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ERG - Overview: ERG Immunostain, Technical Component Only

Identification of erythroblast transformation specific (ETS)-related gene (ERG) protein expression

FC13A - Overview: Factor 13a Immunostain, Technical Component Only

Aiding in the identification of acquired digital fibrokeratomas, angiofibromas, and oral fibroma, and a proportion of cells in histiocytomas

P57I - Overview: p57 (KIP2/CDKN1C) Immunostain, Technical Component Only

Aids in the identification of cytotrophoblasts, intermediate trophoblasts, and villous stromal cells

CRDPS - Overview: Creatine Disorders Panel, Serum

Evaluating patients with a clinical suspicion of arginine:glycine amidinotransferase deficiency,guanidinoacetate methyltransferase deficiency, and creatine transporter deficiency using serum specimens

CRDPP - Overview: Creatine Disorders Panel, Plasma

Evaluating patients with a clinical suspicion of arginine:glycine amidinotransferase deficiency, guanidinoacetate methyltransferase deficiency, and creatine transporter deficiency using plasma specimens

COMID - Overview: Combined Humoral and Cell-Mediated Immunodeficiency Gene Panel, Varies

Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of a hereditary combined humoral and cell-mediated immunodeficiency (CID) Establishing a diagnosis of a combined immunodeficiency...

ESTF - Overview: Estrogens, Estrone (E1) and Estradiol (E2), Fractionated, Serum

Simultaneous high-sensitivity determination of serum estrone and estradiol levels Situations requiring either higher sensitivity estradiol measurement, estrone measurement, or both, including -As part of the diagnosis and workup of...

PFAPC - Overview: Fatty Acid Profile, Comprehensive (C8-C26), Plasma

Monitoring patients undergoing diet therapy for mitochondrial or peroxisomal disorders (possibly inducing essential fatty acid deficiency in response to restricted fat intake) using plasma specimens Monitoring treatment of essential fatty...

FAPCP - Overview: Fatty Acid Profile, Comprehensive (C8-C26), Serum

Monitoring patients undergoing diet therapy for mitochondrial or peroxisomal disorders (possibly inducing essential fatty acid deficiency in response to restricted fat intake) using serum specimens Monitoring treatment of essential fatty...

ALKD5 - Overview: Anaplastic Lymphoma Kinase (ALK[D5F3]) Immunostain, Technical Component Only

Identification of anaplastic lymphoma kinase overexpression Diagnosis of lung adenocarcinoma and inflammatory myofibroblastic tumor

ALCU - Overview: Aluminum/Creatinine Ratio, Urine

Measurement of aluminum concentration as a part of assessing for aluminum exposure

AERMC - Overview: Aeromonas Culture, Feces

Determining whether Aeromonas species may be the cause of diarrhea This test is generally not useful for patients hospitalized more than 3 days because the yield from specimens from these patients is very low, as is the likelihood of...

AAMSD - Overview: Amino Acids, Maple Syrup Urine Disease Panel, Plasma

Follow-up of patients with maple syrup urine disease Monitoring of dietary compliance for patients with maple syrup urine disease

DRPL - Overview: Dentatorubral-Pallidoluysian Atrophy (DRPLA) Gene Analysis, Varies

Confirming the diagnosis of dentatorubral-pallidoluysian atrophy (DRPLA) for symptomatic patients Predictive testing for individuals with a family history of DRPLA and a documented expansion in the ATN1 gene in an affected family member

F2ISO - Overview: F2-Isoprostanes, Random, Urine

Assessment of in vivo lipid peroxidation Considered to be an index of systemic oxidative stress over time

FMBNY - Overview: Fetomaternal Bleed, New York, Blood

Determining the volume of fetal-to-maternal hemorrhage for the purposes of recommending an increased dose of the Rh immune globulin This test is used only for specimens collected in New York state.

COKEX - Overview: Cocaine and Metabolite Confirmation, Chain of Custody, Random, Urine

Detecting and confirming drug abuse involving cocaine Chain of custody is required whenever the results of testing could be used in a court of law. Its purpose is to protect the rights of the individual contributing the specimen by...

FMB - Overview: Fetomaternal Bleed, Flow Cytometry, Blood

Determining the volume of fetal-to-maternal hemorrhage for the purposes of recommending an increased dose of the Rh immune globulin

EM - Overview: Electron Microscopy, Varies

Providing information to aid in the diagnosis of medical disorders such as storage diseases, CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy), and primary ciliary dyskinesia

T790M - Overview: Cell-Free DNA EGFR T790M Mutation Analysis, Blood

Determination of EGFR T790M mutation status in blood specimens as an alternative to invasive tissue biopsies Identification of patients with non-small cell lung cancer who harbor a T790M mutation and may benefit from specific EGFR-targeted...

C5AG - Overview: C5 Complement, Antigen, Serum

Diagnosis of C5 deficiency Investigation of a patient with an absent total complement (CH50) level

C1ES - Overview: C1 Esterase Inhibitor Antigen, Serum

Diagnosis of hereditary angioedema Monitoring levels of C1 esterase inhibitor in response to therapy

BAP - Overview: Bone Alkaline Phosphatase, Serum

Diagnosis and assessment of severity of metabolic bone disease including Paget disease, osteomalacia, and other states of high bone turnover Monitoring efficacy of antiresorptive therapies including postmenopausal osteoporosis treatment...

CEE20 - Overview: CD20 Cell Expression Evaluation, Varies

Detecting cell-surface antigens on malignant cells that are potential therapeutic antibody targets, specifically CD20 Determining the eligibility of patients for monoclonal antibody therapies Monitoring response to the therapeutic...

CLZ - Overview: Clozapine, Serum

Monitoring patient compliance of clozapine treatment An aid to achieving desired serum levels

CHLBF - Overview: Cholesterol, Body Fluid

Aiding in the diagnosis of a cholesterol effusion or cholesterol-rich pseudochylous effusion in body fluids Distinguishing between chylous and pseudochylous pleural effusions Distinguishing between malignant and nonmalignant ascites

CEE49 - Overview: CD49d Cell Expression Evaluation, Varies

Detecting cell-surface antigens on malignant cells that are potential therapeutic antibody targets, specifically CD49d Determining the eligibility of patients for monoclonal antibody therapies Monitoring response to the therapeutic...

REVEI - Overview: Erythrocytosis Interpretation

Interpretation of Erythrocytosis Evaluation profile test Definitive, comprehensive, and economical evaluation of an individual with JAK2-negative erythrocytosis associated with lifelong sustained increased hemoglobin or hematocrit

ECULI - Overview: Eculizumab, Serum

Assessing the response to eculizumab therapy Assessing the need for dose escalation Evaluating the potential for dose de-escalation or discontinuation of therapy in remission states Monitoring patients who need to be above a certain...

GDUCR - Overview: Gadolinium/Creatinine Ratio, Random, Urine

Assessing chronic exposure and monitoring effectiveness of dialysis in a random urine collection

GDCU - Overview: Gadolinium/Creatinine Ratio, Urine

Measurement of gadolinium concentration for assessing chronic exposure and monitoring effectiveness of dialysis using a random urine collection

HAEVI - Overview: Hemolytic Anemia Interpretation

Interpretation of the results for the evaluation of hemolytic anemia Evaluation of lifelong or inherited hemolytic anemias, including red cell membrane disorders, unstable or abnormal hemoglobin variants, and red cell enzyme disorders

IL5P - Overview: Interleukin 5, Plasma

Evaluation of patients with disorders known to be associated with hypereosinophilia

BCGBM - Overview: Immunoglobulin Gene Rearrangement, PCR, Bone Marrow

Determining whether a B-cell or plasma cell population is polyclonal or monoclonal using bone marrow specimens Identifying neoplastic cells as having B-cell or plasma cell differentiation Monitoring for a persistent neoplasm by...

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Cystatin C - Insights

Learn how our cystatin C testing provides an index of glomerular filtration rate, which is the best indicator of overall kidney health and function....

Hepatitis C Virus Genotypic Antiviral Drug Resistance [Test in Focus] - Insights

Joseph Yao, M.D., gives an overview of this new test available through Mayo Clinic Laboratories. He discusses when this testing should be ordered, how this testing improves upon other testing approaches, and what clinical action can be...

testing_algorithm_for_the_screening_and_diagnosis_of_hepatitis_c.pdf

Education and Research (MFMER). All rights reserved. 02/2022 Hepatitis C: Testing Algorithm for Screening and Diagnosis HCVQN / Hepatitis C Virus (HCV) RNA Detection and Quantification by Real-Time Reverse...

https://news.mayocliniclabs.com/mc2775-782/

FO U R RE AL -W O RL D C O LL AB O RA TI VE E XA M PL ES to Mayo Clinic diagnostics C O N N E C T I N G Pharma and biotech TABLE OF CONTENTS What makes a good testing partner? Case study 1 Gastrointestinal...

Algorithms - Mayo Clinic Laboratories

Algorithms A B C D E F G H I J