T46CS - Overview: Tripartite Motif-Containing Protein 46 (TRIM46) IgG, Cell Binding Assay, Serum

Detecting tripartite motif-containing protein 46 (TRIM46)-IgG by cell-binding assay using serum specimens Evaluation of an autoimmune/paraneoplastic neurological syndrome among patients presenting with cerebellar ataxia, encephalitis, or...

CHLGP - Overview: Cholestasis Gene Panel, Varies

Establishing a molecular diagnosis for patients with monogenic cholestasis Identifying variants within genes known to be associated with primary, monogenic cholestasis, allowing for predictive testing of at-risk family members This panel...

VEGF - Overview: Vascular Endothelial Growth Factor, Plasma

Evaluation of patients with suspected POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome, particularly in differentiating from other forms of polyneuropathy and/or monoclonal plasma cell...

RBR - Overview: Retinol-Binding Protein, Random, Urine

Assessing renal tubular injury or dysfunction using random urine collections Screening for other tubular abnormalities Detecting chronic asymptomatic renal tubular dysfunction.(2)

CD103 - Overview: CD103 Immunostain, Technical Component Only

Aids in the diagnosis of hairy cell leukemia and marginal zone lymphomas

UEBF - Overview: Urea Nitrogen, Body Fluid

Identifying the presence of urine as a cause for accumulation of fluid in a body compartment Assessing adequacy of peritoneal dialysis treatment protocols

HNF1B - Overview: Hepatocyte Nuclear Factor 1Beta Immunostain, Technical Component Only

Diagnosis of ovarian clear cell carcinoma and endometrial clear cell carcinoma

HCG - Overview: Human Chorionic Gonadotropin (hCG) Immunostain, Technical Component Only

Identification human chorionic gonadotropin expression in neoplasms

H1083 - Overview: HIK1083 Immunostain, Technical Component Only

Diagnosis of gastric-type endocervical adenocarcinoma

KRT34 - Overview: Keratin (34BE12) Immunostain, Technical Component Only

Identification of cells expressing high-molecular-weight cytokeratin

AREC - Overview: Androgen Receptor Immunostain, Technical Component Only

Identification of tumors that express androgen receptor

STFR - Overview: Soluble Transferrin Receptor (sTfR), Serum

Evaluation of suspected iron deficiency in patients who may have inflammation, infection, or chronic disease and other conditions in which ferritin concentration does not correlate with iron status, including: -Cystic fibrosis patients who...

TRBC3 - Overview: T-Cell Receptor Constant Beta Chain (TRBC1) +CD3 Immunostain, Technical Component Only

Determination of T-cell clonality in T-cell neoplasms

TRBC1 - Overview: T-Cell Receptor Constant Beta Chain (TRBC1) Immunostain, Technical Component Only

Determination of T-cell clonality in T-cell neoplasms

C8FX - Overview: C8 Complement, Functional, Serum

Diagnosis of C8 deficiency Investigation of a patient with an undetectable total hemolytic complement level

PEPAN - Overview: Comprehensive Peripheral Neuropathy Gene Panel, Varies

Establishing a molecular diagnosis for patients with peripheral neuropathy Identifying variants within genes known to be associated with peripheral neuropathy, allowing for predictive testing of at-risk family members

CAORG - Overview: Comprehensive Marfan, Loeys-Dietz, Ehlers-Danlos, and Aortopathy Gene Panel, Varies

Providing a genetic evaluation for patients with a personal or family history suggestive of hereditary aortic disease Establishing a diagnosis for a variety of hereditary conditions involving aortic disease or overlapping clinical...

DWPAN - Overview: Comprehensive Distal Weakness Gene Panel, Varies

Establishing a molecular diagnosis for patients with distal weakness Identifying variants within genes known to be associated with distal weakness, allowing for predictive testing of at-risk family members

PKC - Overview: Pyruvate Kinase Enzyme Activity, Blood

Evaluation of nonspherocytic hemolytic anemia as a part of a profile Evaluation of neonatal anemia or jaundice Evaluation of unexplained noninfectious hepatic failure Evaluation of unexplained iron overload Evaluation of unusually...

PK1 - Overview: Pyruvate Kinase Enzyme Activity, Blood

Evaluation of nonspherocytic hemolytic anemia Evaluation of neonatal anemia or jaundice Evaluation of unexplained noninfectious hepatic failure Evaluation of unexplained iron overload Evaluation of unusually severe hemoglobin S...

P63 - Overview: p63 Immunostain, Technical Component Only

Aiding in identifying squamous, urothelial, or myoepithelial differentiation in tumors

GRANB - Overview: Granzyme B Immunostain, Technical Component Only

Classification of lymphomas

GCET - Overview: Germinal Center B-cell Expressed Transcript 1 Immunostain, Technical Component Only

Classification of lymphomas

ECADB - Overview: E-Cadherin Immunostain, Bone Marrow, Technical Component Only

Differentiation between lobular and ductal neoplasms of the breast

EXT2 - Overview: Exostosin 2 (EXT2) Immunostain, Technical Component Only

Identification of exostosin 2 associated membranous nephropathy

SPSM - Overview: Morphology Evaluation (Special Smear), Blood

Detecting disease states or syndromes of the white blood cells, red blood cells, or platelet cell lines of a patient's peripheral blood

ICOSI - Overview: ICOS (CD278), Immunostain, Technical Component Only

Classification of T-cell lymphomas

LMO2 - Overview: LIM Domain Only 2 (LMO2) Immunostain, Technical Component Only

Classification of lymphomas

AACYL - Overview: Aminoacylase-1 Deficiency, Urine

Follow-up quantitation of abnormal organic acid elevations of N-acetylated amino acids, in particular N-acetylalanine, N-acetylglycine, N-acetylmethionine, and N-acetylglutamic acid Diagnosis of individuals with aminoacylase-1...

C5DCU - Overview: C5-DC Acylcarnitine, Quantitative, Random, Urine

Evaluation of patients with an abnormal newborn screen showing elevations of glutarylcarnitine Diagnosis of glutaric aciduria type 1 deficiency

MPLVS - Overview: MPL Exon 10 Mutation Detection, Varies

Aiding in the distinction between a reactive cytosis and a myeloproliferative neoplasm

CSMRT - Overview: mSMART Plasma Cell Proliferative Disorder, Pre-Analysis Cell Sorting, Bone Marrow

Risk stratification of patients with multiple myeloma, which can assist in determining treatment and management decisions Sorting plasma cells for fluorescence in situ hybridization analysis Risk stratification of patients with newly...

SUDC - Overview: Sudden Cardiac Death Pathology Consultation

Identifying specific causes contributing to sudden cardiac death

SMAD4 - Overview: SMAD4 Immunostain, Technical Component Only

Identification of loss of SMAD4 (mothers against decapentaplegic homolog 4 drosophila) expression within pancreatic ductal adenocarcinoma

CD11C - Overview: CD11c Immunostain, Technical Component Only

Aiding in the diagnosis of hematological malignancies and identification of cells of the macrophage/dendritic cell lineage within tissues

EBNA2 - Overview: Epstein Barr Nuclear Antigen 2 (EBNA2) Immunostain, Technical Component Only

Identification of Epstein Barr virus infection in normal, inflammatory, and neoplastic tissues

KRT7 - Overview: Keratin 7 (KRT7) Immunostain, Technical Component Only

Aiding in determining the primary site in carcinomas of unknown origin

FACR8 - Overview: Factor 8 Related Antigen Immunostain, Technical Component Only

Marker of endothelial cell lineage

PRL - Overview: Prolactin, Serum

Aiding in evaluation of pituitary tumors, amenorrhea, galactorrhea, infertility, and hypogonadism Monitoring therapy of prolactin-producing tumors

PIK3T - Overview: PIK3CA Mutation Analysis, Tumor

Identification of hormone receptor positive and human epidermal growth factor receptor 2 negative (HR+/HER2-) advanced breast cancer tumors that may be eligible for treatment with targeted kinase inhibitor therapy (eg, alpelisib).

PIPU - Overview: Pipecolic Acid, Random, Urine

Differentiating between disorders of peroxisomal biogenesis (eg, Zellweger syndrome) and disorders with loss of a single peroxisomal function Detecting abnormal elevations of pipecolic acid in urine

PKU - Overview: Phenylalanine and Tyrosine, Plasma

Monitoring effectiveness of dietary therapy in patients with hyperphenylalaninemia

HEXAZ - Overview: Tay-Sachs Disease, HEXA Gene, Full Gene Analysis, Varies

Second-tier test for confirming a biochemical diagnosis of Tay-Sachs disease (TSD) Carrier testing of individuals with a family history of TSD but an affected individual is not available for testing or disease-causing mutations have not...

VWFMP - Overview: von Willebrand Factor Multimer Analysis, Plasma

As a reflex component of several coagulation consultation unit codes, when indicated When results of complementary laboratory tests are abnormally low or discordant (eg, F8A / Coagulation Factor VIII Activity Assay, Plasma; VWACT / von...

RB24 - Overview: Retinol-Binding Protein, 24 Hour, Urine

Assessing renal tubular injury or dysfunction Screening for other tubular abnormalities Detecting chronic asymptomatic renal tubular dysfunction.(2)

PIPA - Overview: Pipecolic Acid, Serum

Differentiating between disorders of peroxisomal biogenesis (eg, Zellweger syndrome) and disorders with loss of a single peroxisomal function Detecting abnormal elevations of pipecolic acid in serum

RISA - Overview: Risankizumab, Serum

Assessing the response to risankizumab therapy Assessing the need for dose escalation Evaluating potential changes or discontinuation of therapy Monitoring patients who need to be above a certain risankizumab concentration to improve the...

HPFH - Overview: Hemoglobin F Distribution, Blood

Distinguishing large deletional hereditary persistence of fetal hemoglobin from other conditions with increased percentage of fetal hemoglobin (Hb F) Determining the distribution of Hb F within red blood cells

FSH - Overview: Follicle-Stimulating Hormone (FSH), Serum

An adjunct in the evaluation of menstrual irregularities Evaluating patients with suspected hypogonadism Predicting ovulation Evaluating infertility Diagnosing pituitary disorders

ACMFS - Overview: Acetylcholine Receptor Modulating Antibody, Flow Cytometry Assay, Serum

Diagnosis for autoimmune myasthenia gravis (MG) in adults and children Distinguishing autoimmune from congenital MG in adults and children or other acquired forms of neuromuscular junction transmission disorders. This test is a...