MCCRC - Overview: MayoComplete Colorectal Cancer Panel, Next-Generation Sequencing, Tumor

Primarily for determining patient response to various targeted therapies or immunotherapy Predicting prognosis from microsatellite instability status

EDMDP - Overview: Inherited Emery-Dreifuss Gene Panel, Varies

Establishing a molecular diagnosis for patients with Emery-Dreifuss muscular dystrophy Identifying variants within genes known to be associated with Emery-Dreifuss muscular dystrophy, allowing for predictive testing of at-risk family...

EGFRW - Overview: EGFR Targeted Mutation Analysis with ALK Reflex, Tumor

Identifying non-small cell lung cancers that may benefit from treatment with epidermal growth factor receptor -targeted therapies or anaplastic lymphoma kinase inhibitors

HYPTG - Overview: Hypertriglyceridemia Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of hereditary forms of primary hypertriglyceridemia and related conditions.

BALFP - Overview: Pediatric B-Lymphoblastic Leukemia/Lymphoma Panel, FISH, Varies

Detecting, at diagnosis, recurrent common chromosome abnormalities associated with B-cell acute lymphoblastic leukemia/lymphoma (B-ALL/LBL) and BCR::ABL1-like B-ALL in pediatric/young adult patients using a laboratory-designated probe set...

ASNA - Overview: Arsenic, Nails

Detection of nonacute arsenic exposure in nail specimens

CRSBF - Overview: Crystal Identification, Body Fluid

Identifying the presence and type of crystals in body fluid

C1Q - Overview: Complement C1q, Serum

Assessment of an undetectable total complement level Diagnosing congenital C1 (first component of complement) deficiency Diagnosing acquired deficiency of C1 inhibitor

CSU - Overview: Chyluria Screen, Random, Urine

Aiding in the diagnosis of chyluria (galacturia)

GLUR1 - Overview: Glucose, Random, Urine

Limited usefulness for routine screening or management of diabetes mellitus

FIBDD - Overview: PROMETHEUS IBD sgi Diagnostic

PROMETHEUS IBD sgi Diagnostic

FLUPV - Overview: Lupus Anticoagulant Evaluation with Reflex

Lupus Anticoagulant Evaluation with Reflex

THSIF - Overview: Thrombospondin Type 1 Domain Containing 7A (THSD7A), Immunofluorescence

Diagnosis of thrombospondin type 1 domain-containing 7A (THSD7A)-associated membranous nephropathy

BUN - Overview: Blood Urea Nitrogen (BUN), Serum

Screening test for evaluation of kidney function

BRAZX - Overview: Brazil Nut Component, IgE, Serum

Evaluation of patients with suspected Brazil nut allergy to component Ber e 1

HBCSN - Overview: Hepatitis B Virus Core Total Antibodies Screen, Serum

Diagnosis of recent or past hepatitis B Determination of occult hepatitis B in otherwise healthy hepatitis B virus carriers with negative test results for hepatitis B surface (HBs) antigen, anti-HBs, anti-hepatitis B core IgM, hepatitis...

NMOFS - Overview: Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay, Serum

Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD) Diagnosis of autoimmune AQP4 channelopathy Diagnosis of neuromyelitis optica (NMO) Distinguishing NMOSD from multiple sclerosis early in the course of disease

ACLIP - Overview: Phospholipid (Cardiolipin) Antibodies, IgA, Serum

May be of diagnostic significance for patients at risk for antiphospholipid syndrome or systemic lupus erythematosus who test negative for criterial antiphospholipid antibodies

PLAFL - Overview: Platelet Surface Glycoprotein by Flow Cytometry, Blood

Identification of markedly decreased CD41 (GPIIb) and CD61 (GPIIIa) expression levels, which are diagnostic for Glanzmann thrombasthenia Identification of markedly decreased CD42a (GPIX) and CD42b (GPIb-alpha) expression levels, which are...

FQPPS - Overview: Porphyrins, Feces

Evaluation of patients who present with signs or symptoms suggestive of porphyria cutanea tarda, hereditary coproporphyria, variegate porphyria, congenital erythropoietic porphyria, erythropoietic protoporphyria, or X-linked dominant...

MSMRT - Overview: Mayo Algorithmic Approach for Stratification of Myeloma and Risk-Adapted Therapy Report, Bone Marrow

Risk stratification of patients with treated multiple myeloma, which can assist in determining treatment and management decisions Risk stratification of patients with newly diagnosed multiple myeloma

TTRX - Overview: Amyloidosis, Transthyretin-Associated Familial, Reflex, Blood

Diagnosis of adult individuals suspected of having transthyretin-associated familial amyloidosis

TERTD - Overview: TERT Promoter Mutation Analysis, Droplet Digital PCR, Tumor

Identifying specific mutations within the TERT promoter that assist in tumor diagnosis/classification

RPR8 - Overview: Respiratory Profile, Region 8, Central Midwest (IA, IL, MO), Serum

Assessing sensitization to various inhalant allergens commonly found in the Central Midwest region including Iowa, Illinois, and Missouri Defining the allergen responsible for eliciting signs and symptoms Identifying...

RPR12 - Overview: Respiratory Profile, Region 12, Arid Southwest (Southern AZ Desert, Southern CA Desert), Serum

Assessing sensitization to various inhalant allergens commonly found in the arid Southwest region, including the southern Arizona desert and the southern California desert Defining the allergen responsible for eliciting signs and...

XHIM - Overview: X-Linked Hyper IgM Syndrome, Blood

Screening for X-linked hyper-IgM (XL-HIGM) or CD40L deficiency, primarily in male patients younger than 10 years Ascertaining XL-HIGM carrier status in women of child-bearing age (younger than 45 years)

PT217 - Overview: Phospho-Tau 217, Plasma

Evaluation of individuals, aged 50 years and older, presenting with cognitive impairment who are being assessed for Alzheimer disease and other causes of cognitive decline This test is not intended as a screening test for Alzheimer...

AMLFP - Overview: Pediatric Acute Myeloid Leukemia Panel, FISH, Varies

Detecting, at diagnosis, recurrent common chromosome abnormalities associated with acute myeloid leukemia (AML) in patients 30 years and younger using a laboratory-designated probe set algorithm As an adjunct to conventional chromosome...

PCDES - Overview: Pediatric Autoimmune Encephalopathy/CNS Disorder Evaluation, Serum

Evaluating children with autoimmune central nervous system disorders using serum specimens

BABPB - Overview: Babesia species, Molecular Detection, PCR, Blood

Initial screening or confirmatory testing for suspected babesiosis during the acute febrile stage of infection in patients from endemic areas, especially when Giemsa-stained peripheral blood smears do not reveal any organisms, or the...

CMAT - Overview: Chromosomal Microarray, Tumor, Fresh or Frozen

Genomic characterization of tumor for copy number imbalances and loss of heterozygosity Assisting in the diagnosis and classification of malignant neoplasms, including hematolymphoid malignancies Evaluating the prognosis for patients with...

CDIF - Overview: Clostridioides difficile Culture, Varies

Providing an isolate suitable for antimicrobial susceptibility testing

MMPGM - Overview: Mumps Virus Antibody, IgM and IgG, Serum

Diagnosis of mumps virus infection Determination of postimmunization immune response of individuals to the mumps vaccine Documentation of previous infection with mumps virus in an individual with no previous record of immunization to...

NSESF - Overview: Neuron-Specific Enolase (NSE), Spinal Fluid

An auxiliary test in the diagnosis of Creutzfeldt-Jakob disease An auxiliary test in the diagnosis of small cell lung carcinoma metastasis to central nervous system or leptomeninges

ROPAN - Overview: Ro52 and Ro60 Antibodies, IgG, Serum

Evaluating patients at risk for connective tissue disease with or without interstitial lung disease Differentiation of antibodies to Ro52 and Ro60 in patients known to be positive for anti-SS-A (Ro) antibodies

DSM5X - Overview: Drugs of Abuse Screen 5, Chain of Custody, Meconium

Identifying amphetamines (and methamphetamines), opiates, and phencyclidine, as well as metabolites of cocaine and marijuana in meconium specimens Chain of custody is required whenever the results of testing could be used in a court of...

DSM4X - Overview: Drugs of Abuse Screen 4, Chain of Custody, Meconium

Identifying amphetamines (and methamphetamines) and opiates, as well as metabolites of cocaine and marijuana in meconium specimen Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is...

FFRBS - Overview: Friedreich Ataxia, Frataxin, Quantitative, Blood Spot

Diagnosing individuals with Friedreich ataxia in blood spot specimens Monitoring frataxin levels in patients with Friedreich ataxia This test is not useful for carrier detection.

AFH - Overview: Factor H Autoantibody, Serum

Detection and quantification of antibodies to factor H Monitoring patients with known factor H autoantibodies Aiding in the differential diagnosis of thrombotic microangiopathy and C3 glomerulopathies

LAD1 - Overview: Leukocyte Adhesion Deficiency Type 1, CD11a/CD18 and CD11b/CD18 Complex Immunophenotyping, Blood

Aiding in the diagnosis of leukocyte adhesion deficiency syndrome type 1, primarily in patients younger than 18 years CD11a, CD11b, and CD18 phenotyping

LKM - Overview: Liver/Kidney Microsome Type 1 Antibodies, Serum

Evaluation of patients with liver disease of unknown etiology Evaluation of patients with suspected autoimmune hepatitis

T4 - Overview: T4 (Thyroxine), Total Only, Serum

Monitoring treatment with synthetic hormones (synthetic T3 [triiodothyronine] will cause a low total T4 [thyroxine]) Monitoring treatment of hyperthyroidism with thiouracil and other anti-thyroid drugs Index of thyroid function when the...

SRAU - Overview: Serotonin Release Assay, Unfractionated Heparin, Mass Spectrometry, Serum

Detecting heparin-dependent platelet activating antibodies implicated in the pathogenesis of heparin-induced thrombocytopenia

VMA - Overview: Vanillylmandelic Acid, 24 Hour, Urine

Screening children for catecholamine-secreting tumors using a 24-hour urine collection when requesting testing for vanillylmandelic acid only Supporting a diagnosis of neuroblastoma Monitoring patients with a treated neuroblastoma

BNZU - Overview: Benzodiazepines Confirmation, Random, Urine

Detecting drug use involving benzodiazepines such as alprazolam, chlordiazepoxide, clonazepam, diazepam, midazolam, oxazepam, temazepam, clobazam, flunitrazepam, flurazepam, lorazepam, prazepam, triazolam, and zolpidem

BALLM - Overview: B-Cell Lymphoblastic Leukemia Monitoring, Minimal Residual Disease Detection, Flow Cytometry, Varies

Aids in monitoring a previously confirmed diagnosis of B-cell acute lymphoblastic leukemia

7AC4 - Overview: 7AC4, Bile Acid Synthesis, Serum

Screening for bile acid malabsorption in patients with irritable bowel syndrome with diarrhea

DCORT - Overview: 11-Deoxycortisol, Serum

Diagnostic workup of patients with congenital adrenal hyperplasia Part of metyrapone testing in the workup of suspected secondary or tertiary adrenal insufficiency Part of metyrapone testing in the differential diagnostic workup of...

MATCC - Overview: Maternal Cell Contamination, Molecular Analysis, Varies

Ruling out the presence of maternal cell contamination within a fetal specimen Required for all prenatal testing performed in Mayo Clinic Laboratories' Molecular and Biochemical Genetics laboratories

CSTB - Overview: CSTB Gene, Repeat Expansion Analysis, Varies

Molecular confirmation of clinically suspected CSTB-related progressive myoclonic epilepsy Identifying full penetrance dodecamer repeat expansions within CSTB known to cause CSTB-related progressive myoclonic epilepsy, allowing for...