BIOTS - Overview: Biotinidase, Serum

Preferred test for the diagnosis of biotinidase deficiency Follow-up testing for certain organic acidurias

CD303 - Overview: CD303 (BDCA-2) Immunostain, Technical Component Only

Diagnosis of blastic plasmacytoid dendritic cell neoplasm

CD4I - Overview: CD4 Immunostain, Technical Component Only

Identification of T helper cells, histiocytes, and monocytes

CAIX - Overview: Carbonic Anhydrase IX (CA-IX) Immunostain, Technical Component Only

Diagnosis of clear cell renal cell carcinoma and clear cell papillary renal cell carcinoma

MESOP - Overview: Mesothelioma Panel (WT1/KRT5/TTF1/pCEA) Immunostain, Technical Component Only

Differentiation of mesothelioma and non-small cell lung cancer

SGSS - Overview: Synthetic Glucocorticoid Screen, Serum

Confirming the presence of listed synthetic glucocorticoids (see Interpretation) Confirming the cause of secondary adrenal insufficiency This test is not useful for detection of fluticasone propionate.

SUDC - Overview: Sudden Cardiac Death Pathology Consultation

Identifying specific causes contributing to sudden cardiac death

SDHB - Overview: SDHB Immunostain, Technical Component Only

Aids in the identification of succinate dehydrogenase B-deficient tumors

NSEI - Overview: Neuron-Specific Enolase Immunostain, Technical Component Only

Characterization of neuroendocrine differentiation in tumors

SSX18 - Overview: Synovial Sarcoma Panel, Technical Component Only

Aiding in distinguishing synovial sarcomas from similar sarcomas

SV40 - Overview: SV40 Immunostain, Technical Component Only

Identifying BK or JC polyomavirus

CYSQN - Overview: Cystinuria Profile, Quantitative, 24 Hour, Urine

Diagnosis of cystinuria using 24-hour urine collections

CTFNA - Overview: Cytology Fine-Needle Aspiration, Varies

Detection of malignancy Detection of certain inflammatory conditions

CDKPB - Overview: CD68 (KP1) Immunostain, Bone Marrow, Technical Component Only

Aiding in the identification of histocytic and myeloid lineage cells

PGM1 - Overview: CD68 (PG-M1) Immunostain, Technical Component Only

Identification of monocytic differentiation Phenotyping hematolymphoid neoplasms that are suspected to represent histiocytic sarcomas

CHRO - Overview: Chromogranin Immunostain, Technical Component Only

Aiding in the identification of tumors with neuroendocrine differentiation

CA153 - Overview: Cancer Antigen 15-3 (CA 15-3), Serum

Managing breast cancer patients when used in conjunction with clinical information and other diagnostic procedures Serial testing to assist in early detection of disease recurrence in previously treated stage II and III breast cancer...

CLZ - Overview: Clozapine, Serum

Monitoring patient compliance of clozapine treatment An aid to achieving desired serum levels

CBBRP - Overview: Coxiella burnetii (Q fever), Molecular Detection, PCR, Blood

Aiding in the diagnosis of Coxiella burnetii infection (eg, Q fever)

CRT24 - Overview: Creatinine, 24 Hour, Urine

Urinary creatinine, in conjunction with serum creatinine, is used to calculate the creatinine clearance, a measure of renal function Normalizing urinary analytes to account for the variation in urinary concentration

CD14I - Overview: CD14 Immunostain, Technical Component Only

Marker of histiocytic and monocytic lineage and follicular dendritic cells

CALPN - Overview: Calponin Immunostain, Technical Component Only

Marker for myoepithelium when differentiating ductal carcinomas in situ from infiltrating breast carcinoma Characterization of tumors of smooth muscle or myoepithelial lineage

COLIV - Overview: Collagen IV Immunostain, Technical Component Only

A marker of the basal lamina of capillaries and basement membranes in all organs

CD19I - Overview: CD19 Immunostain, Technical Component Only

Identification of normal and neoplastic B cells

CD57 - Overview: CD57 Immunostain, Technical Component Only

Marker of natural killer cells and a subset of follicular T helper cells Aiding in the identification of tumors of neuroectodermal origin

CD163 - Overview: CD163 Immunostain, Technical Component Only

Identification of cells of monocytic/histiocytic lineage, expressed late in maturation

C5FX - Overview: C5 Complement, Functional, Serum

Diagnosis of C5 deficiency Investigation of a patient with an undetectable total complement level

C8FX - Overview: C8 Complement, Functional, Serum

Diagnosis of C8 deficiency Investigation of a patient with an undetectable total hemolytic complement level

C6FX - Overview: C6 Complement, Functional, Serum

Diagnosis of C6 deficiency Investigation of a patient with an undetectable total complement level

TICU - Overview: Titanium/Creatinine Ratio, Urine

Measurement of titanium concentration as part of a profile to assess exposure and elimination of titanium

RPTU1 - Overview: Protein/Creatinine Ratio, Random, Urine

Evaluation of renal disease Screening for monoclonal gammopathy

STLPC - Overview: St. Louis Encephalitis Antibody Panel, IgG and IgM, Spinal Fluid

Aiding the diagnosis of St. Louis encephalitis using spinal fluid specimens

OPATM - Overview: Opiate Confirmation, Meconium

Detecting maternal prenatal opiate/opioid use up to 5 months before birth

PAS3 - Overview: Pediatric Allergy Screen <3 Years, Serum

Establishing a diagnosis of an allergy to egg whites, milk, wheat, soybeans, and house dust mites Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or...

GNMTC - Overview: Macro/Microthrombocytopenia Gene Panel, Next-Generation Sequencing, Varies

Evaluating hereditary macro- or microthrombocytopenia disorders in patients with a personal or family history suggestive of a hereditary macro- or microthrombocytopenia disorder Diagnosing hereditary macro- or microthrombocytopenia...

CDCOM - Overview: Celiac Disease Comprehensive Cascade, Serum and Whole Blood

Evaluating patients suspected of having celiac disease, including patients with compatible symptoms, patients with atypical symptoms, and individuals at increased risk (family history, previous diagnosis with associated...

GNBLF - Overview: Bleeding Disorders, Focused Gene Panel, Next-Generation Sequencing, Varies

Evaluating hereditary bleeding in patients with a personal or family history suggestive of a hereditary bleeding disorder and initial laboratory testing results are suggestive for factors VII, VIII, IX, or XI deficiency, or a von Willebrand...

PMLR - Overview: PML::RARA Quantitative, PCR, Varies

Diagnosis of acute promyelocytic leukemia (APL) Detection of residual or recurrent APL Monitoring the level of PML::RARA (promyelocytic leukemia/retinoic acid receptor alpha) in APL patients

IDENT - Overview: Organism Referred for Identification, Aerobic Bacteria

Identification of pure isolates of aerobic bacteria Differentiation of members of the Staphylococcus aureus complex (S aureus, Staphylococcus argenteus, Staphylococcus schweitzeri)

PKUSC - Overview: Phenylalanine and Tyrosine, Self-Collect, Blood Spot

Monitoring effectiveness of therapy in patients with hyperphenylalaninemia in a patient-collected specimen This test is not sufficient for follow-up for abnormal newborn screening results or for establishing a diagnosis of a specific...

PSAU - Overview: Prostate-Specific Antigen (PSA) Ultrasensitive, Serum

As an aid in the detection of prostate cancer when used in conjunction with a digital rectal exam in men ages 50 years and older To aid in the prognosis and management of individuals diagnosed with prostate cancer Monitoring disease after...

T3 - Overview: T3 (Triiodothyronine), Total, Serum

Second-order testing for hyperthyroidism in patients with low thyroid-stimulating hormone values and normal thyroxine levels Diagnosing triiodothyronine (T3) toxicosis This test is not useful for general screening of the population...

7AC4 - Overview: 7AC4, Bile Acid Synthesis, Serum

Screening for bile acid malabsorption in patients with irritable bowel syndrome with diarrhea

VWFMS - Overview: von Willebrand Factor Multimer Analysis, Plasma

Resolving discrepancies when results of complementary laboratory tests (eg, F8A / Coagulation Factor VIII Activity Assay, Plasma; VWACT / von Willebrand Factor Activity, Plasma; and VWAG / von Willebrand Factor Antigen, Plasma) are...

ASMW - Overview: Acid Sphingomyelinase, Leukocytes

Investigation of possible diagnosis of Niemann-Pick disease types A and B This test is not recommended for carrier detection because of the wide range of enzymatic activities observed in carriers and noncarriers.

RNP - Overview: RNP Antibodies, IgG, Serum

Evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive Testing for ribonucleoprotein particle antibodies is not useful in patients without demonstrable...

HRTVC - Overview: Heartland Virus, RNA, Molecular Detection, PCR, Spinal Fluid

Aiding in the diagnosis of central nervous system infection caused by Heartland virus using spinal fluid specimens

HEX4 - Overview: Glucotetrasaccharides, Random, Urine

Diagnosing Pompe disease, when used in conjunction with acid alpha-glucosidase enzyme activity assays and molecular genetic analysis of the GAA gene Monitoring patients with Pompe disease on enzyme replacement therapy May support the...

ALDNA - Overview: Aldosterone with Sodium, 24 Hour, Urine

Investigating primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (eg, renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter...

L3AFP - Overview: Alpha-Fetoprotein (AFP) L3% and Total, Hepatocellular Carcinoma Tumor Marker, Serum

Distinguishing between hepatocellular carcinoma and chronic liver disease Monitoring individuals with hepatic cirrhosis from any etiology for progression to hepatocellular carcinoma Surveillance for development of hepatocellular...