Test Catalog

Test Id : SUDC

Sudden Cardiac Death Pathology Consultation

Useful For
Suggests clinical disorders or settings where the test may be helpful

Identifying specific causes contributing to sudden cardiac death

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

An interpretation will be provided by Mayo staff pathologists within a formal pathology report that is sent to the referring Medical Examiner.

 

Appropriate stains and other ancillary testing may be performed and charged separately.

Method Name
A short description of the method used to perform the test

Pathology Consultation

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

Sudden Cardiac Death Path Consult

Aliases
Lists additional common names for a test, as an aid in searching

Cardiovascular autopsy

CV autopsy

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

An interpretation will be provided by Mayo staff pathologists within a formal pathology report that is sent to the referring Medical Examiner.

 

Appropriate stains and other ancillary testing may be performed and charged separately.

Specimen Type
Describes the specimen type validated for testing

SUDC Study Specimen

Ordering Guidance

This test is only orderable for the Sudden Cardiac Death Pathology Evaluation study.

Necessary Information

1. Patient date of birth and date of death are required. All specimens must be labeled with specimen type.

2. The referring pathologist's or medical examiner's name and phone number are required.

3. All specimens, patient history, and requests should be clearly labeled with correct patient identifiers.

Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Specimen Type: Heart

Supplies:

Pathology Packaging Kit (T554)

Refrigerate/Ambient Shipping Box, 5 lb (T329)

Specimen Volume: Entire specimen

Collection Instructions:

1. Fix entire specimen in formalin for a minimum of 24 hours.

2. Following fixation, lightly wrap specimen in formalin-soaked paper towel, place in a leak-proof sealable bag with a small amount of formalin, seal, and ship ambient in a sturdy shipping container.

Additional Information: Paraffin block may be accepted.

 

Specimen Type: Blood

Container/Tube: Lavender top (EDTA)

Specimen Volume: 10 mL

Specimen Minimum Volume
Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

See Specimen Required

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

No specimen should be rejected.

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
SUDC Study Specimen Ambient (preferred)
Frozen
Refrigerated

Useful For
Suggests clinical disorders or settings where the test may be helpful

Identifying specific causes contributing to sudden cardiac death

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

An interpretation will be provided by Mayo staff pathologists within a formal pathology report that is sent to the referring Medical Examiner.

 

Appropriate stains and other ancillary testing may be performed and charged separately.

Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Sudden, unexpected death in individuals less than 40 years old with a strong probability of cardiac disease (including cases of obvious cardiomyopathy, with likely genetic underpinning). This evaluation is offered to provide the careful dissection and diagnostic experience that may be needed for subtle or overt cases of cardiovascular disease.

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

The laboratory will provide a pathology consultation.

Interpretation
Provides information to assist in interpretation of the test results

This request will be processed as a consultation. Appropriate stains and ancillary testing will be performed and an interpretation provided.

Cautions
Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Clinical Reference
Recommendations for in-depth reading of a clinical nature

1. Baudhuin LM, Leduc C, Train LJ, et al: Technical Advances for the Clinical Genomic Evaluation of Sudden Cardiac Death: Verification of Next-Generation Sequencing Panels for Hereditary Cardiovascular Conditions Using Formalin-Fixed Paraffin-Embedded Tissues and Dried Blood Spots. Circ Cardiovasc Genet. 2017 Dec;10(6). doi: 10.1161/CIRCGENETICS.117.001844

2. Ackerman JP, Bartos DC, Kapplinger JD, et al: The Promise and Peril of Precision Medicine: Phenotyping Still Matters Most. Mayo Clin Proc. 2016 Oct 8. pii: S0025-6196(16)30463-3. doi: 10.1016/j.mayocp.2016.08.008

Method Description
Describes how the test is performed and provides a method-specific reference

All requests will be processed as a consultation case. Ancillary studies will be performed only if deemed to be diagnostically indicated.

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Friday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

2 to 4 weeks

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

Rochester

Fees
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their Regional Manager. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

Not Applicable

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.

88037

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports