UNHB - Overview: Hemoglobin Stability, Blood

Work-up of congenital hemolytic anemias

23FBG - Overview: Fibroblast Growth Factor-23 (FGF23), In Situ Hybridization

Assessing fibroblast growth factor-23 (FGF23) expression

LEU - Overview: Fecal Leukocytes, Feces

Suggesting the presence of pathogens such as Salmonella, Shigella, and amebiasis

MURA - Overview: Lysozyme (Muramidase), Plasma

As a screening test for ocular sarcoidosis Confirming marked increases in the granulocyte or monocyte pools as in granulocytic or monocytic leukemias, myeloproliferative disorders, and malignant histiocytosis Following the course of...

PBOU - Overview: Lead Occupational Exposure, Random, Urine

Detecting clinically significant lead exposure due to occupational exposure in random urine specimens This test is not a substitute for blood lead screening.

TPI1 - Overview: Triosephosphate Isomerase Enzyme Activity, Blood

Evaluating individuals with chronic nonspherocytic hemolytic anemia Evaluating individuals with early onset neurologic impairment Genetic counseling for families with triosephosphate isomerase deficiency

CEASF - Overview: Carcinoembryonic Antigen (CEA), Spinal Fluid

Detecting meningeal carcinomatosis and intradural or extradural infiltration Differentiating brain parenchymal metastasis from adenocarcinoma or squamous-cell carcinoma

CZPS - Overview: Clonazepam and 7-Aminoclonazepam, Serum

Assessing patient compliance Monitoring for appropriate therapeutic level Assessing clonazepam toxicity

CAFF - Overview: Caffeine, Serum

Monitoring caffeine therapy in neonates Assessing caffeine toxicity in neonates

CDP - Overview: Chlordiazepoxide and Metabolite, Serum

Monitoring chlordiazepoxide therapy Assessing toxicity

DIA - Overview: Diazepam and Nordiazepam, Serum

Assessing compliance Monitoring for appropriate therapeutic level Assessing diazepam toxicity

MPLR - Overview: MPL Exon 10 Mutation Detection, Reflex, Varies

Aiding in the distinction between a reactive cytosis and a chronic myeloproliferative disorder Evaluates for mutations in MPL in an algorithmic process for the MPNR / Myeloproliferative Neoplasm, JAK2 V617F with Reflex to CALR and MPL,...

ETGL - Overview: Ethylene Glycol, Serum

Confirming and monitoring ethylene glycol toxicity

WGSDX - Overview: Whole Genome Sequencing for Hereditary Disorders, Varies

Serving as a first-tier test to identify a molecular diagnosis in patients with suspected genetic disorders, which can allow for: -Better understanding of the natural history/prognosis -Targeted management (anticipatory guidance, management...

TRMP - Overview: Trimipramine, Serum

Monitoring trimipramine concentration during therapy Evaluating potential trimipramine toxicity May aid in evaluating patient compliance

VITE - Overview: Vitamin E, Serum

Monitoring of Vitamin E supplementation/treatment Potentially detecting Vitamin E overdoses

IGD - Overview: Immunoglobulin D (IgD), Serum

Providing information on the humoral immune status Identifying an IgD monoclonal gammopathy

FIBAG - Overview: Fibrinogen Antigen, Plasma

Evaluation of fibrinogen deficiency Measuring fibrinogen in patients with elevated plasma levels of fibrin degradation products, patients receiving heparin, and in patients with antibodies to thrombin (following surgical use of topical...

AFOLR - Overview: Folate Receptor Alpha (FOLR1), Semi-Quantitative Immunohistochemistry, Manual

Diagnosis of epithelial ovarian cancer that may be eligible for treatment with an anti-folate receptor 1 protein antibody

FELBA - Overview: Felbamate (Felbatol), Serum

Determining whether a poor therapeutic response is attributable to noncompliance or lack of drug effectiveness Monitoring changes in serum concentrations resulting from interactions with coadministered drugs such as barbiturates and...

LID - Overview: Lidocaine, Serum

Assessing optimal lidocaine dosing during the acute management of ventricular arrhythmias following myocardial infarction or during cardiac manipulation such as surgery Assessing potential lidocaine toxicity

LEVE - Overview: Levetiracetam, Serum

Monitoring serum concentration of levetiracetam, particularly in patients with kidney disease Assessing compliance with levetiracetam therapy Assessing potential toxicity of levetiracetam

ALKLC - Overview: Anaplastic Lymphoma Kinase for Lung Cancer, Immunohistochemistry

Identification of anaplastic lymphoma kinase overexpression Diagnosis of inflammatory myofibroblastic tumor, anaplastic large-cell lymphoma, and for targeted therapy of lung adenocarcinoma

NOTRP - Overview: Nortriptyline, Serum

Monitoring nortriptyline concentration during therapy Evaluating potential nortriptyline toxicity May aid in evaluating patient compliance

TPIC - Overview: Triosephosphate Isomerase Enzyme Activity, Blood

Evaluating individuals with chronic nonspherocytic hemolytic anemia Evaluating individuals with early onset neurologic impairment Genetic counseling for families with triosephosphate isomerase deficiency

CULAF - Overview: Culture for Genetic Testing, Amniotic Fluid

Producing amniocyte cultures that can be used for genetic analysis

DXPIN - Overview: Doxepin and Nordoxepin, Serum

Monitoring doxepin therapy Evaluating potential doxepin toxicity Evaluating patient compliance

DESPR - Overview: Desipramine, Serum

Monitoring serum concentration of desipramine during therapy Evaluating potential desipramine toxicity May aid in evaluating patient compliance

CRE2 - Overview: Creatinine, Urine

Normalization of urinary analytes to account for the variation in urinary concentrations between individuals when using random urine collections

CRETR - Overview: Creatinine, Random, Urine

Normalization of urinary analytes to account for the variation in urinary concentrations between individuals when using random urine collections

PA - Overview: Procainamide and N-Acetylprocainamide, Serum

Monitoring therapy with procainamide Assessing compliance Evaluating procainamide toxicity

FRUCT - Overview: Fructosamine, Serum

Monitoring intermediate (1-3 weeks) glycemic control Monitoring glycemic control in patients with shortened red blood cell survival

RCVBS - Overview: Recoverin-IgG Antibody, Immunoblot, Serum

Evaluating patients with suspected paraneoplastic retinopathy accompanying small cell carcinoma

TCP - Overview: T-Cell Subsets, Naive, Memory, and Activated, Blood

Determining the presence of naive, memory, and activated T cells in various clinical contexts including autoimmune diseases, immunodeficiency states, T-cell recovery post-hematopoietic stem cell transplant, DiGeorge syndrome, and as a...

AVWPR - Overview: von Willebrand Disease Profile, Plasma

Detection of deficiency or abnormality of von Willebrand factor (VWF) and related deficiency of factor VIII coagulant activity Subtyping von Willebrand disease (VWD) as type 1 (most common), type 2 variants (less common), or type 3...

LPMGF - Overview: Lymphocyte Proliferation to Mitogens, Blood

Assessing T-cell function in patients on immunosuppressive therapy, including solid-organ transplant patients Evaluating patients suspected of having impairment in cellular immunity Evaluation of T-cell function in patients with primary...

LPAGF - Overview: Lymphocyte Proliferation to Antigens, Blood

Assessing T-cell function in patients on immunosuppressive therapy, including solid-organ transplant patients Evaluating patients suspected of having impairment in cellular immunity Evaluation of T-cell function in patients with primary...

RPDE - Overview: Rapidly Progressive Dementia Evaluation, Spinal Fluid

Evaluation of individuals presenting with rapidly progressive dementia of uncertain disease etiology and a differential diagnosis of Creutzfeldt-Jakob disease and rapidly progressive Alzheimer disease

ALPSG - Overview: Autoimmune Lymphoproliferative Syndrome (ALPS) Gene Panel, Varies

Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of autoimmune lymphoproliferative syndrome (ALPS) or related disorders Establishing a diagnosis of ALPS or a related disorder, allowing...

TRECS - Overview: T-Cell Receptor Excision Circles Analysis, Blood

Measuring T-cell output or reconstitution (thymopoiesis) following hematopoietic cell transplantation or highly active antiretroviral therapy Evaluating thymic function in patients with cellular or combined inborn errors of immunity...

IMMAU - Overview: Inborn Errors of Immunity with Immune Dysregulation and Autoimmunity Gene Panel, Varies

Providing a comprehensive genetic evaluation for patients with a personal or family history suggestive of an inborn error of immunity (IEI) associated with immune dysregulation or autoimmunity Establishing a diagnosis of an IEI, allowing...

QNKS - Overview: Natural Killer (NK)/Natural Killer T-Cell Subsets, Quantitative, Blood

Quantitation of the major natural killer (NK)-cell subsets relative to total NK cells (NK cell subsets) or total lymphocytes (NK T cells) Assessment in the following clinical contexts: HIV, primary immune deficiencies with NK cell...

DOGPF - Overview: Dog Dander, IgE, with Reflex to Dog Dander Components, IgE, Serum

Evaluating patients with suspected dog dander allergy

TIKLB - Overview: Tick-Borne Panel, Molecular Detection, PCR, Blood

Evaluating patients with suspected human monocytic ehrlichiosis, human granulocytic anaplasmosis, babesiosis, or Borrelia miyamotoi infection Evaluating patients with a history of, or suspected, tick exposure who are presenting with...

MEV1 - Overview: Methemoglobinemia Evaluation, Blood

Diagnosis of methemoglobinemia and sulfhemoglobinemia and possible hereditary (congenital) causes Differentiation of methemoglobinemia and sulfhemoglobinemia from other causes of cyanosis (eg, congenital heart disease)

OTP - Overview: Orthopedia Homeobox Protein (OTP) Immunostain, Technical Component Only

Distinguishing lung carcinoid tumors from metastatic neuroendocrine tumors

288PD - Overview: Programmed Death-Ligand 1 (PD-L1) (28-8), Semi-Quantitative Immunohistochemistry, Manual

Identification of neoplasms expressing programmed cell death 1-ligand 1(clone 28-8)

HPP - Overview: Pancreatic Polypeptide, Plasma

Detecting pancreatic endocrine tumors Assessing vagal nerve function after meal or sham feeding

HIAAP - Overview: 5-Hydroxyindoleacetic Acid, Plasma

Biochemical diagnosis and monitoring of intestinal carcinoid syndrome using a plasma specimen

YAP1 - Overview: Yes-Associated Protein (YAP) Immunostain, Technical Component Only

Identification and differentiation of medulloblastomas