PNRP - Overview: Pneumocystis jiroveci, Molecular Detection, PCR, Varies

Preferred test for detection of Pneumocystis

PLAIF - Overview: Phospholipase A2 Receptor (PLA2R), Renal Biopsy

Distinguishing primary membranous nephropathy from secondary membranous nephropathy

LPSBF - Overview: Lipase, Body Fluid

Determining whether pancreatic inflammation or pancreatic fistula may be contributing to a pathological accumulation of fluid

BUPS - Overview: Buprenorphine Screen, Random, Urine

Screening for drug abuse or use of buprenorphine

PLINK - Overview: Paroxysmal Nocturnal Hemoglobinuria, PI-Linked Antigen, Blood

Screening for and confirming the diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) Monitoring patients with PNH

MMLSG - Overview: Antimicrobial Susceptibility, Acid-Fast Bacilli, Slowly Growing, Varies

Determination of resistance of slowly growing mycobacteria to antimicrobial agents

17OHP - Overview: 17-Hydroxypregnenolone, Serum

As an ancillary test for congenital adrenal hyperplasia (CAH), particularly in situations in which a diagnosis of both 21- and 11-hydroxylase deficiency have been ruled out Confirming a diagnosis of 3-beta-hydroxysteroid dehydrogenase...

FROPI - Overview: Ropivacaine, Serum/Plasma

Ropivacaine, Serum/Plasma

HEXBZ - Overview: Sandhoff Disease, HEXB Gene, Full Gene Analysis, Varies

Follow up for abnormal biochemical results suggestive of Sandhoff disease Establishing a molecular diagnosis for patients with Sandhoff disease Identifying variants within genes known to be associated with Sandhoff disease, allowing for...

AFXN - Overview: Friedreich Ataxia, Repeat Expansion Analysis, Varies

Molecular confirmation of clinically suspected Friedreich ataxia

APOL1 - Overview: APOL1 Genotype, Varies

Determining an individual's APOL1 genotype This test is not useful for clinical management of individuals with APOL1 risk genotypes. This test alone is not useful for determining eligibility for donation or receipt of kidney...

AMLPF - Overview: Acute Myeloid Leukemia (AML), FISH, Pediatric, Varies

This test should not be used to screen for residual acute myeloid leukemia (AML). Useful at diagnosis for detecting recurrent common chromosome abnormalities in pediatric patients with AML An adjunct to chromosome studies in patients with...

EBVQN - Overview: Epstein-Barr Virus DNA Detection and Quantification, Plasma

Diagnosis of Epstein-Barr virus (EBV)-associated infectious mononucleosis in individuals with equivocal or discordant EBV serologic marker test results Diagnosis of post-transplant lymphoproliferative disorders (PTLD), especially in...

SCN5A - Overview: Brugada Syndrome, SCN5A Full Gene Analysis, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of Brugada syndrome Establishing a diagnosis of Brugada syndrome

PNEFS - Overview: Neuroimmunology Antibody Follow-up, Serum

Monitoring patients who have previously tested positive for one or more antibodies within the past 5 years in a Mayo Neuroimmunology Laboratory serum evaluation

PTNZ - Overview: PTEN Hamartoma Tumor Syndrome, PTEN Full Gene Analysis, Varies

Evaluating patients with a personal or family history suggestive of PTEN hamartoma tumor syndrome (PHTS) Establishing a diagnosis of PHTS allowing for targeted cancer surveillance based on associated risks Identifying variants within...

KRABZ - Overview: Krabbe Disease, Full Gene Analysis and Large (30 kb) Deletion, Varies

Second-tier test for confirming a diagnosis of Krabbe disease Carrier testing for individuals with a family history of Krabbe disease in the absence of known sequence variants in the family

MPSWB - Overview: Mucopolysaccharidosis, Blood

Supporting the biochemical diagnosis of mucopolysaccharidoses type I, II, III, IV, or VI Quantification of heparan sulfate, dermatan sulfate, and keratan sulfate in whole blood specimens

VLCZ - Overview: Very Long Chain Acyl-CoA Dehydrogenase Deficiency, Full Gene Analysis, Varies

Confirmation of a diagnosis of very long chain acyl-CoA dehydrogenase (VLCAD) deficiency Carrier screening in cases where there is a family history of VLCAD deficiency, but an affected individual is not available for testing or...

WEEP - Overview: Western Equine Encephalitis Antibody, IgG and IgM, Serum

Aiding the diagnosis of Western equine encephalitis using serum specimens

USTEK - Overview: Ustekinumab Quantitation with Antibodies, Serum

Evaluation of loss of response to therapy Quantification of ustekinumab in human serum Trough level quantitation for evaluation of patients treated with ustekinumab Detection of antibodies to ustekinumab in human serum

RISAP - Overview: Risankizumab Quantitation with Antibodies, Serum

Evaluation of patients with limited primary (initial) response to or secondary loss of response to risankizumab

FXS - Overview: Fragile X Syndrome, Molecular Analysis, Varies

Confirming a diagnosis of fragile X syndrome, fragile X tremor/ataxia syndrome, or premature ovarian insufficiency caused by expansions in the FMR1 gene Determining carrier status for individuals with a family history of fragile X...

F822P - Overview: Hemophilia A F8 Gene, Intron 22 Inversion Mutation Analysis, Prenatal

Prenatal testing for hemophilia A when a F8 intron 22 inversion has been identified in a family member

HBAG - Overview: Hepatitis B Virus Surface Antigen, Serum

Diagnosis of acute, recent, or chronic hepatitis B Determination of chronic hepatitis B status This test should not be used as a screening or confirmatory test for blood donor specimens.

ESR1T - Overview: ESR1 Mutation Analysis, Next-Generation Sequencing, Tumor

Assisting in the clinical management of patients with metastatic breast cancer by identifying tumors with evolving resistance to endocrine therapy Stratifying prognosis of metastatic breast cancer

DMITO - Overview: Mitochondrial DNA Deletion Heteroplasmy, ddPCR, Varies

Assessing the heteroplasmy level of previously detected large mitochondrial DNA (mtDNA) deletions. Screening family members for previously detected large mtDNA deletions. This test is not recommended for first tier diagnostic testing...

MULT - Overview: Zygosity Testing (Multiple Births), Varies

Determining genetic risk for an individual whose twin or triplet is affected with a genetic disorder for which a specific genetic test is not available (or such testing is uninformative) Assessment of risks prenatally when one fetus of...

HBAGP - Overview: Hepatitis B Virus Surface Antigen Prenatal, Serum

Diagnosis of acute, recent, or chronic hepatitis B Determination of chronic hepatitis B status Screening pregnant women for evidence of chronic hepatitis B (or hepatitis B carrier state) to identify neonates who are at high risk of...

PC2TC - Overview: Purkinje Cell Cytoplasmic Antibody Type 2 (PCA-2) Titer, Spinal Fluid

Evaluating patients who present with a subacute neurological disorder of undetermined etiology and have risk factors for lung cancer Reporting an end titer result from spinal fluid specimens

PC2TS - Overview: Purkinje Cell Cytoplasmic Antibody Type 2 (PCA-2) Titer, Serum

Evaluating patients who present with a subacute neurological disorder of undetermined etiology and have risk factors for lung cancer Reporting an end titer result from serum specimens

VZPG - Overview: Varicella-Zoster Antibody, IgG, Serum

Determination of immune status of individuals to the varicella-zoster virus (VZV) Documentation of previous infection with VZV in an individual without a previous record of immunization to VZV

SMAS - Overview: Smooth Muscle Antibody Screen, Serum

Evaluation of patients with hepatitis of unknown origin associated with hypergammaglobulinemia and/or abnormal liver enzymes

FMBNY - Overview: Fetomaternal Bleed, New York, Blood

Determining the volume of fetal-to-maternal hemorrhage for the purposes of recommending an increased dose of the Rh immune globulin This test is used only for specimens collected in New York state.

PCTTC - Overview: Purkinje Cell Cytoplasmic Antibody, Type Tr (PCA-Tr) Titer, Spinal Fluid

Serological testing for Purkinje cell cytoplasmic antibody-Tr for patients with acquired cerebellar ataxia of undetermined etiology, particularly if the patient has a history of Hodgkin lymphoma Reporting an end titer result from spinal...

FMB - Overview: Fetomaternal Bleed, Flow Cytometry, Blood

Determining the volume of fetal-to-maternal hemorrhage for the purposes of recommending an increased dose of the Rh immune globulin

ADAMS - Overview: ADAMTS13 Activity Assay, Plasma

Assisting with the diagnosis and monitoring of congenital, immune, or acquired thrombotic thrombocytopenic purpura

BUPMX - Overview: Buprenorphine and Norbuprenorphine, Chain of Custody, Random, Urine

Monitoring of compliance of buprenorphine therapy Detection and confirmation of the illicit use of buprenorphine Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the...

OAUS - Overview: Organic Acids Screen, Urine Spot

Diagnosis of inborn errors of metabolism using dried urine specimens

STLP - Overview: St. Louis Encephalitis Antibody, IgG and IgM, Serum

Aiding in the diagnosis of St. Louis encephalitis using serum specimens

CYCL - Overview: Cyclospora Stain, Feces

Identifying Cyclospora cayetanensis as a cause of infectious gastroenteritis

CMVG - Overview: Cytomegalovirus (CMV) Antibodies, IgG, Serum

Determining whether a patient (especially transplant recipients and organ and blood donors) has had a recent infection or previous exposure to cytomegalovirus

EEEP - Overview: Eastern Equine Encephalitis Antibody, IgG and IgM, Serum

Aiding in the diagnosis of Eastern equine encephalitis using serum specimens

HBRP - Overview: Histoplasma capsulatum/Blastomyces species, Molecular Detection, PCR, Varies

Rapid detection of Histoplasma capsulatum and Blastomyces dermatitidis DNA Aiding in the rapid diagnosis of histoplasmosis and blastomycosis

SUBIF - Overview: Immunoglobulin G (IgG) Subtypes Immunofluorescence, Tissue

Determining the subclass of IgG antibody found in renal immunofluorescent panel and determining if the deposits are monoclonal or monotypic

POX - Overview: Fatty Acid Profile, Peroxisomal (C22-C26), Serum

Evaluating patients with possible peroxisomal disorders, single-enzyme defects of peroxisomal metabolism, such as X-linked adrenoleukodystrophy or peroxisomal biogenesis disorders (Zellweger syndrome spectrum) using serum specimens Aiding...

POXP - Overview: Fatty Acid Profile, Peroxisomal (C22-C26), Plasma

Evaluating patients with possible peroxisomal disorders, including peroxisomal biogenesis disorders, X-linked adrenoleukodystrophy, and Refsum disease using plasma specimens Aiding in the assessment of peroxisomal function

COMTQ - Overview: Catechol-O-Methyltransferase (COMT) Genotype, Varies

Prediction of response to nicotine replacement therapy for smoking cessation Investigation of inhibitor dosing for decreasing levodopa metabolism Research use for assessing estrogen metabolism

17PRN - Overview: Pregnenolone and 17-Hydroxypregnenolone, Serum

An ancillary test for congenital adrenal hyperplasia (CAH), particularly in situations in which a diagnosis of both 21- and 11-hydroxylase deficiency have been ruled out Confirming a diagnosis of 3-beta-hydroxysteroid dehydrogenase...

FH7GM - Overview: Herpesvirus 7 IgG and IgM Antibody Panel, IFA

Herpesvirus 7 IgG and IgM Antibody Panel, IFA