AATHR - Overview: Thrombophilia Profile, Plasma and Whole Blood

Evaluating patients with thrombosis or hypercoagulability states Detecting a lupus-like anticoagulant; dysfibrinogenemia; disseminated intravascular coagulation/intravascular coagulation and fibrinolysis Detecting a deficiency of...

PHD2 - Overview: Prolyl Hydroxylase Domain-2 (PHD2/EGLN1) Gene Sequencing, Whole Blood

Assessing PHD2/EGLN1 in the evaluation of an individual with JAK2-negative erythrocytosis associated with lifelong sustained increased red blood cell (RBC) mass, elevated RBC count, hemoglobin, or hematocrit

TFEBF - Overview: Renal Cell Carcinoma, 6p21.1 (TFEB) Rearrangement, FISH, Tissue

Identifying TFEB gene rearrangements in patients with renal cell carcinoma (RCC)

PSYR - Overview: Psychosine, Whole Blood

Aiding in the biochemical diagnosis of Krabbe disease using whole blood specimens Follow-up of individuals affected with Krabbe disease Follow-up testing after an abnormal newborn screening result for Krabbe disease Monitoring of...

HSVC - Overview: Herpes Simplex Virus (HSV), Molecular Detection, PCR, Spinal Fluid

Aiding in the rapid diagnosis of herpes simplex virus (HSV)-1 and HSV-2 infections of the central nervous system

JAK2P - Overview: JAK2 (9p24.1) Rearrangement, Hematologic Disorders, FISH, Tissue

Providing diagnostic information for hematologic malignancies Aiding in the determination of whether a targeted JAK2 inhibitor could be useful for therapy

ANA2 - Overview: Antinuclear Antibodies (ANA), Serum

Evaluating patients at-risk for antinuclear antibodies-associated systemic autoimmune rheumatic disease particularly systemic lupus erythematosus, Sjogren syndrome, and mixed connective tissue disease

ADAMP - Overview: ADAMTS13 Activity with Reflex Inhibitor Profile, Plasma

Assisting with the diagnosis of immune or acquired thrombotic thrombocytopenic purpura

MCRNA - Overview: Chlamydia trachomatis, Miscellaneous Sites, Nucleic Acid Amplification, Varies

Detecting Chlamydia trachomatis in non-US Food and Drug Administration-approved specimen types This test is not intended for use in medico-legal applications. This test is not useful for the detection of Chlamydia pneumoniae or other...

NMHR - Overview: N-Methylhistamine, Random, Urine

Screening for and monitoring of mastocytosis and disorders of systemic mast-cell activation, such as anaphylaxis and other forms of severe systemic allergic reactions using random urine specimens Monitoring therapeutic progress in...

MPRP - Overview: Mycoplasma (Mycoplasmoides) pneumoniae with Macrolide Resistance Reflex, Molecular Detection, PCR, Varies

Diagnosing infections due to Mycoplasma (Mycoplasmoides) pneumoniae Assessing macrolide susceptibility

MPU - Overview: Monoclonal Protein Studies, 24 Hour, Urine

Monitoring patients with monoclonal gammopathies

SMPU - Overview: Monoclonal Protein Screen, 24 Hour, Urine

Monitoring patients with monoclonal gammopathies

QMPTS - Overview: Monoclonal Protein Isotype, Quantitative, Serum

Aiding in the diagnosis and monitoring of monoclonal gammopathies if used in conjunction with free light chain studies This test alone is not considered an adequate screen for monoclonal gammopathies.

TYRBS - Overview: Tyrosinemia Follow Up Panel, Blood Spot

Monitoring of individuals with tyrosinemia type 1 (HT-1) Diagnosis of HT-1 when used in conjunction with testing for urine organic acids, liver function, alpha-fetoprotein, and molecular genetic analysis of the fumarylacetoacetate...

TGOGF - Overview: TGFBR3 (1p22), OGA (10q24) Rearrangement, FISH, Tissue

Supporting the diagnosis of pleomorphic hyalinizing angiectatic tumor, or hemosiderotic fibrolipomatous tumors associated with rearrangement of the OGA and/or TGFBR3 gene when used in conjunction with an anatomic pathology consultation

CORT - Overview: Cortisol, Serum

Discrimination between primary and secondary adrenal insufficiency Differential diagnosis of Cushing syndrome This test is not recommended for evaluating response to metyrapone.

COCOU - Overview: Cortisol/Cortisone, Free, 24 Hour, Urine

Screening test for Cushing syndrome (hypercortisolism) Assisting in diagnosing acquired or inherited abnormalities of 11-beta-hydroxy steroid dehydrogenase (cortisol to cortisone ratio) Diagnosis of pseudo-hyperaldosteronism due to...

CDIF - Overview: Clostridioides difficile Culture, Varies

Providing an isolate suitable for antimicrobial susceptibility testing

CHIKC - Overview: Chikungunya Virus, PCR, Molecular Detection, Spinal Fluid

Qualitative detection of chikungunya virus in cerebrospinal fluid after early symptom onset (ideally <7 days) This test is not recommended for screening healthy patients.

CHIKS - Overview: Chikungunya Virus, PCR, Molecular Detection, Serum

Qualitative detection of chikungunya virus in serum after early symptom onset (ideally <7 days) This test is not recommended for screening healthy patients.

TLCU - Overview: Immunoglobulin Total Light Chains, Urine

Monitoring patients whose urine demonstrates large M-spikes Confirming the quantitation of specimens that show M-spikes by electrophoresis Detecting urine monoclonal proteins and identification of specimens that need urine protein...

MMPGM - Overview: Mumps Virus Antibody, IgM and IgG, Serum

Diagnosis of mumps virus infection Determination of postimmunization immune response of individuals to the mumps vaccine Documentation of previous infection with mumps virus in an individual with no previous record of immunization to...

HIF2A - Overview: Hypoxia-Inducible Factor Alpha (EPAS1/HIF2A) Gene, Exons 9 and 12 Sequencing, Whole Blood

Assessing HIF2A/EPAS1 in the evaluation of an individual with JAK2-negative erythrocytosis associated with lifelong sustained increased red blood cell (RBC) mass, elevated RBC count, hemoglobin, or hematocrit

DDITF - Overview: Myxoid/Round Cell Liposarcoma, 12q13 (DDIT3 or CHOP) Rearrangement, FISH, Tissue

Aiding in the diagnosis of myxoid/round cell liposarcoma by detecting a neoplastic clone associated with gene rearrangement involving the DDIT3 (CHOP) gene region at 12q13

IMTF - Overview: Inflammatory Myofibroblastic Tumors (IMT), 2p23 (ALK) Rearrangement, FISH, Tissue

Supporting the diagnosis of inflammatory myofibroblastic tumors when used conjunction with an anatomic pathology consultation

AD2AR - Overview: PrecivityAD2, Reflex to Apolipoprotein E, Plasma

Assisting in the evaluation of adult patients, aged 55 years and older, with signs or symptoms of mild cognitive impairment or dementia who are being assessed for Alzheimer disease and other causes of cognitive decline Determining APOE E4...

TTRZ - Overview: TTR Gene, Full Gene Analysis, Varies

Establishing a molecular diagnosis for patients with amyloidosis Identifying variants within TTR known to be associated with amyloidosis, allowing for predictive testing of at-risk family members

LSD6W - Overview: Lysosomal Storage Disorders, Six-Enzyme Panel, Leukocytes

Diagnosis of the lysosomal storage disorders: Fabry (in male patients), Gaucher, Krabbe, mucopolysaccharidosis I (MPS I), acid sphingomyelinase deficiency (Niemann-Pick types A and B), and Pompe (glycogen storage disorder type II) This...

LSDGP - Overview: Lysosomal Storage Disease Gene Panel, Varies

Follow up for abnormal biochemical results and confirmation of suspected lysosomal storage disease (LSD) Establishing a molecular diagnosis for patients with LSD Identifying variants within genes known to be associated with LSD, allowing...

GNMY9 - Overview: MYH9-Related Disorders, MYH9 Gene, Next-Generation Sequencing, Varies

Evaluating MYH9-related disorders, including May-Hegglin disorder/anomaly and Sebastian syndrome, in patients with a personal or family history suggestive of an MYH9-related disorder Diagnosing MYH9-related disorders, including May-Hegglin...

CDSP - Overview: Celiac Disease Serology Cascade, Serum

Evaluating patients suspected of having celiac disease, including patients with compatible symptoms, patients with atypical symptoms, and individuals at increased risk (family history, previous diagnosis with associated disease, positivity...

PKC - Overview: Pyruvate Kinase Enzyme Activity, Blood

Evaluation of nonspherocytic hemolytic anemia as a part of a profile Evaluation of neonatal anemia or jaundice Evaluation of unexplained noninfectious hepatic failure Evaluation of unexplained iron overload Evaluation of unusually...

PIT1 - Overview: PIT-1 Immunostain, Technical Component Only

Classification of pituitary adenomas

PARVG - Overview: Parvovirus B19 Antibodies, IgG, Serum

Serologic detection of recent or past parvovirus B19 infection using IgG antibodies This test is not useful as a screening procedure for the general population.

PARVM - Overview: Parvovirus B19 Antibody, IgM, Serum

Serologic detection of recent or past parvovirus B19 infection using IgM antibodies This test is not useful as a screening procedure for the general population.

TTIGS - Overview: Tetanus Toxoid IgG Antibody, Serum

Assessing antibody response to the tetanus toxoid vaccine, which should be performed at least 3 weeks after immunization Aiding in the evaluation of immunodeficiency This test should not be used to diagnose tetanus infection.

WNGS - Overview: West Nile Virus Antibody, IgG, Serum

Detection of IgG antibodies in West Nile virus infections

ZONI - Overview: Zonisamide, Serum

Monitoring zonisamide therapy; recommended for all patients to ensure appropriate dosing Assessing medication compliance

EM - Overview: Electron Microscopy, Varies

Providing information to aid in the diagnosis of medical disorders such as storage diseases, CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy), and primary ciliary dyskinesia

RPRT2 - Overview: Rapid Plasma Reagin Titer, Serum

Determining the current disease status Monitoring response to therapy for syphilis This test cannot be used for testing spinal fluid specimens.

GAL2 - Overview: Probability of Hepatocellular Carcinoma, Serum

Calculation of the risk for patients with chronic liver disease to develop hepatocellular carcinoma

12PU1 - Overview: Protein, Total, 12 Hour, Urine

Evaluation of renal disease Screening for monoclonal gammopathy Screening for postural (orthostatic) proteinuria In select clinical situations, collection of a 12-hour specimen may allow more rapid detection of proteinuria states (eg,...

TRIG1 - Overview: Triglycerides, Serum

Managing atherosclerotic cardiovascular disease risk

TTSC - Overview: Thrombin Time (Bovine), Plasma

Detecting or excluding the presence of heparin or heparin-like anticoagulants (which act by enhancing antithrombin's inhibition of thrombin and other procoagulant enzymes) when used in conjunction with the reptilase time (RT) in evaluating...

SMAT - Overview: Smooth Muscle Antibody Titer, Serum

Antibody titer testing as a part of the evaluation of patients with hepatitis of unknown origin associated with hypergammaglobulinemia and/or abnormal liver enzymes

HEVG - Overview: Hepatitis E Virus IgG Antibody, Serum

Diagnosis of past exposure to hepatitis E virus

2DIS - Overview: Human Leukocyte Antigens (HLA)-DR-DQ Disease Association Typing Low Resolution, Blood

Determining class II human leukocyte antigens (HLA) to identify potential disease associations or markers for drug hypersensitivity

EHRCP - Overview: Ehrlichia Antibody Panel, Serum

An adjunct in the diagnosis of infection with Anaplasma phagocytophilum or Ehrlichia chaffeensis Seroepidemiological surveys of the prevalence of the infection in certain populations

KRTAE - Overview: Keratin (AE1/AE3) Immunostain, Technical Component Only

Identification of cells expressing a broad spectrum of cytokeratins (low and high molecular weight keratins)