ISLET - Overview: Islet 1 Immunostain, Technical Component Only

Identification of endocrine tumors

ANNEX - Overview: Annexin-1 Immunostain, Technical Component Only

Classification of leukemias

ARGIN - Overview: Arginase-1 Immunostain, Technical Component Only

Identification and differentiation of hepatocellular carcinoma

A1AFS - Overview: Alpha-1-Antitrypsin Clearance, Feces and Serum

Diagnosing protein-losing enteropathies

BOB1 - Overview: BOB-1 Immunostain, Technical Component Only

Classification of lymphomas

NEUD1 - Overview: Neuronal Differentiation 1 (NeuroD1), Technical Component only

Subclassification of small cell lung carcinoma

SF1 - Overview: SF-1 Immunostain, Technical Component Only

Classification of pituitary adenomas

CLAUD - Overview: Claudin-1 Immunostain, Technical Component Only

Identification of a number of different soft tissue and epithelial neoplasms

DOG1 - Overview: DOG-1 Immunostain, Technical Component Only

Identification of gastrointestinal stromal tumors

A124 - Overview: Alpha-1-Microglobulin, 24 Hour, Urine

Assessment of renal tubular injury or dysfunction using 24-hour urine collections Screening for tubular abnormalities Detecting chronic asymptomatic renal tubular dysfunction(2)

HBZ - Overview: Human T-cell Lymphotropic Virus Type 1 (HTLV-1) bZIP Factor (HBZ), In Situ Hybridization, Technical Component Only

Diagnosing adult T-cell leukemia/lymphoma

LKM - Overview: Liver/Kidney Microsome Type 1 Antibodies, Serum

Evaluation of patients with liver disease of unknown etiology Evaluation of patients with suspected autoimmune hepatitis

MUM1 - Overview: MUM-1/IRF4 Immunostain, Technical Component Only

Aids in the identification of hematolymphoid neoplasms and melanomas

CD279 - Overview: CD279 (PD-1) Immunostain, Technical Component Only

Identification of follicular T helper cells Phenotyping of angioimmunoblastic T-cell lymphoma

GALTP - Overview: Galactose-1-Phosphate Uridyltransferase Biochemical Phenotyping, Erythrocytes

Determining the biochemical phenotype for galactosemia when enzymatic and molecular results are incongruent

L3AFP - Overview: Alpha-Fetoprotein (AFP) L3% and Total, Hepatocellular Carcinoma Tumor Marker, Serum

Distinguishing between hepatocellular carcinoma and chronic liver disease Monitoring individuals with hepatic cirrhosis from any etiology for progression to hepatocellular carcinoma Surveillance for development of hepatocellular...

WT1I - Overview: Wilms Tumor (WT-1) Immunostain, Technical Component Only

Aiding in the identification of Wilms tumor

KI67 - Overview: Ki-67 (MIB-1) Immunostain, Technical Component Only

A marker of proliferation in neoplasms

KIPM - Overview: Ki-67(MIB-1), Pulmonary, Quantitative Immunohistochemistry, Manual

Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with carcinoid or atypical carcinoid of the lung including metastases, using a manual method

KI67P - Overview: Ki-67(MIB-1), Pulmonary, Quantitative Immunohistochemistry, Automated

Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with carcinoid or atypical carcinoid of the lung including metastases

KI67B - Overview: Ki-67(MIB-1), Breast, Quantitative Immunohistochemistry, Automated

Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with breast carcinoma

HBME - Overview: Mesothelial Cell (HBME-1) Immunostain, Technical Component Only

Classification of thyroid carcinomas

THSD7 - Overview: Thrombospondin Type-1 Domain-Containing 7A Antibodies, Serum

Distinguishing primary from secondary membranous nephropathy cases with antibodies against THSD7A

MELAN - Overview: Melan A (MART-1) Immunostain, Technical Component Only

Aids in the identification of melanoma

CYTH1 - Overview: T-Helper Cell Type 1 Cytokine Panel, Plasma

Assessment of plasma cytokine levels to understand the etiology of autoimmune and proinflammatory conditions when used in conjunction with clinical information and other laboratory testing

IGFMS - Overview: Insulin-Like Growth Factor-1, Mass Spectrometry, Serum

Evaluation of growth disorders Evaluation of growth hormone deficiency or excess in children and adults Monitoring of recombinant human growth hormone treatment Follow-up of individuals with acromegaly and gigantism

TRPS1 - Overview: Trichorhinophalangeal syndrome type 1 (TRPS1) Immunostain, Technical Component Only

Identification of breast carcinoma including triple negative breast cancer

TTF8G - Overview: Thyroid Transcription Factor (8G7G3/1) Immunostain, Technical Component Only

Identification of thyroid or lung cells as the primary tumor site in carcinomas of unknown origin

MYOD1 - Overview: Myogenic Differentiation Antigen 1 (MYOD1) Immunostain, Technical Component Only

Marker of skeletal muscle differentiation

FGFRC - Overview: Fibroblast Growth Factor Receptor 1, Immunostain, Technical Component Only

Classification of a subset of lung squamous cell carcinoma

KIBM - Overview: Ki-67(MIB-1), Breast, Semi-Quantitative Immunohistochemistry, Manual

Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with breast carcinoma

INSM1 - Overview: Insulinoma-Associated Protein 1 (INSM1), Immunostain, Technical Component Only

Identification of neuroendocrine tumors

INI1 - Overview: Integrase Interactor 1 (INI1/BAF47) Immunostain, Technical Component Only

Part of a panel of immunostains where loss of staining can be used as a marker of various neoplasms

MUM1B - Overview: MUM-1/IRF4 Immunostain, Bone Marrow, Technical Component Only

Aiding in the identification of hematolymphoid neoplasms and melanomas

DSGAB - Overview: Desmoglein 1 (DSG1) and Desmoglein 3 (DSG3), IgG Antibodies, Serum

Preferred screening test for patients suspected to have an autoimmune blistering disorder of the skin or mucous membranes (pemphigus) Aiding in the diagnosis of pemphigus

FFMSS - Overview: Maternal Serum Screening, Integrated, Specimen #1, PAPP-A, NT

Helpful to identify pregnancies at increased risk of having a child with Down Syndrome (DS), open neural tube defects (ONTD) and trisomy 18 (T18). This test is not diagnostic.

GAB1 - Overview: GRB2-Associated Binding Protein 1 (GAB1) Immunostain, Technical Component Only

Identification and differentiation of medulloblastomas

LEF1 - Overview: Lymphoid Enhancer-Binding Factor 1(LEF1) Immunostain, Technical Component Only

Differentiating cancers of B-cell origin

CAMTA - Overview: Calmodulin-Binding Transcription Activator 1 (CAMTA1), Immunostain, Technical Component Only

Aids in the diagnosis of epithelioid hemangioendotheliomas

TYRBS - Overview: Tyrosinemia Follow Up Panel, Blood Spot

Monitoring of individuals with tyrosinemia type 1 (HT-1) Diagnosis of HT-1 when used in conjunction with testing for urine organic acids, liver function, alpha-fetoprotein, and molecular genetic analysis of the fumarylacetoacetate...

F8INP - Overview: Hemophilia A F8 Gene, Intron 1 and 22 Inversion Mutation Analysis, Prenatal

Prenatal testing for hemophilia A when a variant has not been identified in the family

GCET - Overview: Germinal Center B-cell Expressed Transcript 1 Immunostain, Technical Component Only

Classification of lymphomas

KINET - Overview: Ki-67(MIB-1), Gastrointestinal/Pancreatic Neuroendocrine Tumors, Quantitative Immunohistochemistry, Automated

Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with neuroendocrine tumors of the pancreas or gastrointestinal tract including metastases

KINM - Overview: Ki-67(MIB-1), Gastrointestinal/Pancreatic Neuroendocrine Tumors, Quantitative Immunohistochemistry, Manual

Determining proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with neuroendocrine tumors of the pancreas or gastrointestinal tract including metastases

LMP1I - Overview: Epstein Barr Virus Latency Membrane Protein 1 Immunostain, Technical Component Only

Identification of Epstein Barr virus infection in normal, inflammatory, and neoplastic tissues

KRASW - Overview: KRAS Somatic Mutation Analysis, Peritoneal Fluid

Staging of the pancreatic ductal adenocarcinoma(1)

SUAC - Overview: Succinylacetone, Blood Spot

Second-tier newborn screen for tyrosinemia type 1 (HT-1) when primary screen showed nonspecific elevations of tyrosine Diagnosing HT-1 when used in conjunction with testing for urine organic acids, liver function, alpha-fetoprotein, and...

SCARA - Overview: Spinocerebellar Ataxia Type 1, 2, 3, 6, or 7, Repeat Expansion Analysis, Varies

Diagnostic or predictive testing when clinical symptoms or a family history are specific to only one type of spinocerebellar ataxia

F8INV - Overview: Hemophilia A F8 Gene, Intron 1 and 22 Inversion Mutation Analysis, Whole Blood

First-tier molecular testing for male patients affected with severe hemophilia A when a variant has not been identified in the family Determining hemophilia A carrier status for at-risk female patients, ie, individuals with a family...

PRKSG - Overview: PRKAR1A Full Gene Sequencing with Deletion/Duplication, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of Carney Complex (CNC) or acrodysostosis-1 with hormone resistance Establishing a diagnosis of CNC or acrodysostosis-1 with hormone resistance