SEP9Z - Overview: SEPTIN9 Gene, Full Gene Analysis, Varies
Establishing a molecular diagnosis for patients with hereditary neuralgic amyotrophy Identifying variants within SEPTIN9 known to be associated with hereditary neuralgic amyotrophy, allowing for predictive testing of at-risk family members
Screening for infection with high-risk human papillomavirus (HPV) associated with the development of cervical cancer Individual genotyping of HPV-16 and/or HPV-18 if present This testing is intended for use in clinical monitoring and...
Detecting drug use involving stimulants, barbiturate, benzodiazepines, cocaine, opioids, and tetrahydrocannabinol This test is not intended for use in employment-related testing.
CSMPU - Overview: Controlled Substance Monitoring Panel, Random, Urine
Detecting drug use involving stimulants, barbiturates, benzodiazepines, cocaine, opioids, and tetrahydrocannabinol This test is not intended for use in employment-related testing.
PCAG - Overview: Protein C Antigen, Plasma
Differentiating congenital type I protein C deficiency from type II deficiency Evaluating the significance of decreased functional protein C, especially when decreased protein C activity might be congenital rather than acquired (eg, due...
HEXAZ - Overview: Tay-Sachs Disease, HEXA Gene, Full Gene Analysis, Varies
Second-tier test for confirming a biochemical diagnosis of Tay-Sachs disease (TSD) Carrier testing of individuals with a family history of TSD but an affected individual is not available for testing or disease-causing mutations have not...
WNMC - Overview: West Nile Virus Antibody, IgM, Spinal Fluid
Aids in diagnosing central nervous system West Nile virus infections during the acute phase
GDF15 - Overview: Growth Differentiation Factor 15, Plasma
A circulating biomarker in myopathy-related mitochondrial disease as well as other conditions Investigation of patients suspected of having a mitochondrial myopathy This assay is not suitable for carrier detection.
ETGX - Overview: Ethyl Glucuronide Confirmation, Chain of Custody, Random, Urine
Monitoring abstinence in clinical and justice system settings using ethyl glucuronide and ethyl sulfate as direct biomarkers or metabolites of ethanol This chain-of-custody test is intended to be used in a setting where the test results...
AHDV - Overview: Hepatitis D Virus Total Antibodies, Serum
Detection of hepatitis D virus (HDV)-specific total antibodies (combined IgG and IgM) in human serum Diagnosis of concurrent HDV infection in patients with fulminant acute hepatitis B virus (HBV) infection (acute coinfection), chronic HBV...
RISA - Overview: Risankizumab, Serum
Assessing the response to risankizumab therapy Assessing the need for dose escalation Evaluating potential changes or discontinuation of therapy Monitoring patients who need to be above a certain risankizumab concentration to improve the...
ROXUR - Overview: Oxalate, Random, Urine
Monitoring therapy for kidney stones using random urine specimens Identifying increased urinary oxalate as a risk factor for stone formation Diagnosis of primary or secondary hyperoxaluria
HEVML - Overview: Hepatitis E Virus IgM Antibody Confirmation, Serum
Confirmation of reactive hepatitis E virus IgM antibody screening test results for the diagnosis of acute or recent (<6 months) hepatitis E infection
UHBAG - Overview: Histoplasma and Blastomyces Antigen, Enzyme Immunoassay, Urine
Diagnosing Histoplasma capsulatum or Blastomyces dermatitidis infection without differentiation between the organisms Monitor antigen levels following initiation of antifungal treatment
TULM - Overview: Francisella tularensis Antibody, IgM, ELISA, Serum
Evaluating the presence of IgM antibodies in patients with suspected tularemia caused by Francisella tularensis This test should not be used as a test of cure as it is not quantitative. Patients may remain seropositive for months to years...
TULG - Overview: Francisella tularensis Antibody, IgG, ELISA, Serum
Evaluating the presence of IgG antibodies in patients with suspected tularemia caused by Francisella tularensis This test should not be used as a test of cure as it is not quantitative. Patients may remain seropositive for months to years...
ACTH - Overview: Adrenocorticotropic Hormone, Plasma
Determining the cause of hypercortisolism and hypocortisolism
AN3TC - Overview: Antineuronal Nuclear Antibody Type 3 (ANNA-3) Titer, Spinal Fluid
Evaluating patients who present with a subacute neurological disorder of undetermined etiology and have risk factors for primary lung carcinoma Reporting an end titer result from cerebrospinal fluid specimens
ALDS - Overview: Aldosterone, Serum
Investigating primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter...
BILI3 - Overview: Bilirubin, Serum
Assessing liver function Evaluating a wide range of diseases affecting the production, uptake, storage, metabolism, or excretion of bilirubin Monitoring the efficacy of neonatal phototherapy
MRDMM - Overview: Multiple Myeloma Minimal Residual Disease, Flow Cytometry, Bone Marrow
Detecting low level (minimal residual disease) myeloma cells after therapy.
SLO - Overview: Smith-Lemli-Opitz Screen, Plasma
Diagnosing Smith-Lemli-Opitz syndrome (7-dehydrocholesterol reductase deficiency)
CARTF - Overview: Carbamazepine Profile, Serum
Monitoring patients exhibiting symptoms of carbamazepine toxicity whose total serum carbamazepine concentration is within the therapeutic range, but who may be producing significant levels of the active metabolite epoxide Free...
CEE20 - Overview: CD20 Cell Expression Evaluation, Varies
Detecting cell-surface antigens on malignant cells that are potential therapeutic antibody targets, specifically CD20 Determining the eligibility of patients for monoclonal antibody therapies Monitoring response to the therapeutic...
CEE49 - Overview: CD49d Cell Expression Evaluation, Varies
Detecting cell-surface antigens on malignant cells that are potential therapeutic antibody targets, specifically CD49d Determining the eligibility of patients for monoclonal antibody therapies Monitoring response to the therapeutic...
ETGR - Overview: Ethyl Glucuronide Screen with Reflex, Random, Urine
Screening and confirmation for drug abuse involving alcohol
OPTU - Overview: Orthostatic Protein, Timed Collection, Urine
Diagnosis of orthostatic proteinuria As a second-order test for additional characterization of proteinuria of less than 3 grams/24 hours, particularly in children or adolescents
Rapid detection of Mycobacterium tuberculosis DNA from respiratory specimens for the diagnosis of pulmonary tuberculosis Presumptive detection of rifampin resistance based on the presence of resistance-associated mutations
CHLM - Overview: Chlamydia IgM, Immunofluorescence, Serum
Assessing IgM antibody levels to aid in the clinical diagnosis of Chlamydia pneumoniae or Chlamydia psittaci infections
FUROC - Overview: UroVysion for Detection of Bladder Cancer, Urine
Monitoring for tumor recurrence in patients with a history of urothelial carcinoma involving the bladder or upper urinary tract Assessing patients with hematuria for urothelial carcinoma
AFPSF - Overview: Alpha-Fetoprotein (AFP), Spinal Fluid
An adjunct in the diagnosis of central nervous system (CNS) germinomas and meningeal carcinomatosis Evaluating the presence of germ-cell tumors in the CNS, in conjunction with cerebrospinal fluid (CSF) beta-human chorionic gonadotropin...
HVAR - Overview: Homovanillic Acid, Random, Urine
Screening children for catecholamine-secreting tumors using a random urine collection when requesting homovanillic acid only Monitoring neuroblastoma treatment Screening patients with possible inborn errors of catecholamine metabolism
OPTMX - Overview: Opiate Confirmation, Chain of Custody, Meconium
Detecting maternal prenatal opiate/opioid use up to 5 months before birth Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the...
FGHTP - Overview: Ghrelin Total (Plasma)
Ghrelin Total (Plasma)
ATR - Overview: Isoagglutinin Titer, Anti-A, Serum
Evaluation of individuals with possible hypogammaglobulinemia Investigation of suspected roundworm infections
BTR - Overview: Isoagglutinin Titer, Anti-B, Serum
Evaluation of individuals with possible hypogammaglobulinemia
ALT - Overview: Alanine Aminotransferase (ALT) (GPT), Serum
Diagnosis and monitoring of liver disease associated with hepatic necrosis
FNEU - Overview: Neurotransmitter Metabolites (5HIAA, HVA, 3OMD) (CSF)
Neurotransmitter Metabolites (5HIAA, HVA, 3OMD) (CSF)
EOSU1 - Overview: Eosinophils, Random, Urine
Investigation of possible acute interstitial nephritis
MEV0 - Overview: Methemoglobin Summary Interpretation
Incorporating and summarizing subsequent results into an overall interpretation for the MEV1 / Methemoglobinemia Evaluation, Blood
Providing a genetic evaluation for patients with a personal or family history suggestive of hereditary hemorrhagic telangiectasia (HHT), cerebral cavernous malformation (CCM), capillary malformation-arteriovenous malformation syndrome...
TALPF - Overview: T-Cell Acute Lymphoblastic Leukemia/Lymphoma (ALL), FISH, Pediatric, Varies
Detecting, at diagnosis, recurrent common chromosome abnormalities associated with T-cell acute lymphoblastic leukemia/lymphoma (T-ALL) in pediatric/young adult patients As an adjunct to conventional chromosome studies in pediatric/young...
Detecting drug use involving stimulants, barbiturate, benzodiazepines, cocaine, opioids, tetrahydrocannabinol, and alcohol This test is not intended for use in employment-related testing.
Confirming the diagnosis of dermatofibrosarcoma protuberans (DFSP)/giant cell fibroblastoma (GCF) and excluding other spindle neoplasms that closely simulate the DFSP histology, including dermatofibroma (benign fibrous histiocytoma),...
PDBS - Overview: Pompe Disease, Blood Spot
Evaluating patients with a clinical presentation suggestive of Pompe disease (muscle hypotonia, weakness, or cardiomyopathy) outside of the newborn screening setting
HGH - Overview: Growth Hormone, Serum
Diagnosis of acromegaly and assessment of treatment efficacy when interpreted in conjunction with results from glucose suppression test Diagnosis of human growth hormone deficiency when interpreted in conjunction with results from growth...
PTOX - Overview: Toxoplasma gondii, Molecular Detection, PCR, Varies
Supporting the diagnosis of acute cerebral, ocular, disseminated, or congenital toxoplasmosis This test should not be used to screen healthy patients.
PSYR - Overview: Psychosine, Whole Blood
Aiding in the biochemical diagnosis of Krabbe disease using whole blood specimens Follow-up of individuals affected with Krabbe disease Follow-up testing after an abnormal newborn screening result for Krabbe disease Monitoring of...
HBNTP - Overview: Hepatitis B Virus Surface Antigen Confirmation, Prenatal, Serum
Diagnosis of acute, recent, or chronic hepatitis B in prenatal patients This test is not useful during the "window period" of acute hepatitis B (ie, after disappearance of hepatitis B virus surface antigen [HBsAg] and prior to appearance...
GPSYW - Overview: Glucopsychosine, Blood
Second-tier test when newborn screening results with reduced beta-glucosidase (GBA) activity are identified Diagnosis and monitoring of patients with Gaucher disease using whole blood specimens Supporting the biochemical diagnosis of...
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....
Week in Review: November 1 - Insights
Top highlights include: Facebook launches into the digital space of healthcare, medical breakthrough for Ebola, and how the brain makes memories.