascites formation
APIVC - Overview: Aldosterone, Inferior Vena Cava, Plasma
Investigation using inferior vena cava plasma specimen for: -Primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) -Secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac...
APRAV - Overview: Aldosterone, Right Adrenal Vein, Plasma
Investigation using right adrenal vein plasma specimen for: -Primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) -Secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac...
APLAV - Overview: Aldosterone, Left Adrenal Vein, Plasma
Investigation using left adrenal vein plasma specimen for: -Primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) -Secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac...
B2MC - Overview: Beta-2-Microglobulin (Beta-2-M), Spinal Fluid
Evaluation of central nervous system inflammation and B-cell proliferative diseases
C5B9 - Overview: SC5b-9 Level Terminal Complement Complex, Plasma
Detecting increased complement activation
MYGLU - Overview: Myoglobin, Random, Urine
Confirming the presence of a myopathy
sequential-maternal-serum-screening-testing-algorithm.pdf
Foundation for Medical Education and Research (MFMER). All rights reserved. Sequential Maternal Serum Screening Testing Algorithm Diagnostic testing should be offered Screen-positive: results reported...
MCL Platelet Antibody Screen Serum Information MC1235242
MCL Platelet Antibody Screen Serum Information Complete print Platelet Antibody Screen Serum Patient Information Reset Form Patient Information Patient Middle Birth Date...
Mayo Clinic Laboratory and Pathology Research Roundup: Nov. 26 - Insights
This week’s Research Roundup highlights the effect of inorganic nitrite versus a placebo on exercise capacity among patients with heart failure with preserved ejection fraction....
Gravis/Lambert-Eaton Myasthenic Syndrome Evaluation, Serum
Confirming the autoimmune basis of a defect in neuromuscular transmission (eg, myasthenia gravis [MG], Lambert-Eaton myasthenic syndrome [LEMS]) Distinguishing LEMS from autoimmune forms of MG Providing a quantitative autoantibody...
Atypical Hemolytic Uremic Syndrome Complement Panel, Serum and Plasma
Detecting deficiencies in the alternative pathway that can cause atypical-hemolytic uremic syndrome, dense deposit disease, and C3 glomerulonephritis A second-tier test that aids in the differential diagnosis of thrombotic...