IA2 - Overview: Islet Antigen 2 (IA-2) Antibody, Serum

Clinical distinction of type 1 from type 2 diabetes mellitus Identification of individuals at risk of type 1 diabetes (including high-risk relatives of patients with diabetes) Prediction of future need for insulin treatment in...

PBU - Overview: Lead, 24 Hour, Urine

Detecting clinically significant lead exposure in 24-hour specimens This test is not a substitute for blood lead screening.

PBUCR - Overview: Lead/Creatinine Ratio, Random, Urine

Detecting clinically significant lead exposure, a toxic heavy metal, using random urine specimens

IODCU - Overview: Iodine/Creatinine Ratio, Random, Urine

Assessment of iodine toxicity or recent iodine exposure using a random urine collection Monitoring iodine excretion rate as index of replacement therapy

BCGR - Overview: Immunoglobulin Gene Rearrangement, Blood

Determining whether a B-cell or plasma cell population is polyclonal or monoclonal using whole blood specimens Identifying neoplastic cells as having B-cell or plasma cell differentiation Monitoring for a persistent neoplasm by...

FATF - Overview: Fat, Feces

Diagnosing fat malabsorption due to pancreatic or intestinal disorders Monitoring effectiveness of enzyme supplementation in certain malabsorption disorders This test is not useful for differentiating among pancreatic diseases.

LGBBS - Overview: Globotriaosylsphingosine, Blood Spot

Screening of patients with Fabry disease using dried blood spots when a serum specimen is not available This test should not be used for newborn screening followup.

GD65S - Overview: Glutamic Acid Decarboxylase (GAD65) Antibody Assay, Serum

Assessing susceptibility to autoimmune (type 1, insulin-dependent) diabetes mellitus and related endocrine disorders (eg, thyroiditis and pernicious anemia) Distinguishing between patients with type 1 and type 2 diabetes Confirming a...

GDS - Overview: Gadolinium, Serum

Aiding in documenting previous exposure to gadolinium-based contrast agents using serum specimens

HEVG - Overview: Hepatitis E Virus IgG Antibody, Serum

Diagnosis of past exposure to hepatitis E virus

MPLVS - Overview: MPL Exon 10 Mutation Detection, Varies

Aiding in the distinction between a reactive cytosis and a myeloproliferative neoplasm

MYD88 - Overview: MYD88, L265P, Somatic Gene Mutation, DNA Allele-Specific PCR, Varies

Establishing the diagnosis of lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia Helping to distinguish lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia (low-grade B-cell lymphoma) from other subtypes

NELL1 - Overview: Neural Epidermal Growth Factor-Like 1 Protein Immunostain, Technical Component Only

Identification of neural epidermal growth factor-like 1 (NELL-1) protein primary membranous nephropathy

MESOP - Overview: Mesothelioma Panel (WT1/KRT5/TTF1/pCEA) Immunostain, Technical Component Only

Differentiation of mesothelioma and non-small cell lung cancer

MRDMR - Overview: Multiple Myeloma Minimal Residual Disease by Flow Cytometry, Bone Marrow

Detecting low level (minimal residual disease) myeloma cells after therapy to confirm remission has been achieved

HG - Overview: Mercury, Blood

Detecting mercury toxicity

CTBBL - Overview: Mycobacterial Culture, Blood

Diagnosing mycobacteremia

PINP - Overview: Procollagen I Intact N-Terminal, Serum

Aiding in monitoring antiresorptive and anabolic therapy in patients with osteoporosis An adjunct in the assessment of conditions associated with increased bone turnover, such as Paget disease This test should not be used as a screening...

PRL - Overview: Prolactin, Serum

Aiding in evaluation of pituitary tumors, amenorrhea, galactorrhea, infertility, and hypogonadism Monitoring therapy of prolactin-producing tumors

PCPMX - Overview: Phencyclidine (PCP) Confirmation, Chain of Custody, Meconium

Detection of in utero drug exposure up to 5 months before birth Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen...

PLP - Overview: Pyridoxal 5-Phosphate, Plasma

Determining vitamin B6 status, including in persons who present with progressive nerve compression disorders, such as carpal tunnel and tarsal tunnel syndromes Determining the overall success of a vitamin B6 supplementation...

SES - Overview: Selenium, Serum

Monitoring selenium replacement therapy

TPO - Overview: Thyroperoxidase Antibodies, Serum

Aiding in the diagnosis of thyroid autoimmune disorders Differentiating thyroid autoimmune disorders from nonautoimmune goiter or hypothyroidism As a diagnostic tool in deciding whether to treat a patient who has subclinical...

WHIPB - Overview: Tropheryma whipplei, Molecular Detection, PCR, Blood

Aiding in the diagnosis of Whipple disease, especially for identifying inconclusive or suspicious cases, using whole blood specimens

SCERA - Overview: Saccharomyces cerevisiae Antibody, IgA, Serum

Measuring IgA anti-Saccharomyces cerevisiae antibodies as a part of a profile to aid in distinguishing between ulcerative colitis and Crohn disease in patients for whom the specific diagnosis is unclear based on endoscopic, pathologic, and...

SABP - Overview: Streptococcal Antibodies Profile, Serum

Demonstration of acute or recent streptococcal infection using both antistreptolysin O and anti-DNase B titers

SGSS - Overview: Synthetic Glucocorticoid Screen, Serum

Confirming the presence of listed synthetic glucocorticoids (see Interpretation) Confirming the cause of secondary adrenal insufficiency This test is not useful for detection of fluticasone propionate.

SGSU - Overview: Synthetic Glucocorticoid Screen, Random, Urine

Confirming the presence of the listed synthetic glucocorticoids Confirming the cause of secondary adrenal insufficiency

FUROC - Overview: UroVysion for Detection of Bladder Cancer, Urine

Monitoring for tumor recurrence in patients with a history of urothelial carcinoma involving the bladder or upper urinary tract Assessing patients with hematuria for urothelial carcinoma

HK36M - Overview: Histone H3 K36M Mutant (H3F3 K36M) Immunostain, Technical Component Only

Diagnosis of chondroblastoma

OCT2 - Overview: OCT-2 Immunostain, Technical Component Only

Classification of lymphomas

THCMX - Overview: 11-nor-Delta-9-Tetrahydrocannabinol-9-Carboxylic Acid (Carboxy-THC) Confirmation, Chain of Custody, Meconium

Detecting in utero drug exposure to marijuana (tetrahydrocannabinol) up to 5 months before birth Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the...

APPI - Overview: Amyloid Precursor Protein (APP) Immunostain, Technical Component Only

Aids in the identification of amyloid precursor protein present in Alzheimer disease

CD279 - Overview: CD279 (PD-1) Immunostain, Technical Component Only

Identification of follicular T helper cells Phenotyping of angioimmunoblastic T-cell lymphoma

ASCL1 - Overview: Achaete-Scute Homolog 1 (ASCL1) Immunostain, Technical Component Only

Identification of the presence of achaete-scute homolog 1 (ASCL1)

ALKOT - Overview: Anaplastic Lymphoma Kinase (ALK [OTI1A4]) Immunostain, Technical Component Only

Identification of anaplastic lymphoma kinase overexpression Diagnosis of inflammatory myofibroblastic tumor and anaplastic large cell lymphoma

VIBC - Overview: Vibrio Culture, Feces

Determining whether Vibrio species may be the cause of diarrhea This test is generally not useful for patients that have been hospitalized for more than 3 days because the yield from these patients' specimens is very low, as is the...

MUCN2 - Overview: Mucin 2, Immunostain, Technical Component Only

Aiding in subtyping intraductal papillary mucinous neoplasms

ESTR - Overview: Estrogen Receptor Immunostain, Technical Component Only

Qualitative detection of estrogen receptor alpha protein in a diagnostic setting

HRPSV - Overview: Herpes Simplex Virus, I and II (HSV I and II) Immunostain, Technical Component Only

Identification of herpes simplex virus I and II infection

JCHAI - Overview: J-Chain Immunostain, Technical Component Only

Classification of lymphomas

PROG - Overview: Progesterone Receptor (PR) Immunostain, Technical Component Only

Qualitative detection of progesterone receptor protein in a diagnostic setting

NAPSN - Overview: Napsin A Immunostain, Technical Component Only

Identification of primary lung adenocarcinoma

UBIQ - Overview: Ubiquitin (UBIQ) Immunostain, Technical Component Only

Classification of neurodegenerative diseases

TB1LN - Overview: Antimicrobial Susceptibility, Mycobacterium tuberculosis Complex, First Line, Varies

Susceptibility testing of Mycobacterium tuberculosis complex isolates growing in pure culture.

NEPHP - Overview: Comprehensive Nephrology Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of hereditary kidney disease Establishing a diagnosis for a variety of hereditary kidney conditions including focal segmental glomerulosclerosis,...

HHTGG - Overview: Hereditary Hemorrhagic Telangiectasia and Vascular Malformations Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of hereditary hemorrhagic telangiectasia (HHT), cerebral cavernous malformation (CCM), capillary malformation-arteriovenous malformation syndrome...

PCDES - Overview: Pediatric Autoimmune Encephalopathy/CNS Disorder Evaluation, Serum

Evaluating children with autoimmune central nervous system disorders using serum specimens

A1APP - Overview: Alpha-1-Antitrypsin Phenotype, Serum

Identification of homozygous and heterozygous phenotypes of the alpha-1-antitrypsin deficiency

AFPA - Overview: Alpha-Fetoprotein, Amniotic Fluid

Screening for open neural tube defects or other fetal abnormalities Follow-up testing for patients with elevated serum alpha-fetoprotein results or in conjunction with cytogenetic testing