APIXA - Overview: Apixaban, Anti-Xa, Plasma

Measuring apixaban concentration in selected clinical situations (eg, renal insufficiency, assessment of compliance, periprocedural measurement of drug concentration, suspected overdose, advanced age, and extremes of body weight)

PALD - Overview: Aldosterone, Plasma

Investigation of primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter...

ALCU - Overview: Aluminum/Creatinine Ratio, Urine

Measurement of aluminum concentration as a part of assessing for aluminum exposure

APHTS - Overview: Amphiphysin Antibody Titer Assay, Serum

Evaluating patients with recent onset of a subacute neurological disorder for which a paraneoplastic basis might be suspected, particularly if the patient has a previous history, risk factors, or family history of cancer, especially lung or...

AERMC - Overview: Aeromonas Culture, Feces

Determining whether Aeromonas species may be the cause of diarrhea This test is generally not useful for patients hospitalized more than 3 days because the yield from specimens from these patients is very low, as is the likelihood of...

ABCRS - Overview: Alpha/Beta Crystallin IHC, Technical Component Only

Characterization of neuroectodermal tumors

APPI - Overview: Amyloid Precursor Protein (APP) Immunostain, Technical Component Only

Aids in the identification of amyloid precursor protein present in Alzheimer disease

ALDEF - Overview: Alpha Defensin, Lateral Flow Assay, Synovial Fluid

Detection of alpha defensins 1-3, human host response proteins, in synovial fluid of adults with a total joint replacement who are being evaluated for revision surgery This test is not intended to be used to determine timing for...

CCMVS - Overview: Congenital Cytomegalovirus (cCMV), Molecular Detection, PCR, Saliva

Aiding in the rapid diagnosis of cytomegalovirus (CMV) infections in neonates 21 days of age or younger using saliva specimens

CCMVU - Overview: Congenital Cytomegalovirus (cCMV), Molecular Detection, PCR, Urine

Aiding in the rapid diagnosis of cytomegalovirus infections in neonates 21 days of age or younger using urine specimens

HEMMF - Overview: Hematologic Specified FISH, Varies

The detection of specific chromosomal abnormalities in hematologic malignancies

HRPSV - Overview: Herpes Simplex Virus, I and II (HSV I and II) Immunostain, Technical Component Only

Identification of herpes simplex virus I and II infection

IGE - Overview: Immunoglobulin E (IgE), Serum

Evaluating patients with suspected diseases associated with elevations in total immunoglobulin E (IgE), including allergic disease, primary immunodeficiencies, infections, malignancies, or other inflammatory diseases Diagnostic evaluation...

AHDV - Overview: Hepatitis D Virus Total Antibodies, Serum

Detection of hepatitis D virus (HDV)-specific total antibodies (combined IgG and IgM) in human serum Diagnosis of concurrent HDV infection in patients with fulminant acute hepatitis B virus (HBV) infection (acute coinfection), chronic HBV...

HK36M - Overview: Histone H3 K36M Mutant (H3F3 K36M) Immunostain, Technical Component Only

Diagnosis of chondroblastoma

JCHAI - Overview: J-Chain Immunostain, Technical Component Only

Classification of lymphomas

FACTV - Overview: Coagulation Factor V Activity Assay, Plasma

Diagnosing congenital deficiencies (rare) of coagulation factor V Evaluating acquired deficiencies associated with liver disease, factor V inhibitors, myeloproliferative disorders, and intravascular coagulation and fibrinolysis...

F_2 - Overview: Coagulation Factor II Activity Assay, Plasma

Diagnosing a congenital deficiency (rare) of coagulation factor II Evaluating acquired deficiencies associated with liver disease or vitamin K deficiency, oral anticoagulant therapy, and antibody-induced deficiencies (eg, in association...

T790M - Overview: Cell-Free DNA EGFR T790M Mutation Analysis, Blood

Determination of EGFR T790M mutation status in blood specimens as an alternative to invasive tissue biopsies Identification of patients with non-small cell lung cancer who harbor a T790M mutation and may benefit from specific EGFR-targeted...

CRY_S - Overview: Cryoglobulin, Serum

Evaluating cryoglobulins in patients with vasculitis, glomerulonephritis, and lymphoproliferative diseases Evaluating cryoglobulins in patients with macroglobulinemia or myeloma in whom symptoms occur with cold exposure This test is not...

CDU - Overview: Cadmium, 24 Hour, Urine

Detecting exposure to cadmium, a toxic heavy metal, in 24-hour urine specimens

GATA3 - Overview: GATA Binding Protein 3 Immunostain, Technical Component Only

Characterizing carcinomas, including primary bladder and breast carcinomas, and some types of mesenchymal and neuroectodermal tumors

GAL1 - Overview: GALAD Score, Serum

Calculation of the GALAD (gender, age, alpha-fetoprotein L3% [AFP-L3], AFP, des-gamma-carboxy prothrombin) model score for hepatocellular carcinoma development in patients with chronic liver disease

GATAB - Overview: GATA-Binding Protein 3 Immunostain, Technical Component Only, Bone Marrow,

Characterizing carcinomas, including primary bladder and breast carcinomas, and some types of mesenchymal and neuroectodermal tumors

CSMRT - Overview: mSMART Plasma Cell Proliferative Disorder, Pre-Analysis Cell Sorting, Bone Marrow

Risk stratification of patients with multiple myeloma, which can assist in determining treatment and management decisions Sorting plasma cells for fluorescence in situ hybridization analysis Risk stratification of patients with newly...

FRAG - Overview: Osmotic Fragility, Erythrocytes

Evaluating suspected hereditary spherocytosis-associated hemolytic anemia Confirming or detecting mild spherocytosis

NBILI - Overview: Neonatal Bilirubin, Serum

Assessing liver function Evaluating a wide range of diseases affecting the production, uptake, storage, metabolism, or excretion of bilirubin Monitoring the efficacy of neonatal phototherapy

ORTHP - Overview: Orthostatic Proteinuria, Random, Urine

Diagnosis of orthostatic proteinuria

NAPSN - Overview: Napsin A Immunostain, Technical Component Only

Identification of primary lung adenocarcinoma

PSGN - Overview: Plasminogen Activity, Plasma

Evaluating patients with ligneous conjunctivitis (strong association with homozygous plasminogen deficiency) Evaluating fibrinolysis, in combination with other components of the fibrinolytic system (fibrinogen, tissue...

PIT1 - Overview: PIT-1 Immunostain, Technical Component Only

Classification of pituitary adenomas

PCTTS - Overview: Purkinje Cell Cytoplasmic Antibody Type Tr (PCA-Tr) Titer, Serum

Serological testing for Purkinje cell cytoplasmic antibody-Tr for patients with acquired cerebellar ataxia of undetermined etiology, particularly if the patient has a history of Hodgkin lymphoma Reporting an end titer result from serum...

RPTU1 - Overview: Protein/Creatinine Ratio, Random, Urine

Evaluation of renal disease Screening for monoclonal gammopathy

QFEVR - Overview: Q Fever Antibody Screen with Titer Reflex, Serum

Screening for exposure to Coxiella burnetii, the causative agent of Q fever This test should not be used as a screening procedure for the general population.

RB1 - Overview: Retinoblastoma Protein (Rb) Immunostain, Tech Only

Aids in the identification of high-grade neuroendocrine carcinomas and small cell carcinomas

P53 - Overview: p53 Immunostain, Technical Component Only

Aiding in the identification of neoplastic cells

PROG - Overview: Progesterone Receptor (PR) Immunostain, Technical Component Only

Qualitative detection of progesterone receptor protein in a diagnostic setting

P16 - Overview: p16 (INK4a/CDKN2A) Immunostain, Technical Component Only

Aids in the identification of human papilloma virus infection

PHTDP - Overview: Phosphorylated TDP43 Immunostain, Technical Component Only

Identification of pathological forms of TDP-43 in neurodegenerative diseases

POWV - Overview: Powassan Virus, IgM, Enzyme-Linked Immunosorbent Assay, Serum

Diagnosis of Powassan virus infection. This test should not be used as a screening procedure for the general population. This test should not be used as a "test of cure."

PIK3T - Overview: PIK3CA Mutation Analysis, Tumor

Identification of hormone receptor positive and human epidermal growth factor receptor 2 negative (HR+/HER2-) advanced breast cancer tumors that may be eligible for treatment with targeted kinase inhibitor therapy (eg, alpelisib).

CRYPS - Overview: Cryptosporidium Antigen, Feces

Establishing the diagnosis of intestinal cryptosporidiosis

CUT - Overview: Copper, Liver Tissue

Diagnosing Wilson disease and primary biliary cirrhosis using liver tissue specimens

CD279 - Overview: CD279 (PD-1) Immunostain, Technical Component Only

Identification of follicular T helper cells Phenotyping of angioimmunoblastic T-cell lymphoma

DSGAB - Overview: Desmoglein 1 (DSG1) and Desmoglein 3 (DSG3), IgG Antibodies, Serum

Preferred screening test for patients suspected to have an autoimmune blistering disorder of the skin or mucous membranes (pemphigus) Aiding in the diagnosis of pemphigus

ETGSR - Overview: Ethyl Glucuronide Screen with Reflex, Random, Urine

Screening for drug abuse involving alcohol

CDUOE - Overview: Cadmium Occupational Exposure, Random, Urine

Detecting occupational exposure to cadmium, a toxic heavy metal, using random urine specimens

CARFT - Overview: Carbamazepine, Free and Total, Serum

Monitoring carbamazepine (free and total) therapy in patients who are uremic

IHCFH - Overview: Fumarate Hydratase Immunostain, Technical Component Only

Identifying fumarate hydratase-deficient neoplasms Supporting the diagnosis of an atypical smooth muscle tumor over leiomyosarcoma

GFATC - Overview: Glial Fibrillary Acidic Protein Alpha Subunit Antibody, Immunofluorescence Titer Assay, Spinal Fluid

Reporting an end titer result in spinal fluid specimens Distinguishing, in spinal fluid, autoimmune GFAP astrocytopathy from infectious meningoencephalitis and idiopathic inflammatory central nervous system (CNS) disorders such as multiple...