HPFH - Overview: Hemoglobin F Distribution, Blood

Distinguishing large deletional hereditary persistence of fetal hemoglobin from other conditions with increased percentage of fetal hemoglobin (Hb F) Determining the distribution of Hb F within red blood cells

UHBAG - Overview: Histoplasma and Blastomyces Antigen, Enzyme Immunoassay, Urine

Diagnosing Histoplasma capsulatum or Blastomyces dermatitidis infection, without differentiation between the organisms, using random urine specimens Monitor antigen levels following initiation of antifungal treatment

NMH1D - Overview: N-Methylhistamine, 24 Hour, Urine

Screening for and monitoring of mastocytosis and disorders of systemic mast-cell activation, such as anaphylaxis and other forms of severe systemic allergic reactions as a part of a profile Monitoring therapeutic progress in conditions...

NMHR1 - Overview: N-Methylhistamine, Random, Urine

Screening for and monitoring of mastocytosis and disorders of systemic mast-cell activation, such as anaphylaxis and other forms of severe systemic allergic reactions as a part of a random urine collection profile Monitoring therapeutic...

NIS - Overview: Nickel, Serum

Confirmation of an elevated urinary nickel concentration This test is not useful for the investigation of nickel hypersensitivity.

NIUCR - Overview: Nickel/Creatinine Ratio, Random, Urine

Preferred specimen type for biomonitoring nickel exposure

OPTU - Overview: Orthostatic Protein, Timed Collection, Urine

Diagnosis of orthostatic proteinuria As a second-order test for additional characterization of proteinuria of less than 3 grams/24 hours, particularly in children or adolescents

OPE - Overview: Ova and Parasite, Travel History or Immunocompromised, Feces

Detecting and identifying parasitic protozoa and eggs and larvae of parasitic helminths in stool specimens

PBGD_ - Overview: Porphobilinogen Deaminase, Whole Blood

Confirmation of a diagnosis of acute intermittent porphyria

PC2TS - Overview: Purkinje Cell Cytoplasmic Antibody Type 2 (PCA-2) Titer, Serum

Evaluating patients who present with a subacute neurological disorder of undetermined etiology and have risk factors for lung cancer Reporting an end titer result from serum specimens

PRCAL - Overview: Procalcitonin, Serum

Monitoring antibiotic therapy and all-cause mortality for patients diagnosed with severe sepsis or septic shock in the Intensive Care Unit (ICU) or when obtained in the emergency department or other medical wards prior to ICU admission

PRSSZ - Overview: PRSS1 Gene, Full Gene Analysis, Varies

Confirmation of suspected clinical diagnosis of hereditary pancreatitis (HP) in patients with chronic pancreatitis Identification of familial PRSSI mutation to allow for predictive and diagnostic testing in family members

ROMA - Overview: ROMA Score (Ovarian Malignancy Risk Algorithm), Serum

Risk assessment for finding an ovarian malignancy during surgery in women who present with an adnexal mass The test is not intended as a screening or stand-alone diagnostic assay for ovarian cancer.

PARVP - Overview: Parvovirus B19, Molecular Detection, PCR, Plasma

Diagnosing parvovirus B19 infection in plasma specimens

SHIGC - Overview: Shigella Culture, Feces

Determining whether Shigella species may be the cause of diarrhea Reflexive testing for Shigella species from nucleic acid amplification test-positive stool This test is generally not useful for patients hospitalized more than 3 days...

DHTS - Overview: Dihydrotestosterone, Serum

Monitoring patients receiving 5-alpha reductase inhibitor therapy or chemotherapy Evaluating patients with possible 5-alpha reductase deficiency

COWB - Overview: Cobalt, Blood

Monitoring exposure to cobalt using whole blood specimens Monitoring metallic prosthetic implant wear This test is not useful for assessment of vitamin B12 activity.

SFIG - Overview: Cerebrospinal Fluid IgG Index Profile, Serum and Spinal Fluid

Aiding in the diagnosis of multiple sclerosis and other central nervous system inflammatory conditions

CORTF - Overview: Cortisol, Free, Serum

Assessment of cortisol status in cases where there is known or a suspected abnormality in cortisol-binding proteins or albumin Assessment of adrenal function in the critically ill or stressed patient, thus preventing unnecessary use of...

CARTF - Overview: Carbamazepine Profile, Serum

Monitoring patients exhibiting symptoms of carbamazepine toxicity whose total serum carbamazepine concentration is within the therapeutic range, but who may be producing significant levels of the active metabolite epoxide Free...

ERPR - Overview: Estrogen/Progesterone Receptor, Semi-Quantitative Immunohistochemistry, Manual

Guiding decisions on hormonal therapy in patients with breast carcinomas This test is not useful for cases of lobular carcinoma in situ.

FFRWB - Overview: Friedreich Ataxia, Frataxin, Quantitative, Blood

Diagnosing individuals with Friedreich ataxia in whole blood specimens Monitoring frataxin levels in patients with Friedreich ataxia This test is not useful for carrier detection.

GMCSF - Overview: Granulocyte Monocyte-Colony Stimulating Factor, Plasma

Measuring the concentration of granulocyte macrophage-colony stimulating factor (GM-CSF) in plasma Understanding the etiology of chronic inflammatory diseases or infections, when used in conjunction with clinical information and other...

LEGRP - Overview: Legionella species, Molecular Detection, PCR, Varies

Sensitive and rapid diagnosis of pneumonia caused by Legionella species The assay is not recommended as a test of cure because bacteria nucleic acids may persist after successful treatment.

MPS3W - Overview: Mucopolysaccharidosis III, Four-Enzyme Panel, Leukocytes

Supporting the biochemical diagnosis of mucopolysaccharidoses types IIIA, IIIB, IIIC, IIID This test is not useful for carrier detection.

KKRP - Overview: Kingella kingae, Molecular Detection, PCR, Varies

Aiding in the diagnosis of Kingella kingae infection using tissue or synovial fluid specimens

MSDW - Overview: Multiple Sulfatase Deficiency, Leukocytes

Supporting the biochemical diagnosis of multiple sulfatase deficiency in whole blood specimens This test is not useful for carrier detection.

UPGC - Overview: Uroporphyrinogen III Synthase (Co-Synthase), Erythrocytes

Diagnosis of congenital erythropoietic porphyria This test is not useful for diagnosis of acute intermittent porphyria (AIP).

TIWB - Overview: Titanium, Blood

Detecting and monitoring titanium exposure and potential implant status in patients with orthopedic implants

MTRNA - Overview: Trichomonas vaginalis, Nucleic Acid Amplification, Varies

Detecting Trichomonas vaginalis in prostatic massage (VBIII) fluid or male urethral swabs

TSTIM - Overview: Targeted Stimulant Screen, Random, Urine

Aiding in the determination of compliance or identify illicit stimulant drug use This test is not intended for use in employment-related testing.

VWFMP - Overview: von Willebrand Factor Multimer Analysis, Plasma

As a reflex component of several coagulation consultation unit codes, when indicated When results of complementary laboratory tests are abnormally low or discordant (eg, F8A / Coagulation Factor VIII Activity Assay, Plasma; VWACT / von...

GLP - Overview: Glucagon, Plasma

Diagnosis and follow-up of glucagonomas and other glucagon-producing tumors Assessing diabetic patients with problematic hyper- or hypoglycemic episodes (extremely limited utility)

23BPR - Overview: 2,3-Dinor 11 Beta-Prostaglandin F2 Alpha, Random, Urine

Screening for mast cell activation disorders including systemic mastocytosis using random urine specimens

AFPSF - Overview: Alpha-Fetoprotein (AFP), Spinal Fluid

An adjunct in the diagnosis of central nervous system (CNS) germinomas and meningeal carcinomatosis Evaluating the presence of germ-cell tumors in the CNS, in conjunction with cerebrospinal fluid (CSF) beta-human chorionic gonadotropin...

TSPU - Overview: Targeted Stimulant Screen, Random, Urine

Determining compliance or identifying illicit stimulant drug use This test is not intended for employment-related testing.

DASM4 - Overview: Drugs of Abuse Screen, Meconium 4

Identifying amphetamines (and methamphetamines), opiates, as well as metabolites of cocaine and marijuana in meconium specimens

NICOU - Overview: Nicotine and Metabolites, Random, Urine

Monitoring tobacco use Monitoring patients on nicotine-replacement therapy for concurrent use of tobacco products

T4FT4 - Overview: T4 (Thyroxine), Total and Free, Serum

Assessing thyroid function when thyroid function disorders are suspected

FFTST - Overview: Testosterone, Free and Weakly Bound, With Total Testosterone, LC/MS-MS

Free and weakly bound testosterone (FWBT), also referred to as bioavailable testosterone, is thought to reflect an individual's biologically active, circulating testosterone. FWBT includes free testosterone and testosterone that is bound to...

EMAIG - Overview: Endomysial Antibodies, IgG, Serum

Analysis of IgG-endomysial antibodies for the diagnosis of dermatitis herpetiformis and celiac disease Monitoring adherence to gluten-free diet in patients with dermatitis herpetiformis and celiac disease

PKU - Overview: Phenylalanine and Tyrosine, Plasma

Monitoring effectiveness of dietary therapy in patients with hyperphenylalaninemia

BLBLF - Overview: B-Cell Lymphoblastic Leukemia/Lymphoma, FISH, Tissue

Detecting, at diagnosis, recurrent common chromosome abnormalities associated with B-cell acute lymphoblastic leukemia/lymphoma (B-ALL/LBL) and Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) in paraffin-embedded...

AMLPF - Overview: Acute Myeloid Leukemia (AML), FISH, Pediatric, Varies

This test should not be used to screen for residual acute myeloid leukemia (AML). Useful at diagnosis for detecting recurrent common chromosome abnormalities in pediatric patients with AML An adjunct to chromosome studies in patients with...

NF1Z - Overview: Neurofibromatosis Type 1, NF1, Full Gene Analysis, Varies

Evaluating patients with a personal or family history suggestive of neurofibromatosis type 1 (NF1) Establishing a diagnosis of a NF1 allowing for targeted cancer surveillance based on associated risks Identifying genetic variants...

GNPLT - Overview: Platelet Disorders, Comprehensive Gene Panel, Next-Generation Sequencing, Varies

Evaluating hereditary platelet disorders in patients with a personal or family history suggestive of a hereditary platelet disorder Diagnosing hereditary platelet disorders for patients in whom phenotypic testing is nondiagnostic, but...

MITOP - Overview: Mitochondrial Full Genome Analysis, Next-Generation Sequencing (NGS), Varies

Diagnosis of the subset of mitochondrial diseases that result from variants in the mitochondrial genome A second-tier test for patients in whom previous targeted gene variant analyses for specific mitochondrial disease-related genes were...

COGMF - Overview: Acute Myeloid Leukemia (AML), Children's Oncology Group Enrollment Testing, FISH, Varies

Evaluation of pediatric bone marrow and peripheral blood specimens by fluorescence in situ hybridization (FISH) probe analysis for classic rearrangements and chromosomal copy number changes associated with acute myeloid leukemia (AML) in...

CGAK - Overview: Chromogranin A, Serum

Aiding in monitoring disease progression during the course of disease and treatment in patients with gastroenteropancreatic neuroendocrine tumors (grade 1 and grade 2) when used in conjunction with other clinical methods This test is not...

U1A1Q - Overview: Uridine Diphosphate (UDP) Glucuronosyltransferase 1A1 TA Repeat Genotype, UGT1A1, Varies

Identifying individuals who are at increased risk of adverse drug reactions with drugs that are metabolized by uridine diphosphate glucuronosyltransferase (UGT1A1); especially irinotecan but also atazanavir, nilotinib, pazopanib, and...