PIT1 - Overview: PIT-1 Immunostain, Technical Component Only
Classification of pituitary adenomas
PU1 - Overview: PU.1 Immunostain, Technical Component Only
Classification of lymphomas
TLE1 - Overview: TLE-1 Immunostain, Technical Component Only
Aids in the identification of synovial sarcoma
GLUT - Overview: GLUT-1 Immunostain, Technical Component Only
Identification of erythrocytes in various normal and neoplastic tissues
FLI1 - Overview: FLI-1 Immunostain, Technical Component Only
Aiding in phenotyping endothelial-derived tumors, Ewing sarcoma, Merkel cell carcinoma, lung adenocarcinoma, melanoma, and erythroleukemia
ISLET - Overview: Islet 1 Immunostain, Technical Component Only
Identification of endocrine tumors
A124 - Overview: Alpha-1-Microglobulin, 24 Hour, Urine
Assessment of renal tubular injury or dysfunction using 24-hour urine collections Screening for tubular abnormalities Detecting chronic asymptomatic renal tubular dysfunction(2)
ANNEX - Overview: Annexin-1 Immunostain, Technical Component Only
Classification of leukemias
ARGIN - Overview: Arginase-1 Immunostain, Technical Component Only
Identification and differentiation of hepatocellular carcinoma
A1AFS - Overview: Alpha-1-Antitrypsin Clearance, Feces and Serum
Diagnosing protein-losing enteropathies
BOB1 - Overview: BOB-1 Immunostain, Technical Component Only
Classification of lymphomas
NEUD1 - Overview: Neuronal Differentiation 1 (NeuroD1), Technical Component only
Subclassification of small cell lung carcinoma
SF1 - Overview: SF-1 Immunostain, Technical Component Only
Classification of pituitary adenomas
CLAUD - Overview: Claudin-1 Immunostain, Technical Component Only
Identification of a number of different soft tissue and epithelial neoplasms
DOG1 - Overview: DOG-1 Immunostain, Technical Component Only
Identification of gastrointestinal stromal tumors
Diagnosing adult T-cell leukemia/lymphoma
LKM - Overview: Liver/Kidney Microsome Type 1 Antibodies, Serum
Evaluation of patients with liver disease of unknown etiology Evaluation of patients with suspected autoimmune hepatitis
MUM1 - Overview: MUM-1/IRF4 Immunostain, Technical Component Only
Aids in the identification of hematolymphoid neoplasms and melanomas
CD279 - Overview: CD279 (PD-1) Immunostain, Technical Component Only
Identification of follicular T helper cells Phenotyping of angioimmunoblastic T-cell lymphoma
GALTP - Overview: Galactose-1-Phosphate Uridyltransferase Biochemical Phenotyping, Erythrocytes
Determining the biochemical phenotype for galactosemia when enzymatic and molecular results are incongruent
Distinguishing between hepatocellular carcinoma and chronic liver disease Monitoring individuals with hepatic cirrhosis from any etiology for progression to hepatocellular carcinoma Surveillance for development of hepatocellular...
WT1I - Overview: Wilms Tumor (WT-1) Immunostain, Technical Component Only
Aiding in the identification of Wilms tumor
KI67 - Overview: Ki-67 (MIB-1) Immunostain, Technical Component Only
A marker of proliferation in neoplasms
KIPM - Overview: Ki-67(MIB-1), Pulmonary, Quantitative Immunohistochemistry, Manual
Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with carcinoid or atypical carcinoid of the lung including metastases, using a manual method
KI67P - Overview: Ki-67(MIB-1), Pulmonary, Quantitative Immunohistochemistry, Automated
Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with carcinoid or atypical carcinoid of the lung including metastases
KI67B - Overview: Ki-67(MIB-1), Breast, Quantitative Immunohistochemistry, Automated
Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with breast carcinoma
HBME - Overview: Mesothelial Cell (HBME-1) Immunostain, Technical Component Only
Classification of thyroid carcinomas
THSD7 - Overview: Thrombospondin Type-1 Domain-Containing 7A Antibodies, Serum
Distinguishing primary from secondary membranous nephropathy cases with antibodies against THSD7A
MELAN - Overview: Melan A (MART-1) Immunostain, Technical Component Only
Aids in the identification of melanoma
IGFMS - Overview: Insulin-Like Growth Factor-1, Mass Spectrometry, Serum
Evaluation of growth disorders Evaluation of growth hormone deficiency or excess in children and adults Monitoring of recombinant human growth hormone treatment Follow-up of individuals with acromegaly and gigantism
Identification of breast carcinoma including triple negative breast cancer
TTF8G - Overview: Thyroid Transcription Factor (8G7G3/1) Immunostain, Technical Component Only
Identification of thyroid or lung cells as the primary tumor site in carcinomas of unknown origin
MYOD1 - Overview: Myogenic Differentiation Antigen 1 (MYOD1) Immunostain, Technical Component Only
Marker of skeletal muscle differentiation
FFMSS - Overview: Maternal Serum Screening, Integrated, Specimen #1, PAPP-A, NT
Helpful to identify pregnancies at increased risk of having a child with Down Syndrome (DS), open neural tube defects (ONTD) and trisomy 18 (T18). This test is not diagnostic.
FGFRC - Overview: Fibroblast Growth Factor Receptor 1, Immunostain, Technical Component Only
Classification of a subset of lung squamous cell carcinoma
KIBM - Overview: Ki-67(MIB-1), Breast, Semi-Quantitative Immunohistochemistry, Manual
Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with breast carcinoma
INSM1 - Overview: Insulinoma-Associated Protein 1 (INSM1), Immunostain, Technical Component Only
Identification of neuroendocrine tumors
INI1 - Overview: Integrase Interactor 1 (INI1/BAF47) Immunostain, Technical Component Only
Part of a panel of immunostains where loss of staining can be used as a marker of various neoplasms
MUM1B - Overview: MUM-1/IRF4 Immunostain, Bone Marrow, Technical Component Only
Aiding in the identification of hematolymphoid neoplasms and melanomas
DSGAB - Overview: Desmoglein 1 (DSG1) and Desmoglein 3 (DSG3), IgG Antibodies, Serum
Preferred screening test for patients suspected to have an autoimmune blistering disorder of the skin or mucous membranes (pemphigus) Aiding in the diagnosis of pemphigus
GAB1 - Overview: GRB2-Associated Binding Protein 1 (GAB1) Immunostain, Technical Component Only
Identification and differentiation of medulloblastomas
LEF1 - Overview: Lymphoid Enhancer-Binding Factor 1(LEF1) Immunostain, Technical Component Only
Differentiating cancers of B-cell origin
Aids in the diagnosis of epithelioid hemangioendotheliomas
TYRBS - Overview: Tyrosinemia Follow Up Panel, Blood Spot
Monitoring of individuals with tyrosinemia type 1 (HT-1) Diagnosis of HT-1 when used in conjunction with testing for urine organic acids, liver function, alpha-fetoprotein, and molecular genetic analysis of the fumarylacetoacetate...
F8INP - Overview: Hemophilia A F8 Gene, Intron 1 and 22 Inversion Mutation Analysis, Prenatal
Prenatal testing for hemophilia A when a variant has not been identified in the family
GCET - Overview: Germinal Center B-cell Expressed Transcript 1 Immunostain, Technical Component Only
Classification of lymphomas
Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with neuroendocrine tumors of the pancreas or gastrointestinal tract including metastases
Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with neuroendocrine tumors of the pancreas or gastrointestinal tract including metastases
Identification of Epstein Barr virus infection in normal, inflammatory, and neoplastic tissues
KRASW - Overview: KRAS Somatic Mutation Analysis, Peritoneal Fluid
Staging of the pancreatic ductal adenocarcinoma(1)
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Detection of (1→3)-𝝱-D-glucan as a Marker of Invasive Fungal Disease - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the detection of (1→3)-β-D-glucan (BDG) in serum as a biomarker for the presence of invasive fungal infections....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....