MLH1 - Overview: MLH1 Immunostain, Technical Component Only

Evaluation of tumor tissue to identify patients at high risk for having hereditary nonpolyposis colorectal cancer, also known as Lynch syndrome Evaluation of tumor tissue to identify patients at risk for having hereditary endometrial...

IDUAW - Overview: Alpha-L-Iduronidase, Leukocytes

Diagnosis of mucopolysaccharidosis I, Hurler, Scheie, and Hurler-Scheie syndromes in leukocytes This test is not useful for determining carrier status.

TCP - Overview: T-Cell Subsets, Naive, Memory, and Activated, Blood

Determining the presence of naive, memory, and activated T cells in various clinical contexts including autoimmune diseases, immunodeficiency states, T-cell recovery post-hematopoietic stem cell transplant, DiGeorge syndrome, and as a...

BART - Overview: Bartonella Antibody Panel, IgG and IgM, Serum

Diagnosis of Bartonella infection, especially in the context of a cat scratch

HIBAG - Overview: Histoplasma and Blastomyces Antigen, Enzyme Immunoassay, Serum

Diagnosing Histoplasma capsulatum or Blastomyces dermatitidis infection, without differentiation between the organisms, using serum specimens Monitor antigen levels following initiation of antifungal treatment

LH - Overview: Luteinizing Hormone (LH), Serum

An adjunct in the evaluation of menstrual irregularities Evaluating patients with suspected hypogonadism Predicting ovulation Evaluating infertility Diagnosing pituitary disorders

CHAGS - Overview: Trypanosoma cruzi Total Antibody, Enzyme-Linked Immunosorbent Assay, Serum

Diagnosis of chronic Trypanosoma cruzi infection (Chagas disease)

NGCLN - Overview: MayoComplete Chronic Lymphoid Neoplasms, Next-Generation Sequencing, Varies

Aiding in establishing diagnosis, refining prognosis, and potentially identifying targeted therapies for the optimal management of patients with chronic or low-grade B-cell lymphoid neoplasms

MCKCP - Overview: MayoComplete Kidney Cancer Panel, Next-Generation Sequencing, Tumor

Identifying specific mutations to assist in tumor diagnosis/classification Assisting in the clinical management of patients with renal cell carcinoma Assessment of microsatellite instability for immunotherapy decisions

IEHCG - Overview: Interference Evaluation Heterophile, Beta-Human Chorionic Gonadotropin, Serum

Evaluating suspected interference from heterophile antibodies causing a falsely elevated human chorionic gonadotropin result This test is not to be used for pregnancy testing.

NGBCL - Overview: MayoComplete B-Cell Lymphoma, Next-Generation Sequencing, Varies

Aiding in establishing diagnosis, refining prognosis, and potentially identifying targeted therapies for the optimal management of patients with B-cell lymphomas

MPS1Z - Overview: Hurler Syndrome, Full Gene Analysis, Varies

Identifying variants within the IDUA gene Confirmation of a diagnosis of mucopolysaccharidosis type I (MPS-I) Carrier testing when there is a family history of MPS- I, but disease-causing variants have not been previously identified

MSFNG - Overview: Fibronectin Glomerulopathy Confirmation, Mass Spectrometry

Aiding in the diagnosis of fibronectin glomerulopathy

ANA2 - Overview: Antinuclear Antibodies (ANA), Serum

Evaluating patients at-risk for antinuclear antibodies-associated systemic autoimmune rheumatic disease particularly systemic lupus erythematosus, Sjogren syndrome, and mixed connective tissue disease

DTABS - Overview: Diphtheria/Tetanus Antibody Panel, Serum

Assessing antibody response to tetanus and diphtheria toxoid vaccines, which should be performed at least 3 weeks after immunization Aiding in the evaluation of immunodeficiency This test should not be used to diagnose tetanus infection

C341Q - Overview: Complement C3 and C4 with Anti-C1q Antibodies, Serum

Evaluating patients with suspected anti-C1q vasculitis Predicting renal involvement in patients with systemic lupus erythematosus

ADIC - Overview: Disseminated Intravascular Coagulation/Intravascular Coagulation and Fibrinolysis (DIC/ICF) Profile, Plasma

Establishing laboratory evidence of disseminated intravascular coagulation

AATHR - Overview: Thrombophilia Profile, Plasma and Whole Blood

Evaluating patients with thrombosis or hypercoagulability states Detecting a lupus-like anticoagulant; dysfibrinogenemia; disseminated intravascular coagulation/intravascular coagulation and fibrinolysis Detecting a deficiency of...

AFXN - Overview: Friedreich Ataxia, Repeat Expansion Analysis, Varies

Molecular confirmation of clinically suspected Friedreich ataxia

BRACH - Overview: Brachyury Immunostain, Technical Component Only

Aiding in the identification of chordomas

BCOR - Overview: BCOR Immunostain, Technical Component Only

Aiding in the distinction of a subset of primitive round cell sarcomas with BCOR rearrangements from other Ewing/Ewing-like sarcomas

BCATN - Overview: Beta-Catenin Immunostain, Technical Component Only

Identification of aberrant nuclear staining pattern observed in some tumors

AATRP - Overview: Alpha-1-Antitrypsin Immunostain, Technical Component Only

Identification of abnormal accumulation of alpha-1-antitrypsin

CD303 - Overview: CD303 (BDCA-2) Immunostain, Technical Component Only

Diagnosis of blastic plasmacytoid dendritic cell neoplasm

CD200 - Overview: CD200 (OX2) Immunostain, Technical Component Only

Identifying the presence of CD200 (OX2) protein within chronic lymphocytic leukemia, small lymphocytic lymphoma, hairy cell leukemia, and primary mediastinal large B-cell lymphoma

IDH2 - Overview: IHD2, R172K Mutation, Immunostain, Technical Component Only

Identification of IDH2 R172K mutant protein in angioimmunoblastic T-cell lymphoma or acute myeloid leukemia

HEPAT - Overview: Hepatocyte Immunostain, Technical Component Only

Distinguishing hepatocellular carcinoma from other types of cancer

ISLET - Overview: Islet 1 Immunostain, Technical Component Only

Identification of endocrine tumors

CD23 - Overview: CD23 Immunostain, Technical Component Only

Identification of follicular dendritic cells Classification of low-grade B-cell lymphomas

CD5 - Overview: CD5 Immunostain, Technical Component Only

Marker of T-cell lineage Phenotyping B-cell lymphomas

CD10 - Overview: CD10 Immunostain, Technical Component Only

Phenotyping leukemias and lymphomas

CLDN4 - Overview: Claudin-4 Immunostain, Technical Component Only

Distinguishing carcinoma from mesothelioma and sarcoma

GLYCF - Overview: Glycophorin A (CD235a) Immunostain, Technical Component Only

Aiding in the identification of erythroid precursors in bone marrow

GRH - Overview: Growth Hormone Immunostain, Technical Component Only

Aids in the identification of growth hormone adenomas

HBZ - Overview: Human T-cell Lymphotropic Virus Type 1 (HTLV-1) bZIP Factor (HBZ), In Situ Hybridization, Technical Component Only

Diagnosing adult T-cell leukemia/lymphoma

MT - Overview: Metallothionein Immunostain, Technical Component Only

Supporting the diagnosis of Wilson disease

PLAIF - Overview: Phospholipase A2 Receptor (PLA2R), Renal Biopsy

Distinguishing primary membranous nephropathy from secondary membranous nephropathy

PAX5 - Overview: PAX-5 Immunostain, Technical Component Only

Classification of lymphomas

P40 - Overview: p40 Immunostain, Technical Component Only

Diagnosis and classification of carcinomas and lymphomas

P57I - Overview: p57 (KIP2/CDKN1C) Immunostain, Technical Component Only

Aids in the identification of cytotrophoblasts, intermediate trophoblasts, and villous stromal cells

PLAP - Overview: Placental Alkaline Phosphatase (PLAP) Immunostain, Technical Component Only

Aids in the identification of germ cell tumors

EBNA2 - Overview: Epstein Barr Nuclear Antigen 2 (EBNA2) Immunostain, Technical Component Only

Identification of Epstein Barr virus infection in normal, inflammatory, and neoplastic tissues

CALD - Overview: Caldesmon Immunostain, Technical Component Only

As a marker of smooth muscle differentiation

FLI1 - Overview: FLI-1 Immunostain, Technical Component Only

Aiding in phenotyping endothelial-derived tumors, Ewing sarcoma, Merkel cell carcinoma, lung adenocarcinoma, melanoma, and erythroleukemia

KRT5 - Overview: Keratin 5 (KRT5) Immunostain, Technical Component Only

Differentiation of mesothelioma and squamous cell carcinoma versus adenocarcinoma

LYSOZ - Overview: Lysozyme Immunostain, Technical Component Only

Aiding in confirmation of monocytic and histiocytic differentiation

KRT34 - Overview: Keratin (34BE12) Immunostain, Technical Component Only

Identification of cells expressing high-molecular-weight cytokeratin

MALI - Overview: MAL Immunostain, Technical Component Only

Diagnosis of primary mediastinal large B-cell lymphoma

MYC - Overview: MYC Immunostain, Technical Component Only

Assessment of MYC expression

MYOGL - Overview: Myoglobin Immunostain, Technical Component Only

Marker of skeletal and cardiac muscle